When flying from Sicily to South Africa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
These are just IATA (International Air Transport Association) codes. They are used in aviation to identify and differentiate airports. That’s why a Catania Fontanarossa Airport to Johannesburg OR Tambo Airport flight would often be abbreviated as a CTA to JNB flight. Ready for more IATA code knowledge? These are related airports for your current travel destination: Cape Town Intl Airport (CPT), Durban King Shaka Intl Airport (DUR), Port Elizabeth Airport (PLZ), George Airport (GRJ), East London Airport (ELS).
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