R9 210+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Jan 26 — Feb 21
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 27 December 2025.

Good round-trip deal

R16 873 or less

Good one-way deal

R1 282 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 27 December 2025.

Mon 9/218:31PTY - CPT
2 stops33h 29mLufthansa
Mon 16/218:45CPT - PTY
2 stops45h 09mLufthansa
Deal found 26/12R15 456
Mon 2/218:31PTY - JNB
2 stops31h 59mLufthansa
Mon 9/219:45JNB - PTY
2 stops44h 09mLufthansa
Deal found 24/12R15 656
Mon 9/218:31PTY - JNB
2 stops31h 59mLufthansa
Mon 16/219:45JNB - PTY
2 stops44h 09mLufthansa
Deal found 26/12R15 673
Mon 16/222:29PTY - CPT
2 stops36h 31mUnited Airlines
Thu 26/220:50CPT - PTY
2 stops30h 45mUnited Airlines
Deal found 25/12R16 605
Wed 4/211:57PTY - CPT
2 stops45h 13mUnited Airlines
Sun 8/220:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 24/12R16 755
Mon 2/218:45PTY - JNB
1 stop44h 20mMultiple Airlines
Mon 9/219:20JNB - PTY
1 stop31h 50mMultiple Airlines
Deal found 24/12R16 938
Mon 2/218:45PTY - JNB
1 stop44h 20mKLM
Mon 9/219:20JNB - PTY
2 stops28h 10mKLM
Deal found 24/12R17 271
Mon 9/218:45PTY - JNB
1 stop44h 20mKLM
Mon 16/219:20JNB - PTY
2 stops28h 10mKLM
Deal found 26/12R17 288
Wed 18/27:55PTY - JNB
2 stops27h 40mUnited Airlines
Sun 22/219:45JNB - PTY
2 stops41h 28mUnited Airlines
Deal found 24/12R17 688
Mon 13/421:55PTY - JNB
2 stops40h 25mMultiple Airlines
Mon 20/423:15JNB - PTY
1 stop24h 35mMultiple Airlines
Deal found 26/12R18 138
Mon 9/221:45PTY - CPT
1 stop31h 05mTurkish Airlines
Mon 23/217:15CPT - PTY
1 stop30h 50mTurkish Airlines
Deal found 26/12R18 421
Wed 1/420:05PTY - JNB
1 stop31h 25mTurkish Airlines
Fri 3/418:00JNB - PTY
1 stop33h 25mTurkish Airlines
Deal found 25/12R18 421

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 27 December 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

18:31-11:00

2 stops33h 29m

Cape Town Intl

Mon 16/2

18:45-8:54

2 stops45h 09m

R15 456

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/2

18:31-9:30

2 stops31h 59m

Johannesburg OR Tambo

Mon 9/2

19:45-8:54

2 stops44h 09m

R15 656

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 9/2

18:31-9:30

2 stops31h 59m

Johannesburg OR Tambo

Mon 16/2

19:45-8:54

2 stops44h 09m

R15 673

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 16/2

22:29-18:00

2 stops36h 31m

Cape Town Intl

Thu 26/2

20:50-20:35

2 stops30h 45m

R16 605

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

9:11-18:00

2 stops25h 49m

Cape Town Intl

Sun 8/2

20:50-13:31

1 stop23h 41m

R16 739

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/2

18:45-22:05

1 stop44h 20m

Johannesburg OR Tambo

Mon 9/2

19:20-16:30

2 stops28h 10m

R17 271

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 9/2

18:45-22:05

1 stop44h 20m

Johannesburg OR Tambo

Mon 16/2

19:20-16:30

2 stops28h 10m

R17 288

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 19/5

18:41-9:30

2 stops55h 49m

Cape Town Intl

Tue 26/5

20:00-20:27

2 stops31h 27m

R17 538

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 18/2

7:55-18:35

2 stops27h 40m

Johannesburg OR Tambo

Sun 22/2

19:45-6:13

2 stops41h 28m

R17 688

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

21:55-21:20

2 stops40h 25m

Johannesburg OR Tambo

Mon 20/4

23:15-16:50

1 stop24h 35m

R18 138

Flights are sorted by cheapest return flights first.

Deals found on 24/12

Showing 1-10 of 21 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (246 flights per day), San José (160 flights per day) and Miami (131 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From R1 282
Madrid Barajas
Madrid Barajas
From R16 873

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 282. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R1 282
Madrid Barajas
Madrid Barajas
From R16 873

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 27 December 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cali, Barranquilla. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R16 388 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R16 630 to fly from Panama City.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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