R3 223+ Cheap flights from Knoxville

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — JNB
Aug 24 — Aug 311
1 adult

Find flights from Knoxville

Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on 19 August 2025.

Wed 29/1017:17TYS - CPT
2 stops32h 48mAmerican Airlines
Sat 15/1122:10CPT - TYS
2 stops26h 51mAmerican Airlines
Deal found 17/8R18 825
Sun 26/1017:37TYS - CPT
2 stops32h 28mBritish Airways
Sun 16/1120:35CPT - TYS
2 stops29h 19mBritish Airways
Deal found 17/8R21 678
Fri 31/1015:03TYS - CPT
2 stops39h 07mBritish Airways
Wed 12/1120:35CPT - TYS
2 stops31h 49mBritish Airways
Deal found 17/8R22 348
Sat 1/1118:11TYS - CPT
2 stops55h 54mBritish Airways
Mon 17/1122:10CPT - TYS
2 stops27h 44mBritish Airways
Deal found 17/8R22 436
Wed 17/96:10TYS - JNB
2 stops45h 25mQatar Airways
Wed 24/920:25JNB - TYS
2 stops33h 25mQatar Airways
Deal found 18/8R22 576
Thu 30/1017:37TYS - CPT
2 stops32h 28mBritish Airways
Sun 16/1120:35CPT - TYS
2 stops29h 19mBritish Airways
Deal found 17/8R23 228
Tue 30/917:43TYS - JNB
2 stops33h 42mAmerican Airlines
Fri 10/1019:25JNB - TYS
2 stops28h 07mAmerican Airlines
Deal found 18/8R24 161
Wed 17/95:45TYS - JNB
2 stops25h 20mEthiopian Air
Wed 24/914:30JNB - TYS
3 stops30h 15mEthiopian Air
Deal found 18/8R25 817
Thu 30/1014:25TYS - CPT
1 stop18h 55mUnited Airlines
Sun 16/1120:50CPT - TYS
1 stop20h 58mUnited Airlines
Deal found 17/8R26 873
Wed 29/105:45TYS - CPT
2 stops26h 50mEthiopian Air
Sat 15/1113:50CPT - TYS
3 stops31h 53mEthiopian Air
Deal found 17/8R28 000
Thu 30/1014:25TYS - CPT
1 stop18h 55mUnited Airlines
Fri 14/1120:50CPT - TYS
1 stop20h 58mUnited Airlines
Deal found 17/8R29 075
Fri 12/1219:25TYS - JNB
2 stops28h 40mLufthansa
Sun 18/119:45JNB - TYS
2 stops29h 57mLufthansa
Deal found 17/8R29 180

Find flights from Knoxville within your budget

 
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 19 August 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 29/10

17:17-8:05

2 stops32h 48m

Cape Town Intl

Sat 15/11

22:10-18:01

2 stops26h 51m

R18 825

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 29/10

15:03-8:05

2 stops35h 02m

Cape Town Intl

Mon 17/11

22:10-21:24

2 stops30h 14m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Mon 27/10

15:03-12:10

2 stops39h 07m

Cape Town Intl

Tue 18/11

20:50-18:54

2 stops29h 04m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sun 26/10

17:37-8:05

2 stops32h 28m

Cape Town Intl

Mon 17/11

22:10-18:54

2 stops27h 44m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Tue 28/10

17:37-12:10

2 stops36h 33m

Cape Town Intl

Tue 18/11

20:50-18:54

2 stops29h 04m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 29/10

17:37-12:10

2 stops36h 33m

Cape Town Intl

Sun 16/11

20:35-21:24

2 stops31h 49m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 29/10

17:37-8:05

2 stops32h 28m

Cape Town Intl

Thu 13/11

22:10-22:51

2 stops31h 41m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Mon 27/10

17:37-8:05

2 stops32h 28m

Cape Town Intl

Sun 16/11

18:55-18:54

2 stops30h 59m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 29/10

17:37-8:05

2 stops32h 28m

Cape Town Intl

Wed 12/11

18:55-22:54

2 stops34h 59m

R21 678

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Tue 28/10

15:03-12:10

2 stops39h 07m

Cape Town Intl

Thu 13/11

22:10-18:54

2 stops27h 44m

R21 678

Flights are sorted by cheapest return flights first.

Deals found on 17/8

Showing 1-10 of 23 results
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Best time to book a flight from Knoxville

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Estimated return price
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Travel insights for flights from Knoxville

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Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 19 August 2025.

  • What are the most popular destinations to fly to from Knoxville?

    The most selected flight destinations from Knoxville for the current month are Denver, Chicago, Boston. While Denver, Fort Lauderdale, Chicago are the top choices made by travellers year-round.

  • How does Cheapflights help users find flights from Knoxville?

    Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Knoxville?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

  • Can Cheapflights find flights from Knoxville with no change fees?

    Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

    Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Knoxville?

Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Knoxville?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

Can Cheapflights find flights from Knoxville with no change fees?

Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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