R1 263+ Cheap flights from Des Moines
This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — JNB
Nov 7 — Nov 141
Find flights from Des Moines within your budget
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 8 October 2026. In the last 7 days, Cheapflights users made a total of 7 457 451 searches
Fly to
Route
Depart
Return
Cheapest return flight
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Wed 6/1
6:55-13:10
1 stop6h 15m
Minneapolis St Paul
Wed 31/12
0:00-0:00
Nonstop0h 00m
R1 263
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Mon 7/12
6:00-9:45
1 stop3h 45m
Minneapolis St Paul
Wed 31/12
0:00-0:00
Nonstop0h 00m
R1 263
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Wed 9/12
15:30-22:20
1 stop6h 50m
Minneapolis St Paul
Wed 31/12
0:00-0:00
Nonstop0h 00m
R1 263
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Fri 6/11
5:25-9:35
1 stop4h 10m
Minneapolis St Paul
Wed 31/12
0:00-0:00
Nonstop0h 00m
R1 545
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Wed 23/12
6:35-7:54
Nonstop1h 19m
Minneapolis St Paul
Wed 30/12
18:30-19:59
Nonstop1h 29m
R3 307
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Tue 1/12
16:53-18:12
Nonstop1h 19m
Minneapolis St Paul
Sun 6/12
14:43-16:11
Nonstop1h 28m
R3 307
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Wed 16/12
16:53-18:12
Nonstop1h 19m
Minneapolis St Paul
Sat 19/12
18:30-19:59
Nonstop1h 29m
R3 307
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Tue 27/10
5:35-9:20
1 stop3h 45m
Minneapolis St Paul
Wed 28/10
7:15-11:30
1 stop4h 15m
R3 423
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Fri 6/11
6:55-8:11
Nonstop1h 16m
Minneapolis St Paul
Wed 31/12
0:00-0:00
Nonstop0h 00m
R3 639
Des MoinesMinneapolis
DSM Des Moines - MSP Minneapolis St Paul
DSMMSP
Des Moines
Fri 4/12
16:53-18:12
Nonstop1h 19m
Minneapolis St Paul
Wed 31/12
0:00-0:00
Nonstop0h 00m
R3 639
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Des Moines
Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
DSM-JNB
DSM-MSP
DSM-IAH
DSM-AMS
DSM-BOM
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Travel insights for flights from Des Moines
Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.
DSM-JNB
DSM-MSP
DSM-IAH
DSM-AMS
DSM-BOM
What are popular destinations to fly to from Des Moines?
From Des Moines you can expect to find greater availability for the following destinations: Chicago (566 flights per day), Dallas (112 flights per day) and Denver (49 flights per day).
What is the cheapest place to fly to from Des Moines?
The cheapest city to fly to from Des Moines is Chicago, with prices starting at R8 389. Explore other affordable destinations below.
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Airports servicing Des Moines
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Fly from other United States cities
Consider departing from one of these cities also located in United States. Flight origins are based on user searches made on Cheapflights and were last updated on 8 October 2026.
Popular flight searches
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Related info for your journey
Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 8 October 2026.
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