R10 013+ Cheap flights from Panama

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CPT
Oct 8 — Oct 151
1 adult
1 adult, Economy

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 8 September 2025.

Good round-trip deal

R17 766 or less

Good one-way deal

R1 350 or less
Price to beat on a round-trip flight from Panama.
Price to beat on a one-way flight from Panama.

Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 8 September 2025.

Tue 11/1113:45PTY - JNB
2 stops36h 45mMultiple Airlines
Tue 25/1120:15JNB - PTY
2 stops30h 10mMultiple Airlines
Deal found 7/9R18 676
Mon 9/29:13PTY - CPT
1 stop23h 57mUnited Airlines
Mon 23/218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 8/9R19 360
Tue 28/109:30PTY - JNB
2 stops41h 00mUnited Airlines
Sun 9/1119:45JNB - PTY
2 stops41h 28mUnited Airlines
Deal found 7/9R19 395
Mon 1/1222:29PTY - CPT
2 stops36h 31mUnited Airlines
Sat 13/1218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 8/9R22 166
Fri 28/119:11PTY - CPT
2 stops39h 29mUnited Airlines
Sat 13/1218:45CPT - PTY
2 stops42h 28mUnited Airlines
Deal found 8/9R22 762
Mon 1/1218:45PTY - CPT
2 stops28h 05mAir France
Sat 13/127:55CPT - PTY
1 stop43h 15mAir France
Deal found 8/9R24 674
Sun 8/27:55PTY - CPT
2 stops27h 05mUnited Airlines
Thu 12/220:50CPT - PTY
2 stops30h 45mUnited Airlines
Deal found 6/9R25 182
Tue 11/1118:45PTY - JNB
1 stop44h 20mKLM
Tue 25/1123:59JNB - PTY
1 stop23h 31mKLM
Deal found 7/9R25 217
Sun 15/29:30PTY - JNB
2 stops26h 05mUnited Airlines
Thu 19/210:25JNB - PTY
2 stops34h 30mUnited Airlines
Deal found 7/9R25 270
Sun 8/222:20PTY - CPT
2 stops40h 35mKLM
Thu 12/218:25CPT - PTY
2 stops29h 05mKLM
Deal found 7/9R25 358
Sat 29/1118:45PTY - CPT
2 stops28h 05mAir France
Sun 14/127:55CPT - PTY
1 stop43h 15mAir France
Deal found 8/9R25 568
Fri 28/1110:00PTY - CPT
2 stops42h 00mUnited Airlines
Sun 14/1220:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 8/9R27 409

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 8 September 2025. In the last 7 days, Cheapflights users made a total of 594 507 searches

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 11/11

13:45-9:30

2 stops36h 45m

Johannesburg OR Tambo

Tue 25/11

20:15-19:25

2 stops30h 10m

R18 676

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:13-16:10

1 stop23h 57m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R19 360

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/10

9:30-9:30

2 stops41h 00m

Johannesburg OR Tambo

Sun 9/11

19:45-13:31

2 stops48h 46m

R19 395

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 1/12

22:29-18:00

2 stops36h 31m

Cape Town Intl

Sat 13/12

18:45-6:13

2 stops42h 28m

R22 166

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 1/12

22:29-18:00

2 stops36h 31m

Cape Town Intl

Sun 14/12

18:45-6:13

2 stops42h 28m

R22 166

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 28/11

9:11-7:40

2 stops39h 29m

Cape Town Intl

Sat 13/12

18:45-6:13

2 stops42h 28m

R22 762

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 30/11

9:11-7:40

2 stops39h 29m

Cape Town Intl

Sat 13/12

18:45-6:13

2 stops42h 28m

R22 762

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 30/11

9:11-7:40

2 stops39h 29m

Cape Town Intl

Sun 14/12

18:45-6:13

2 stops42h 28m

R22 762

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 2/12

22:29-7:40

2 stops50h 11m

Cape Town Intl

Sun 14/12

18:45-6:13

2 stops42h 28m

R22 762

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 2/12

22:29-7:40

2 stops50h 11m

Cape Town Intl

Sat 13/12

18:45-6:13

2 stops42h 28m

R22 762

Flights are sorted by cheapest return flights first.

Deals found on 7/9

Showing 1-10 of 21 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

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Direct flights from Central America

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Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 8 September 2025.
  • How does Cheapflights help users find flights from Panama?

    Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

  • Can Cheapflights find flights from Panama with no change fees?

    Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

Cheapflights helps you search for flights from Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.

Can Cheapflights find flights from Panama with no change fees?

Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!

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