R2 818+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — JNB
juil. 10 — juil. 171
1 adult
1 adult, Economy, 0 bags

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 juin 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

sam. 31/10

6:15-13:05

2 stops23h 50m

Johannesburg OR Tambo

mer. 18/11

14:30-12:30

3 stops30h 00m

R28 016

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

ven. 11/9

16:15-19:40

1 stop20h 25m

Johannesburg OR Tambo

dim. 20/9

21:55-18:00

1 stop27h 05m

R30 751

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

ven. 4/9

6:00-18:30

3 stops29h 30m

Johannesburg OR Tambo

jeu. 10/9

22:00-23:33

2 stops32h 33m

R31 641

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

dim. 21/6

6:00-13:25

2 stops24h 25m

Johannesburg OR Tambo

dim. 12/7

14:30-21:22

3 stops37h 52m

R32 218
Fastest return journey

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

dim. 21/6

11:28-19:40

1 stop25h 12m

Johannesburg OR Tambo

dim. 12/7

21:55-10:45

1 stop19h 50m

R32 729

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

dim. 21/6

11:28-21:20

2 stops26h 52m

Johannesburg OR Tambo

dim. 12/7

23:15-21:08

2 stops28h 53m

R33 157
Cheapest one-way

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

mar. 23/6

11:26-18:30

2 stops24h 04m

R19 792

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

mer. 1/7

17:34-9:50

3 stops57h 16m

R22 033
Fastest single journey

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

ven. 3/7

17:00-19:40

1 stop19h 40m

R22 198

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

ven. 24/7

14:25-19:40

1 stop22h 15m

R22 198

Flights are sorted by cheapest return flights first.

Deals found on 9/6

Showing 1-10 of 12 resultsSorted by cheapest first
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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Des Moines?

From Des Moines you can expect to find greater availability for the following destinations: Chicago (602 flights per day), Detroit (146 flights per day) and Atlanta (139 flights per day).

Chicago
Chicago
From R8 320

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Chicago, with prices starting at R8 320. Explore other affordable destinations below.

Chicago
Chicago
From R8 320

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Direct flights from Iowa

Book a direct flight from one of these other cities located in Iowa.
Direct flights from Cedar Rapids

Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 juin 2026.

  • What are the most popular destinations to fly to from Des Moines?

    The most selected flight destinations from Des Moines for the current month are Denver, Las Vegas, Los Angeles. While Las Vegas, Denver, Los Angeles are the top choices made by travellers year-round.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as R8 320 to Chicago O'Hare Intl Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R8 320 to fly from Des Moines.

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Des Moines?

Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Des Moines with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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