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Cheap flights from South Africa to Panama from R10 803

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Jun 23 — Jun 301
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 May 2026.

Sat 20/610:25
JNB
-
PTY
2 stops48h 39m
United Airlines
Sun 28/615:30
PTY
-
JNB
2 stops44h 00m
United Airlines
Deal found 19/5R21 179
Sun 20/914:55
JNB
-
PTY
2 stops30h 20m
Multiple Airlines
Fri 25/917:55
PTY
-
JNB
2 stops35h 05m
Multiple Airlines
Deal found 21/5R23 501
Fri 19/615:00
JNB
-
PTY
2 stops40h 35m
Multiple Airlines
Fri 26/64:25
PTY
-
JNB
2 stops24h 30m
Multiple Airlines
Deal found 22/5R23 830
Sat 1/813:15
CPT
-
PTY
2 stops42h 20m
Multiple Airlines
Thu 3/913:24
PTY
-
CPT
2 stops37h 51m
Multiple Airlines
Deal found 23/5R26 860
Sat 1/819:50
CPT
-
PTY
1 stop39h 14m
United Airlines
Thu 3/917:51
PTY
-
CPT
2 stops62h 29m
United Airlines
Deal found 23/5R26 992
Sat 20/610:25
JNB
-
PTY
2 stops40h 06m
United Airlines
Sat 27/622:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Deal found 19/5R27 025
Sat 20/614:50
JNB
-
PTY
2 stops33h 10m
Multiple Airlines
Fri 26/617:55
PTY
-
JNB
2 stops35h 15m
Multiple Airlines
Deal found 19/5R29 578
Sat 20/614:50
JNB
-
PTY
2 stops33h 10m
Multiple Airlines
Sat 27/64:25
PTY
-
JNB
2 stops24h 45m
Multiple Airlines
Deal found 19/5R29 924
Tue 23/614:00
CPT
-
PTY
2 stops33h 50m
KLM
Tue 30/621:55
PTY
-
CPT
2 stops40h 30m
KLM
Deal found 23/5R31 044
Sun 20/918:50
JNB
-
PTY
1 stop31h 55m
Air France
Fri 25/921:55
PTY
-
JNB
1 stop29h 25m
Air France
Deal found 21/5R31 175
Sat 4/79:25
JNB
-
PTY
3 stops35h 50m
Multiple Airlines
Sat 11/74:25
PTY
-
JNB
3 stops22h 55m
Multiple Airlines
Deal found 20/5R31 455
Fri 5/623:15
CPT
-
PTY
1 stop24h 35m
KLM
Sat 5/921:41
PTY
-
CPT
2 stops40h 44m
KLM
Deal found 19/5R31 702

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 24 May 2026.

Round-trip from

R21 179

One-way from

R10 803

Popular in

December

Cheapest in

April

Average price

R21 245
United Airlines
  • United Airlines
  • 20/6-28/6
  • 4 total stops
  • 92h 39m total
  • South Africa to Panama
Search Deals
7/9
  • 7/9
  • 3 total stops
  • 25h 50m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (R6 898 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R6 936 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 24 May 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 20/6

10:25-4:04

2 stops48h 39m

Panama City Tocumen Intl

Sun 28/6

15:30-18:30

2 stops44h 00m

R21 179

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 20/9

14:55-14:15

2 stops30h 20m

Panama City Tocumen Intl

Fri 25/9

17:55-12:00

2 stops35h 05m

R23 501

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 19/6

15:00-0:35

2 stops40h 35m

Panama City Tocumen Intl

Fri 26/6

4:25-11:55

2 stops24h 30m

R23 830

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 1/8

19:50-4:04

1 stop39h 14m

Panama City Tocumen Intl

Thu 3/9

17:51-15:20

2 stops62h 29m

R26 992

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 20/6

10:25-19:31

2 stops40h 06m

Panama City Tocumen Intl

Sat 27/6

22:55-18:30

1 stop36h 35m

R27 025

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 20/6

14:50-17:00

2 stops33h 10m

Panama City Tocumen Intl

Fri 26/6

17:55-12:10

2 stops35h 15m

R29 578

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 4/7

9:25-14:15

3 stops35h 50m

Panama City Tocumen Intl

Sat 11/7

4:25-10:20

3 stops22h 55m

R31 455

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 18/11

13:45-21:05

2 stops62h 20m

Panama City Tocumen Intl

Sun 22/11

22:35-15:35

2 stops34h 00m

R31 669

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 5/6

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Sat 5/9

21:41-21:25

2 stops40h 44m

R31 702

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 23/6

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Tue 30/6

21:55-21:25

2 stops40h 30m

R32 443

Flights are sorted by cheapest return flights first.

Deals found on 21/5

Showing 1-10 of 28 resultsSorted by cheapest first
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 999). Flying from South Africa to Panama in September is currently the most expensive (average of R19 170). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 24 May 2026.
Check out reviews from past customers who have flown with KLM,Air France, andLATAM Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 521 reviews
Check prices

Food

7,3

Entertainment

7,2

Comfort

7,7

Boarding

7,8

Overall

7,8

Crew

8,4

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7,8
Good
1 521 reviews
KLM
7,8
Good
1 521 reviews
Check prices

Food

7,3

Entertainment

7,2

Comfort

7,7

Boarding

7,8

Overall

7,8

Crew

8,4

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air France
7,4
Good
1 591 reviews
KLM
7,8
Good
1 521 reviews
Check prices

Food

7,3

Entertainment

7,2

Comfort

7,7

Boarding

7,8

Overall

7,8

Crew

8,4

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
LATAM Airlines
7,4
Good
1 918 reviews
KLM
7,8
Good
1 521 reviews
Check prices

Food

7,3

Entertainment

7,2

Comfort

7,7

Boarding

7,8

Overall

7,8

Crew

8,4

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
United Airlines
7,4
Good
9 750 reviews
KLM
7,8
Good
1 521 reviews
Check prices

Food

7,3

Entertainment

7,2

Comfort

7,7

Boarding

7,8

Overall

7,8

Crew

8,4

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
British Airways
6,7
Okay
7 998 reviews
KLM
7,8
Good
1 521 reviews
Check prices

Food

7,3

Entertainment

7,2

Comfort

7,7

Boarding

7,8

Overall

7,8

Crew

8,4

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R31 702, United Airlines can have you in Panama from South Africa in 24h 35m. Airlines will cover a distance of 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 999). Flying from South Africa to Panama in September is currently the most expensive (average of R19 170). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Panama City flights
OR Tambo to San José flights
Cape Town to Guatemala City flights
Cape Town to San José flights
OR Tambo to Liberia flights

Top 5 airlines flying from South Africa to Panama

Discover the top 5 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 24 May 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapestR7 917AverageR14 643FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights
United AirlinesCheapestR18 861AverageR20 685FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR18 951AverageR22 307FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapestR23 875AverageR25 171FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR24 756AverageR26 515FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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