R2 527+ Cheap flights from Missouri

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — CPT
Mar 23 — Mar 301
1 adult
1 adult, Economy, 0 bags

What to know about flights from Missouri

Discover essential information about flights departing from Missouri, including flight schedules, destinations, airlines operating at the Missouri airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 21 February 2026.

Good round-trip deal

R3 986 or less

Good one-way deal

R4 016 or less
Price to beat on a round-trip flight from Missouri.
Search Deals
Price to beat on a one-way flight from Missouri.
Search Deals

Find flights from Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Missouri
Explore the most affordable flight options available from Missouri. Find the lowest fares based on data from user searches, with prices last updated on 21 February 2026.

Tue 31/39:21
STL
-
JNB
2 stops46h 59m
Qatar Airways
Tue 7/414:45
JNB
-
STL
2 stops35h 48m
Qatar Airways
Deal found 17/2R18 803
Sun 19/48:54
STL
-
JNB
2 stops40h 56m
Qatar Airways
Mon 27/420:40
JNB
-
STL
2 stops29h 53m
Qatar Airways
Deal found 18/2R18 835
Wed 4/38:17
STL
-
CPT
2 stops25h 43m
United Airlines
Tue 10/320:50
CPT
-
STL
1 stop20h 22m
United Airlines
Deal found 18/2R19 237
Fri 8/58:54
STL
-
JNB
2 stops40h 56m
Qatar Airways
Fri 22/520:40
JNB
-
STL
2 stops34h 14m
Qatar Airways
Deal found 20/2R19 785
Wed 11/313:14
STL
-
CPT
2 stops20h 46m
United Airlines
Tue 24/39:30
CPT
-
STL
2 stops60h 59m
United Airlines
Deal found 18/2R21 813
Sun 5/410:33
STL
-
JNB
2 stops46h 17m
Qatar Airways
Sun 12/412:40
JNB
-
STL
2 stops40h 37m
Qatar Airways
Deal found 20/2R21 974
Mon 30/316:14
MCI
-
JNB
2 stops28h 46m
Qatar Airways
Fri 10/412:40
JNB
-
MCI
2 stops32h 03m
Qatar Airways
Deal found 17/2R22 296
Mon 30/35:00
MCI
-
JNB
2 stops44h 20m
Multiple Airlines
Fri 10/49:50
JNB
-
MCI
2 stops36h 57m
Multiple Airlines
Deal found 20/2R22 377
Mon 16/318:50
STL
-
JNB
2 stops38h 10m
Qatar Airways
Tue 24/312:45
JNB
-
STL
2 stops41h 59m
Qatar Airways
Deal found 17/2R22 377
Tue 7/414:33
STL
-
JNB
2 stops42h 17m
Qatar Airways
Tue 14/414:45
JNB
-
STL
2 stops40h 01m
Qatar Airways
Deal found 20/2R22 811
Sun 8/311:25
STL
-
CPT
2 stops22h 35m
United Airlines
Sat 14/39:30
CPT
-
STL
2 stops60h 59m
United Airlines
Deal found 19/2R23 423
Wed 11/311:33
MCI
-
CPT
2 stops22h 27m
United Airlines
Tue 24/39:30
CPT
-
MCI
2 stops60h 39m
United Airlines
Deal found 18/2R23 568

Find flights from Missouri within your budget

 
Find flights departing from Missouri that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 21 February 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Thu 5/3

8:17-16:10

2 stops23h 53m

Cape Town Intl

Tue 10/3

20:50-10:12

1 stop20h 22m

R19 237

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Wed 4/3

8:17-18:00

2 stops25h 43m

Cape Town Intl

Tue 10/3

20:50-10:12

1 stop20h 22m

R19 237

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 8/5

8:54-8:50

2 stops40h 56m

Johannesburg OR Tambo

Fri 22/5

20:40-23:54

2 stops34h 14m

R19 785

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Wed 11/3

13:14-17:00

2 stops20h 46m

Cape Town Intl

Tue 24/3

9:30-15:29

2 stops60h 59m

R21 813

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 30/3

16:14-4:00

2 stops28h 46m

Johannesburg OR Tambo

Fri 10/4

12:40-13:43

2 stops32h 03m

R22 296

Kansas CityJohannesburg

MCI - JNB

MCIJNB

Kansas City

Mon 30/3

5:00-8:20

2 stops44h 20m

Johannesburg OR Tambo

Fri 10/4

9:50-17:26

2 stops38h 36m

R22 377

St. LouisCape Town

STL - CPT

STLCPT

Lambert-St Louis

Sun 8/3

13:14-17:00

2 stops20h 46m

Cape Town Intl

Sat 14/3

9:30-15:29

2 stops60h 59m

R23 423

Kansas CityCape Town

MCI - CPT

MCICPT

Kansas City

Wed 11/3

11:33-17:00

2 stops22h 27m

Cape Town Intl

Tue 24/3

9:30-15:09

2 stops60h 39m

R23 568

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Sun 19/4

9:59-19:40

1 stop26h 41m

Johannesburg OR Tambo

Mon 27/4

21:55-21:19

1 stop30h 24m

R24 083

St. LouisJohannesburg

STL - JNB

STLJNB

Lambert-St Louis

Fri 8/5

10:43-19:40

1 stop25h 57m

Johannesburg OR Tambo

Fri 22/5

21:55-23:59

1 stop33h 04m

R24 180

Flights are sorted by cheapest return flights first.

Deals found on 18/2

Showing 1-10 of 47 results
1
2
3
...
5

Best time to book a flight from Missouri

Have a flexible travel schedule? Discover the best time to fly from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri

Get recent, data-driven insights about flights from Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri?

Currently, March is the cheapest month in which you can book a flight from Missouri (average of R16 114). Flying from Missouri in July will prove the most costly (average of R27 576). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Missouri?

When flying from Missouri check dates and pricing for the following: KLM. As it departs for the following popular destinations: Cape Town.

Turkish Airlines
Turkish Airlines
From R11 512
KLM
KLM
From R11 826

What is the cheapest place to fly to from Missouri?

The cheapest city to fly to from Missouri is Tampa, with prices starting at R3 708. Explore other affordable destinations below.

Tampa
Tampa
From R3 708
New York
New York
From R4 016
Dallas/Fort Worth
Dallas/Fort Worth
From R15 869
Philadelphia
Philadelphia
From R20 041

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from USA

Book a direct flight from one of these other cities located in USA.
Direct flights from St. Louis
Direct flights from Kansas City

Related info for your journey

Access useful and relevant information related to your journey from Missouri. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 February 2026.

  • What is the cheapest month to fly from Missouri?

    March is currently the cheapest month to fly from Missouri. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Missouri?

    Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Missouri?

    Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Missouri with no change fees?

    Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Missouri become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri?

Deals for flights from Missouri are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Missouri?

Cheapflights simply makes it quick and affordable to book flights from Missouri by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Missouri with no change fees?

Need flexible booking options for your flight from Missouri ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.