R5 540+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Dec 23 — Dec 301
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 23 November 2025.

Good round-trip deal

R17 594 or less

Good one-way deal

R1 337 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

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Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 23 November 2025.

Wed 1/422:29PTY - CPT
1 stop33h 51mUnited Airlines
Tue 14/420:00CPT - PTY
2 stops27h 12mUnited Airlines
Deal found 22/11R17 297
Wed 4/219:20PTY - CPT
2 stops37h 50mUnited Airlines
Sun 8/220:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 22/11R17 454
Mon 9/29:11PTY - CPT
1 stop23h 59mUnited Airlines
Mon 23/220:50CPT - PTY
2 stops29h 48mUnited Airlines
Deal found 23/11R18 218
Thu 5/29:11PTY - JNB
2 stops28h 19mUnited Airlines
Mon 9/219:45JNB - PTY
2 stops31h 50mUnited Airlines
Deal found 22/11R18 496
Mon 13/418:50PTY - CPT
1 stop28h 00mKLM
Mon 27/423:15CPT - PTY
1 stop24h 35mKLM
Deal found 23/11R18 565
Mon 13/420:10PTY - JNB
1 stop31h 25mTurkish Airlines
Mon 20/418:00JNB - PTY
1 stop31h 30mTurkish Airlines
Deal found 23/11R19 190
Mon 11/518:41PTY - CPT
2 stops55h 49mUnited Airlines
Sat 23/519:50CPT - PTY
2 stops45h 43mUnited Airlines
Deal found 23/11R20 007
Mon 9/221:45PTY - CPT
1 stop31h 05mTurkish Airlines
Mon 23/217:15CPT - PTY
1 stop30h 50mTurkish Airlines
Deal found 23/11R21 257
Wed 7/18:55PTY - CPT
2 stops48h 15mUnited Airlines
Wed 14/120:50CPT - PTY
2 stops44h 35mUnited Airlines
Deal found 22/11R21 934
Wed 1/422:15PTY - JNB
1 stop29h 20mTurkish Airlines
Fri 3/418:00JNB - PTY
1 stop33h 20mTurkish Airlines
Deal found 23/11R24 001
Wed 1/48:16PTY - JNB
2 stops27h 14mUnited Airlines
Fri 3/419:00JNB - PTY
2 stops56h 35mUnited Airlines
Deal found 23/11R25 668
Mon 13/48:10PTY - JNB
2 stops27h 20mUnited Airlines
Mon 20/422:00JNB - PTY
2 stops39h 37mUnited Airlines
Deal found 23/11R28 898

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 23 November 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 16/3

9:11-15:05

1 stop22h 54m

Cape Town Intl

Sun 22/3

20:50-6:13

1 stop40h 23m

R17 297

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 13/4

9:11-15:20

1 stop23h 09m

Cape Town Intl

Mon 27/4

19:50-10:33

2 stops45h 43m

R17 297

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 1/4

22:29-15:20

1 stop33h 51m

Cape Town Intl

Tue 14/4

20:00-13:31

1 stop24h 31m

R17 297

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 24/1

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Sat 7/2

22:00-10:46

2 stops43h 46m

R17 297

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

8:16-18:00

2 stops26h 44m

Cape Town Intl

Sun 8/2

20:50-13:31

1 stop23h 41m

R17 454

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 5/2

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Mon 9/2

19:45-20:35

2 stops31h 50m

R18 391

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

20:10-10:35

1 stop31h 25m

Johannesburg OR Tambo

Mon 20/4

18:00-18:30

1 stop31h 30m

R19 190

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 5/2

18:45-10:50

1 stop33h 05m

Johannesburg OR Tambo

Mon 9/2

19:05-17:05

2 stops29h 00m

R21 517

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 1/4

22:15-10:35

1 stop29h 20m

Johannesburg OR Tambo

Fri 3/4

18:00-20:20

1 stop33h 20m

R24 001

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 6/5

3:20-9:30

2 stops47h 10m

R9 395

Flights are sorted by cheapest return flights first.

Deals found on 21/11

Showing 1-10 of 18 results
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2

Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Bogotá El Dorado, with prices starting at R1 337. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R1 337
Panama City Tocumen Intl
Panama City Tocumen Intl
From R1 909
Madrid Barajas
Madrid Barajas
From R17 594

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 23 November 2025.

  • How does Cheapflights help users find flights from Panama?

    Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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