R10 013+ Cheap flights from Panama
This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
What to know about flights from Panama
Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 8 September 2025.
Good round-trip deal | R17 766 or less |
|---|---|
Good one-way deal | R1 350 or less |
Find flights from Panama
Cheapest flights from PanamaExplore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 8 September 2025.
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 8 September 2025.
Find flights from Panama within your budget
Fly to
Route
Depart
Return
Price
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Tue 11/11
13:45-9:30
2 stops36h 45m
Johannesburg OR Tambo
Tue 25/11
20:15-19:25
2 stops30h 10m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Mon 9/2
9:13-16:10
1 stop23h 57m
Cape Town Intl
Mon 23/2
18:45-6:13
2 stops42h 28m
Panama CityJohannesburg
PTY - JNB
PTYJNB
Panama City Tocumen Intl
Tue 28/10
9:30-9:30
2 stops41h 00m
Johannesburg OR Tambo
Sun 9/11
19:45-13:31
2 stops48h 46m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Mon 1/12
22:29-18:00
2 stops36h 31m
Cape Town Intl
Sat 13/12
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Mon 1/12
22:29-18:00
2 stops36h 31m
Cape Town Intl
Sun 14/12
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Fri 28/11
9:11-7:40
2 stops39h 29m
Cape Town Intl
Sat 13/12
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Sun 30/11
9:11-7:40
2 stops39h 29m
Cape Town Intl
Sat 13/12
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Sun 30/11
9:11-7:40
2 stops39h 29m
Cape Town Intl
Sun 14/12
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Tue 2/12
22:29-7:40
2 stops50h 11m
Cape Town Intl
Sun 14/12
18:45-6:13
2 stops42h 28m
Panama CityCape Town
PTY - CPT
PTYCPT
Panama City Tocumen Intl
Tue 2/12
22:29-7:40
2 stops50h 11m
Cape Town Intl
Sat 13/12
18:45-6:13
2 stops42h 28m
Best time to book a flight from Panama
Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Travel insights for flights from Panama
Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.
What is the cheapest place to fly to from Panama?
The cheapest city to fly to from Panama is Bogotá El Dorado, with prices starting at R1 350. Explore other affordable destinations below.
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Direct flights from Central America
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Related info for your journey
Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 8 September 2025.
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It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama.
Can Cheapflights find flights from Panama with no change fees?
Yes, we can. To see specific flights from Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.
Can Cheapflights notify me if prices for flights from Panama become cheaper?
Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama today and book when you’re ready!