R4 115+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Jul 9 — Jul 161
1 adult
1 adult, Economy, 0 bags

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 9 June 2026. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 28/10

9:30-18:00

1 stop25h 30m

Cape Town Intl

Tue 10/11

20:50-20:02

2 stops54h 12m

R15 270

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 3/7

7:55-17:10

2 stops26h 15m

Cape Town Intl

Fri 10/7

20:00-14:14

2 stops49h 14m

R15 270

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/11

18:46-18:35

2 stops64h 49m

Johannesburg OR Tambo

Sun 15/11

22:00-13:31

2 stops46h 31m

R15 270

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 14/7

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Thu 23/7

19:00-4:04

2 stops40h 04m

R16 823

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 3/12

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Mon 7/12

19:45-20:34

2 stops31h 49m

R16 889

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 22/7

22:55-8:35

2 stops50h 40m

Johannesburg OR Tambo

Tue 28/7

19:00-4:04

2 stops40h 04m

R18 393

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 17/7

9:45-11:05

2 stops42h 20m

Johannesburg OR Tambo

Sun 26/7

19:00-4:04

2 stops40h 04m

R19 385
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 15/10

9:13-15:20

1 stop23h 07m

Cape Town Intl

Mon 19/10

19:50-19:31

1 stop30h 41m

R21 715

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 15/8

19:25-18:30

2 stops40h 05m

Johannesburg OR Tambo

Sat 22/8

19:00-20:41

2 stops32h 41m

R22 293

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 30/11

19:10-6:13

2 stops42h 03m

R22 557

Flights are sorted by cheapest return flights first.

Deals found on 7/6

Showing 1-10 of 19 resultsSorted by cheapest first
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Panama City Tocumen Intl, with prices starting at R1 816. Explore other affordable destinations below.

Panama City Tocumen Intl
Panama City Tocumen Intl
From R1 816

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Direct flights from Central America

Book a direct flight from one of these other cities located in Central America.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 9 June 2026.

  • How does Cheapflights help users find flights from Panama?

    Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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How does Cheapflights help users find flights from Panama?

Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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