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Cheap flights from Cape Town to Panama City from R13 626

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/5. Fares are subject to change and may not be available on all flights or dates of travel.
CPT — PTY
May 17 — May 241
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cape Town to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Cape Town to Panama City
Explore the most affordable flight options available from Cape Town to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 April 2026.

Wed 27/519:30
CPT
-
PTY
2 stops47h 44m
Multiple Airlines
Wed 3/621:30
PTY
-
CPT
2 stops32h 25m
Multiple Airlines
Deal found 12/4R28 350
Sat 30/516:35
CPT
-
PTY
2 stops32h 50m
Turkish Airlines
Sat 6/620:10
PTY
-
CPT
1 stop32h 40m
Turkish Airlines
Deal found 15/4R30 266
Sat 30/519:30
CPT
-
PTY
2 stops47h 44m
Multiple Airlines
Sat 6/613:14
PTY
-
CPT
2 stops40h 41m
Multiple Airlines
Deal found 15/4R30 528
Wed 27/523:15
CPT
-
PTY
2 stops27h 30m
KLM
Wed 3/618:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 12/4R35 458
Fri 29/518:00
CPT
-
PTY
2 stops33h 41m
United Airlines
Fri 5/617:51
PTY
-
CPT
2 stops38h 29m
United Airlines
Deal found 14/4R36 653

Find flight deals from Cape Town to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cape Town (CPT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 17 April 2026.

Round-trip from

R28 350

One-way from

R13 626

Popular in

January

Cheapest in

April

Average price

R18 523
Qatar Airways
  • Qatar Airways
  • 27/5-3/6
  • 4 total stops
  • 80h 09m total
  • Cape Town to Panama City
Search Deals
28/5
  • 28/5
  • 3 total stops
  • 49h 10m total
  • Cape Town to Panama City
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R62 282 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R21 407 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Cape Town to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 17 April 2026.
Use the filters below to find and compare flights from Cape Town to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 27/5

19:30-12:14

2 stops47h 44m

Panama City Tocumen Intl

Wed 3/6

21:30-12:55

2 stops32h 25m

R28 350
Fastest return journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 30/5

16:35-18:25

2 stops32h 50m

Panama City Tocumen Intl

Sat 6/6

20:10-11:50

1 stop32h 40m

R30 266

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 30/5

19:30-12:14

2 stops47h 44m

Panama City Tocumen Intl

Sat 6/6

13:14-12:55

2 stops40h 41m

R30 528

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 27/5

23:15-19:45

2 stops27h 30m

Panama City Tocumen Intl

Wed 3/6

18:50-21:25

1 stop43h 35m

R35 458

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 29/5

18:00-20:41

2 stops33h 41m

Panama City Tocumen Intl

Fri 5/6

17:51-15:20

2 stops38h 29m

R36 653

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 13/9

20:00-19:31

2 stops30h 31m

Panama City Tocumen Intl

Thu 17/9

18:06-15:20

2 stops62h 14m

R37 734

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 30/5

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Sat 6/6

18:50-21:25

1 stop43h 35m

R42 565
Cheapest one-way

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 28/5

15:05-9:15

3 stops49h 10m

R13 626

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 26/4

19:30-12:46

2 stops48h 16m

R18 556

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 19/6

20:00-6:37

2 stops41h 37m

R20 325

Flights are sorted by cheapest return flights first.

Deals found on 12/4

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Cape Town to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cape Town with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Town to Panama City

What is the cheapest month to book a flight from Cape Town to Panama City?

Currently, April is the cheapest month in which you can book a flight from Cape Town to Panama City (average of R18 523). Flying from Cape Town to Panama City in January is currently the most expensive (average of R37 767). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 17 April 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from Cape Town to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 499 reviews
Check prices

Entertainment

7,2

Comfort

7,7

Overall

7,8

Food

7,3

Boarding

7,8

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 499 reviews
KLM
7,8
Good
1 499 reviews
Check prices

Entertainment

7,2

Comfort

7,7

Overall

7,8

Food

7,3

Boarding

7,8

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,4
Good
1 572 reviews
KLM
7,8
Good
1 499 reviews
Check prices

Entertainment

7,2

Comfort

7,7

Overall

7,8

Food

7,3

Boarding

7,8

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 603 reviews
KLM
7,8
Good
1 499 reviews
Check prices

Entertainment

7,2

Comfort

7,7

Overall

7,8

Food

7,3

Boarding

7,8

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Cape Town to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cape Town to Panama City?

    Departing from Cape Town to Panama City will take you 27h 30m. Airlines will cover a distance of 11294 km. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Cape Town to Panama City round-trip?

    Flying on United Airlines is currently your cheapest option to Panama City, with prices starting at R18 757. Additional round-trip tickets that might be worth considering are offered by KLM and Air France, with the lowest prices starting at R22 916 and R23 743, respectively. United Airlines is 19% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Cape Town to Panama City that include hotel bookings?

    Yes. In addition to deals on Cape Town to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cape Town to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Town to Panama City.

  • Can I find deals for business class flights from Cape Town to Panama City?

    Yes. Cheapflights offers flight deals from Cape Town to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Town to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Cape Town to Panama City (average of R18 523). Flying from Cape Town to Panama City in January is currently the most expensive (average of R37 767). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Fly from Cape Town to Panama City on these airlines

Choose from the following airlines for your flight from Cape Town to Panama City. Flights are based on user searches made on Cheapflights and were last updated on 17 April 2026.
United Airlines flights from Cape Town Intl to Panama City Tocumen Intl
KLM flights from Cape Town Intl to Panama City Tocumen Intl

Top 3 airlines flying from Cape Town to Panama City

Discover the top 3 airlines that operate flights from Cape Town to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 17 April 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 757AverageR21 039FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR22 916AverageR25 602FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 743AverageR24 463FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Cape Town to Panama City?

Cheapflights makes it easy to find Cape Town to Panama City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Cape Town to Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Cape Town to Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Cape Town to Panama City with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Cape Town to Panama City, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Cape Town to Panama City become cheaper?

Of course! You can now track prices for flights from Cape Town to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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