R1 993+ Cheap flights from Missouri

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — JNB
Dec 14 — Dec 211
1 adult
1 adult, Economy, 0 bags

What to know about flights from Missouri

Discover essential information about flights departing from Missouri, including flight schedules, destinations, airlines operating at the Missouri airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 14 November 2025.

Good round-trip deal

R4 217 or less

Good one-way deal

R4 249 or less
Price to beat on a round-trip flight from Missouri.
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Price to beat on a one-way flight from Missouri.
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Find flights from Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Missouri
Explore the most affordable flight options available from Missouri. Find the lowest fares based on data from user searches, with prices last updated on 14 November 2025.

Wed 21/113:00STL - CPT
1 stop22h 15mDelta
Sun 1/221:30CPT - STL
1 stop28h 20mDelta
Deal found 13/11R20 303
Mon 16/218:50STL - JNB
2 stops29h 50mQatar Airways
Mon 2/313:45JNB - STL
2 stops35h 20mQatar Airways
Deal found 12/11R21 001
Thu 5/316:06MCI - JNB
2 stops31h 29mAmerican Airlines
Mon 9/319:35JNB - MCI
2 stops31h 40mAmerican Airlines
Deal found 13/11R21 018
Thu 30/47:00MCI - CPT
2 stops44h 50mQatar Airways
Mon 1/613:00CPT - MCI
2 stops41h 38mQatar Airways
Deal found 13/11R21 904
Wed 11/217:09MCI - CPT
1 stop18h 06mDelta
Mon 23/221:30CPT - MCI
1 stop30h 32mDelta
Deal found 13/11R22 006
Thu 5/314:19STL - JNB
2 stops33h 16mAmerican Airlines
Mon 9/319:35JNB - STL
2 stops29h 40mAmerican Airlines
Deal found 13/11R22 040
Wed 11/28:00MCI - CPT
2 stops26h 00mUnited Airlines
Mon 23/220:50CPT - MCI
2 stops25h 20mUnited Airlines
Deal found 12/11R22 074
Mon 30/320:03MCI - JNB
2 stops30h 57mQatar Airways
Fri 10/413:55JNB - MCI
2 stops33h 06mQatar Airways
Deal found 12/11R22 074
Tue 25/1117:35MCI - JNB
2 stops30h 00mAmerican Airlines
Tue 9/1222:00JNB - MCI
2 stops31h 29mAmerican Airlines
Deal found 13/11R22 313
Fri 3/412:01STL - JNB
2 stops45h 09mQatar Airways
Fri 10/413:55JNB - STL
2 stops33h 16mQatar Airways
Deal found 12/11R22 738
Fri 1/514:55STL - CPT
2 stops60h 55mMultiple Airlines
Fri 29/513:00CPT - STL
2 stops42h 04mMultiple Airlines
Deal found 13/11R22 977
Sat 21/318:29STL - CPT
2 stops30h 36mAmerican Airlines
Wed 25/320:35CPT - STL
2 stops32h 13mAmerican Airlines
Deal found 13/11R23 318

Find flights from Missouri within your budget

 
Find flights departing from Missouri that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 14 November 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sat 31/1

13:00-19:15

1 stop22h 15m

Cape Town Intl

Sun 8/2

21:30-17:50

1 stop28h 20m

R20 303

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Wed 21/1

13:00-19:15

1 stop22h 15m

Cape Town Intl

Sun 1/2

21:30-17:50

1 stop28h 20m

R20 303

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Wed 28/1

9:59-19:15

1 stop25h 16m

Cape Town Intl

Fri 6/2

21:30-15:58

1 stop26h 28m

R20 303

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Wed 18/2

17:55-8:40

2 stops30h 45m

Johannesburg OR Tambo

Wed 4/3

12:45-17:05

2 stops36h 20m

R21 001

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Thu 30/4

7:00-10:50

2 stops44h 50m

Cape Town Intl

Mon 1/6

13:00-23:38

2 stops41h 38m

R21 904

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Wed 11/2

13:22-19:15

1 stop21h 53m

Cape Town Intl

Mon 23/2

21:30-17:08

1 stop27h 38m

R22 006

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Wed 11/2

17:09-19:15

1 stop18h 06m

Cape Town Intl

Mon 23/2

21:30-20:02

1 stop30h 32m

R22 006

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Thu 5/3

14:19-7:35

2 stops33h 16m

Johannesburg OR Tambo

Mon 9/3

19:35-18:15

2 stops29h 40m

R22 040

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Wed 11/2

8:00-18:00

2 stops26h 00m

Cape Town Intl

Mon 23/2

20:50-14:10

2 stops25h 20m

R22 074

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 30/3

20:03-10:00

2 stops30h 57m

Johannesburg OR Tambo

Fri 10/4

13:55-16:01

2 stops33h 06m

R22 074

Flights are sorted by cheapest return flights first.

Deals found on 14/11

Showing 1-10 of 50 results
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Best time to book a flight from Missouri

Have a flexible travel schedule? Discover the best time to fly from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri

Get recent, data-driven insights about flights from Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri?

Currently, January is the cheapest month in which you can book a flight from Missouri (average of R16 419). Flying from Missouri in August will prove the most costly (average of R26 418). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Missouri?

When flying from Missouri check dates and pricing for the following: United Airlines, British Airways. As they depart for the following popular destinations: Johannesburg.

United Airlines
United Airlines
From R23 401
British Airways
British Airways
From R25 396

What is the cheapest place to fly to from Missouri?

The cheapest city to fly to from Missouri is Tampa, with prices starting at R3 923. Explore other affordable destinations below.

Tampa
Tampa
From R3 923
New York
New York
From R4 249

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Direct flights from USA

Book a direct flight from one of these other cities located in USA.
Direct flights from St. Louis
Direct flights from Kansas City

Related info for your journey

Access useful and relevant information related to your journey from Missouri. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 14 November 2025.

  • What is the cheapest month to fly from Missouri?

    January is currently the cheapest month to fly from Missouri. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Missouri?

    Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Missouri?

    Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Missouri with no change fees?

    Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Missouri become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri?

Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Missouri?

Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Missouri with no change fees?

Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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