R4 047+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Sep 13 — Sep 201
1 adult
1 adult, Economy, 0 bags

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 14 August 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Fri 23/10

9:45-17:10

1 stop24h 25m

Cape Town Intl

Sat 7/11

20:50-6:37

2 stops40h 47m

R15 555

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sat 26/9

9:45-17:20

2 stops48h 35m

Cape Town Intl

Sat 3/10

19:50-10:33

2 stops45h 43m

R15 733

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sat 21/11

22:29-18:35

2 stops37h 06m

Johannesburg OR Tambo

Sat 26/12

22:00-20:27

2 stops29h 27m

R19 019

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Thu 5/11

18:48-16:10

2 stops62h 22m

Cape Town Intl

Mon 30/11

19:10-6:13

2 stops42h 03m

R19 909

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 11/12

16:41-9:40

2 stops57h 59m

Johannesburg OR Tambo

Fri 15/1

19:45-20:31

2 stops31h 46m

R20 832

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 11/12

22:29-9:40

2 stops52h 11m

Johannesburg OR Tambo

Sun 17/1

19:45-20:38

2 stops31h 53m

R22 369

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 2/11

9:11-18:35

2 stops26h 24m

Johannesburg OR Tambo

Sat 7/11

22:00-10:05

2 stops43h 05m

R22 466
Fastest return journey

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sun 24/1

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Thu 28/1

22:00-20:02

1 stop29h 02m

R22 547

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sun 24/1

18:50-11:00

1 stop33h 10m

Johannesburg OR Tambo

Thu 28/1

18:50-17:10

2 stops29h 20m

R22 580

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sat 26/9

12:04-17:10

3 stops46h 06m

Cape Town Intl

Wed 30/9

17:55-19:31

2 stops32h 36m

R24 279

Flights are sorted by cheapest return flights first.

Deals found on 11/8

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, January is the cheapest month in which you can book a flight from Panama (average of R15 539). Flying from Panama in March will prove the most costly (average of R33 878). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Panama City Tocumen Intl, with prices starting at R1 779. Explore other affordable destinations below.

Panama City Tocumen Intl
Panama City Tocumen Intl
From R1 779

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Direct flights from Central America

Book a direct flight from one of these other cities located in Central America.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 14 August 2026.

  • What is the cheapest month to fly from Panama?

    January is currently the cheapest month to fly from Panama. At this moment in time March is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama?

    Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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