Cheap flights from South Africa to Panama from R12 277

JNB — PTY
Dec 3 — Dec 101
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama

Mon 2/1122:00 -
2 stops28h 38m
Mon 9/1122:29 -
2 stops61h 06m
Deal found 31/10R20 828
Thu 5/1122:00 -
1 stop29h 02m
Thu 12/1110:00 -
1 stop25h 35m
Deal found 2/11R20 928
Sun 15/1122:00 -
1 stop29h 02m
Mon 23/1112:04 -
3 stops71h 31m
Deal found 30/10R20 944
Wed 11/1115:05 -
2 stops35h 57m
Tue 26/119:28 -
2 stops40h 07m
Deal found 2/11R21 444
Tue 8/1219:45 -
2 stops31h 56m
Wed 30/1223:55 -
1 stop35h 40m
Deal found 2/11R22 475
Tue 17/1115:35 -
1 stop25h 16m
Mon 23/1112:02 -
1 stop17h 43m
Deal found 30/10R24 588
Thu 19/1117:15 -
1 stop33h 50m
Mon 23/1122:00 -
1 stop31h 05m
Deal found 31/10R26 750
Mon 16/1115:40 -
1 stop23h 29m
Fri 20/1112:02 -
1 stop17h 38m
Deal found 31/10R26 917
Sat 14/1120:50 -
1 stop30h 12m
Mon 28/1210:00 -
2 stops38h 40m
Deal found 30/10R27 100
Thu 19/1120:50 -
1 stop30h 12m
Mon 23/119:11 -
1 stop23h 59m
Deal found 1/11R32 889

Find flight deals from South Africa to Panama

Round-trip from

R19 630

One-way from

R12 277

Popular in

August

Cheapest in

April

Average price

R21 743
14/4-27/4
  • 14/4-27/4
  • 4 total stops
  • 50h 00m total
  • South Africa to Panama
27/1-31/12
  • 27/1-31/12
  • 3 total stops
  • 34h 25m total
  • South Africa to Panama
Highest demand for flights based on searches. 1% potential increase in price (R5 871 potential increase over avg. return price).
Cheapest flight prices on average. 1% potential price decrease (R6 490 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Wed 27/1

22:15-20:25

2 stops53h 10m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R16 203

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Mon 21/12

22:00-17:08

2 stops26h 08m

Panama City Tocumen Intl

Thu 14/1

16:41-18:35

2 stops42h 54m

R20 828

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Sat 23/1

20:50-19:38

2 stops29h 48m

Panama City Tocumen Intl

Sat 30/1

18:45-18:00

2 stops40h 15m

R20 828

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 10/11

10:10-6:46

2 stops51h 36m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R20 861

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Sun 15/11

22:00-20:02

1 stop29h 02m

Panama City Tocumen Intl

Mon 23/11

12:04-18:35

3 stops71h 31m

R20 944

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 19/1

19:35-17:05

2 stops28h 30m

Panama City Tocumen Intl

Fri 30/4

13:49-9:25

2 stops36h 36m

R22 059

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Wed 27/1

23:55-16:30

1 stop23h 35m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R22 358

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 8/12

19:45-20:41

2 stops31h 56m

Panama City Tocumen Intl

Wed 30/12

23:55-18:35

1 stop35h 40m

R22 475

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Mon 5/4

22:00-14:14

2 stops47h 14m

Panama City Tocumen Intl

Fri 30/4

9:45-18:30

1 stop25h 45m

R23 157

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Thu 28/1

18:50-17:10

2 stops29h 20m

Panama City Tocumen Intl

Mon 1/2

22:00-10:55

1 stop29h 55m

R24 920

Flights are sorted by cheapest return flights first.

Deals found on 31/10

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 789). Flying from South Africa to Panama in August is currently the most expensive (average of R26 850). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Check out reviews from past customers who have flown with United Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8,1

Food

6,7

Boarding

7,7

Comfort

7,3

Overall

7,3

Entertainment

7,1

Reviews

1 / 20
4,0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Crew

8,1

Food

6,7

Boarding

7,7

Comfort

7,3

Overall

7,3

Entertainment

7,1

Reviews

1 / 20
4,0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

  • How long is the flight from South Africa to Panama?

    For as low as R20 828, United Airlines can have you in Panama from South Africa in 26h 08m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 789). Flying from South Africa to Panama in August is currently the most expensive (average of R26 850). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Africa to Panama

Top airline flying from South Africa to Panama

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR19 279AverageR21 335FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

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