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Cheap flights from South Africa to Missouri from R10 660

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/3. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — STL
Feb 22 — Mar 11
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Missouri
Explore the most affordable flight options available from South Africa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 January 2026.

Thu 12/220:50
CPT
-
STL
2 stops23h 31m
United Airlines
Tue 8/1213:27
STL
-
CPT
2 stops20h 33m
United Airlines
Deal found 21/1R16 427
Thu 5/219:35
JNB
-
STL
2 stops47h 28m
British Airways
Mon 9/214:54
STL
-
JNB
2 stops35h 31m
British Airways
Deal found 20/1R16 913
Thu 12/323:59
JNB
-
STL
2 stops30h 59m
KLM
Thu 19/312:28
STL
-
JNB
2 stops26h 37m
KLM
Deal found 21/1R17 221
Sat 7/322:00
JNB
-
STL
2 stops32h 25m
Delta
Sat 14/310:50
STL
-
JNB
2 stops25h 10m
Delta
Deal found 21/1R17 562
Thu 12/310:10
JNB
-
STL
2 stops35h 45m
Lufthansa
Thu 19/311:28
STL
-
JNB
1 stop24h 07m
Lufthansa
Deal found 21/1R19 003
Sun 8/319:45
JNB
-
MCI
2 stops31h 56m
United Airlines
Sun 15/38:00
MCI
-
JNB
2 stops42h 30m
United Airlines
Deal found 21/1R19 716
Sat 7/321:55
JNB
-
STL
1 stop30h 11m
Virgin Atlantic
Sat 14/317:00
STL
-
JNB
1 stop19h 00m
Virgin Atlantic
Deal found 21/1R20 721
Wed 28/120:35
CPT
-
STL
2 stops51h 39m
British Airways
Sun 1/214:54
STL
-
CPT
2 stops57h 11m
British Airways
Deal found 20/1R23 248
Wed 28/119:05
JNB
-
MCI
2 stops34h 54m
Turkish Airlines
Sun 1/28:00
MCI
-
JNB
2 stops42h 50m
Turkish Airlines
Deal found 21/1R23 750
Fri 20/39:50
JNB
-
STL
2 stops55h 49m
Etihad Airways
Fri 27/39:15
STL
-
JNB
2 stops40h 05m
Etihad Airways
Deal found 21/1R23 928
Fri 20/321:55
JNB
-
STL
1 stop21h 12m
Multiple Airlines
Fri 27/310:12
STL
-
JNB
1 stop25h 48m
Multiple Airlines
Deal found 21/1R25 289
Thu 22/113:45
JNB
-
MCI
2 stops34h 37m
Qatar Airways
Mon 26/16:06
MCI
-
JNB
2 stops37h 49m
Qatar Airways
Deal found 20/1R26 731

Find flight deals from South Africa to Missouri

Keep the following information in mind while searching for South Africa to Missouri flight deals. Data was last updated 23 January 2026.

Round-trip from

R16 427

One-way from

R10 660

Popular in

April

Cheapest in

October

Average price

R18 922
United Airlines
  • United Airlines
  • 12/2-8/12
  • 4 total stops
  • 44h 04m total
  • South Africa to Missouri
Search Deals
28/3
  • 28/3
  • 3 total stops
  • 54h 20m total
  • South Africa to Missouri
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (R27 965 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (R6 688 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 23 January 2026.
Use the filters below to find and compare flights from South Africa to Missouri that are best for you.

Fly from

South Africa

Fly to

Missouri

Route

Depart

Return

Price

Cape TownSt. Louis

CPT - STL

CPTSTL

Cape Town Intl

Thu 12/2

20:50-10:58

1 stop22h 08m

Lambert-St Louis

Tue 8/12

13:27-18:00

2 stops20h 33m

R16 427

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Thu 5/2

19:35-11:03

2 stops47h 28m

Lambert-St Louis

Mon 9/2

14:54-10:25

2 stops35h 31m

R16 913

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Thu 12/3

23:59-23:58

2 stops30h 59m

Lambert-St Louis

Thu 19/3

12:28-22:05

2 stops26h 37m

R17 221

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Sat 7/3

22:00-20:06

2 stops30h 06m

Lambert-St Louis

Sat 14/3

17:00-19:00

1 stop19h 00m

R17 562

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Thu 12/3

10:10-14:55

2 stops35h 45m

Lambert-St Louis

Thu 19/3

11:28-18:35

1 stop24h 07m

R19 003

JohannesburgKansas City

JNB - MCI

JNBMCI

Johannesburg OR Tambo

Sun 8/3

19:45-20:41

2 stops31h 56m

Kansas City

Sun 15/3

8:00-9:30

2 stops42h 30m

R19 716

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Fri 20/3

9:50-10:39

2 stops55h 49m

Lambert-St Louis

Fri 27/3

9:15-8:20

2 stops40h 05m

R23 928

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Fri 20/3

21:55-12:07

1 stop21h 12m

Lambert-St Louis

Fri 27/3

10:12-19:00

1 stop25h 48m

R25 289

JohannesburgSt. Louis

JNB - STL

JNBSTL

Johannesburg OR Tambo

Thu 12/3

20:15-22:59

3 stops33h 44m

Lambert-St Louis

Thu 19/3

16:05-10:30

2 stops35h 25m

R27 088

JohannesburgKansas City

JNB - MCI

JNBMCI

Johannesburg OR Tambo

Sat 28/3

17:00-16:20

3 stops54h 20m

R10 660

Flights are sorted by cheapest return flights first.

Deals found on 20/1

Showing 1-10 of 16 results
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Best time to book a flight from South Africa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Missouri

What is the cheapest month to book a flight from South Africa to Missouri?

Currently, January is the cheapest month in which you can book a flight from South Africa to Missouri (average of R15 358). Flying from South Africa to Missouri in August is currently the most expensive (average of R16 784). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 23 January 2026.
See what other customers who have flown with KLM, Virgin Atlantic, andQatar Airways from South Africa to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 442 reviews
Check prices

Comfort

7,6

Entertainment

7,1

Food

7,3

Overall

7,7

Boarding

7,8

Crew

8,4

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7,7
Good
1 442 reviews
KLM
7,7
Good
1 442 reviews
Check prices

Comfort

7,6

Entertainment

7,1

Food

7,3

Overall

7,7

Boarding

7,8

Crew

8,4

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Virgin Atlantic
7,5
Good
678 reviews
KLM
7,7
Good
1 442 reviews
Check prices

Comfort

7,6

Entertainment

7,1

Food

7,3

Overall

7,7

Boarding

7,8

Crew

8,4

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Qatar Airways
7,4
Good
3 723 reviews
KLM
7,7
Good
1 442 reviews
Check prices

Comfort

7,6

Entertainment

7,1

Food

7,3

Overall

7,7

Boarding

7,8

Crew

8,4

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
United Airlines
7,4
Good
9 194 reviews
KLM
7,7
Good
1 442 reviews
Check prices

Comfort

7,6

Entertainment

7,1

Food

7,3

Overall

7,7

Boarding

7,8

Crew

8,4

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
British Airways
6,7
Okay
7 692 reviews
KLM
7,7
Good
1 442 reviews
Check prices

Comfort

7,6

Entertainment

7,1

Food

7,3

Overall

7,7

Boarding

7,8

Crew

8,4

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from South Africa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Missouri?

    Departing from South Africa to Missouri will take you 22h 08m. There are 13786 km between South Africa and Missouri. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines to fly from South Africa to Missouri one-way?

    To fly one-way, consider booking your trip with Qatar Airways, which is currently one of the cheapest options available, starting at R10 894. KLM flights start at R12 838 while deals on Virgin Atlantic start at R14 045 one-way.

  • Can I find deals for flights from South Africa to Missouri that include hotel bookings?

    Yes. In addition to deals on South Africa to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Missouri.

  • Can I find deals for business class flights from South Africa to Missouri?

    Yes. Cheapflights offers flight deals from South Africa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Missouri?

    Currently, January is the cheapest month in which you can book a flight from South Africa to Missouri (average of R15 358). Flying from South Africa to Missouri in August is currently the most expensive (average of R16 784). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Africa to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Atlanta flights
OR Tambo to John F Kennedy Intl flights
OR Tambo to LaGuardia flights
Cape Town to Atlanta flights
OR Tambo to Dulles Intl flights
OR Tambo to Los Angeles flights
OR Tambo to Miami flights
Cape Town to Dulles Intl flights
OR Tambo to Orlando flights
Cape Town to San Francisco flights
Cape Town to Seattle flights
OR Tambo to Reagan-National flights
OR Tambo to Boston flights
OR Tambo to Seattle flights
Cape Town to Las Vegas flights
OR Tambo to Ontario flights
OR Tambo to Love Field flights
Cape Town to Los Angeles flights
Cape Town to Miami flights
OR Tambo to San Francisco flights
OR Tambo to Santa Ana flights
OR Tambo to Oklahoma City flights
OR Tambo to Hobby flights
OR Tambo to Fort Lauderdale flights
OR Tambo to Minneapolis flights
Cape Town to Ontario flights
Durban to Dulles Intl flights
Cape Town to Fort Lauderdale flights
OR Tambo to George Bush Intcntl flights
OR Tambo to St. Louis flights
OR Tambo to O'Hare Intl flights

Top 8 airlines flying from South Africa to Missouri

Discover the top 8 airlines that operate flights from South Africa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 23 January 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapestR15 893AverageR18 868FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
KLMCheapestR15 935AverageR19 469FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapestR15 973AverageR21 055FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Air FranceCheapestR16 007AverageR20 394FlexibilityNo cancel feeOn-time77%
Search Air France flights
LufthansaCheapestR16 404AverageR20 548FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Virgin AtlanticCheapestR16 588AverageR17 811FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
British AirwaysCheapestR16 639AverageR18 935FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Qatar AirwaysCheapestR19 748AverageR27 223FlexibilityNo cancel feeOn-time68%
Search Qatar Airways flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Missouri?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from South Africa to Missouri. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from South Africa to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from South Africa.

Can Cheapflights find flights from South Africa to Missouri with no change fees?

Need flexible booking options for your flight to Missouri from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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