R2 224+ Flights from Des Moines | Cheapflights

Find flights from Des Moines

Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 9 July 2025.

Mon 8/1212:43DSM - JNB

2 stops34h 52mBritish Airways

Mon 12/122:00JNB - DSM

2 stops31h 57mBritish Airways

Deal found 8/7R24 124

Tue 19/815:25DSM - JNB

2 stops34h 10mLufthansa

Thu 28/819:00JNB - DSM

2 stops29h 14mLufthansa

Deal found 8/7R25 885

Sat 23/811:23DSM - JNB

2 stops26h 57mKLM

Sat 30/823:15JNB - DSM

2 stops30h 28mKLM

Deal found 9/7R26 490

Sat 23/817:12DSM - JNB

1 stop19h 28mDelta

Sat 30/823:15JNB - DSM

2 stops30h 28mDelta

Deal found 9/7R26 899

Tue 19/818:13DSM - JNB

2 stops32h 22mQatar Airways

Thu 28/813:55JNB - DSM

2 stops32h 06mQatar Airways

Deal found 7/7R27 557

Thu 21/818:15DSM - JNB

2 stops31h 20mMultiple Airlines

Thu 28/819:35JNB - DSM

2 stops28h 39mMultiple Airlines

Deal found 7/7R28 660

Tue 19/811:35DSM - JNB

3 stops23h 10mUnited Airlines

Thu 28/819:00JNB - DSM

3 stops33h 45mUnited Airlines

Deal found 7/7R29 728

Thu 21/813:10DSM - JNB

3 stops37h 10mAir Canada

Thu 28/819:35JNB - DSM

3 stops33h 10mAir Canada

Deal found 6/7R31 418

Best flights from Des Moines
Discover carefully curated flight deals from Des Moines that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 9 July 2025.

Mon 8/1212:43DSM - JNB

2 stops34h 52mBritish Airways

Mon 12/122:00JNB - DSM

2 stops31h 57mBritish Airways

Deal found 8/7R24 124

Tue 19/815:25DSM - JNB

2 stops34h 10mLufthansa

Thu 28/819:00JNB - DSM

2 stops29h 14mLufthansa

Deal found 8/7R25 885

Sat 23/811:23DSM - JNB

2 stops26h 57mKLM

Sat 30/823:15JNB - DSM

2 stops30h 28mKLM

Deal found 9/7R26 490

Sat 23/817:12DSM - JNB

1 stop19h 28mDelta

Sat 30/823:15JNB - DSM

2 stops30h 28mDelta

Deal found 9/7R26 899

Tue 19/818:13DSM - JNB

2 stops32h 22mQatar Airways

Thu 28/813:55JNB - DSM

2 stops32h 06mQatar Airways

Deal found 7/7R27 557

Thu 21/818:15DSM - JNB

2 stops31h 20mMultiple Airlines

Thu 28/819:35JNB - DSM

2 stops28h 39mMultiple Airlines

Deal found 7/7R28 660

Tue 19/811:35DSM - JNB

3 stops23h 10mUnited Airlines

Thu 28/819:00JNB - DSM

3 stops33h 45mUnited Airlines

Deal found 7/7R29 728

Thu 21/813:10DSM - JNB

3 stops37h 10mAir Canada

Thu 28/819:35JNB - DSM

3 stops33h 10mAir Canada

Deal found 6/7R31 418

One-way flights from Des Moines
Search for one-way flight options from Des Moines. Find affordable one-way fares based on user searches. Data last updated 9 July 2025.

Thu 31/719:32DSM - JNB

2 stops37h 38mQatar Airways

Deal found 8/7R13 770

Thu 31/718:32DSM - JNB

3 stops59h 33mMultiple Airlines

Deal found 8/7R20 459

Thu 31/75:30DSM - JNB

1 stop31h 10mDelta

Deal found 8/7R30 493

International flights from Des Moines
Find cheap international flights from Des Moines based on historic user searches and pricing. Information updated on 9 July 2025.

Wed 20/810:58DSM - AMS

1 stop12h 57mKLM

Wed 27/810:55AMS - DSM

1 stop12h 50mKLM

Deal found 8/7R12 969

Wed 20/811:23DSM - AMS

1 stop11h 37mVirgin Atlantic

Wed 27/810:55AMS - DSM

2 stops17h 04mVirgin Atlantic

Deal found 7/7R13 201

Thu 21/88:00DSM - AMS

1 stop18h 20mUnited Airlines

Thu 28/812:15AMS - DSM

2 stops32h 55mUnited Airlines

Deal found 7/7R13 716

Fri 22/815:21DSM - AMS

2 stops15h 09mAmerican Airlines

Fri 29/810:00AMS - DSM

1 stop18h 45mAmerican Airlines

Deal found 7/7R13 948

Wed 20/811:23DSM - AMS

2 stops19h 47mScandinavian Airlines

Wed 27/86:55AMS - DSM

3 stops22h 48mScandinavian Airlines

Deal found 8/7R15 407

Mon 22/97:00DSM - AMS

2 stops16h 00mDelta

Sun 5/109:20AMS - DSM

2 stops18h 41mDelta

Deal found 7/7R15 691

Mon 3/1118:30DSM - HKT

2 stops38h 10mDelta

Tue 18/1123:20HKT - DSM

2 stops36h 03mDelta

Deal found 7/7R17 417

Mon 29/918:12DSM - BOM

2 stops27h 23mQatar Airways

Fri 3/104:20BOM - DSM

2 stops24h 39mQatar Airways

Deal found 6/7R19 463

Fri 22/811:35DSM - AMS

3 stops16h 00mAir Canada

Fri 29/814:45AMS - DSM

3 stops26h 54mAir Canada

Deal found 7/7R19 587

Thu 21/89:07DSM - BOM

2 stops30h 18mMultiple Airlines

Thu 28/811:10BOM - DSM

2 stops38h 11mMultiple Airlines

Deal found 6/7R19 943

Thu 21/813:10DSM - BOM

2 stops24h 10mLufthansa

Wed 27/81:30BOM - DSM

2 stops30h 45mLufthansa

Deal found 7/7R20 690

Thu 21/813:10DSM - DXB

2 stops21h 35mAir Canada

Wed 27/81:25DXB - DSM

2 stops31h 16mAir Canada

Deal found 7/7R21 704

Find flights from Des Moines within your budget

Fly to

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 8/12

12:43-7:35

2 stops34h 52m

Johannesburg OR Tambo

Mon 12/1

22:00-21:57

2 stops31h 57m

R24 124

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 19/8

15:25-8:35

2 stops34h 10m

Johannesburg OR Tambo

Thu 28/8

19:00-17:14

2 stops29h 14m

R25 885

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 23/8

11:23-21:20

2 stops26h 57m

Johannesburg OR Tambo

Sat 30/8

23:15-22:43

2 stops30h 28m

R26 490

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 23/8

17:12-19:40

1 stop19h 28m

Johannesburg OR Tambo

Sat 30/8

23:15-22:43

2 stops30h 28m

R26 899

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 19/8

18:13-9:35

2 stops32h 22m

Johannesburg OR Tambo

Thu 28/8

13:55-15:01

2 stops32h 06m

R27 557

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 21/8

18:15-8:35

2 stops31h 20m

Johannesburg OR Tambo

Thu 28/8

19:35-17:14

2 stops28h 39m

R28 660

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 19/8

11:35-17:45

3 stops23h 10m

Johannesburg OR Tambo

Thu 28/8

19:00-21:45

3 stops33h 45m

R29 728

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 21/8

13:10-9:20

3 stops37h 10m

Johannesburg OR Tambo

Thu 28/8

19:35-21:45

3 stops33h 10m

R31 418

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 31/7

19:32-16:10

2 stops37h 38m

R13 770

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 31/7

18:32-13:05

3 stops59h 33m

R20 459

Flights are sorted by cheapest return flights first.

Deals found on 8/7

Showing 1-10 of 11 results

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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines?

Currently, January is the cheapest month in which you can book a flight from Des Moines (average of R20 139). Flying from Des Moines in April will prove the most costly (average of R27 700). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Des Moines?

When flying from Des Moines check dates and pricing for the following: British Airways. As it departs for the following popular destinations: Johannesburg.

British Airways

British Airways

Airline reviews for flights from Des Moines

Get a feel of what it's like to fly with Delta, KLM, andQatar Airways from Des Moines by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

8,0

Very Good

Reviews

1 / 20

10,0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

8,0

Very Good

8,0

Very Good

Reviews

1 / 20

10,0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

7,8

Good

8,0

Very Good

Reviews

1 / 20

10,0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

7,4

Good

8,0

Very Good

Reviews

1 / 20

10,0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7,4

Good

8,0

Very Good

Reviews

1 / 20

10,0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

7,1

Good

8,0

Very Good

Reviews

1 / 20

10,0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

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Related info for your journey

What are the most popular destinations to fly to from Des Moines?
The most selected flight destinations from Des Moines for the current month are Denver, Nashville, Cancún. While Denver, Cancún, Nashville are the top choices made by travellers year-round.
What is the cheapest month to fly from Des Moines?
January is currently the cheapest month to fly from Des Moines. At this moment in time April is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.
How does Cheapflights help users find flights from Des Moines?
Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.
Why should you use Cheapflights to find cheap flight tickets from Des Moines?
Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Des Moines with no change fees?
Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.
Can Cheapflights notify me if prices for flights from Des Moines become cheaper?
Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Des Moines?

Cheapflights helps you search for flights from Des Moines via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Des Moines with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Des Moines flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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