R2 102+ Cheap flights from Missouri

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — JNB
Apr 1 — Apr 81
1 adult
1 adult, Economy, 0 bags

What to know about flights from Missouri

Discover essential information about flights departing from Missouri, including flight schedules, destinations, airlines operating at the Missouri airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 2 March 2026.

Good round-trip deal

R3 943 or less

Good one-way deal

R4 664 or less
Price to beat on a round-trip flight from Missouri.
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Price to beat on a one-way flight from Missouri.
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Find flights from Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Missouri
Explore the most affordable flight options available from Missouri. Find the lowest fares based on data from user searches, with prices last updated on 2 March 2026.

Sun 19/412:27
STL
-
JNB
2 stops37h 23m
Qatar Airways
Mon 27/420:40
JNB
-
STL
2 stops29h 53m
Qatar Airways
Deal found 26/2R18 635
Fri 8/58:54
STL
-
JNB
2 stops40h 56m
Qatar Airways
Fri 22/520:40
JNB
-
STL
2 stops34h 14m
Qatar Airways
Deal found 27/2R19 272
Mon 13/48:54
STL
-
JNB
2 stops40h 56m
Qatar Airways
Mon 20/414:45
JNB
-
STL
2 stops38h 34m
Qatar Airways
Deal found 27/2R19 320
Tue 14/412:27
STL
-
JNB
2 stops37h 23m
Qatar Airways
Tue 21/420:40
JNB
-
STL
2 stops34h 06m
Qatar Airways
Deal found 28/2R19 543
Tue 31/36:15
STL
-
JNB
3 stops38h 40m
Ethiopian Air
Tue 7/414:30
JNB
-
STL
3 stops28h 52m
Ethiopian Air
Deal found 1/3R20 148
Wed 1/45:00
MCI
-
JNB
2 stops44h 20m
Multiple Airlines
Sat 11/49:50
JNB
-
MCI
2 stops38h 48m
Multiple Airlines
Deal found 27/2R20 371
Tue 31/39:59
STL
-
JNB
2 stops40h 11m
Qatar Airways
Tue 7/414:55
JNB
-
STL
2 stops38h 22m
Qatar Airways
Deal found 1/3R20 769
Sun 12/48:54
STL
-
JNB
2 stops47h 56m
Qatar Airways
Sun 19/414:45
JNB
-
STL
2 stops35h 48m
Qatar Airways
Deal found 26/2R21 470
Mon 30/36:30
MCI
-
JNB
2 stops42h 50m
Multiple Airlines
Fri 10/49:50
JNB
-
MCI
2 stops36h 57m
Multiple Airlines
Deal found 26/2R22 139
Wed 15/411:45
STL
-
CPT
2 stops46h 35m
Qatar Airways
Wed 22/413:00
CPT
-
STL
2 stops40h 59m
Qatar Airways
Deal found 1/3R22 760
Thu 16/48:54
STL
-
JNB
2 stops40h 56m
Qatar Airways
Mon 20/414:45
JNB
-
STL
2 stops38h 34m
Qatar Airways
Deal found 26/2R22 871
Tue 14/411:45
STL
-
CPT
2 stops40h 45m
Qatar Airways
Tue 21/413:00
CPT
-
STL
2 stops35h 21m
Qatar Airways
Deal found 28/2R22 935

Find flights from Missouri within your budget

 
Find flights departing from Missouri that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 2 March 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 30/3

6:30-8:20

2 stops42h 50m

Johannesburg OR Tambo

Fri 10/4

9:50-15:47

2 stops36h 57m

R22 139

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Thu 19/3

14:19-3:55

2 stops30h 36m

Johannesburg OR Tambo

Mon 23/3

13:45-23:44

2 stops40h 59m

R23 397

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Tue 31/3

18:59-19:40

1 stop17h 41m

Johannesburg OR Tambo

Tue 7/4

23:15-23:25

2 stops31h 10m

R23 700

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 12/4

8:21-17:10

2 stops25h 49m

Cape Town Intl

Sun 19/4

20:00-10:28

1 stop21h 28m

R23 827

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Sun 19/4

6:20-19:40

2 stops30h 20m

Johannesburg OR Tambo

Mon 27/4

21:55-17:44

1 stop26h 49m

R23 907

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Tue 31/3

6:32-21:25

2 stops31h 53m

Cape Town Intl

Tue 7/4

23:45-23:58

2 stops31h 13m

R24 369

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 15/5

7:15-21:20

2 stops31h 05m

Johannesburg OR Tambo

Sat 23/5

21:55-18:00

1 stop27h 05m

R24 496

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Mon 13/4

11:42-19:40

1 stop24h 58m

Johannesburg OR Tambo

Mon 20/4

23:15-23:36

2 stops31h 21m

R24 496

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Sun 29/3

10:37-7:05

2 stops37h 28m

Cape Town Intl

Sun 5/4

20:05-15:39

1 stop26h 34m

R24 671

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Sun 29/3

17:45-15:20

1 stop38h 35m

Cape Town Intl

Sun 5/4

8:00-19:45

2 stops42h 45m

R24 703

Flights are sorted by cheapest return flights first.

Deals found on 26/2

Showing 1-10 of 39 resultsSorted by cheapest first
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Best time to book a flight from Missouri

Have a flexible travel schedule? Discover the best time to fly from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri

Get recent, data-driven insights about flights from Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri?

Currently, February is the cheapest month in which you can book a flight from Missouri (average of R15 386). Flying from Missouri in July will prove the most costly (average of R22 855). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Missouri?

When flying from Missouri check dates and pricing for the following: KLM. As it departs for the following popular destinations: Johannesburg.

KLM
KLM
From R26 884

What is the cheapest place to fly to from Missouri?

The cheapest city to fly to from Missouri is Orlando, with prices starting at R3 355. Explore other affordable destinations below.

Orlando
Orlando
From R3 355
Tampa
Tampa
From R3 669
Dallas/Fort Worth
Dallas/Fort Worth
From R15 700
Philadelphia
Philadelphia
From R19 828

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from USA

Book a direct flight from one of these other cities located in USA.
Direct flights from St. Louis
Direct flights from Kansas City

Related info for your journey

Access useful and relevant information related to your journey from Missouri. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 2 March 2026.

  • What is the cheapest month to fly from Missouri?

    February is currently the cheapest month to fly from Missouri. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Missouri?

    Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Missouri?

    Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Missouri with no change fees?

    Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Missouri become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri?

Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Missouri?

Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Missouri with no change fees?

Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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