R9 438+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Dec 17 — Dec 241
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 17 November 2025.

Cheapest airline

United Airlines

Good round-trip deal

R17 290 or less

Good one-way deal

R1 314 or less
On average, United Airlines currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of R24 886).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 17 November 2025.

Sun 1/218:41PTY - CPT
1 stop38h 29mUnited Airlines
Thu 19/220:50CPT - PTY
2 stops27h 18mUnited Airlines
Deal found 15/11R16 998
Fri 30/121:49PTY - CPT
2 stops35h 21mUnited Airlines
Fri 13/220:50CPT - PTY
2 stops30h 45mUnited Airlines
Deal found 15/11R17 237
Mon 2/29:11PTY - CPT
1 stop23h 59mUnited Airlines
Mon 16/218:45CPT - PTY
2 stops32h 50mUnited Airlines
Deal found 15/11R17 954
Fri 30/122:29PTY - CPT
1 stop34h 41mUnited Airlines
Sat 14/218:45CPT - PTY
2 stops32h 49mUnited Airlines
Deal found 15/11R17 971
Mon 13/49:11PTY - JNB
2 stops25h 34mUnited Airlines
Mon 20/419:00JNB - PTY
2 stops42h 13mUnited Airlines
Deal found 16/11R17 971
Mon 9/222:29PTY - CPT
2 stops50h 11mUnited Airlines
Mon 23/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 16/11R18 551
Thu 5/210:00PTY - CPT
2 stops38h 40mUnited Airlines
Mon 16/29:30CPT - PTY
2 stops41h 32mUnited Airlines
Deal found 15/11R18 568
Mon 9/221:45PTY - CPT
1 stop31h 05mTurkish Airlines
Mon 23/217:15CPT - PTY
1 stop30h 50mTurkish Airlines
Deal found 15/11R18 858
Mon 13/422:15PTY - JNB
1 stop29h 20mTurkish Airlines
Mon 20/418:00JNB - PTY
1 stop31h 30mTurkish Airlines
Deal found 15/11R18 858
Mon 2/218:45PTY - CPT
2 stops28h 05mMultiple Airlines
Tue 17/218:25CPT - PTY
2 stops32h 30mMultiple Airlines
Deal found 15/11R20 616
Sun 1/222:20PTY - CPT
2 stops36h 00mAir France
Mon 16/215:20CPT - PTY
2 stops35h 50mAir France
Deal found 15/11R20 650
Wed 1/420:10PTY - JNB
1 stop31h 25mTurkish Airlines
Fri 3/418:00JNB - PTY
1 stop33h 20mTurkish Airlines
Deal found 15/11R20 753

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 17 November 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

9:30-18:00

2 stops25h 30m

Cape Town Intl

Tue 17/2

20:50-13:31

1 stop23h 41m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

22:29-16:10

1 stop34h 41m

Cape Town Intl

Wed 18/2

20:50-20:27

2 stops30h 37m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 3/2

9:11-18:00

2 stops25h 49m

Cape Town Intl

Fri 13/2

20:50-20:35

1 stop30h 45m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 31/1

9:11-16:10

1 stop23h 59m

Cape Town Intl

Fri 13/2

20:50-13:31

1 stop23h 41m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 30/1

22:29-16:10

1 stop34h 41m

Cape Town Intl

Wed 18/2

20:50-20:35

2 stops30h 45m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 3/2

8:16-18:00

2 stops26h 44m

Cape Town Intl

Tue 17/2

20:50-20:35

1 stop30h 45m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/2

9:11-16:10

1 stop23h 59m

Cape Town Intl

Thu 19/2

20:50-20:35

2 stops30h 45m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

22:29-16:10

1 stop34h 41m

Cape Town Intl

Thu 19/2

20:50-17:08

2 stops27h 18m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/2

8:16-16:10

2 stops24h 54m

Cape Town Intl

Tue 17/2

20:50-20:27

2 stops30h 37m

R16 998

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 30/1

22:29-16:10

1 stop34h 41m

Cape Town Intl

Thu 19/2

20:50-17:08

2 stops27h 18m

R16 998

Flights are sorted by cheapest return flights first.

Deals found on 14/11

Showing 1-10 of 23 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (254 flights per day), San José (149 flights per day) and Guatemala City (107 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From R1 314
Madrid Barajas
Madrid Barajas
From R17 290

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 314. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R1 314
Madrid Barajas
Madrid Barajas
From R17 290

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 17 November 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cancún, Guatemala City. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R16 792 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R17 041 to fly from Panama City.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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