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R13 603+ Cheap flights from Panama City

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — JNB
Sep 2 — Sep 91
1 adult

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 28 August 2025.

Cheapest airline

United Airlines

Good round-trip deal

R17 921 or less

Good one-way deal

R1 362 or less
On average, United Airlines currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of R25 795).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 28 August 2025.

Tue 23/915:30PTY - CPT
2 stops64h 50mUnited Airlines
Tue 30/920:00CPT - PTY
1 stop24h 31mUnited Airlines
Deal found 27/8R18 503
Fri 26/912:04PTY - JNB
2 stops46h 41mUnited Airlines
Fri 3/1019:00JNB - PTY
2 stops42h 13mUnited Airlines
Deal found 27/8R18 591
Sun 8/27:55PTY - JNB
2 stops27h 40mUnited Airlines
Sun 8/322:00JNB - PTY
2 stops43h 33mUnited Airlines
Deal found 27/8R18 644
Wed 28/118:45PTY - JNB
1 stop44h 20mKLM
Sun 15/223:59JNB - PTY
1 stop23h 31mKLM
Deal found 26/8R19 175
Tue 28/109:25PTY - JNB
2 stops41h 05mUnited Airlines
Sun 9/1119:45JNB - PTY
2 stops41h 28mUnited Airlines
Deal found 25/8R19 564
Wed 17/99:30PTY - JNB
2 stops40h 05mUnited Airlines
Wed 24/919:00JNB - PTY
2 stops49h 31mUnited Airlines
Deal found 27/8R19 582
Tue 28/1022:20PTY - JNB
1 stop30h 30mMultiple Airlines
Sun 9/1123:59JNB - PTY
2 stops44h 26mMultiple Airlines
Deal found 27/8R19 830
Fri 12/99:13PTY - JNB
2 stops25h 32mUnited Airlines
Mon 22/919:00JNB - PTY
2 stops32h 34mUnited Airlines
Deal found 27/8R22 377
Wed 28/118:45PTY - JNB
1 stop44h 20mMultiple Airlines
Sun 15/223:59JNB - PTY
2 stops27h 11mMultiple Airlines
Deal found 26/8R22 678
Wed 17/918:50PTY - JNB
1 stop43h 45mKLM
Wed 24/923:15JNB - PTY
1 stop24h 35mKLM
Deal found 27/8R22 890
Wed 17/911:00PTY - JNB
2 stops42h 15mMultiple Airlines
Thu 2/1015:05JNB - PTY
2 stops26h 05mMultiple Airlines
Deal found 27/8R23 102
Wed 17/918:50PTY - JNB
1 stop43h 45mMultiple Airlines
Wed 24/918:50JNB - PTY
2 stops29h 00mMultiple Airlines
Deal found 27/8R23 261

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 28 August 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 23/9

15:30-15:20

2 stops64h 50m

Cape Town Intl

Tue 30/9

20:00-18:37

2 stops29h 37m

R18 503

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 26/9

12:04-17:45

2 stops46h 41m

Johannesburg OR Tambo

Fri 3/10

19:00-6:13

2 stops42h 13m

R18 591

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 8/2

7:55-18:35

2 stops27h 40m

Johannesburg OR Tambo

Sun 8/3

22:00-10:33

2 stops43h 33m

R18 644

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 28/1

18:45-22:05

1 stop44h 20m

Johannesburg OR Tambo

Sun 15/2

23:59-16:30

1 stop23h 31m

R19 175

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/10

9:25-9:30

2 stops41h 05m

Johannesburg OR Tambo

Sun 9/11

19:45-6:13

2 stops41h 28m

R19 564

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 17/9

12:39-8:35

2 stops36h 56m

Johannesburg OR Tambo

Wed 1/10

19:00-19:33

2 stops31h 33m

R19 582

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 17/9

9:30-8:35

2 stops40h 05m

Johannesburg OR Tambo

Wed 24/9

19:00-13:31

2 stops49h 31m

R19 582

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/10

22:20-11:50

1 stop30h 30m

Johannesburg OR Tambo

Sun 9/11

23:59-11:09

2 stops42h 10m

R19 830

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 12/9

9:13-17:45

2 stops25h 32m

Johannesburg OR Tambo

Mon 22/9

19:00-20:34

2 stops32h 34m

R22 377

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 8/2

9:13-18:00

2 stops25h 47m

Cape Town Intl

Thu 12/2

20:50-20:35

2 stops30h 45m

R25 402

Flights are sorted by cheapest return flights first.

Deals found on 27/8

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, September is the cheapest month in which you can book a flight from Panama City (average of R14 647). Flying from Panama City in August will prove the most costly (average of R41 446). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

When flying from Panama City check dates and pricing for the following: United Airlines. As it departs for the following popular destinations: Johannesburg.

United Airlines
United Airlines
From R1 014

What are popular destinations to fly to from Panama City?

From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (236 flights per day), San José (143 flights per day) and Miami (100 flights per day).

Quito Mariscal Sucr
Quito Mariscal Sucr
From R160
Bogotá El Dorado
Bogotá El Dorado
From R77
Madrid Barajas
Madrid Barajas
From R1 013

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at R1 362. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R77
Quito Mariscal Sucr
Quito Mariscal Sucr
From R160
Madrid Barajas
Madrid Barajas
From R1 013

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Get a feel of what it's like to fly with United Airlines from Panama City by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
8 944 reviews
Check prices

Crew

8,1

Overall

7,4

Entertainment

7,1

Food

6,6

Boarding

7,7

Comfort

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Oct 2024

EWR - DEN

Terribly delayed flight, missed ongoing flight, hotel very downmarket Food voucher not accepted in hotel
United Airlines
7,4
Good
8 944 reviews
United Airlines
7,4
Good
8 944 reviews
Check prices

Crew

8,1

Overall

7,4

Entertainment

7,1

Food

6,6

Boarding

7,7

Comfort

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Oct 2024

EWR - DEN

Terribly delayed flight, missed ongoing flight, hotel very downmarket Food voucher not accepted in hotel

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 August 2025.

  • What are the most popular destinations to fly to from Panama City?

    The most selected flight destinations from Panama City for the current month are Bogotá, Cartagena, Cali. While Bogotá, Cancún, Cartagena are the top choices made by travellers year-round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as R2 826 to Quito (prices may vary depending on the airline and departure time). On average, users have booked flights for R10 373 to fly from Panama City.

  • What is the cheapest month to fly from Panama City?

    September is currently the cheapest month to fly from Panama City. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama City?

    Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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