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Cheap flights from Panama City to Cape Town from R14 941

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CPT
Oct 16 — Oct 231
1 adult
1 adult, Economy

Cheap flight deals from Panama City to Cape Town

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cape Town (CPT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 16 September 2025.

Round-trip from

R17 266

One-way from

R14 941

Popular in

October

Cheapest in

May
United Airlines
  • United Airlines
  • 6/2-15/2
  • 4 total stops
  • 75h 32m total
  • Panama City to Cape Town
Search Deals
21/10
  • 21/10
  • 2 total stops
  • 48h 35m total
  • Panama City to Cape Town
Search Deals
Highest demand for flights based on searches. 24% potential increase in price (R156 863 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (R17 443 potential savings vs. average return price).
Search Deals

Find flight deals from Panama City to Cape Town

Cheapest flights from Panama City to Cape Town
Explore the most affordable flight options available from Panama City to Cape Town. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 September 2025.

Mon 13/1018:50PTY - CPT
1 stop43h 35mMultiple Airlines
Wed 5/1123:45CPT - PTY
2 stops27h 25mMultiple Airlines
Deal found 15/9R23 062
Wed 15/1018:50PTY - CPT
2 stops43h 40mMultiple Airlines
Wed 22/1014:00CPT - PTY
2 stops34h 45mMultiple Airlines
Deal found 15/9R23 443
Tue 16/915:30PTY - CPT
2 stops42h 40mUnited Airlines
Tue 23/920:00CPT - PTY
2 stops29h 37mUnited Airlines
Deal found 15/9R24 693
Wed 15/1018:50PTY - CPT
2 stops43h 40mKLM
Wed 22/1023:15CPT - PTY
1 stop24h 35mKLM
Deal found 15/9R25 109
Mon 29/129:11PTY - CPT
2 stops39h 29mUnited Airlines
Sat 10/118:45CPT - PTY
2 stops49h 37mUnited Airlines
Deal found 15/9R29 517
Mon 13/109:13PTY - CPT
1 stop23h 07mUnited Airlines
Wed 5/119:30CPT - PTY
2 stops62h 38mUnited Airlines
Deal found 15/9R29 812
Tue 16/922:05PTY - CPT
3 stops32h 55mMultiple Airlines
Tue 23/97:00CPT - PTY
3 stops34h 10mMultiple Airlines
Deal found 15/9R29 916

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Cape Town that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 16 September 2025.
Use the filters below to find and compare flights from Panama City to Cape Town that are best for you.

Fly from

Panama City

Fly to

Cape Town

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 6/2

8:55-16:10

2 stops48h 15m

Cape Town Intl

Sun 15/2

20:50-13:31

1 stop23h 41m

R17 266

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 22/1

9:30-7:40

2 stops39h 10m

Cape Town Intl

Sun 8/2

20:50-13:55

2 stops48h 05m

R17 873

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 25/1

9:11-7:40

2 stops39h 29m

Cape Town Intl

Sat 7/2

18:45-6:13

2 stops42h 28m

R18 862

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 23/1

18:41-7:40

2 stops53h 59m

Cape Town Intl

Sat 7/2

18:45-6:13

2 stops42h 28m

R18 862

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:13-16:10

1 stop23h 57m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R19 157

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 13/10

18:50-21:25

1 stop43h 35m

Cape Town Intl

Wed 5/11

23:45-20:10

2 stops27h 25m

R23 062

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 15/10

18:50-21:30

2 stops43h 40m

Cape Town Intl

Wed 22/10

14:00-17:45

2 stops34h 45m

R23 443

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 21/10

9:45-17:20

2 stops48h 35m

R14 941

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 21/10

20:00-11:50

1 stop32h 50m

R21 465

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 11/2

18:45-18:40

3 stops40h 55m

R50 201

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 15 results
1
2

Best time to book a flight from Panama City to Cape Town

Have a flexible travel schedule? Discover the best time to fly to Cape Town from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cape Town. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Cape Town?

    Airlines like United Airlines fly from Panama City to Cape Town in about 48h 15m. The time it takes to get you to your destination can typically vary by up to . The distance between Panama City and Cape Town is about 11294 km.

  • Can I find deals for flights from Panama City to Cape Town that include hotel bookings?

    Yes. In addition to deals on Panama City to Cape Town flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cape Town?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cape Town.

  • Can I find deals for business class flights from Panama City to Cape Town?

    Yes. Cheapflights offers flight deals from Panama City to Cape Town by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cape Town?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Cape Town (average of R110). Flying from Panama City to Cape Town in December is currently the most expensive (average of R187). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Cape Town?

Book flights to Cape Town if you plan to visit one of these locations
Stellenbosch
Hermanus
Paarl
Somerset West
Gordon's Bay
Franschhoek
Simon's Town
Wellington
Porterville

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Cape Town

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to OR Tambo flights

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How does Cheapflights help users find flights from Panama City to Cape Town?

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Why should you use Cheapflights to find cheap flight tickets from Panama City to Cape Town?

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Can Cheapflights find flights from Panama City to Cape Town with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City to Cape Town flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City to Cape Town become cheaper?

Of course! You can now track prices for flights from Panama City to Cape Town and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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