Cheap flights from South Africa to Panama from R10 427

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Jan 24 — Jan 311
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 December 2025.

Sun 28/1222:00JNB - PTY
2 stops29h 27mUnited Airlines
Mon 5/18:55PTY - JNB
2 stops26h 40mUnited Airlines
Deal found 24/12R23 901
Mon 29/1219:45JNB - PTY
2 stops55h 50mUnited Airlines
Tue 6/116:41PTY - JNB
2 stops42h 54mUnited Airlines
Deal found 25/12R24 384
Sun 28/1222:00JNB - PTY
2 stops50h 08mUnited Airlines
Tue 6/122:29PTY - JNB
2 stops37h 06mUnited Airlines
Deal found 23/12R31 680
Mon 29/1223:59JNB - PTY
1 stop23h 31mKLM
Tue 6/118:45PTY - JNB
1 stop44h 20mKLM
Deal found 25/12R37 176
Sun 28/1223:59JNB - PTY
1 stop23h 31mKLM
Tue 6/118:45PTY - JNB
1 stop44h 20mKLM
Deal found 23/12R37 709
Mon 29/1219:20JNB - PTY
1 stop31h 50mMultiple Airlines
Tue 6/118:45PTY - JNB
1 stop44h 20mMultiple Airlines
Deal found 24/12R38 309

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 25 December 2025.

Round-trip from

R19 421

One-way from

R10 427

Popular in

December

Cheapest in

January

Average price

R28 332
United Airlines
  • United Airlines
  • 23/1-30/1
  • 3 total stops
  • 65h 46m total
  • South Africa to Panama
5/2
  • 5/2
  • 3 total stops
  • 39h 00m total
  • South Africa to Panama
Highest demand for flights based on searches. 1% potential increase in price (R7 270 potential increase over avg. return price).
Cheapest flight prices on average. 1% potential price decrease (R6 455 potential savings vs. average return price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 25 December 2025.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 23/1

20:50-19:38

2 stops29h 48m

Panama City Tocumen Intl

Fri 30/1

8:55-18:00

2 stops26h 05m

R19 421

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 6/2

20:50-20:35

1 stop30h 45m

Panama City Tocumen Intl

Fri 13/2

11:35-16:10

2 stops45h 35m

R19 454

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 13/2

22:00-20:35

2 stops29h 35m

Panama City Tocumen Intl

Fri 27/2

7:55-18:35

2 stops27h 40m

R21 853

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 20/1

19:45-20:27

2 stops55h 42m

Panama City Tocumen Intl

Wed 24/6

22:29-17:25

2 stops59h 56m

R24 235

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 20/1

23:59-19:55

1 stop26h 56m

Panama City Tocumen Intl

Wed 24/6

18:50-21:35

1 stop43h 45m

R26 050

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 13/2

19:20-16:30

2 stops28h 10m

Panama City Tocumen Intl

Fri 27/2

18:45-22:05

1 stop44h 20m

R26 417

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 18/3

23:59-16:30

1 stop23h 31m

Panama City Tocumen Intl

Sun 29/3

21:55-21:20

2 stops40h 25m

R26 450

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 6/2

8:00-16:30

1 stop39h 30m

Panama City Tocumen Intl

Fri 13/2

22:20-5:50

1 stop24h 30m

R27 616

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 5/2

20:50-17:08

2 stops27h 18m

Panama City Tocumen Intl

Mon 9/2

22:29-18:00

2 stops36h 31m

R31 247

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 21/5

19:50-20:41

2 stops31h 51m

Panama City Tocumen Intl

Mon 25/5

9:13-15:20

1 stop23h 07m

R31 280

Flights are sorted by cheapest return flights first.

Deals found on 23/12

Showing 1-10 of 13 results
1
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 878). Flying from South Africa to Panama in September is currently the most expensive (average of R21 053). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ZA to PA?

Find hourly flight availability from South Africa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 25 December 2025.

Unlike at midday, when flights are generally more expensive, you can save up to 21% on flights from South Africa to Panama by exploring options for tickets in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 25 December 2025.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7,1

Comfort

7,6

Crew

8,3

Food

7,2

Boarding

7,7

Overall

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Entertainment

7,1

Comfort

7,6

Crew

8,3

Food

7,2

Boarding

7,7

Overall

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Entertainment

7,1

Comfort

7,6

Crew

8,3

Food

7,2

Boarding

7,7

Overall

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Entertainment

7,1

Comfort

7,6

Crew

8,3

Food

7,2

Boarding

7,7

Overall

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Entertainment

7,1

Comfort

7,6

Crew

8,3

Food

7,2

Boarding

7,7

Overall

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Africa to Panama?

    For as low as R26 050, United Airlines can have you in Panama from South Africa in 26h 56m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 878). Flying from South Africa to Panama in September is currently the most expensive (average of R21 053). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 25 December 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR17 534AverageR21 457FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR18 517AverageR21 814FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapestR22 451AverageR25 517FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 183AverageR25 458FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

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How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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