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Cheap flights from Cape Town to Panama from R14 134

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
CPT — PTY
May 1 — May 81
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cape Town to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Cape Town to Panama
Explore the most affordable flight options available from Cape Town to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1 April 2026.

Fri 15/514:00
CPT
-
PTY
2 stops33h 50m
KLM
Fri 22/518:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 31/3R28 712
Fri 15/513:15
CPT
-
PTY
2 stops32h 15m
Multiple Airlines
Fri 22/57:35
PTY
-
CPT
2 stops30h 20m
Multiple Airlines
Deal found 31/3R29 889
Mon 11/523:15
CPT
-
PTY
1 stop24h 35m
KLM
Mon 18/518:50
PTY
-
CPT
2 stops55h 55m
KLM
Deal found 27/3R30 059
Mon 11/514:00
CPT
-
PTY
2 stops36h 45m
Air France
Mon 18/521:55
PTY
-
CPT
2 stops36h 25m
Air France
Deal found 27/3R31 202
Fri 20/1120:50
CPT
-
PTY
1 stop23h 41m
United Airlines
Tue 24/118:55
PTY
-
CPT
2 stops26h 05m
United Airlines
Deal found 27/3R32 651

Find flight deals from Cape Town to Panama

Keep the following information in mind while searching for Cape Town to Panama flight deals. Data was last updated 1 April 2026.

Round-trip from

R28 712

One-way from

R14 134

Popular in

January

Cheapest in

April

Average price

R19 284
KLM
  • KLM
  • 15/5-22/5
  • 3 total stops
  • 77h 25m total
  • Cape Town to Panama
Search Deals
11/5
  • 11/5
  • 3 total stops
  • 34h 35m total
  • Cape Town to Panama
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R66 662 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R23 123 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Cape Town to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 1 April 2026.
Use the filters below to find and compare flights from Cape Town to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 15/5

14:00-16:50

2 stops33h 50m

Panama City Tocumen Intl

Fri 22/5

18:50-21:25

1 stop43h 35m

R28 712

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 16/5

14:00-16:50

2 stops33h 50m

Panama City Tocumen Intl

Sat 23/5

18:50-21:25

1 stop43h 35m

R29 121

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 11/5

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Mon 18/5

18:50-9:45

2 stops55h 55m

R30 059

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 15/5

18:25-16:50

2 stops29h 25m

Panama City Tocumen Intl

Fri 22/5

17:55-5:50

3 stops52h 55m

R30 110
Fastest return journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 11/5

9:55-14:15

3 stops35h 20m

Panama City Tocumen Intl

Mon 18/5

4:25-17:20

3 stops29h 55m

R32 872

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 16/5

6:05-18:40

3 stops43h 35m

Panama City Tocumen Intl

Sat 23/5

4:25-20:25

3 stops33h 00m

R35 123
Cheapest one-way

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 11/5

15:05-18:40

3 stops34h 35m

R14 134
Fastest single journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 11/5

23:15-16:50

1 stop24h 35m

R20 426

Flights are sorted by cheapest return flights first.

Deals found on 27/3

Sorted by cheapest first

Best time to book a flight from Cape Town to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cape Town with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Town to Panama

What is the cheapest month to book a flight from Cape Town to Panama?

Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R14 117). Flying from Cape Town to Panama in January is currently the most expensive (average of R39 317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 1 April 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from Cape Town to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 481 reviews
Check prices

Boarding

7,8

Comfort

7,6

Overall

7,8

Food

7,3

Entertainment

7,1

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 481 reviews
KLM
7,8
Good
1 481 reviews
Check prices

Boarding

7,8

Comfort

7,6

Overall

7,8

Food

7,3

Entertainment

7,1

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,4
Good
1 559 reviews
KLM
7,8
Good
1 481 reviews
Check prices

Boarding

7,8

Comfort

7,6

Overall

7,8

Food

7,3

Entertainment

7,1

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 529 reviews
KLM
7,8
Good
1 481 reviews
Check prices

Boarding

7,8

Comfort

7,6

Overall

7,8

Food

7,3

Entertainment

7,1

Crew

8,4

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Cape Town to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cape Town to Panama?

    Most people fly from Cape Town Intl (CPT) if they book a flight from Cape Town to Panama. Cape Town Intl is conveniently located just 15,6 km from Cape Town’s city centre.

  • How long is the flight from Cape Town to Panama?

    Airlines like KLM fly from Cape Town to Panama in about 33h 50m. The time it takes to get you to your destination can typically vary by up to . Cape Town and Panama are separated by a distance of 11294 km.

  • Can I find deals for flights from Cape Town to Panama that include hotel bookings?

    Yes. In addition to deals on Cape Town to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cape Town to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Town to Panama.

  • Can I find deals for business class flights from Cape Town to Panama?

    Yes. Cheapflights offers flight deals from Cape Town to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Town to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R14 117). Flying from Cape Town to Panama in January is currently the most expensive (average of R39 317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cape Town to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Guatemala City flights
OR Tambo to Liberia flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to San José flights

Top 3 airlines flying from Cape Town to Panama

Discover the top 3 airlines that operate flights from Cape Town to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 1 April 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR19 527AverageR21 902FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR23 856AverageR26 653FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR24 718AverageR25 468FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Cape Town to Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Cape Town to Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Cape Town to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Cape Town to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Cape Town to Panama with no change fees?

Yes, we can. To see specific flights from Cape Town to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Cape Town to Panama become cheaper?

Of course! You can now track prices for flights from Cape Town to Panama and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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