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R9 546+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — JNB
Nov 28 — Dec 51
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 29 October 2025.

Cheapest airline

United Airlines

Good round-trip deal

R17 363 or less

Good one-way deal

R1 320 or less
On average, United Airlines currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of R24 993).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 29 October 2025.

Wed 26/1119:20PTY - CPT
2 stops37h 50mUnited Airlines
Wed 3/1220:50CPT - PTY
2 stops30h 45mUnited Airlines
Deal found 27/10R17 053
Wed 26/1118:45PTY - CPT
1 stop44h 10mMultiple Airlines
Wed 3/127:55CPT - PTY
1 stop43h 15mMultiple Airlines
Deal found 27/10R17 636
Mon 9/219:20PTY - CPT
2 stops39h 40mUnited Airlines
Mon 23/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 28/10R18 030
Sat 6/129:11PTY - JNB
2 stops49h 14mUnited Airlines
Thu 29/119:45JNB - PTY
2 stops31h 50mUnited Airlines
Deal found 28/10R18 202
Sun 8/218:45PTY - CPT
2 stops52h 05mKLM
Thu 12/214:00CPT - PTY
2 stops33h 30mKLM
Deal found 27/10R19 059
Fri 13/218:45PTY - CPT
1 stop34h 05mTurkish Airlines
Mon 16/217:15CPT - PTY
2 stops30h 50mTurkish Airlines
Deal found 28/10R20 516
Sat 6/1221:45PTY - JNB
1 stop30h 05mTurkish Airlines
Thu 29/119:10JNB - PTY
2 stops28h 55mTurkish Airlines
Deal found 28/10R20 516
Sun 15/218:45PTY - JNB
1 stop33h 05mTurkish Airlines
Thu 19/219:10JNB - PTY
2 stops28h 55mTurkish Airlines
Deal found 28/10R21 235
Mon 9/222:20PTY - CPT
1 stop24h 30mAir France
Mon 23/27:55CPT - PTY
1 stop43h 15mAir France
Deal found 29/10R22 452
Sat 6/1218:45PTY - JNB
2 stops34h 25mKLM
Thu 29/123:59JNB - PTY
3 stops36h 55mKLM
Deal found 28/10R22 881
Mon 13/418:50PTY - JNB
1 stop43h 30mKLM
Mon 20/423:15JNB - PTY
1 stop24h 35mKLM
Deal found 28/10R24 749
Fri 13/212:04PTY - CPT
2 stops45h 06mUnited Airlines
Mon 16/29:30CPT - PTY
2 stops56h 03mUnited Airlines
Deal found 28/10R25 177

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 29 October 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 26/11

22:29-16:10

1 stop34h 41m

Cape Town Intl

Wed 3/12

20:50-20:35

2 stops30h 45m

R17 053

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 26/11

18:45-21:55

1 stop44h 10m

Cape Town Intl

Wed 3/12

7:55-20:10

1 stop43h 15m

R17 636

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 23/2

18:45-13:31

2 stops49h 46m

R18 030

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 6/12

9:11-17:25

2 stops49h 14m

Johannesburg OR Tambo

Thu 29/1

19:45-20:35

2 stops31h 50m

R18 202

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 8/2

18:45-5:50

2 stops52h 05m

Cape Town Intl

Thu 12/2

14:00-16:30

2 stops33h 30m

R19 059

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 13/2

18:45-11:50

1 stop34h 05m

Cape Town Intl

Mon 16/2

17:15-17:05

2 stops30h 50m

R20 516

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 15/2

18:45-10:50

1 stop33h 05m

Johannesburg OR Tambo

Thu 19/2

19:10-17:05

2 stops28h 55m

R21 235

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

22:20-5:50

1 stop24h 30m

Cape Town Intl

Mon 23/2

7:55-20:10

1 stop43h 15m

R22 452

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 6/12

18:45-12:10

2 stops34h 25m

Johannesburg OR Tambo

Thu 29/1

23:59-5:54

3 stops36h 55m

R22 881

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Mon 20/4

23:15-16:50

1 stop24h 35m

R24 749

Flights are sorted by cheapest return flights first.

Deals found on 28/10

Showing 1-10 of 18 results
1
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, September is the cheapest month in which you can book a flight from Panama City (average of R13 968). Flying from Panama City in August will prove the most costly (average of R40 157). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

When flying from Panama City check dates and pricing for the following: United Airlines. As it departs for the following popular destinations: Johannesburg.

United Airlines
United Airlines
From R17 383

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (244 flights per day), San José (139 flights per day) and Miami (103 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From R1 320
Madrid Barajas
Madrid Barajas
From R17 363

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 320. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R1 320
Madrid Barajas
Madrid Barajas
From R17 363

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Get a feel of what it's like to fly with United Airlines from Panama City by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
8 999 reviews
Check prices

Overall

7,4

Boarding

7,7

Crew

8,1

Entertainment

7,1

Food

6,6

Comfort

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Oct 2024

EWR - DEN

Terribly delayed flight, missed ongoing flight, hotel very downmarket Food voucher not accepted in hotel
United Airlines
7,4
Good
8 999 reviews
United Airlines
7,4
Good
8 999 reviews
Check prices

Overall

7,4

Boarding

7,7

Crew

8,1

Entertainment

7,1

Food

6,6

Comfort

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Oct 2024

EWR - DEN

Terribly delayed flight, missed ongoing flight, hotel very downmarket Food voucher not accepted in hotel

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 29 October 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cancún, Cartagena. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R16 864 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R17 114 to fly from Panama City.

  • What is the cheapest month to fly from Panama City?

    September is currently the cheapest month to fly from Panama City. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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