R3 678+ Cheap flights from Knoxville

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — JNB
Jan 27 — Feb 31
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on 28 December 2025.

Sun 22/211:13TYS - JNB
2 stops37h 22mMultiple Airlines
Tue 3/322:00JNB - TYS
2 stops30h 28mMultiple Airlines
Deal found 26/12R20 585
Mon 26/117:15TYS - JNB
2 stops31h 20mAmerican Airlines
Tue 3/219:35JNB - TYS
2 stops32h 21mAmerican Airlines
Deal found 28/12R20 851
Fri 23/119:11TYS - JNB
2 stops32h 14mAmerican Airlines
Fri 30/122:00JNB - TYS
2 stops30h 54mAmerican Airlines
Deal found 26/12R21 001
Sun 22/26:45TYS - JNB
2 stops30h 25mEthiopian Air
Tue 3/314:30JNB - TYS
3 stops31h 45mEthiopian Air
Deal found 26/12R24 113
Thu 5/217:14TYS - JNB
2 stops58h 11mBritish Airways
Sun 8/222:00JNB - TYS
2 stops29h 56mBritish Airways
Deal found 25/12R24 262
Thu 5/214:25TYS - JNB
3 stops30h 30mEthiopian Air
Sun 8/214:30JNB - TYS
3 stops31h 19mEthiopian Air
Deal found 27/12R25 727
Mon 26/114:25TYS - JNB
3 stops37h 05mAir Canada
Tue 3/220:15JNB - TYS
3 stops45h 42mAir Canada
Deal found 28/12R26 026
Wed 7/117:17TYS - JNB
2 stops34h 08mBritish Airways
Thu 29/122:00JNB - TYS
2 stops31h 09mBritish Airways
Deal found 28/12R29 987
Wed 7/114:25TYS - JNB
3 stops30h 30mEthiopian Air
Thu 29/123:00JNB - TYS
3 stops46h 49mEthiopian Air
Deal found 28/12R31 235
Fri 23/17:15TYS - JNB
3 stops33h 00mMultiple Airlines
Fri 30/113:45JNB - TYS
2 stops39h 09mMultiple Airlines
Deal found 26/12R31 568
Sun 1/218:51TYS - CPT
2 stops56h 39mQatar Airways
Thu 5/212:35CPT - TYS
2 stops40h 34mQatar Airways
Deal found 27/12R32 849

Find flights from Knoxville within your budget

 
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 28 December 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 22/2

11:13-7:35

2 stops37h 22m

Johannesburg OR Tambo

Tue 3/3

22:00-21:28

2 stops30h 28m

R20 585

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 26/1

17:15-7:35

2 stops31h 20m

Johannesburg OR Tambo

Tue 3/2

19:35-20:56

2 stops32h 21m

R20 851

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 23/1

19:11-10:25

2 stops32h 14m

Johannesburg OR Tambo

Fri 30/1

22:00-21:54

2 stops30h 54m

R21 001

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 5/2

17:14-10:25

2 stops58h 11m

Johannesburg OR Tambo

Sun 8/2

22:00-20:56

2 stops29h 56m

R24 262

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 5/2

14:25-3:55

3 stops30h 30m

Johannesburg OR Tambo

Sun 8/2

14:30-14:49

3 stops31h 19m

R25 727

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 26/1

14:25-10:30

3 stops37h 05m

Johannesburg OR Tambo

Tue 3/2

20:15-10:57

3 stops45h 42m

R26 026

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 7/1

17:17-10:25

2 stops34h 08m

Johannesburg OR Tambo

Thu 29/1

22:00-22:09

2 stops31h 09m

R29 987

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 8/1

17:14-10:25

2 stops34h 11m

Johannesburg OR Tambo

Thu 29/1

19:35-18:46

2 stops30h 11m

R29 987

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 7/1

14:25-3:55

3 stops30h 30m

Johannesburg OR Tambo

Thu 29/1

23:00-14:49

3 stops46h 49m

R31 235

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sun 1/2

18:51-10:30

2 stops56h 39m

Cape Town Intl

Thu 5/2

12:35-22:09

2 stops40h 34m

R32 849

Flights are sorted by cheapest return flights first.

Deals found on 26/12

Showing 1-10 of 16 results
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Estimated return price
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Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 December 2025.

  • What are the most popular destinations to fly to from Knoxville?

    The most selected flight destinations from Knoxville for the current month are Denver, Fort Lauderdale, Dallas/Fort Worth Airport. While Denver, Fort Lauderdale, Boston are the top choices made by travellers year-round.

  • How does Cheapflights help users find flights from Knoxville?

    Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Knoxville?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

  • Can Cheapflights find flights from Knoxville with no change fees?

    Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

    Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Knoxville?

Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Knoxville?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

Can Cheapflights find flights from Knoxville with no change fees?

Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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