R1 496+ Cheap flights from Knoxville
This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — JNB
Nov 7 — Nov 141
Find flights from Knoxville within your budget
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 8 October 2026. In the last 7 days, Cheapflights users made a total of 7 457 451 searches
Fly to
Route
Depart
Return
Cheapest return flight
KnoxvilleWashington, D.C.
TYS Knoxville McGhee Tyson - DCA Washington, D.C. Reagan-National
TYSDCA
Knoxville McGhee Tyson
Sat 14/11
14:50-19:55
1 stop5h 05m
Washington, D.C. Reagan-National
Wed 31/12
0:00-0:00
Nonstop0h 00m
R1 595
KnoxvilleDetroit
TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County
TYSDTW
Knoxville McGhee Tyson
Mon 7/12
17:15-21:20
1 stop4h 05m
Detroit Metropolitan Wayne County
Wed 31/12
0:00-0:00
Nonstop0h 00m
R2 094
KnoxvilleDetroit
TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County
TYSDTW
Knoxville McGhee Tyson
Thu 5/11
12:50-20:05
1 stop7h 15m
Detroit Metropolitan Wayne County
Wed 31/12
0:00-0:00
Nonstop0h 00m
R2 094
KnoxvilleDetroit
TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County
TYSDTW
Knoxville McGhee Tyson
Sat 5/12
8:15-13:00
1 stop4h 45m
Detroit Metropolitan Wayne County
Wed 31/12
0:00-0:00
Nonstop0h 00m
R2 094
KnoxvilleDetroit
TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County
TYSDTW
Knoxville McGhee Tyson
Sat 31/10
6:40-15:50
2 stops9h 10m
Detroit Metropolitan Wayne County
Wed 31/12
0:00-0:00
Nonstop0h 00m
R2 210
KnoxvilleDetroit
TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County
TYSDTW
Knoxville McGhee Tyson
Tue 5/1
7:55-21:20
2 stops13h 25m
Detroit Metropolitan Wayne County
Wed 31/12
0:00-0:00
Nonstop0h 00m
R2 277
KnoxvilleWashington, D.C.
TYS Knoxville McGhee Tyson - DCA Washington, D.C. Reagan-National
TYSDCA
Knoxville McGhee Tyson
Sun 22/11
19:25-22:55
1 stop3h 30m
Washington, D.C. Reagan-National
Wed 31/12
0:00-0:00
Nonstop0h 00m
R2 891
KnoxvilleWashington, D.C.
TYS Knoxville McGhee Tyson - DCA Washington, D.C. Reagan-National
TYSDCA
Knoxville McGhee Tyson
Thu 3/12
14:40-22:00
2 stops7h 20m
Washington, D.C. Reagan-National
Tue 8/12
6:05-12:20
1 stop6h 15m
R3 058
KnoxvilleWashington, D.C.
TYS Knoxville McGhee Tyson - DCA Washington, D.C. Reagan-National
TYSDCA
Knoxville McGhee Tyson
Fri 30/10
19:25-23:05
1 stop3h 40m
Washington, D.C. Reagan-National
Mon 2/11
15:35-20:30
1 stop4h 55m
R3 589
KnoxvilleWashington, D.C.
TYS Knoxville McGhee Tyson - DCA Washington, D.C. Reagan-National
TYSDCA
Knoxville McGhee Tyson
Tue 3/11
5:40-11:26
1 stop5h 46m
Washington, D.C. Reagan-National
Wed 31/12
0:00-0:00
Nonstop0h 00m
R3 706
Showing 1-10 of 40 resultsSorted by cheapest first
Best time to book a flight from Knoxville
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TYS-JNB
TYS-DCA
TYS-DTW
TYS-AMS
TYS-BOM
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Travel insights for flights from Knoxville
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TYS-JNB
TYS-DCA
TYS-DTW
TYS-AMS
TYS-BOM
No data available for this route at this time. Please check back soon.
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