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R9 459+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — JNB
Jan 2 — Jan 91
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 3 December 2025.

Good round-trip deal

R17 329 or less

Good one-way deal

R1 317 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 3 December 2025.

Wed 14/121:49PTY - CPT
2 stops35h 21mUnited Airlines
Sun 18/120:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 1/12R17 037
Wed 4/216:41PTY - CPT
2 stops40h 29mUnited Airlines
Sun 8/220:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 30/11R17 191
Sun 25/119:40PTY - JNB
2 stops39h 55mUnited Airlines
Sun 1/215:05JNB - PTY
2 stops46h 08mUnited Airlines
Deal found 3/12R17 225
Mon 13/418:50PTY - CPT
1 stop28h 00mKLM
Wed 29/47:40CPT - PTY
2 stops43h 05mKLM
Deal found 1/12R17 892
Mon 9/219:20PTY - CPT
2 stops39h 40mUnited Airlines
Mon 23/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 1/12R17 961
Sat 17/122:29PTY - JNB
2 stops37h 06mUnited Airlines
Sat 24/119:45JNB - PTY
2 stops31h 50mUnited Airlines
Deal found 3/12R17 978
Sun 25/122:20PTY - JNB
2 stops40h 45mKLM
Sun 1/223:59JNB - PTY
1 stop23h 31mKLM
Deal found 3/12R18 063
Thu 5/218:24PTY - JNB
2 stops41h 11mUnited Airlines
Mon 9/219:45JNB - PTY
2 stops41h 28mUnited Airlines
Deal found 2/12R18 132
Sun 1/222:20PTY - JNB
1 stop30h 50mAir France
Sun 8/219:20JNB - PTY
1 stop31h 50mAir France
Deal found 1/12R18 252
Thu 12/216:41PTY - CPT
2 stops64h 29mUnited Airlines
Mon 23/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 3/12R18 884
Mon 13/418:50PTY - JNB
1 stop43h 30mKLM
Mon 20/423:15JNB - PTY
2 stops27h 30mKLM
Deal found 2/12R20 150
Sun 25/122:20PTY - JNB
1 stop30h 50mAir France
Sun 1/219:20JNB - PTY
1 stop31h 50mAir France
Deal found 3/12R20 612

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 3 December 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 13/1

9:11-18:00

2 stops25h 49m

Cape Town Intl

Sun 18/1

20:50-20:35

1 stop30h 45m

R17 037

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

16:41-16:10

2 stops40h 29m

Cape Town Intl

Sun 8/2

20:50-13:31

1 stop23h 41m

R17 191

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 25/1

19:40-18:35

2 stops39h 55m

Johannesburg OR Tambo

Sun 1/2

15:05-6:13

2 stops46h 08m

R17 225

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R17 961

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 17/1

22:29-18:35

2 stops37h 06m

Johannesburg OR Tambo

Sat 24/1

19:45-20:35

2 stops31h 50m

R17 978

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 25/1

22:20-22:05

2 stops40h 45m

Johannesburg OR Tambo

Sun 1/2

23:59-16:30

1 stop23h 31m

R18 063

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 5/2

18:24-18:35

2 stops41h 11m

Johannesburg OR Tambo

Mon 9/2

19:45-6:13

2 stops41h 28m

R18 132

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 1/2

22:20-12:10

1 stop30h 50m

Johannesburg OR Tambo

Sun 8/2

23:59-20:10

2 stops27h 11m

R18 782

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 12/2

16:41-16:10

2 stops64h 29m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R18 884

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Mon 20/4

23:15-19:45

2 stops27h 30m

R20 150

Flights are sorted by cheapest return flights first.

Deals found on 3/12

Showing 1-10 of 26 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, September is the cheapest month in which you can book a flight from Panama City (average of R13 941). Flying from Panama City in August will prove the most costly (average of R40 078). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

When flying from Panama City check dates and pricing for the following: United Airlines. As it departs for the following popular destinations: Johannesburg.

United Airlines
United Airlines
From R12 798

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (234 flights per day), San José (139 flights per day) and Guatemala City (96 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From R1 317
Madrid Barajas
Madrid Barajas
From R17 329

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 317. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R1 317
Madrid Barajas
Madrid Barajas
From R17 329

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Get a feel of what it's like to fly with United Airlines from Panama City by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
9 063 reviews
Check prices

Food

6,6

Crew

8,1

Boarding

7,7

Overall

7,4

Comfort

7,3

Entertainment

7,1

Reviews

1 / 20
2,0
Mediocre

Anonymous,Oct 2024

EWR - DEN

Terribly delayed flight, missed ongoing flight, hotel very downmarket Food voucher not accepted in hotel
United Airlines
7,4
Good
9 063 reviews
United Airlines
7,4
Good
9 063 reviews
Check prices

Food

6,6

Crew

8,1

Boarding

7,7

Overall

7,4

Comfort

7,3

Entertainment

7,1

Reviews

1 / 20
2,0
Mediocre

Anonymous,Oct 2024

EWR - DEN

Terribly delayed flight, missed ongoing flight, hotel very downmarket Food voucher not accepted in hotel

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 3 December 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cali, Cartagena. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R16 831 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R17 080 to fly from Panama City.

  • What is the cheapest month to fly from Panama City?

    September is currently the cheapest month to fly from Panama City. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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