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Cheap flights from Cape Town to Panama from R18 881

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
CPT — PTY
Mar 1 — Mar 81
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cape Town to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Cape Town to Panama
Explore the most affordable flight options available from Cape Town to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 January 2026.

Thu 5/1120:50
CPT
-
PTY
2 stops29h 48m
United Airlines
Fri 13/1110:00
PTY
-
CPT
2 stops47h 10m
United Airlines
Deal found 29/1R18 881
Sun 15/39:00
CPT
-
PTY
2 stops38h 30m
KLM
Sun 22/318:45
PTY
-
CPT
1 stop44h 10m
KLM
Deal found 29/1R22 935
Sun 15/37:55
CPT
-
PTY
1 stop43h 15m
Multiple Airlines
Sun 22/318:45
PTY
-
CPT
1 stop44h 10m
Multiple Airlines
Deal found 29/1R22 999
Thu 5/117:00
CPT
-
PTY
3 stops32h 50m
Multiple Airlines
Fri 13/1118:31
PTY
-
CPT
2 stops33h 29m
Multiple Airlines
Deal found 29/1R25 329
Thu 21/519:50
CPT
-
PTY
2 stops28h 20m
United Airlines
Mon 25/59:13
PTY
-
CPT
1 stop23h 07m
United Airlines
Deal found 28/1R30 293
Thu 21/513:00
CPT
-
PTY
2 stops38h 00m
Qatar Airways
Mon 25/513:10
PTY
-
CPT
2 stops39h 20m
Qatar Airways
Deal found 28/1R36 103

Find flight deals from Cape Town to Panama

Keep the following information in mind while searching for Cape Town to Panama flight deals. Data was last updated 30 January 2026.

Round-trip from

R22 935

Popular in

September

Cheapest in

January

Average price

R16 806
KLM
  • KLM
  • 15/3-22/3
  • 3 total stops
  • 82h 40m total
  • Cape Town to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (R26 016 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R5 299 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Cape Town to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 30 January 2026.
Use the filters below to find and compare flights from Cape Town to Panama that are best for you.

Fly from

Cape Town

Fly to

Panama

Route

Depart

Return

Price

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 15/3

9:00-16:30

2 stops38h 30m

Panama City Tocumen Intl

Sun 22/3

18:45-21:55

1 stop44h 10m

R22 935

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 15/3

7:55-20:10

1 stop43h 15m

Panama City Tocumen Intl

Sun 22/3

18:45-21:55

1 stop44h 10m

R22 999

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 21/5

19:50-17:10

2 stops28h 20m

Panama City Tocumen Intl

Mon 25/5

9:13-15:20

1 stop23h 07m

R30 293

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 21/5

13:00-20:00

2 stops38h 00m

Panama City Tocumen Intl

Mon 25/5

13:10-11:30

2 stops39h 20m

R36 103

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 8/2

7:00-8:50

3 stops32h 50m

R37 188

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 8/2

0:30-11:34

3 stops42h 04m

R38 736

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 9/2

23:45-16:30

1 stop23h 45m

R69 476

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 8/2

8:00-16:30

1 stop39h 30m

R69 476

Flights are sorted by cheapest return flights first.

Deals found on 29/1

Best time to book a flight from Cape Town to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cape Town with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Town to Panama

What is the cheapest month to book a flight from Cape Town to Panama?

Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R13 215). Flying from Cape Town to Panama in December is currently the most expensive (average of R20 765). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 30 January 2026.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from Cape Town to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 444 reviews
Check prices

Crew

8,4

Overall

7,7

Food

7,3

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7,7
Good
1 444 reviews
KLM
7,7
Good
1 444 reviews
Check prices

Crew

8,4

Overall

7,7

Food

7,3

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Air France
7,4
Good
1 528 reviews
KLM
7,7
Good
1 444 reviews
Check prices

Crew

8,4

Overall

7,7

Food

7,3

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
United Airlines
7,4
Good
9 219 reviews
KLM
7,7
Good
1 444 reviews
Check prices

Crew

8,4

Overall

7,7

Food

7,3

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Cape Town to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cape Town to Panama?

    Most people fly from Cape Town Intl (CPT) if they book a flight from Cape Town to Panama. Cape Town Intl is conveniently located just 15,6 km from Cape Town’s city centre.

  • How long is the flight from Cape Town to Panama?

    Airlines like KLM and United Airlines fly from Cape Town to Panama in about 28h 20m. The time it takes to get you to your destination can typically vary by up to 10h 10m. Cape Town and Panama are separated by a distance of 11294 km. This flight may include one or multiple stops.

  • Can I find deals for flights from Cape Town to Panama that include hotel bookings?

    Yes. In addition to deals on Cape Town to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cape Town to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Town to Panama.

  • Can I find deals for business class flights from Cape Town to Panama?

    Yes. Cheapflights offers flight deals from Cape Town to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Town to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R13 215). Flying from Cape Town to Panama in December is currently the most expensive (average of R20 765). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cape Town to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to Guatemala City flights
Cape Town to San José flights
OR Tambo to Liberia flights

Top 3 airlines flying from Cape Town to Panama

Discover the top 3 airlines that operate flights from Cape Town to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 30 January 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 116AverageR20 751FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR21 514AverageR24 003FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 139AverageR23 840FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Cape Town to Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Cape Town to Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Cape Town to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Cape Town to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Cape Town to Panama with no change fees?

Yes, we can. To see specific flights from Cape Town to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Cape Town to Panama become cheaper?

Of course! You can now track prices for flights from Cape Town to Panama and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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