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R2 481+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — JNB
Dec 13 — Dec 201
1 adult
1 adult, Economy, 0 bags

What to know about flights from Des Moines

Discover essential information about flights departing from Des Moines, including flight schedules, destinations, airlines operating at the Des Moines airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 13 November 2025.

Good round-trip deal

R31 102 or less

Good one-way deal

R1 786 or less
Price to beat on a round-trip flight from Des Moines.
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Price to beat on a one-way flight from Des Moines.
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Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 13 November 2025.

Thu 5/315:25DSM - JNB
2 stops32h 10mAmerican Airlines
Mon 9/319:35JNB - DSM
2 stops33h 17mAmerican Airlines
Deal found 10/11R21 118
Sun 5/417:52DSM - JNB
2 stops39h 18mQatar Airways
Sun 12/420:40JNB - DSM
2 stops33h 00mQatar Airways
Deal found 11/11R22 589
Sun 5/411:04DSM - JNB
1 stop25h 36mDelta
Sun 12/421:55JNB - DSM
1 stop31h 34mDelta
Deal found 12/11R30 752
Sun 5/411:30DSM - JNB
3 stops38h 05mAir Canada
Sun 12/419:30JNB - DSM
3 stops33h 22mAir Canada
Deal found 12/11R38 162
Thu 5/311:28DSM - JNB
1 stop23h 32mVirgin Atlantic
Mon 9/322:00JNB - DSM
2 stops29h 53mVirgin Atlantic
Deal found 12/11R44 426
Sun 28/128:00DSM - JNB
2 stops26h 35mUnited Airlines
Sun 4/119:45JNB - DSM
2 stops33h 55mUnited Airlines
Deal found 12/11R44 854
Sun 28/1218:46DSM - JNB
2 stops28h 19mLufthansa
Sun 4/110:10JNB - DSM
2 stops43h 30mLufthansa
Deal found 13/11R45 281

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 13 November 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 5/3

15:25-7:35

2 stops32h 10m

Johannesburg OR Tambo

Mon 9/3

19:35-21:52

2 stops33h 17m

R21 118

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 5/4

17:52-16:10

2 stops39h 18m

Johannesburg OR Tambo

Sun 12/4

20:40-22:40

2 stops57h 00m

R23 702

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 5/4

11:04-19:40

1 stop25h 36m

Johannesburg OR Tambo

Sun 12/4

21:55-22:29

1 stop31h 34m

R30 752

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 5/4

11:30-8:35

3 stops38h 05m

Johannesburg OR Tambo

Sun 12/4

19:30-21:52

3 stops33h 22m

R38 162

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 5/3

11:28-19:00

1 stop23h 32m

Johannesburg OR Tambo

Mon 9/3

22:00-20:53

2 stops29h 53m

R44 426

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 28/12

8:00-18:35

2 stops26h 35m

Johannesburg OR Tambo

Sun 4/1

19:45-21:40

2 stops33h 55m

R44 854

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 28/12

18:46-7:05

2 stops28h 19m

Johannesburg OR Tambo

Sun 4/1

10:10-21:40

2 stops43h 30m

R45 281

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 15/3

18:20-8:20

3 stops55h 00m

R15 539

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 15/3

14:48-3:55

2 stops30h 07m

R16 001

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 17/2

18:38-10:25

2 stops31h 47m

R64 226

Flights are sorted by cheapest return flights first.

Deals found on 11/11

Showing 1-10 of 15 results
1
2

Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

Which airlines fly from Des Moines?

When flying from Des Moines check dates and pricing for the following: British Airways. As it departs for the following popular destinations: Johannesburg.

British Airways
British Airways
From R23 886

What are popular destinations to fly to from Des Moines?

From Des Moines you can expect to find greater availability for the following destinations: Chicago (566 flights per day), Atlanta (136 flights per day) and Detroit (134 flights per day).

Denver Intl
Denver Intl
From R1 786
Minneapolis St Paul
Minneapolis St Paul
From R31 102

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Denver Intl, with prices starting at R1 786. Explore other affordable destinations below.

Denver Intl
Denver Intl
From R1 786
Minneapolis St Paul
Minneapolis St Paul
From R31 102

Airline reviews for flights from Des Moines

Get insights into the airlines that provide service from Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Des Moines. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Get a feel of what it's like to fly with British Airways from Des Moines by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
British Airways
6,7
Okay
7 515 reviews
Check prices

Food

6,3

Overall

6,7

Boarding

6,9

Entertainment

6,4

Crew

7,6

Comfort

6,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Aug 2025

IAD - LHR

The plane had to load and unload passengers not through a jet way but out on the tarmac at Heathrow. The steps were steep. We weren't expecting to have to carry our luggage up and down stairs.
British Airways
6,7
Okay
7 515 reviews
British Airways
6,7
Okay
7 515 reviews
Check prices

Food

6,3

Overall

6,7

Boarding

6,9

Entertainment

6,4

Crew

7,6

Comfort

6,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Aug 2025

IAD - LHR

The plane had to load and unload passengers not through a jet way but out on the tarmac at Heathrow. The steps were steep. We weren't expecting to have to carry our luggage up and down stairs.

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 13 November 2025.

  • What are the most popular destinations to fly to from Des Moines?

    The most selected flight destinations from Des Moines for the current month are Denver, Cancún, Dallas/Fort Worth Airport. While Denver, Cancún, Nashville are the top choices made by travellers year-round.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as R1 786 to Denver (prices may vary depending on the airline and departure time). On average, users have booked flights for R16 667 to fly from Des Moines.

  • How does Cheapflights help users find flights from Des Moines?

    Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Des Moines?

Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Des Moines with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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