R4 262+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — JNB
May 18 — May 251
1 adult
1 adult, Economy, 0 bags

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 18 April 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 18/9

14:36-9:00

2 stops35h 24m

Johannesburg OR Tambo

Mon 5/10

20:55-21:44

2 stops31h 49m

R26 240

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 18/9

8:00-18:30

3 stops27h 30m

Johannesburg OR Tambo

Tue 6/10

19:00-19:25

2 stops31h 25m

R28 837

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 20/9

11:04-19:40

1 stop25h 36m

Johannesburg OR Tambo

Sun 4/10

23:15-22:26

2 stops30h 11m

R30 322

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 29/5

5:27-21:20

2 stops32h 53m

Johannesburg OR Tambo

Fri 5/6

18:00-16:48

2 stops29h 48m

R31 972

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 4/6

10:26-21:20

2 stops27h 54m

Johannesburg OR Tambo

Mon 15/6

18:00-17:23

2 stops30h 23m

R32 070

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 2/6

10:26-21:20

2 stops27h 54m

Johannesburg OR Tambo

Tue 9/6

18:00-16:54

2 stops29h 54m

R32 755

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 28/5

18:50-18:30

2 stops40h 40m

Johannesburg OR Tambo

Thu 4/6

19:00-19:25

2 stops31h 25m

R32 837

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 4/6

10:26-21:20

2 stops27h 54m

Johannesburg OR Tambo

Mon 15/6

23:15-22:31

2 stops30h 16m

R32 870

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 1/6

10:26-21:20

2 stops27h 54m

Johannesburg OR Tambo

Mon 8/6

18:00-17:54

2 stops30h 54m

R32 886
Fastest return journey

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 21/9

14:15-19:40

1 stop22h 25m

Johannesburg OR Tambo

Fri 2/10

21:55-13:22

1 stop22h 27m

R34 535

Flights are sorted by cheapest return flights first.

Deals found on 14/4

Showing 1-10 of 14 resultsSorted by cheapest first
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Best time to book a flight from Des Moines

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Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 April 2026.

  • What are the most popular destinations to fly to from Des Moines?

    The most selected flight destinations from Des Moines for the current month are Las Vegas, Denver, Cancún. While Las Vegas, Denver, Los Angeles are the top choices made by travellers year-round.

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How does Cheapflights help users find flights from Des Moines?

Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Des Moines with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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