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R8 264+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — JNB
Oct 14 — Oct 211
1 adult
1 adult, Economy

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 14 September 2025.

Good round-trip deal

R17 589 or less

Good one-way deal

R1 337 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 14 September 2025.

Thu 22/19:30PTY - CPT
2 stops39h 10mUnited Airlines
Sun 8/220:50CPT - PTY
2 stops48h 05mUnited Airlines
Deal found 13/9R17 883
Mon 9/29:13PTY - CPT
1 stop23h 57mUnited Airlines
Mon 23/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 13/9R18 265
Fri 23/118:41PTY - CPT
2 stops53h 59mUnited Airlines
Sat 7/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 13/9R18 872
Tue 28/109:13PTY - JNB
2 stops41h 17mUnited Airlines
Sun 9/1119:45JNB - PTY
2 stops48h 46mUnited Airlines
Deal found 11/9R19 220
Sun 12/1019:55PTY - JNB
1 stop29h 55mAir France
Sun 19/1018:50JNB - PTY
1 stop29h 55mAir France
Deal found 12/9R21 077
Sun 12/109:30PTY - JNB
2 stops25h 15mUnited Airlines
Sun 19/1019:00JNB - PTY
2 stops32h 35mUnited Airlines
Deal found 12/9R24 289
Sun 8/28:16PTY - CPT
2 stops26h 44mUnited Airlines
Thu 12/220:50CPT - PTY
2 stops30h 45mUnited Airlines
Deal found 13/9R24 932
Sun 15/28:16PTY - JNB
2 stops27h 19mUnited Airlines
Thu 19/210:25JNB - PTY
2 stops34h 30mUnited Airlines
Deal found 11/9R25 019
Tue 28/1022:20PTY - JNB
1 stop30h 50mMultiple Airlines
Sun 9/1123:59JNB - PTY
2 stops42h 10mMultiple Airlines
Deal found 13/9R25 487
Sun 8/222:20PTY - CPT
2 stops40h 35mKLM
Thu 12/218:25CPT - PTY
2 stops29h 05mKLM
Deal found 11/9R28 126
Mon 9/222:05PTY - CPT
1 stop40h 50mMultiple Airlines
Mon 23/27:55CPT - PTY
1 stop43h 15mMultiple Airlines
Deal found 13/9R28 474
Sat 11/103:20PTY - JNB
3 stops28h 20mMultiple Airlines
Sun 19/1015:05JNB - PTY
2 stops32h 25mMultiple Airlines
Deal found 12/9R28 960

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 14 September 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

OR Tambo

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 22/1

9:30-7:40

2 stops39h 10m

Cape Town Intl

Sun 8/2

20:50-13:55

2 stops48h 05m

R17 883

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:13-16:10

1 stop23h 57m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R18 265

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 25/1

9:11-7:40

2 stops39h 29m

Cape Town Intl

Sat 7/2

18:45-6:13

2 stops42h 28m

R18 872

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 23/1

18:41-7:40

2 stops53h 59m

Cape Town Intl

Sat 7/2

18:45-6:13

2 stops42h 28m

R18 872

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/10

9:13-9:30

2 stops41h 17m

Johannesburg OR Tambo

Sun 9/11

19:45-13:31

2 stops48h 46m

R19 220

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 12/10

19:55-8:50

1 stop29h 55m

Johannesburg OR Tambo

Sun 19/10

18:50-17:45

1 stop29h 55m

R21 077

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 12/10

9:30-17:45

2 stops25h 15m

Johannesburg OR Tambo

Sun 19/10

19:00-20:35

2 stops32h 35m

R24 289

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 8/2

7:55-18:00

2 stops27h 05m

Cape Town Intl

Thu 12/2

20:50-20:35

2 stops30h 45m

R24 932

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 15/2

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Thu 19/2

10:25-13:55

2 stops34h 30m

R25 019

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/10

22:20-12:10

1 stop30h 50m

Johannesburg OR Tambo

Sun 9/11

23:59-11:09

2 stops42h 10m

R25 487

Flights are sorted by cheapest return flights first.

Deals found on 13/9

Showing 1-10 of 17 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, September is the cheapest month in which you can book a flight from Panama (average of R14 150). Flying from Panama in August will prove the most costly (average of R40 679). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama?

When flying from Panama check dates and pricing for the following: United Airlines. As it departs for the following popular destinations: Johannesburg.

United Airlines
United Airlines
From R1 014

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Bogotá El Dorado, with prices starting at R1 337. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From R77
Panama City Tocumen Intl
Panama City Tocumen Intl
From R110
Quito Mariscal Sucr
Quito Mariscal Sucr
From R160
Madrid Barajas
Madrid Barajas
From R1 013

Airline reviews for flights from Panama

Get insights into the airlines that provide service from Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama. In the last 7 days, Cheapflights users made a total of 594 507 searches.
Get a feel of what it's like to fly with United Airlines from Panama by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
8 931 reviews
Check prices

Entertainment

7,1

Boarding

7,7

Food

6,6

Comfort

7,3

Crew

8,1

Overall

7,4

Reviews

1 / 20
8,0
Excellent

FERNANDO,Sept 2024

YYC - IAH

Everything was good, maybe can give better foof flys more than 4 hours
United Airlines
7,4
Good
8 931 reviews
United Airlines
7,4
Good
8 931 reviews
Check prices

Entertainment

7,1

Boarding

7,7

Food

6,6

Comfort

7,3

Crew

8,1

Overall

7,4

Reviews

1 / 20
8,0
Excellent

FERNANDO,Sept 2024

YYC - IAH

Everything was good, maybe can give better foof flys more than 4 hours

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 14 September 2025.

  • What is the cheapest month to fly from Panama?

    September is currently the cheapest month to fly from Panama. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama?

    Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

See more FAQs

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama?

Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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