R3 168+ Cheap flights from Knoxville

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — JNB
Jan 20 — Jan 271
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on 21 December 2025.

Tue 3/216:00TYS - JNB
2 stops32h 35mAmerican Airlines
Tue 10/222:00JNB - TYS
2 stops31h 54mAmerican Airlines
Deal found 20/12R20 720
Mon 19/117:14TYS - JNB
2 stops34h 11mAmerican Airlines
Mon 26/122:00JNB - TYS
2 stops31h 54mAmerican Airlines
Deal found 19/12R21 139
Thu 5/214:37TYS - CPT
1 stop21h 38mDelta
Sun 8/221:30CPT - TYS
1 stop23h 20mDelta
Deal found 20/12R23 855
Thu 5/217:14TYS - JNB
2 stops58h 11mBritish Airways
Mon 9/219:35JNB - TYS
2 stops32h 21mBritish Airways
Deal found 20/12R24 441
Thu 5/214:25TYS - CPT
2 stops41h 10mEthiopian Air
Sun 8/213:50CPT - TYS
3 stops31h 59mEthiopian Air
Deal found 20/12R25 011
Mon 2/213:59TYS - JNB
2 stops21h 36mUnited Airlines
Mon 9/222:00JNB - TYS
2 stops27h 05mUnited Airlines
Deal found 19/12R25 263
Mon 19/114:25TYS - JNB
3 stops37h 05mAir Canada
Mon 26/120:15JNB - TYS
3 stops45h 42mAir Canada
Deal found 19/12R26 369
Tue 3/214:25TYS - JNB
3 stops37h 05mAir Canada
Tue 10/220:15JNB - TYS
3 stops45h 34mAir Canada
Deal found 20/12R26 419
Thu 5/214:25TYS - JNB
3 stops30h 30mEthiopian Air
Mon 9/214:30JNB - TYS
3 stops31h 19mEthiopian Air
Deal found 20/12R27 174
Mon 19/114:25TYS - JNB
2 stops39h 40mEthiopian Air
Mon 26/114:30JNB - TYS
3 stops31h 19mEthiopian Air
Deal found 19/12R27 794
Tue 3/26:20TYS - JNB
2 stops43h 20mMultiple Airlines
Tue 10/214:30JNB - TYS
3 stops31h 19mMultiple Airlines
Deal found 20/12R31 616
Thu 5/27:54TYS - CPT
2 stops43h 36mQatar Airways
Sun 8/212:35CPT - TYS
2 stops34h 11mQatar Airways
Deal found 20/12R33 846

Find flights from Knoxville within your budget

 
Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 21 December 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 19/1

17:14-10:25

2 stops34h 11m

Johannesburg OR Tambo

Mon 26/1

22:00-22:54

2 stops31h 54m

R21 139

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 5/2

14:37-19:15

1 stop21h 38m

Cape Town Intl

Sun 8/2

21:30-13:50

1 stop23h 20m

R23 855

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 5/2

17:14-10:25

2 stops58h 11m

Johannesburg OR Tambo

Mon 9/2

19:35-21:21

2 stops32h 46m

R24 441

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 5/2

14:25-14:35

2 stops41h 10m

Cape Town Intl

Sun 8/2

13:50-14:49

3 stops31h 59m

R25 011

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 19/1

14:25-10:30

3 stops37h 05m

Johannesburg OR Tambo

Mon 26/1

20:15-10:57

3 stops45h 42m

R26 369

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 3/2

14:25-10:30

3 stops37h 05m

Johannesburg OR Tambo

Tue 10/2

20:15-10:49

3 stops45h 34m

R26 419

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 5/2

14:25-3:55

3 stops30h 30m

Johannesburg OR Tambo

Mon 9/2

14:30-14:49

3 stops31h 19m

R27 174

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 19/1

14:25-13:05

2 stops39h 40m

Johannesburg OR Tambo

Mon 26/1

14:30-14:49

3 stops31h 19m

R27 794

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 3/2

6:20-8:40

2 stops43h 20m

Johannesburg OR Tambo

Tue 10/2

14:30-14:49

3 stops31h 19m

R31 616

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 5/2

7:54-10:30

2 stops43h 36m

Cape Town Intl

Sun 8/2

12:35-22:47

2 stops41h 12m

R33 846

Flights are sorted by cheapest return flights first.

Deals found on 19/12

Showing 1-10 of 14 results
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Estimated return price
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Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 December 2025.

  • What are the most popular destinations to fly to from Knoxville?

    The most selected flight destinations from Knoxville for the current month are Denver, Fort Lauderdale, Dallas/Fort Worth Airport. While Denver, Fort Lauderdale, Boston are the top choices made by travellers year-round.

  • How does Cheapflights help users find flights from Knoxville?

    Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Knoxville?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

  • Can Cheapflights find flights from Knoxville with no change fees?

    Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

    Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Knoxville?

Cheapflights makes it easy to find flights from Knoxville by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Knoxville?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Knoxville.

Can Cheapflights find flights from Knoxville with no change fees?

Yes, we can. To see specific flights from Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Knoxville become cheaper?

Of course! You can now track prices for flights from Knoxville and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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