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Cheap flights from Panama City to Cape Town from R12 373

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CPT
May 10 — May 171
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Cape Town

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Cape Town
Explore the most affordable flight options available from Panama City to Cape Town. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 April 2026.

Sat 28/1112:04
PTY
-
CPT
2 stops36h 36m
United Airlines
Thu 10/1218:45
CPT
-
PTY
2 stops42h 28m
United Airlines
Deal found 7/4R17 870
Sat 28/119:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Mon 7/1218:45
CPT
-
PTY
2 stops32h 50m
United Airlines
Deal found 8/4R18 165
Fri 27/1118:31
PTY
-
CPT
2 stops33h 29m
Lufthansa
Mon 7/1218:45
CPT
-
PTY
2 stops42h 53m
Lufthansa
Deal found 8/4R19 806
Sun 29/119:11
PTY
-
CPT
2 stops25h 49m
United Airlines
Mon 7/1218:45
CPT
-
PTY
2 stops32h 50m
United Airlines
Deal found 8/4R20 807
Wed 25/1122:29
PTY
-
CPT
1 stop34h 41m
United Airlines
Mon 30/1118:45
CPT
-
PTY
2 stops32h 49m
United Airlines
Deal found 9/4R21 693
Wed 25/119:45
PTY
-
CPT
3 stops38h 50m
Multiple Airlines
Mon 30/1118:45
CPT
-
PTY
2 stops37h 15m
Multiple Airlines
Deal found 9/4R25 582
Thu 12/118:16
PTY
-
CPT
2 stops24h 54m
United Airlines
Mon 16/1120:50
CPT
-
PTY
2 stops30h 37m
United Airlines
Deal found 9/4R25 828
Mon 4/515:30
PTY
-
CPT
2 stops59h 00m
United Airlines
Fri 15/518:00
CPT
-
PTY
2 stops53h 12m
United Airlines
Deal found 7/4R26 173
Tue 9/621:55
PTY
-
CPT
2 stops40h 30m
Multiple Airlines
Tue 23/623:15
CPT
-
PTY
1 stop24h 35m
Multiple Airlines
Deal found 9/4R29 028
Sat 28/1118:31
PTY
-
CPT
2 stops33h 29m
Multiple Airlines
Thu 10/126:30
CPT
-
PTY
3 stops41h 25m
Multiple Airlines
Deal found 7/4R29 750

Find flight deals from Panama City to Cape Town

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cape Town (CPT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 April 2026.

Round-trip from

R26 173

One-way from

R12 373
United Airlines
  • United Airlines
  • 4/5-15/5
  • 4 total stops
  • 112h 12m total
  • Panama City to Cape Town
Search Deals
United Airlines
  • United Airlines
  • 20/6
  • 2 total stops
  • 56h 24m total
  • Panama City to Cape Town
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Cape Town that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 10 April 2026.
Use the filters below to find and compare flights from Panama City to Cape Town that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 17/9

9:12-9:30

2 stops41h 18m

Cape Town Intl

Mon 21/9

19:50-18:37

2 stops29h 47m

R31 046

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 30/4

13:49-12:55

2 stops40h 06m

Cape Town Intl

Thu 28/5

19:30-12:14

2 stops47h 44m

R31 768

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 4/5

18:50-5:50

1 stop28h 00m

Cape Town Intl

Fri 15/5

23:15-19:45

2 stops27h 30m

R33 327
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 5/10

18:50-5:50

1 stop28h 00m

Cape Town Intl

Sun 11/10

0:15-19:45

1 stop26h 30m

R34 722

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 20/5

20:05-11:50

1 stop32h 45m

Cape Town Intl

Wed 27/5

16:35-18:30

2 stops32h 55m

R35 296

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 17/9

20:10-11:50

1 stop32h 40m

Cape Town Intl

Mon 21/9

16:35-18:25

2 stops32h 50m

R42 205

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 20/5

18:50-21:25

1 stop43h 35m

Cape Town Intl

Wed 27/5

23:15-16:50

1 stop24h 35m

R43 583
Cheapest one-way

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 20/6

18:06-9:30

2 stops56h 24m

R12 373

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 20/6

10:10-14:00

3 stops44h 50m

R14 309
Fastest single journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 1/6

4:25-14:00

3 stops26h 35m

R15 425

Flights are sorted by cheapest return flights first.

Deals found on 8/4

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama City to Cape Town

Have a flexible travel schedule? Discover the best time to fly to Cape Town from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cape Town. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Cape Town?

    Airlines like United Airlines and KLM fly from Panama City to Cape Town in about 28h. The time it takes to get you to your destination can typically vary by up to 13h 18m. The distance between Panama City and Cape Town is about 11294 km. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Cape Town that include hotel bookings?

    Yes. In addition to deals on Panama City to Cape Town flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cape Town?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cape Town.

  • Can I find deals for business class flights from Panama City to Cape Town?

    Yes. Cheapflights offers flight deals from Panama City to Cape Town by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Cape Town?

Book flights to Cape Town if you plan to visit one of these locations
Stellenbosch
Paarl
Gordon's Bay
Hermanus
Somerset West
Franschhoek
Simon's Town
Wellington
Porterville
Atlantis

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Cape Town

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to OR Tambo flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama City to Cape Town?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Cape Town from Panama City today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama City to Cape Town?

Cheapflights simply makes it quick and affordable to book flights from Panama City to Cape Town by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City to Cape Town with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City to Cape Town flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City to Cape Town become cheaper?

Of course! You can now track prices for flights from Panama City to Cape Town and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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