Find flights
When to book
Airlines
FAQs

Cheap flights from South Africa to Panama from R18 330

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Mar 9 — Mar 161
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 7 February 2026.

Sat 6/619:25
JNB
-
PTY
2 stops31h 35m
British Airways
Sun 21/621:05
PTY
-
JNB
2 stops29h 20m
British Airways
Deal found 6/2R18 330
Fri 5/619:25
JNB
-
PTY
2 stops55h 35m
British Airways
Sun 21/621:05
PTY
-
JNB
2 stops29h 20m
British Airways
Deal found 6/2R18 523
Thu 4/619:25
JNB
-
PTY
2 stops31h 35m
British Airways
Sun 21/621:05
PTY
-
JNB
2 stops29h 20m
British Airways
Deal found 6/2R18 668
Thu 12/222:00
JNB
-
PTY
2 stops29h 35m
United Airlines
Thu 19/28:16
PTY
-
JNB
2 stops27h 19m
United Airlines
Deal found 5/2R18 862
Mon 8/619:25
JNB
-
PTY
2 stops55h 35m
British Airways
Sun 21/621:05
PTY
-
JNB
2 stops29h 20m
British Airways
Deal found 6/2R19 153
Fri 5/610:25
JNB
-
PTY
2 stops50h 48m
United Airlines
Sat 20/67:55
PTY
-
JNB
2 stops27h 35m
United Airlines
Deal found 6/2R20 363
Fri 20/222:00
JNB
-
PTY
2 stops29h 35m
United Airlines
Sun 29/38:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Deal found 6/2R20 831
Sun 15/222:00
JNB
-
PTY
2 stops28h 38m
United Airlines
Mon 23/29:11
PTY
-
JNB
2 stops26h 24m
United Airlines
Deal found 5/2R21 040
Mon 8/622:00
JNB
-
PTY
2 stops29h 27m
United Airlines
Sat 20/67:55
PTY
-
JNB
2 stops27h 35m
United Airlines
Deal found 6/2R21 250
Sun 7/615:05
JNB
-
PTY
2 stops29h 26m
United Airlines
Sat 20/67:55
PTY
-
JNB
2 stops27h 35m
United Airlines
Deal found 6/2R21 363
Fri 5/615:05
JNB
-
PTY
2 stops46h 08m
United Airlines
Fri 19/612:04
PTY
-
JNB
2 stops47h 26m
United Airlines
Deal found 6/2R21 444
Sat 6/619:25
JNB
-
PTY
2 stops31h 35m
British Airways
Mon 22/613:10
PTY
-
JNB
2 stops58h 50m
British Airways
Deal found 6/2R21 718

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 7 February 2026.

Round-trip from

R18 330

Popular in

December

Cheapest in

January

Average price

R21 169
British Airways
  • British Airways
  • 6/6-21/6
  • 4 total stops
  • 60h 55m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (R4 436 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R4 777 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 7 February 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 6/6

19:25-20:00

2 stops31h 35m

Panama City Tocumen Intl

Sun 21/6

21:05-9:25

2 stops29h 20m

R18 330

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 5/6

19:25-20:00

2 stops55h 35m

Panama City Tocumen Intl

Sun 21/6

21:05-9:25

2 stops29h 20m

R18 523

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 4/6

19:25-20:00

2 stops31h 35m

Panama City Tocumen Intl

Sun 21/6

21:05-9:25

2 stops29h 20m

R18 668

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 5/6

10:25-6:13

2 stops50h 48m

Panama City Tocumen Intl

Sat 20/6

7:55-18:30

2 stops27h 35m

R20 363

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 20/2

22:00-20:35

2 stops29h 35m

Panama City Tocumen Intl

Sun 29/3

8:11-18:30

2 stops27h 19m

R20 831

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 7/6

15:05-13:31

2 stops29h 26m

Panama City Tocumen Intl

Sat 20/6

7:55-18:30

2 stops27h 35m

R21 363

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 5/6

15:05-6:13

2 stops46h 08m

Panama City Tocumen Intl

Fri 19/6

12:04-18:30

2 stops47h 26m

R21 444

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 6/6

19:25-20:00

2 stops31h 35m

Panama City Tocumen Intl

Mon 22/6

13:10-7:00

2 stops58h 50m

R21 718

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 6/6

19:25-20:00

2 stops31h 35m

Panama City Tocumen Intl

Sat 20/6

13:10-9:25

2 stops61h 15m

R21 718

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 5/6

15:05-6:13

2 stops46h 08m

Panama City Tocumen Intl

Tue 23/6

9:13-8:35

2 stops40h 22m

R21 799

Flights are sorted by cheapest return flights first.

Deals found on 6/2

Showing 1-10 of 16 results
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 664). Flying from South Africa to Panama in September is currently the most expensive (average of R20 395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 7 February 2026.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 450 reviews
Check prices

Food

7,3

Crew

8,4

Comfort

7,6

Entertainment

7,1

Boarding

7,8

Overall

7,7

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7,7
Good
1 450 reviews
KLM
7,7
Good
1 450 reviews
Check prices

Food

7,3

Crew

8,4

Comfort

7,6

Entertainment

7,1

Boarding

7,8

Overall

7,7

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Air France
7,4
Good
1 531 reviews
KLM
7,7
Good
1 450 reviews
Check prices

Food

7,3

Crew

8,4

Comfort

7,6

Entertainment

7,1

Boarding

7,8

Overall

7,7

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
United Airlines
7,4
Good
9 246 reviews
KLM
7,7
Good
1 450 reviews
Check prices

Food

7,3

Crew

8,4

Comfort

7,6

Entertainment

7,1

Boarding

7,8

Overall

7,7

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
British Airways
6,7
Okay
7 719 reviews
KLM
7,7
Good
1 450 reviews
Check prices

Food

7,3

Crew

8,4

Comfort

7,6

Entertainment

7,1

Boarding

7,8

Overall

7,7

Reviews

1 / 20
10,0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R23 445, British Airways can have you in Panama from South Africa in 29h 05m. Airlines will cover a distance of 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 664). Flying from South Africa to Panama in September is currently the most expensive (average of R20 395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Cape Town to San José flights
OR Tambo to Panama City flights
Cape Town to Panama City flights
OR Tambo to San José flights
Cape Town to Guatemala City flights
OR Tambo to Liberia flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 7 February 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR17 938AverageR20 876FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR18 479AverageR21 056FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR21 749AverageR25 065FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 392AverageR24 559FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.