R3 016+ Cheap flights from Knoxville

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — CPT
Mar 12 — Mar 191
1 adult
1 adult, Economy, 0 bags

Find flights from Knoxville

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Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on 10 February 2026.

Tue 24/316:29
TYS
-
JNB
2 stops41h 06m
Qatar Airways
Tue 31/314:45
JNB
-
TYS
2 stops39h 14m
Qatar Airways
Deal found 7/2R21 844
Wed 4/316:02
TYS
-
JNB
2 stops32h 33m
British Airways
Sun 8/319:35
JNB
-
TYS
2 stops30h 30m
British Airways
Deal found 8/2R23 216
Wed 4/311:42
TYS
-
JNB
2 stops33h 13m
Qatar Airways
Sun 8/320:30
JNB
-
TYS
2 stops30h 54m
Qatar Airways
Deal found 9/2R23 998
Mon 16/318:21
TYS
-
CPT
2 stops41h 04m
Qatar Airways
Thu 19/312:35
CPT
-
TYS
2 stops34h 56m
Qatar Airways
Deal found 7/2R26 822
Tue 24/317:10
TYS
-
JNB
1 stop19h 50m
Delta
Tue 31/323:15
JNB
-
TYS
2 stops27h 51m
Delta
Deal found 7/2R33 763
Tue 24/314:21
TYS
-
JNB
3 stops38h 09m
Air Canada
Tue 31/319:25
JNB
-
TYS
3 stops45h 25m
Air Canada
Deal found 7/2R34 385
Tue 24/312:03
TYS
-
JNB
1 stop24h 57m
Virgin Atlantic
Tue 31/321:55
JNB
-
TYS
1 stop24h 11m
Virgin Atlantic
Deal found 7/2R36 300
Mon 16/314:21
TYS
-
CPT
2 stops41h 24m
Ethiopian Air
Thu 19/313:50
CPT
-
TYS
3 stops35h 39m
Ethiopian Air
Deal found 9/2R37 305
Mon 16/39:40
TYS
-
CPT
1 stop23h 25m
United Airlines
Thu 19/320:50
CPT
-
TYS
2 stops25h 55m
United Airlines
Deal found 9/2R39 555
Sat 28/311:42
TYS
-
JNB
2 stops37h 18m
British Airways
Sat 4/419:25
JNB
-
TYS
2 stops27h 51m
British Airways
Deal found 7/2R40 736
Mon 16/317:10
TYS
-
CPT
1 stop20h 05m
Delta
Thu 19/321:30
CPT
-
TYS
1 stop23h 02m
Delta
Deal found 9/2R50 661
Sat 28/310:04
TYS
-
JNB
1 stop27h 36m
Delta
Sat 4/420:25
JNB
-
TYS
2 stops31h 26m
Delta
Deal found 9/2R75 265

Find flights from Knoxville within your budget

 
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 10 February 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 24/3

16:29-15:35

2 stops41h 06m

Johannesburg OR Tambo

Tue 31/3

14:45-23:59

2 stops39h 14m

R21 844

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 4/3

16:02-7:35

2 stops32h 33m

Johannesburg OR Tambo

Sun 8/3

22:00-21:05

2 stops29h 05m

R23 216

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 4/3

11:42-3:55

2 stops33h 13m

Johannesburg OR Tambo

Sun 8/3

20:30-21:24

2 stops30h 54m

R23 998

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 24/3

14:21-10:30

3 stops38h 09m

Johannesburg OR Tambo

Tue 31/3

19:25-10:50

3 stops45h 25m

R34 385

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 24/3

12:03-19:00

1 stop24h 57m

Johannesburg OR Tambo

Tue 31/3

21:55-16:06

1 stop24h 11m

R36 300

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Mon 16/3

14:21-13:45

2 stops41h 24m

Cape Town Intl

Thu 19/3

13:50-19:29

3 stops35h 39m

R37 305

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Mon 16/3

7:00-15:05

3 stops26h 05m

Cape Town Intl

Thu 19/3

20:50-16:45

2 stops25h 55m

R39 555

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 28/3

11:42-7:00

2 stops37h 18m

Johannesburg OR Tambo

Sat 4/4

19:25-17:16

2 stops27h 51m

R40 736

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Mon 16/3

12:03-19:15

1 stop25h 12m

Cape Town Intl

Thu 19/3

21:30-19:27

1 stop27h 57m

R50 661

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 28/3

10:04-19:40

1 stop27h 36m

Johannesburg OR Tambo

Sat 4/4

20:25-21:51

2 stops31h 26m

R75 265

Flights are sorted by cheapest return flights first.

Deals found on 7/2

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Estimated return price
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Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 10 February 2026.

  • What are the most popular destinations to fly to from Knoxville?

    The most selected flight destinations from Knoxville for the current month are Fort Lauderdale, Las Vegas, Denver. While Denver, Las Vegas, Fort Lauderdale are the top choices made by travellers year-round.

  • How does Cheapflights help users find flights from Knoxville?

    Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Knoxville?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

  • Can Cheapflights find flights from Knoxville with no change fees?

    Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

    Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Knoxville?

Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Knoxville?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

Can Cheapflights find flights from Knoxville with no change fees?

Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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