R3 021+ Cheap flights from Knoxville

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — JNB
Jan 2 — Jan 91
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on 3 December 2025.

Fri 23/117:15TYS - JNB
2 stops34h 10mAmerican Airlines
Sun 25/122:00JNB - TYS
2 stops25h 49mAmerican Airlines
Deal found 1/12R21 061
Sat 17/117:14TYS - CPT
2 stops34h 06mAmerican Airlines
Sat 24/120:50CPT - TYS
2 stops28h 56mAmerican Airlines
Deal found 3/12R23 365
Fri 23/117:15TYS - JNB
2 stops34h 10mBritish Airways
Sun 25/122:00JNB - TYS
2 stops27h 46mBritish Airways
Deal found 2/12R24 747
Thu 22/119:11TYS - CPT
2 stops29h 54mAmerican Airlines
Mon 26/118:55CPT - TYS
2 stops33h 26mAmerican Airlines
Deal found 1/12R25 072
Thu 22/117:14TYS - CPT
2 stops59h 56mBritish Airways
Mon 26/122:10CPT - TYS
2 stops30h 11mBritish Airways
Deal found 2/12R26 300
Sat 16/55:50TYS - JNB
2 stops25h 15mEthiopian Air
Fri 29/514:30JNB - TYS
3 stops30h 12mEthiopian Air
Deal found 1/12R27 939
Sat 17/116:45TYS - CPT
1 stop19h 30mDelta
Sat 24/18:00CPT - TYS
2 stops43h 00mDelta
Deal found 3/12R30 106
Sat 17/116:16TYS - CPT
2 stops42h 14mMultiple Airlines
Sat 24/16:05CPT - TYS
3 stops42h 48mMultiple Airlines
Deal found 3/12R30 994
Sat 16/514:30TYS - JNB
1 stop23h 10mDelta
Fri 29/518:10JNB - TYS
2 stops33h 18mDelta
Deal found 1/12R37 343
Thu 22/111:58TYS - CPT
1 stop24h 17mVirgin Atlantic
Mon 26/121:30CPT - TYS
1 stop27h 26mVirgin Atlantic
Deal found 30/11R38 776
Fri 23/111:58TYS - JNB
1 stop24h 02mVirgin Atlantic
Sun 25/121:55JNB - TYS
1 stop29h 05mVirgin Atlantic
Deal found 1/12R38 776
Thu 22/19:30TYS - CPT
1 stop23h 40mUnited Airlines
Mon 26/120:50CPT - TYS
2 stops27h 03mUnited Airlines
Deal found 30/11R38 845

Find flights from Knoxville within your budget

 
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 3 December 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 16/5

18:22-9:25

2 stops33h 03m

Johannesburg OR Tambo

Fri 29/5

21:15-17:33

2 stops26h 18m

R21 061

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 23/1

17:15-10:25

2 stops34h 10m

Johannesburg OR Tambo

Sun 25/1

22:00-16:49

2 stops25h 49m

R21 061

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 23/1

17:36-10:25

2 stops33h 49m

Johannesburg OR Tambo

Mon 26/1

22:00-20:56

2 stops29h 56m

R21 061

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sat 17/1

17:14-10:20

2 stops34h 06m

Cape Town Intl

Sat 24/1

20:50-18:46

2 stops28h 56m

R23 365

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 23/1

17:15-10:25

2 stops34h 10m

Johannesburg OR Tambo

Sun 25/1

22:00-18:46

2 stops27h 46m

R24 747

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 22/1

17:15-10:20

2 stops34h 05m

Cape Town Intl

Mon 26/1

22:10-22:09

2 stops30h 59m

R25 072

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 22/1

17:14-12:10

2 stops59h 56m

Cape Town Intl

Mon 26/1

22:10-21:21

2 stops30h 11m

R26 300

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 16/5

5:50-13:05

2 stops25h 15m

Johannesburg OR Tambo

Fri 29/5

14:30-14:42

3 stops30h 12m

R27 939

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sat 17/1

16:45-19:15

1 stop19h 30m

Cape Town Intl

Sat 24/1

8:00-20:00

2 stops43h 00m

R30 106

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sat 17/1

16:16-17:30

2 stops42h 14m

Cape Town Intl

Sat 24/1

6:05-17:53

3 stops42h 48m

R30 994

Flights are sorted by cheapest return flights first.

Deals found on 1/12

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Estimated return price
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Travel insights for flights from Knoxville

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Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 3 December 2025.

  • What are the most popular destinations to fly to from Knoxville?

    The most selected flight destinations from Knoxville for the current month are Denver, Fort Lauderdale, Dallas/Fort Worth Airport. While Denver, Fort Lauderdale, Boston are the top choices made by travellers year-round.

  • How does Cheapflights help users find flights from Knoxville?

    Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Knoxville?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

  • Can Cheapflights find flights from Knoxville with no change fees?

    Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

    Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Knoxville?

Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Knoxville?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

Can Cheapflights find flights from Knoxville with no change fees?

Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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