Find flights
When to book
Airlines
FAQs

Cheap flights from Cape Town to Panama from R12 553

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/5. Fares are subject to change and may not be available on all flights or dates of travel.
CPT — PTY
Apr 25 — May 21
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cape Town to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Cape Town to Panama
Explore the most affordable flight options available from Cape Town to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 March 2026.

Sun 10/523:15
CPT
-
PTY
1 stop24h 35m
KLM
Sat 23/518:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 26/3R26 865
Fri 8/514:00
CPT
-
PTY
2 stops36h 45m
Multiple Airlines
Fri 15/518:50
PTY
-
CPT
1 stop43h 35m
Multiple Airlines
Deal found 23/3R26 984
Sat 9/514:00
CPT
-
PTY
2 stops37h 00m
Multiple Airlines
Fri 22/518:50
PTY
-
CPT
1 stop43h 35m
Multiple Airlines
Deal found 26/3R27 051
Sun 10/518:25
CPT
-
PTY
2 stops29h 25m
KLM
Sun 24/518:50
PTY
-
CPT
2 stops55h 55m
KLM
Deal found 26/3R27 221
Sat 9/514:00
CPT
-
PTY
2 stops37h 00m
Multiple Airlines
Sun 24/518:50
PTY
-
CPT
2 stops55h 55m
Multiple Airlines
Deal found 26/3R27 237
Fri 1/523:45
CPT
-
PTY
2 stops48h 05m
Multiple Airlines
Fri 15/518:50
PTY
-
CPT
2 stops55h 55m
Multiple Airlines
Deal found 22/3R28 185
Sat 9/523:15
CPT
-
PTY
1 stop24h 35m
KLM
Sat 23/518:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 26/3R28 760
Fri 8/520:00
CPT
-
PTY
2 stops55h 27m
United Airlines
Tue 26/518:41
PTY
-
CPT
2 stops55h 49m
United Airlines
Deal found 26/3R29 031
Fri 1/523:15
CPT
-
PTY
1 stop24h 35m
KLM
Fri 15/518:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 22/3R29 944

Find flight deals from Cape Town to Panama

Keep the following information in mind while searching for Cape Town to Panama flight deals. Data was last updated 26 March 2026.

Round-trip from

R26 865

One-way from

R12 553

Popular in

January

Cheapest in

April

Average price

R23 820
KLM
  • KLM
  • 10/5-23/5
  • 2 total stops
  • 68h 10m total
  • Cape Town to Panama
Search Deals
26/5
  • 26/5
  • 3 total stops
  • 49h 10m total
  • Cape Town to Panama
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R65 627 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R22 768 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Cape Town to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 26 March 2026.
Use the filters below to find and compare flights from Cape Town to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 8/5

14:00-19:45

2 stops36h 45m

Panama City Tocumen Intl

Fri 15/5

18:50-21:25

1 stop43h 35m

R26 984

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 9/5

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Fri 22/5

18:50-21:25

1 stop43h 35m

R28 760

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 1/5

23:45-16:50

2 stops48h 05m

Panama City Tocumen Intl

Fri 15/5

18:50-21:25

1 stop43h 35m

R28 811

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 1/5

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Fri 15/5

18:50-21:25

1 stop43h 35m

R29 944

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 8/5

16:35-20:25

1 stop34h 50m

Panama City Tocumen Intl

Fri 15/5

20:05-11:50

1 stop32h 45m

R33 886

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 12/5

13:00-20:00

2 stops38h 00m

Panama City Tocumen Intl

Fri 22/5

21:30-11:30

2 stops55h 00m

R36 288

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 15/4

18:25-8:01

2 stops44h 36m

Panama City Tocumen Intl

Fri 24/4

20:57-16:40

2 stops60h 43m

R36 542

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 12/5

13:00-20:00

2 stops38h 00m

Panama City Tocumen Intl

Thu 21/5

13:14-11:30

2 stops39h 16m

R39 080

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 12/4

20:00-16:12

2 stops51h 12m

Panama City Tocumen Intl

Wed 22/4

22:29-15:20

1 stop33h 51m

R39 909
Fastest return journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 10/4

20:00-16:12

2 stops27h 12m

Panama City Tocumen Intl

Thu 23/4

9:13-15:20

1 stop23h 07m

R46 710

Flights are sorted by cheapest return flights first.

Deals found on 24/3

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Cape Town to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cape Town with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Town to Panama

What is the cheapest month to book a flight from Cape Town to Panama?

Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R14 008). Flying from Cape Town to Panama in January is currently the most expensive (average of R39 012). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 26 March 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from Cape Town to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 478 reviews
Check prices

Food

7,3

Comfort

7,6

Overall

7,8

Crew

8,4

Boarding

7,8

Entertainment

7,1

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 478 reviews
KLM
7,8
Good
1 478 reviews
Check prices

Food

7,3

Comfort

7,6

Overall

7,8

Crew

8,4

Boarding

7,8

Entertainment

7,1

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,4
Good
1 553 reviews
KLM
7,8
Good
1 478 reviews
Check prices

Food

7,3

Comfort

7,6

Overall

7,8

Crew

8,4

Boarding

7,8

Entertainment

7,1

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 492 reviews
KLM
7,8
Good
1 478 reviews
Check prices

Food

7,3

Comfort

7,6

Overall

7,8

Crew

8,4

Boarding

7,8

Entertainment

7,1

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Cape Town to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cape Town to Panama?

    Most people fly from Cape Town Intl (CPT) if they book a flight from Cape Town to Panama. Cape Town Intl is conveniently located just 15,6 km from Cape Town’s city centre.

  • How long is the flight from Cape Town to Panama?

    Airlines like KLM fly from Cape Town to Panama in about 24h 35m. The time it takes to get you to your destination can typically vary by up to . Cape Town and Panama are separated by a distance of 11294 km.

  • Can I find deals for flights from Cape Town to Panama that include hotel bookings?

    Yes. In addition to deals on Cape Town to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cape Town to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Town to Panama.

  • Can I find deals for business class flights from Cape Town to Panama?

    Yes. Cheapflights offers flight deals from Cape Town to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Town to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R14 008). Flying from Cape Town to Panama in January is currently the most expensive (average of R39 012). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cape Town to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Guatemala City flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to Liberia flights

Top 3 airlines flying from Cape Town to Panama

Discover the top 3 airlines that operate flights from Cape Town to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 26 March 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR19 376AverageR21 732FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR23 671AverageR26 446FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR24 526AverageR25 270FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Cape Town to Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Cape Town to Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Cape Town to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Cape Town to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Cape Town to Panama with no change fees?

Yes, we can. To see specific flights from Cape Town to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Cape Town to Panama become cheaper?

Of course! You can now track prices for flights from Cape Town to Panama and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.