This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — JNB
Dec 4 — Dec 111
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Find flights from Panama City within your budget
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 4 November 2026. In the last 7 days, Cheapflights users made a total of 7 457 451 searches
Fly to
Route
Depart
Return
Price
Cheapest return flight
Fastest return journey
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Tue 15/12
9:19-12:10
Nonstop3h 51m
Mexico City Benito Juarez
Wed 31/12
0:00-1:00
Nonstop0h 00m
R3 406
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Thu 17/12
16:10-5:15
1 stop14h 05m
Mexico City Benito Juarez
Wed 31/12
0:00-1:00
Nonstop0h 00m
R5 782
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Sun 31/1
10:05-22:55
1 stop13h 50m
Mexico City Benito Juarez
Wed 31/12
0:00-1:00
Nonstop0h 00m
R5 849
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Fri 25/12
19:17-22:05
Nonstop3h 48m
Mexico City Benito Juarez
Wed 6/1
13:10-17:58
Nonstop3h 48m
R6 331
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Thu 3/12
21:26-0:15
Nonstop3h 49m
Mexico City Benito Juarez
Wed 9/12
3:25-8:07
Nonstop3h 42m
R6 414
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Thu 17/12
19:32-22:25
Nonstop3h 53m
Mexico City Benito Juarez
Thu 24/12
9:10-14:01
Nonstop3h 51m
R6 513
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Tue 2/2
9:22-12:10
Nonstop3h 48m
Mexico City Benito Juarez
Tue 2/3
23:55-4:27
Nonstop3h 32m
R6 597
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Mon 14/12
21:26-0:15
Nonstop3h 49m
Mexico City Benito Juarez
Mon 21/12
13:10-18:00
Nonstop3h 50m
R6 597
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Wed 16/12
21:26-0:15
Nonstop3h 49m
Mexico City Benito Juarez
Tue 5/1
15:30-20:17
Nonstop3h 47m
R6 696
Panama CityRio de Janeiro
PTY Panama City Tocumen Intl - SDU Rio de Janeiro Santos Dumont
PTYSDU
Panama City Tocumen Intl
Wed 18/11
10:05-11:05
2 stops23h 00m
Rio de Janeiro Santos Dumont
Wed 31/12
0:00-22:00
Nonstop0h 00m
R6 962
Flights are sorted by cheapest return flights first.
Deals found on 3/11
Showing 1-10 of 56 resultsSorted by cheapest first
1
2
3
...
6
Best time to book a flight from Panama City
Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
PTY-JNB
PTY-MEX
PTY-SDU
PTY-GRU
PTY-CPT
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Travel insights for flights from Panama City
Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.
PTY-JNB
PTY-MEX
PTY-SDU
PTY-GRU
PTY-CPT
What is the cheapest month to book a flight from Panama City?
Currently, May is the cheapest month in which you can book a flight from Panama City (average of R16 284). Flying from Panama City in June will prove the most costly (average of R35 708). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.
What are popular destinations to fly to from Panama City?
From Panama City you can expect to find greater availability for the following destinations: Sao Paulo (104 flights per day), Rio de Janeiro (102 flights per day) and Bogotá (72 flights per day).
Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 4 November 2026.
What are the most popular destinations to fly to from Panama City?
The most selected flight destinations from Panama City for the current month are Bogotá, Madrid, Guatemala City. While Bogotá, Madrid, Bocas del Toro are the top choices made by travellers year-round.
What is the cheapest flight from Panama City to anywhere?
Users have flown out of Panama City for as low as R11 087 to Sao Paulo Guarulhos Intl Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for R11 087 to fly from Panama City.
What is the cheapest premium economy flight from Panama City?
Premium economy can provide you with benefits such as more leg room and ideal seating locations without the price tag of a business class flight. Some of the cheapest premium economy flight options from Panama City are below: Panama City Tocumen Intl to Amsterdam from R26 600 Panama City Tocumen Intl to Newark Airport from R57 631
What is the cheapest month to fly from Panama City?
May is currently the cheapest month to fly from Panama City. At this moment in time June is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.
How does Cheapflights help users find flights from Panama City?
Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.
Why should you use Cheapflights to find cheap flight tickets from Panama City?
Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.
Can Cheapflights find flights from Panama City with no change fees?
Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Panama City become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!
See more FAQs
Fly with Cheapflights
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Panama City?
Deals for flights from Panama City are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.
Why should you use Cheapflights to find cheap flight tickets from Panama City?
Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.
Can Cheapflights find flights from Panama City with no change fees?
Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Panama City become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book With Flexibility
Our users can plan ahead with confidence and find flights with no change fees.
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
We value your privacy
Cheapflights and its partners wish to use cookies or similar technologies to store and/or access information on and about your device and process personal data such as your IP address, device identifiers etc., in order to improve your experience on the site, to analyse navigation, to offer and measure personalised advertising, and to facilitate sharing on social networks. We also allow the use of third-party cookies (including those from our advertising partners) on our sites.
By clicking 'Accept', you consent to your data being processed by 0 vendors on this web site for the purposes described in this notice. You can review the vendors and their individual processing purposes on the .
To review individual processing purposes and cookie categories, please click ’Select individual purposes’. You can review your choices and withdraw your consent at any time by clicking the ’Privacy Preferences’ link in the page side navigation.