R8 751+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Jan 20 — Jan 271
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 21 December 2025.

Good round-trip deal

R16 983 or less

Good one-way deal

R1 291 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 21 December 2025.

Tue 31/319:25PTY - CPT
2 stops60h 55mUnited Airlines
Tue 14/420:00CPT - PTY
2 stops27h 12mUnited Airlines
Deal found 20/12R16 713
Wed 4/27:55PTY - CPT
2 stops27h 05mUnited Airlines
Sun 8/220:50CPT - PTY
1 stop30h 45mUnited Airlines
Deal found 18/12R16 847
Mon 13/418:50PTY - JNB
1 stop43h 30mKLM
Mon 20/423:15JNB - PTY
1 stop24h 35mKLM
Deal found 19/12R17 049
Sun 10/518:50PTY - CPT
1 stop43h 35mKLM
Sat 23/523:15CPT - PTY
1 stop24h 35mKLM
Deal found 21/12R17 065
Sun 10/522:10PTY - CPT
2 stops40h 15mMultiple Airlines
Sat 23/523:15CPT - PTY
1 stop24h 35mMultiple Airlines
Deal found 21/12R17 401
Wed 4/28:16PTY - JNB
2 stops27h 19mUnited Airlines
Sun 8/219:45JNB - PTY
2 stops41h 28mUnited Airlines
Deal found 18/12R17 803
Tue 19/518:02PTY - CPT
2 stops56h 28mUnited Airlines
Tue 26/520:00CPT - PTY
3 stops31h 27mUnited Airlines
Deal found 19/12R18 557
Mon 13/421:55PTY - JNB
2 stops40h 25mAir France
Mon 20/423:15JNB - PTY
2 stops27h 30mAir France
Deal found 20/12R19 932
Tue 19/520:05PTY - CPT
1 stop32h 45mTurkish Airlines
Tue 26/516:35CPT - PTY
1 stop34h 50mTurkish Airlines
Deal found 19/12R19 949
Wed 1/422:20PTY - JNB
1 stop29h 10mTurkish Airlines
Fri 3/418:00JNB - PTY
1 stop33h 25mTurkish Airlines
Deal found 20/12R20 401
Fri 9/117:51PTY - CPT
2 stops39h 19mUnited Airlines
Sun 25/120:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 19/12R20 452
Wed 4/221:45PTY - JNB
1 stop30h 05mTurkish Airlines
Sun 8/219:05JNB - PTY
2 stops29h 00mTurkish Airlines
Deal found 19/12R22 581

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 21 December 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 31/3

19:25-15:20

2 stops60h 55m

Cape Town Intl

Tue 14/4

20:00-16:12

2 stops27h 12m

R16 713

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

7:55-18:00

2 stops27h 05m

Cape Town Intl

Sun 8/2

20:50-20:35

1 stop30h 45m

R16 847

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Mon 20/4

23:15-16:50

1 stop24h 35m

R17 049

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 19/5

18:02-9:30

2 stops56h 28m

Cape Town Intl

Tue 26/5

20:00-20:27

3 stops31h 27m

R18 557

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 4/2

7:55-18:35

2 stops27h 40m

Johannesburg OR Tambo

Sun 8/2

19:45-10:33

2 stops45h 48m

R18 574

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

21:55-21:20

2 stops40h 25m

Johannesburg OR Tambo

Mon 20/4

23:15-19:45

2 stops27h 30m

R19 932

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 19/5

20:05-11:50

1 stop32h 45m

Cape Town Intl

Tue 26/5

16:35-20:25

1 stop34h 50m

R19 949

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 1/4

20:05-10:30

1 stop31h 25m

Johannesburg OR Tambo

Fri 3/4

18:00-20:25

1 stop33h 25m

R20 401

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 9/1

17:51-16:10

2 stops39h 19m

Cape Town Intl

Sun 25/1

20:50-13:31

1 stop23h 41m

R20 452

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 4/2

21:45-10:50

1 stop30h 05m

Johannesburg OR Tambo

Sun 8/2

19:05-17:05

2 stops29h 00m

R22 581

Flights are sorted by cheapest return flights first.

Deals found on 20/12

Showing 1-10 of 20 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (242 flights per day), San José (160 flights per day) and Miami (129 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From R1 291
Madrid Barajas
Madrid Barajas
From R16 983

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 291. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R1 291
Madrid Barajas
Madrid Barajas
From R16 983

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 December 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cali, Barranquilla. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R16 494 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R16 739 to fly from Panama City.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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