R2 494+ Cheap flights from Missouri

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — JNB
Mar 27 — Apr 31
1 adult
1 adult, Economy, 0 bags

What to know about flights from Missouri

Discover essential information about flights departing from Missouri, including flight schedules, destinations, airlines operating at the Missouri airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 25 February 2026.

Good round-trip deal

R3 958 or less

Good one-way deal

R4 682 or less
Price to beat on a round-trip flight from Missouri.
Search Deals
Price to beat on a one-way flight from Missouri.
Search Deals

Find flights from Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Missouri
Explore the most affordable flight options available from Missouri. Find the lowest fares based on data from user searches, with prices last updated on 25 February 2026.

Tue 31/39:59
STL
-
JNB
2 stops46h 51m
Qatar Airways
Tue 7/414:55
JNB
-
STL
2 stops35h 38m
Qatar Airways
Deal found 23/2R18 674
Sun 19/412:27
STL
-
JNB
2 stops37h 23m
Qatar Airways
Mon 27/420:40
JNB
-
STL
2 stops32h 39m
Qatar Airways
Deal found 24/2R18 706
Wed 8/47:05
STL
-
JNB
2 stops37h 55m
Qatar Airways
Wed 15/414:45
JNB
-
STL
2 stops38h 32m
Qatar Airways
Deal found 22/2R18 866
Tue 21/414:33
STL
-
JNB
2 stops35h 17m
Qatar Airways
Tue 28/414:45
JNB
-
STL
2 stops35h 48m
Qatar Airways
Deal found 21/2R19 009
Sat 18/414:33
STL
-
JNB
2 stops35h 17m
Qatar Airways
Mon 27/420:40
JNB
-
STL
2 stops34h 06m
Qatar Airways
Deal found 21/2R19 345
Mon 20/47:05
MCI
-
JNB
2 stops42h 15m
Multiple Airlines
Wed 29/49:50
JNB
-
MCI
2 stops36h 57m
Multiple Airlines
Deal found 21/2R19 393
Mon 20/414:33
STL
-
JNB
2 stops35h 17m
Qatar Airways
Mon 27/420:40
JNB
-
STL
2 stops29h 53m
Qatar Airways
Deal found 21/2R19 905
Fri 24/77:00
MCI
-
JNB
2 stops42h 20m
Etihad Airways
Sun 9/89:50
JNB
-
MCI
2 stops38h 50m
Etihad Airways
Deal found 24/2R20 288
Fri 8/512:25
STL
-
JNB
2 stops37h 25m
Qatar Airways
Fri 22/520:40
JNB
-
STL
2 stops34h 14m
Qatar Airways
Deal found 21/2R20 288
Sun 16/88:35
STL
-
JNB
2 stops36h 25m
Qatar Airways
Wed 2/920:55
JNB
-
STL
2 stops30h 24m
Qatar Airways
Deal found 24/2R20 960
Fri 10/48:54
STL
-
JNB
2 stops36h 06m
Qatar Airways
Thu 23/414:45
JNB
-
STL
2 stops38h 32m
Qatar Airways
Deal found 23/2R21 488
Mon 30/36:28
MCI
-
JNB
2 stops38h 32m
Qatar Airways
Fri 10/412:40
JNB
-
MCI
2 stops32h 03m
Qatar Airways
Deal found 24/2R22 143

Find flights from Missouri within your budget

 
Find flights departing from Missouri that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 25 February 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Tue 31/3

9:59-15:50

2 stops46h 51m

Johannesburg OR Tambo

Tue 7/4

12:40-22:17

2 stops40h 37m

R19 041

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 20/4

7:05-8:20

2 stops42h 15m

Johannesburg OR Tambo

Wed 29/4

9:50-15:47

2 stops36h 57m

R19 393

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 30/3

6:30-8:20

2 stops42h 50m

Johannesburg OR Tambo

Fri 10/4

9:50-17:26

2 stops38h 36m

R22 223

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Mon 20/4

14:33-11:30

2 stops37h 57m

Cape Town Intl

Wed 29/4

13:00-13:43

2 stops31h 43m

R23 710

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 8/3

16:21-19:15

1 stop19h 54m

Cape Town Intl

Sat 14/3

23:45-23:58

2 stops31h 13m

R23 774

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 10/4

16:21-19:40

1 stop20h 19m

Johannesburg OR Tambo

Thu 23/4

21:55-15:32

1 stop24h 37m

R23 918

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 8/5

13:27-19:40

1 stop23h 13m

Johannesburg OR Tambo

Fri 22/5

21:55-18:00

1 stop27h 05m

R23 918

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 15/5

19:01-19:40

1 stop17h 39m

Johannesburg OR Tambo

Sat 23/5

21:55-18:00

1 stop27h 05m

R23 918

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 8/3

16:50-11:00

1 stop35h 10m

Cape Town Intl

Sat 14/3

9:30-15:29

2 stops60h 59m

R23 998

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Sun 19/4

6:20-19:40

2 stops30h 20m

Johannesburg OR Tambo

Mon 27/4

21:55-17:44

1 stop26h 49m

R23 998

Flights are sorted by cheapest return flights first.

Deals found on 23/2

Showing 1-10 of 44 results
1
2
3
...
5

Best time to book a flight from Missouri

Have a flexible travel schedule? Discover the best time to fly from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri

Get recent, data-driven insights about flights from Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri?

Currently, February is the cheapest month in which you can book a flight from Missouri (average of R15 444). Flying from Missouri in July will prove the most costly (average of R22 942). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Missouri?

When flying from Missouri check dates and pricing for the following: KLM. As it departs for the following popular destinations: Johannesburg.

KLM
KLM
From R26 986

What is the cheapest place to fly to from Missouri?

The cheapest city to fly to from Missouri is Orlando, with prices starting at R3 368. Explore other affordable destinations below.

Orlando
Orlando
From R3 368
Tampa
Tampa
From R3 683
Dallas/Fort Worth
Dallas/Fort Worth
From R15 760
Philadelphia
Philadelphia
From R19 904

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from USA

Book a direct flight from one of these other cities located in USA.
Direct flights from St. Louis
Direct flights from Kansas City

Related info for your journey

Access useful and relevant information related to your journey from Missouri. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 25 February 2026.

  • What is the cheapest month to fly from Missouri?

    February is currently the cheapest month to fly from Missouri. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Missouri?

    Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Missouri?

    Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Missouri with no change fees?

    Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Missouri become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri?

Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Missouri?

Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Missouri with no change fees?

Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.