R12 826+ Cheap flights from Panama
This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
What to know about flights from Panama
Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 6 July 2025.
Good round-trip deal | R17 799 or less |
|---|---|
Good one-way deal | R1 353 or less |
Find flights from Panama
Cheapest flights from PanamaExplore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 6 July 2025.
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 6 July 2025.
Find flights from Panama within your budget
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 6 July 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches
Fly to
Route
Depart
Return
Price
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Fri 12/9
8:03-17:45
2 stops26h 42m
Johannesburg OR Tambo
Mon 22/9
19:00-6:13
2 stops42h 13m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Thu 31/7
3:20-14:40
3 stops28h 20m
Johannesburg OR Tambo
Thu 7/8
0:45-0:45
3 stops31h 00m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Fri 12/9
18:50-21:35
1 stop43h 45m
Johannesburg OR Tambo
Mon 22/9
23:15-16:50
1 stop24h 35m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Fri 12/9
15:31-9:25
3 stops34h 54m
Johannesburg OR Tambo
Mon 22/9
19:25-12:55
2 stops48h 30m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Tue 7/10
20:00-11:50
1 stop32h 50m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Mon 6/10
3:25-6:40
2 stops20h 15m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Tue 7/10
15:53-11:35
2 stops36h 42m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Tue 7/10
15:19-11:00
3 stops36h 41m
Best time to book a flight from Panama
Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Travel insights for flights from Panama
Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.
What is the cheapest month to book a flight from Panama?
Currently, October is the cheapest month in which you can book a flight from Panama (average of R18 220). Flying from Panama in August will prove the most costly (average of R29 482). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.
Which airlines fly from Panama?
When flying from Panama check dates and pricing for the following: United Airlines. As it departs for the following popular destinations: Johannesburg.
What is the cheapest place to fly to from Panama?
The cheapest city to fly to from Panama is Bogotá El Dorado, with prices starting at R1 353. Explore other affordable destinations below.
Airline reviews for flights from Panama
Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Get a feel of what it's like to fly with KLM, United Airlines, andAmerican Airlines from Panama by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
Overall
Comfort
Food
Boarding
Crew
Reviews
Anonymous,Jun 2025
AMS - BOS
Entertainment
Overall
Comfort
Food
Boarding
Crew
Reviews
Anonymous,Jun 2025
AMS - BOS
Entertainment
Overall
Comfort
Food
Boarding
Crew
Reviews
Anonymous,Jun 2025
AMS - BOS
Entertainment
Overall
Comfort
Food
Boarding
Crew
Reviews
Anonymous,Jun 2025
AMS - BOS
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Direct flights from Central America
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Related info for your journey
Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 6 July 2025.
Fly with Cheapflights
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How does Cheapflights help users find flights from Panama?
Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.
Why should you use Cheapflights to find cheap flight tickets from Panama?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.
Can Cheapflights find flights from Panama with no change fees?
Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.
Can Cheapflights notify me if prices for flights from Panama become cheaper?
Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!