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Cheap flights from Cape Town to Panama from R23 517

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
CPT — PTY
Apr 11 — Apr 181
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cape Town to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Cape Town to Panama
Explore the most affordable flight options available from Cape Town to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 March 2026.

Thu 5/1120:50
CPT
-
PTY
2 stops29h 48m
United Airlines
Thu 19/1116:41
PTY
-
CPT
2 stops64h 29m
United Airlines
Deal found 10/3R23 517
Tue 21/423:15
CPT
-
PTY
1 stop24h 35m
KLM
Tue 28/418:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 7/3R25 219
Mon 16/318:30
CPT
-
PTY
2 stops44h 24m
Multiple Airlines
Sun 3/518:31
PTY
-
CPT
2 stops31h 59m
Multiple Airlines
Deal found 11/3R27 084
Thu 23/418:25
CPT
-
PTY
2 stops29h 25m
Multiple Airlines
Thu 30/417:55
PTY
-
CPT
3 stops68h 30m
Multiple Airlines
Deal found 9/3R27 690
Thu 30/413:00
CPT
-
PTY
2 stops38h 00m
Qatar Airways
Mon 4/513:49
PTY
-
CPT
2 stops38h 41m
Qatar Airways
Deal found 11/3R28 672
Thu 5/1117:15
CPT
-
PTY
1 stop33h 35m
Turkish Airlines
Thu 19/1118:45
PTY
-
CPT
1 stop34h 05m
Turkish Airlines
Deal found 10/3R29 817
Thu 15/1016:35
CPT
-
PTY
2 stops32h 50m
Turkish Airlines
Mon 19/1020:10
PTY
-
CPT
1 stop32h 40m
Turkish Airlines
Deal found 11/3R30 455

Find flight deals from Cape Town to Panama

Keep the following information in mind while searching for Cape Town to Panama flight deals. Data was last updated 12 March 2026.

Round-trip from

R25 219

Popular in

January

Cheapest in

April

Average price

R23 042
KLM
  • KLM
  • 21/4-28/4
  • 2 total stops
  • 68h 10m total
  • Cape Town to Panama
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R61 404 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R21 305 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Cape Town to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 12 March 2026.
Use the filters below to find and compare flights from Cape Town to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 21/4

23:45-16:50

2 stops48h 05m

Panama City Tocumen Intl

Tue 28/4

18:50-21:25

1 stop43h 35m

R26 282

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 23/4

18:25-16:50

2 stops29h 25m

Panama City Tocumen Intl

Thu 30/4

17:55-21:25

3 stops68h 30m

R27 690

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 30/4

13:00-20:00

2 stops38h 00m

Panama City Tocumen Intl

Sat 2/5

13:49-11:30

2 stops38h 41m

R30 750

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 12/4

20:00-14:14

2 stops49h 14m

Panama City Tocumen Intl

Fri 1/5

8:11-17:10

2 stops25h 59m

R33 025
Fastest return journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 30/4

19:50-16:12

2 stops27h 22m

Panama City Tocumen Intl

Mon 4/5

9:13-15:20

1 stop23h 07m

R33 156

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 1/5

20:00-18:37

2 stops29h 37m

Panama City Tocumen Intl

Tue 5/5

9:13-9:30

2 stops41h 17m

R33 810

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 12/4

23:45-19:45

1 stop27h 00m

Panama City Tocumen Intl

Fri 1/5

18:50-21:25

1 stop43h 35m

R34 236

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 12/4

15:20-16:50

2 stops32h 30m

Panama City Tocumen Intl

Fri 1/5

18:50-21:25

1 stop43h 35m

R34 416

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 21/4

15:20-18:40

3 stops34h 20m

Panama City Tocumen Intl

Tue 28/4

20:25-9:30

3 stops30h 05m

R34 596

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 1/5

16:35-18:30

2 stops32h 55m

Panama City Tocumen Intl

Wed 6/5

22:20-11:50

1 stop30h 30m

R35 529

Flights are sorted by cheapest return flights first.

Deals found on 7/3

Sorted by cheapest first

Best time to book a flight from Cape Town to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cape Town with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Town to Panama

What is the cheapest month to book a flight from Cape Town to Panama?

Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R13 550). Flying from Cape Town to Panama in January is currently the most expensive (average of R37 738). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 12 March 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from Cape Town to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 470 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Overall

7,8

Crew

8,4

Food

7,3

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 470 reviews
KLM
7,8
Good
1 470 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Overall

7,8

Crew

8,4

Food

7,3

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,4
Good
1 544 reviews
KLM
7,8
Good
1 470 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Overall

7,8

Crew

8,4

Food

7,3

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 418 reviews
KLM
7,8
Good
1 470 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Overall

7,8

Crew

8,4

Food

7,3

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Cape Town to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cape Town to Panama?

    Most people fly from Cape Town Intl (CPT) if they book a flight from Cape Town to Panama. Cape Town Intl is conveniently located just 15,6 km from Cape Town’s city centre.

  • How long is the flight from Cape Town to Panama?

    Airlines like KLM and Qatar Airways fly from Cape Town to Panama in about 38h. The time it takes to get you to your destination can typically vary by up to 10h 05m. Cape Town and Panama are separated by a distance of 11294 km. This flight may include one or multiple stops.

  • Can I find deals for flights from Cape Town to Panama that include hotel bookings?

    Yes. In addition to deals on Cape Town to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cape Town to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Town to Panama.

  • Can I find deals for business class flights from Cape Town to Panama?

    Yes. Cheapflights offers flight deals from Cape Town to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Town to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R13 550). Flying from Cape Town to Panama in January is currently the most expensive (average of R37 738). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cape Town to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to Guatemala City flights
Cape Town to San José flights
OR Tambo to Liberia flights

Top 3 airlines flying from Cape Town to Panama

Discover the top 3 airlines that operate flights from Cape Town to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 12 March 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 743AverageR21 039FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR22 674AverageR25 192FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 725AverageR24 445FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Cape Town to Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Cape Town to Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Cape Town to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Cape Town to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Cape Town to Panama with no change fees?

Yes, we can. To see specific flights from Cape Town to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Cape Town to Panama become cheaper?

Of course! You can now track prices for flights from Cape Town to Panama and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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