R2 614+ Cheap flights from Missouri

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — JNB
Apr 9 — Apr 161
1 adult
1 adult, Economy, 0 bags

What to know about flights from Missouri

Discover essential information about flights departing from Missouri, including flight schedules, destinations, airlines operating at the Missouri airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 10 March 2026.

Good round-trip deal

R4 122 or less

Good one-way deal

R4 875 or less
Price to beat on a round-trip flight from Missouri.
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Price to beat on a one-way flight from Missouri.
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Find flights from Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Missouri
Explore the most affordable flight options available from Missouri. Find the lowest fares based on data from user searches, with prices last updated on 10 March 2026.

Tue 14/416:30
STL
-
JNB
2 stops33h 20m
Qatar Airways
Tue 21/420:40
JNB
-
STL
2 stops29h 53m
Qatar Airways
Deal found 9/3R19 229
Fri 1/520:30
STL
-
JNB
2 stops33h 35m
Ethiopian Air
Tue 12/514:30
JNB
-
STL
3 stops37h 43m
Ethiopian Air
Deal found 5/3R19 378
Wed 22/414:33
STL
-
JNB
2 stops42h 17m
Qatar Airways
Wed 29/420:40
JNB
-
STL
2 stops32h 37m
Qatar Airways
Deal found 8/3R19 478
Sun 19/412:27
STL
-
JNB
2 stops37h 23m
Qatar Airways
Mon 27/420:40
JNB
-
STL
2 stops32h 39m
Qatar Airways
Deal found 5/3R19 495
Thu 23/47:05
STL
-
JNB
2 stops49h 45m
Qatar Airways
Thu 30/414:45
JNB
-
STL
2 stops35h 48m
Qatar Airways
Deal found 9/3R19 578
Mon 30/39:17
MCI
-
JNB
2 stops35h 43m
Qatar Airways
Fri 10/412:40
JNB
-
MCI
2 stops39h 04m
Qatar Airways
Deal found 7/3R19 961
Sun 6/913:37
STL
-
JNB
2 stops31h 23m
Qatar Airways
Sun 20/920:55
JNB
-
STL
2 stops30h 08m
Qatar Airways
Deal found 6/3R20 111
Mon 31/89:13
MCI
-
JNB
2 stops35h 47m
Qatar Airways
Wed 9/920:55
JNB
-
MCI
2 stops30h 24m
Qatar Airways
Deal found 5/3R20 161
Tue 21/416:30
STL
-
JNB
2 stops33h 20m
Qatar Airways
Tue 28/414:45
JNB
-
STL
2 stops40h 01m
Qatar Airways
Deal found 7/3R20 211
Sun 19/412:27
STL
-
JNB
2 stops37h 23m
Qatar Airways
Sun 26/420:40
JNB
-
STL
2 stops32h 37m
Qatar Airways
Deal found 5/3R20 228
Thu 3/95:17
MCI
-
JNB
2 stops44h 03m
Etihad Airways
Thu 8/109:50
JNB
-
MCI
2 stops34h 28m
Etihad Airways
Deal found 7/3R21 077
Fri 8/512:27
STL
-
JNB
2 stops37h 23m
Qatar Airways
Fri 22/520:40
JNB
-
STL
2 stops34h 14m
Qatar Airways
Deal found 5/3R21 143

Find flights from Missouri within your budget

 
Find flights departing from Missouri that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 March 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Thu 9/4

11:25-8:15

2 stops37h 50m

Johannesburg OR Tambo

Wed 22/4

9:45-16:41

2 stops37h 56m

R21 193

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Mon 20/4

20:15-11:50

2 stops56h 35m

Cape Town Intl

Mon 27/4

16:35-8:25

2 stops46h 50m

R24 673

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Sun 6/9

16:52-18:30

1 stop18h 38m

Johannesburg OR Tambo

Sun 20/9

19:00-13:25

1 stop25h 25m

R25 155

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Sun 19/4

12:27-8:50

2 stops37h 23m

Johannesburg OR Tambo

Wed 22/4

20:40-22:17

2 stops32h 37m

R25 838
Fastest return journey

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sat 4/4

12:15-15:20

1 stop20h 05m

Cape Town Intl

Sun 19/4

20:00-10:28

1 stop21h 28m

R25 921

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Thu 3/9

13:30-19:40

1 stop23h 10m

Johannesburg OR Tambo

Wed 16/9

21:55-14:38

1 stop23h 43m

R26 071

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 8/5

9:15-19:40

1 stop27h 25m

Johannesburg OR Tambo

Fri 22/5

21:55-18:00

1 stop27h 05m

R26 071

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Sun 19/4

9:59-19:40

1 stop26h 41m

Johannesburg OR Tambo

Mon 27/4

21:55-21:19

1 stop30h 24m

R26 071

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Fri 8/5

19:01-17:50

1 stop39h 49m

Cape Town Intl

Sun 17/5

20:05-17:56

1 stop28h 51m

R26 154

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Tue 21/4

18:16-11:30

2 stops34h 14m

Cape Town Intl

Mon 27/4

13:00-17:18

2 stops35h 18m

R26 221

Flights are sorted by cheapest return flights first.

Deals found on 9/3

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Missouri

Have a flexible travel schedule? Discover the best time to fly from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri

Get recent, data-driven insights about flights from Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri?

Currently, May is the cheapest month in which you can book a flight from Missouri (average of R16 115). Flying from Missouri in July will prove the most costly (average of R23 557). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Missouri?

When flying from Missouri check dates and pricing for the following: KLM. As it departs for the following popular destinations: Johannesburg.

KLM
KLM
From R28 101

What is the cheapest place to fly to from Missouri?

The cheapest city to fly to from Missouri is Orlando, with prices starting at R3 507. Explore other affordable destinations below.

Orlando
Orlando
From R3 507
Tampa
Tampa
From R3 835
Dallas/Fort Worth
Dallas/Fort Worth
From R16 411
Philadelphia
Philadelphia
From R20 726

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Direct flights from USA

Book a direct flight from one of these other cities located in USA.
Direct flights from St. Louis
Direct flights from Kansas City

Related info for your journey

Access useful and relevant information related to your journey from Missouri. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 March 2026.

  • What is the cheapest month to fly from Missouri?

    May is currently the cheapest month to fly from Missouri. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Missouri?

    Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Missouri?

    Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Missouri with no change fees?

    Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Missouri become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri?

Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Missouri?

Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Missouri with no change fees?

Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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