R4 206+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — JNB
Jun 9 — Jun 161
1 adult
1 adult, Economy, 0 bags

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 May 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 31/10

9:37-8:20

2 stops39h 43m

Johannesburg OR Tambo

Wed 18/11

9:50-12:53

2 stops35h 03m

R23 813

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 11/9

7:34-9:00

2 stops42h 26m

Johannesburg OR Tambo

Sun 20/9

20:55-23:28

2 stops33h 33m

R25 237

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/9

10:26-4:00

2 stops34h 34m

Johannesburg OR Tambo

Mon 7/9

20:55-0:16

2 stops34h 21m

R25 974

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 11/9

20:30-13:25

2 stops33h 55m

Johannesburg OR Tambo

Sun 20/9

14:30-17:02

3 stops33h 32m

R26 907

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 2/11

8:00-18:35

3 stops26h 35m

Johannesburg OR Tambo

Mon 16/11

22:00-23:39

2 stops33h 39m

R29 787

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 16/9

14:15-19:40

1 stop22h 25m

Johannesburg OR Tambo

Sun 4/10

21:55-20:52

2 stops53h 57m

R30 016

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 21/9

11:04-19:40

1 stop25h 36m

Johannesburg OR Tambo

Sat 3/10

23:15-20:45

2 stops52h 30m

R30 376

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 16/9

14:15-19:40

1 stop22h 25m

Johannesburg OR Tambo

Sat 3/10

23:15-22:26

2 stops30h 11m

R30 376

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 20/9

11:04-19:40

1 stop25h 36m

Johannesburg OR Tambo

Tue 6/10

23:15-17:42

2 stops49h 27m

R30 376
Fastest return journey

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 11/9

16:15-19:40

1 stop20h 25m

Johannesburg OR Tambo

Sun 20/9

21:55-22:26

1 stop31h 31m

R30 605

Flights are sorted by cheapest return flights first.

Deals found on 6/5

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Des Moines

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Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 May 2026.

  • What are the most popular destinations to fly to from Des Moines?

    The most selected flight destinations from Des Moines for the current month are Las Vegas, Denver, Los Angeles. While Las Vegas, Denver, Los Angeles are the top choices made by travellers year-round.

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    Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

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How does Cheapflights help users find flights from Des Moines?

Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Des Moines with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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