R3 121+ Cheap flights from Knoxville

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — JNB
Feb 9 — Feb 161
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on 10 January 2026.

Sun 22/214:49TYS - JNB
2 stops33h 46mAmerican Airlines
Sun 1/322:00JNB - TYS
2 stops27h 13mAmerican Airlines
Deal found 8/1R18 778
Mon 1/618:30TYS - JNB
2 stops32h 55mAmerican Airlines
Sat 13/619:25JNB - TYS
2 stops28h 46mAmerican Airlines
Deal found 9/1R22 097
Thu 5/217:14TYS - JNB
2 stops31h 21mBritish Airways
Sun 8/219:35JNB - TYS
2 stops30h 11mBritish Airways
Deal found 7/1R23 154
Thu 5/214:25TYS - JNB
2 stops39h 40mEthiopian Air
Sun 8/214:30JNB - TYS
3 stops31h 19mEthiopian Air
Deal found 7/1R25 664
Sun 22/29:40TYS - JNB
3 stops40h 50mAir Canada
Sun 1/320:15JNB - TYS
3 stops45h 34mAir Canada
Deal found 8/1R26 639
Mon 1/65:50TYS - JNB
2 stops25h 15mEthiopian Air
Sat 13/614:30JNB - TYS
3 stops30h 12mEthiopian Air
Deal found 9/1R27 283
Mon 1/617:40TYS - JNB
1 stop20h 00mDelta
Sat 13/621:55JNB - TYS
1 stop21h 30mDelta
Deal found 9/1R34 252
Sun 1/212:21TYS - CPT
2 stops39h 09mQatar Airways
Thu 5/212:35CPT - TYS
2 stops41h 12mQatar Airways
Deal found 7/1R36 052

Find flights from Knoxville within your budget

 
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 January 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 22/2

14:49-7:35

2 stops33h 46m

Johannesburg OR Tambo

Sun 1/3

22:00-18:13

2 stops27h 13m

R18 778

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 1/6

18:30-9:25

2 stops32h 55m

Johannesburg OR Tambo

Sat 13/6

19:25-18:11

2 stops28h 46m

R22 097

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 5/2

17:15-7:35

2 stops31h 20m

Johannesburg OR Tambo

Sun 8/2

22:00-18:46

2 stops27h 46m

R23 154

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 5/2

14:25-13:05

2 stops39h 40m

Johannesburg OR Tambo

Sun 8/2

14:30-14:49

3 stops31h 19m

R25 664

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 1/6

5:50-13:05

2 stops25h 15m

Johannesburg OR Tambo

Sat 13/6

14:30-14:42

3 stops30h 12m

R27 283

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 1/6

17:40-19:40

1 stop20h 00m

Johannesburg OR Tambo

Sat 13/6

21:55-13:25

1 stop21h 30m

R34 252

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 1/6

19:20-19:40

1 stop18h 20m

Johannesburg OR Tambo

Sat 13/6

21:55-16:12

2 stops24h 17m

R34 500

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 22/2

12:21-15:35

2 stops44h 14m

Johannesburg OR Tambo

Sun 1/3

14:30-15:15

3 stops31h 45m

R34 599

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sun 1/2

12:21-10:30

2 stops39h 09m

Cape Town Intl

Thu 5/2

12:35-22:47

2 stops41h 12m

R36 052

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sun 8/2

13:39-9:45

3 stops37h 06m

R11 874

Flights are sorted by cheapest return flights first.

Deals found on 9/1

Showing 1-10 of 15 results
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Estimated return price
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Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 January 2026.

  • What are the most popular destinations to fly to from Knoxville?

    The most selected flight destinations from Knoxville for the current month are Fort Lauderdale, Denver, Newark Airport. While Denver, Fort Lauderdale, Boston are the top choices made by travellers year-round.

  • How does Cheapflights help users find flights from Knoxville?

    Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Knoxville?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

  • Can Cheapflights find flights from Knoxville with no change fees?

    Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

    Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Knoxville?

Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Knoxville?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

Can Cheapflights find flights from Knoxville with no change fees?

Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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