R2 724+ Cheap flights from Missouri

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — JNB
Apr 25 — May 21
1 adult
1 adult, Economy, 0 bags

Find flights from Missouri within your budget

 
Find flights departing from Missouri that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 26 March 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Thu 3/9

16:18-8:20

2 stops33h 02m

Johannesburg OR Tambo

Wed 16/9

9:50-22:24

2 stops43h 34m

R21 299

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 31/8

9:13-9:00

2 stops40h 47m

Johannesburg OR Tambo

Thu 17/9

14:45-20:19

2 stops36h 34m

R22 991

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Tue 1/9

9:13-9:00

2 stops40h 47m

Johannesburg OR Tambo

Thu 17/9

14:45-20:19

2 stops36h 34m

R22 991

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Wed 6/5

16:30-8:50

2 stops33h 20m

Johannesburg OR Tambo

Sun 10/5

14:45-23:56

2 stops40h 11m

R24 091

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sat 29/8

17:32-11:50

2 stops35h 18m

Cape Town Intl

Sun 13/9

16:35-15:38

2 stops54h 03m

R24 226

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 30/8

17:32-11:50

2 stops59h 18m

Cape Town Intl

Sun 13/9

16:35-15:38

2 stops54h 03m

R24 226

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 1/5

18:11-8:50

2 stops31h 39m

Johannesburg OR Tambo

Sat 9/5

14:45-22:19

2 stops38h 34m

R24 311

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Thu 3/9

19:12-15:20

2 stops37h 08m

Johannesburg OR Tambo

Thu 10/9

14:45-20:19

2 stops36h 34m

R25 258

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 30/8

9:45-10:15

2 stops41h 30m

Cape Town Intl

Sun 13/9

19:30-23:12

2 stops34h 42m

R25 647

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 30/8

8:35-17:10

2 stops25h 35m

Cape Town Intl

Sun 13/9

17:55-13:25

1 stop26h 30m

R26 848

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from Missouri

Have a flexible travel schedule? Discover the best time to fly from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri

Get recent, data-driven insights about flights from Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri?

Currently, May is the cheapest month in which you can book a flight from Missouri (average of R16 376). Flying from Missouri in July will prove the most costly (average of R23 939). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Missouri?

When flying from Missouri check dates and pricing for the following: KLM. As it departs for the following popular destinations: Johannesburg.

KLM
KLM
From R28 556

What is the cheapest place to fly to from Missouri?

The cheapest city to fly to from Missouri is Tampa, with prices starting at R3 897. Explore other affordable destinations below.

Tampa
Tampa
From R3 897
Orlando
Orlando
From R4 941
Dallas/Fort Worth
Dallas/Fort Worth
From R16 677
Philadelphia
Philadelphia
From R21 061

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Direct flights from USA

Book a direct flight from one of these other cities located in USA.
Direct flights from St. Louis
Direct flights from Kansas City

Related info for your journey

Access useful and relevant information related to your journey from Missouri. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 26 March 2026.

  • What is the cheapest month to fly from Missouri?

    May is currently the cheapest month to fly from Missouri. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Missouri?

    Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Missouri?

    Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Missouri with no change fees?

    Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Missouri become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri?

Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Missouri?

Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Missouri with no change fees?

Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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