R13 961+ Cheap flights from Panama City
This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
What to know about flights from Panama City
Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 18 September 2025.
Cheapest airline | United Airlines |
|---|---|
Good round-trip deal | R17 592 or less |
Good one-way deal | R1 337 or less |
Find flights from Panama City
Cheapest flights from Panama CityExplore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 18 September 2025.
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 18 September 2025.
Find flights from Panama City within your budget
Fly to
Route
Depart
Return
Price
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Tue 3/2
22:29-18:35
2 stops37h 06m
Johannesburg OR Tambo
Tue 10/2
22:00-14:22
2 stops47h 22m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Tue 3/2
22:20-12:10
1 stop30h 50m
Johannesburg OR Tambo
Tue 10/2
19:40-20:10
1 stop31h 30m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Sun 25/1
9:11-7:40
2 stops39h 29m
Cape Town Intl
Sat 7/2
20:50-6:37
2 stops40h 47m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Tue 28/10
18:24-18:35
2 stops41h 11m
Johannesburg OR Tambo
Sun 9/11
19:45-20:35
2 stops31h 50m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Mon 9/2
9:13-16:10
1 stop23h 57m
Cape Town Intl
Mon 23/2
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Sun 12/10
9:45-14:35
2 stops45h 50m
Cape Town Intl
Tue 4/11
20:50-20:35
1 stop30h 45m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Mon 13/10
18:50-21:25
1 stop43h 35m
Cape Town Intl
Wed 5/11
23:45-20:10
2 stops27h 25m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Wed 15/10
18:50-21:30
2 stops43h 40m
Cape Town Intl
Wed 22/10
14:00-17:45
2 stops34h 45m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Tue 30/9
9:45-9:45
2 stops41h 00m
Cape Town Intl
Thu 30/10
20:50-10:33
2 stops44h 43m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Sun 1/3
19:09-18:35
2 stops40h 26m
Johannesburg OR Tambo
Wed 18/3
10:25-19:02
2 stops39h 37m
Best time to book a flight from Panama City
Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Travel insights for flights from Panama City
Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.
What are popular destinations to fly to from Panama City?
From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (254 flights per day), San José (172 flights per day) and Guatemala City (112 flights per day).
What is the cheapest place to fly to from Panama City?
The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 337. Explore other affordable destinations below.
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Direct flights from Panama
Book a direct flight from one of these other cities located in Panama.
Related info for your journey
Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 September 2025.
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How does Cheapflights help users find flights from Panama City?
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Why should you use Cheapflights to find cheap flight tickets from Panama City?
Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.
Can Cheapflights find flights from Panama City with no change fees?
Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
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