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Cheap flights from Cape Town to Panama from R14 250

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/1. Fares are subject to change and may not be available on all flights or dates of travel.
CPT — PTY
Dec 15 — Dec 221
1 adult
1 adult, Economy, 0 bags

Find flight deals from Cape Town to Panama

Enter your travel dates to find the best prices.

Cheapest flights from Cape Town to Panama
Explore the most affordable flight options available from Cape Town to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 November 2025.

Wed 10/127:55CPT - PTY
1 stop43h 15mAir France
Sun 28/1218:40PTY - CPT
2 stops28h 10mAir France
Deal found 13/11R32 516
Wed 10/127:55CPT - PTY
2 stops39h 35mMultiple Airlines
Sun 28/1218:40PTY - CPT
2 stops28h 10mMultiple Airlines
Deal found 13/11R32 892

Cheap flight deals from Cape Town to Panama

Keep the following information in mind while searching for Cape Town to Panama flight deals. Data was last updated 15 November 2025.

Round-trip from

R25 545

One-way from

R14 250

Popular in

September

Cheapest in

January

Average price

R24 537
KLM
  • KLM
  • 11/3-15/3
  • 3 total stops
  • 57h 30m total
  • Cape Town to Panama
Search Deals
28/1
  • 28/1
  • 3 total stops
  • 54h 21m total
  • Cape Town to Panama
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (R25 886 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R5 708 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Cape Town to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 15 November 2025.
Use the filters below to find and compare flights from Cape Town to Panama that are best for you.

Fly from

Cape Town

Fly to

Panama

Route

Depart

Return

Price

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 11/3

18:25-16:30

2 stops29h 05m

Panama City Tocumen Intl

Sun 15/3

18:45-6:10

1 stop28h 25m

R25 545

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 11/3

7:55-16:30

2 stops39h 35m

Panama City Tocumen Intl

Sun 15/3

22:20-17:20

2 stops36h 00m

R25 869

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 10/12

7:55-20:10

1 stop43h 15m

Panama City Tocumen Intl

Sun 28/12

18:40-5:50

2 stops28h 10m

R32 516

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 10/12

7:55-16:30

2 stops39h 35m

Panama City Tocumen Intl

Sun 28/12

18:40-5:50

2 stops28h 10m

R32 892

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 28/1

8:45-8:06

3 stops54h 21m

R14 250

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 29/1

15:30-8:50

3 stops48h 20m

R15 036

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 30/1

18:55-20:34

3 stops56h 39m

R15 925

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 30/1

23:45-19:55

1 stop27h 10m

R18 983

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 28/1

19:50-16:45

1 stop27h 55m

R23 733

Flights are sorted by cheapest return flights first.

Deals found on 12/11

Best time to book a flight from Cape Town to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cape Town with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Town to Panama

What is the cheapest month to book a flight from Cape Town to Panama?

Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R14 148). Flying from Cape Town to Panama in December is currently the most expensive (average of R24 126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CPT to PA?

Find hourly flight availability from Cape Town to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 November 2025.

Unlike at midday, when flights are generally more expensive, you can save up to 29% on flights from Cape Town to Panama by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 15 November 2025.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from Cape Town to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 411 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Crew

8,4

Food

7,3

Overall

7,7

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7,7
Good
1 411 reviews
KLM
7,7
Good
1 411 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Crew

8,4

Food

7,3

Overall

7,7

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7,4
Good
1 487 reviews
KLM
7,7
Good
1 411 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Crew

8,4

Food

7,3

Overall

7,7

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7,4
Good
9 017 reviews
KLM
7,7
Good
1 411 reviews
Check prices

Boarding

7,8

Entertainment

7,1

Crew

8,4

Food

7,3

Overall

7,7

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Cape Town to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cape Town to Panama?

    Most people fly from Cape Town Intl (CPT) if they book a flight from Cape Town to Panama. Cape Town Intl is conveniently located just 15,6 km from Cape Town’s city centre.

  • How long is the flight from Cape Town to Panama?

    Airlines like KLM and Air France fly from Cape Town to Panama in about 29h 05m. The time it takes to get you to your destination can typically vary by up to 10h 30m. Cape Town and Panama are separated by a distance of 11294 km. This flight may include one or multiple stops.

  • Can I find deals for flights from Cape Town to Panama that include hotel bookings?

    Yes. In addition to deals on Cape Town to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cape Town to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Town to Panama.

  • Can I find deals for business class flights from Cape Town to Panama?

    Yes. Cheapflights offers flight deals from Cape Town to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Town to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cape Town to Panama (average of R14 148). Flying from Cape Town to Panama in December is currently the most expensive (average of R24 126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Cape Town to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
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Cape Town to Panama City flights
OR Tambo to Liberia flights
Cape Town to San José flights
OR Tambo to San José flights

Top 3 airlines flying from Cape Town to Panama

Discover the top 3 airlines that operate flights from Cape Town to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 15 November 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR17 988AverageR21 957FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR23 032AverageR25 966FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 782AverageR25 522FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Cape Town to Panama?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Cape Town to Panama. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Cape Town to Panama?

Millions of users choose and trust Cheapflights to book the best flight deals from Cape Town to Panama for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Cape Town to Panama with no change fees?

Yes, we can. To see specific flights from Cape Town to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Cape Town to Panama become cheaper?

Of course! You can now track prices for flights from Cape Town to Panama and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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