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Cheap flights from South Africa to Panama from R14 422

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Dec 5 — Dec 121
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 5 November 2025.

Round-trip from

R20 159

One-way from

R14 422

Popular in

December

Cheapest in

January

Average price

R25 879
United Airlines
  • United Airlines
  • 18/11-18/3
  • 4 total stops
  • 56h 50m total
  • South Africa to Panama
Search Deals
10/12
  • 10/12
  • 2 total stops
  • 33h 30m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 0% potential increase in price (R3 593 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R7 289 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 November 2025.

Tue 18/1120:50CPT - PTY
1 stop23h 41mUnited Airlines
Wed 18/315:41PTY - CPT
2 stops41h 29mUnited Airlines
Deal found 3/11R20 159
Tue 18/118:50CPT - PTY
3 stops39h 05mMultiple Airlines
Wed 18/314:55PTY - CPT
3 stops33h 35mMultiple Airlines
Deal found 3/11R26 856
Mon 15/1219:45JNB - PTY
2 stops55h 50mUnited Airlines
Tue 6/118:41PTY - JNB
2 stops55h 49mUnited Airlines
Deal found 3/11R30 309
Thu 18/1222:00JNB - PTY
2 stops26h 08mUnited Airlines
Thu 25/128:16PTY - JNB
2 stops27h 19mUnited Airlines
Deal found 3/11R34 721
Mon 15/1223:59JNB - PTY
2 stops27h 11mMultiple Airlines
Tue 6/122:20PTY - JNB
1 stop30h 50mMultiple Airlines
Deal found 2/11R44 190
Mon 15/1223:59JNB - PTY
2 stops27h 11mKLM
Tue 6/118:45PTY - JNB
1 stop44h 20mKLM
Deal found 3/11R45 376
Mon 15/1219:20JNB - PTY
1 stop31h 50mAir France
Tue 6/122:20PTY - JNB
1 stop30h 50mAir France
Deal found 2/11R45 882
Mon 10/1120:50CPT - PTY
2 stops48h 55mUnited Airlines
Mon 17/1119:20PTY - CPT
2 stops39h 40mUnited Airlines
Deal found 3/11R107 580
Sun 9/110:30CPT - PTY
2 stops37h 09mMultiple Airlines
Mon 17/1111:56PTY - CPT
1 stop35h 44mMultiple Airlines
Deal found 3/11R144 097

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 5 November 2025.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 18/11

20:50-13:31

1 stop23h 41m

Panama City Tocumen Intl

Wed 18/3

15:41-16:10

2 stops41h 29m

R20 159

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 10/2

0:30-0:40

3 stops31h 10m

Panama City Tocumen Intl

Tue 17/3

2:55-7:30

3 stops45h 35m

R21 624

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 11/2

20:50-19:38

2 stops29h 48m

Panama City Tocumen Intl

Wed 18/3

22:29-16:10

1 stop34h 41m

R22 514

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 18/3

19:35-14:20

2 stops49h 45m

Panama City Tocumen Intl

Sun 22/3

15:50-7:35

2 stops32h 45m

R24 153

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 11/3

18:25-16:30

2 stops29h 05m

Panama City Tocumen Intl

Sun 15/3

18:45-6:10

1 stop28h 25m

R26 036

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 11/3

7:55-16:30

2 stops39h 35m

Panama City Tocumen Intl

Sun 15/3

22:20-17:20

2 stops36h 00m

R26 193

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 18/11

8:50-16:55

3 stops39h 05m

Panama City Tocumen Intl

Wed 18/3

14:55-7:30

3 stops33h 35m

R26 856

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 11/2

23:59-16:30

1 stop23h 31m

Panama City Tocumen Intl

Sun 15/2

18:45-22:05

1 stop44h 20m

R28 042

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 18/3

23:59-16:30

1 stop23h 31m

Panama City Tocumen Intl

Sun 22/3

18:45-22:05

1 stop44h 20m

R28 129

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 18/3

19:20-16:30

2 stops28h 10m

Panama City Tocumen Intl

Sun 22/3

22:20-12:10

1 stop30h 50m

R28 460

Flights are sorted by cheapest return flights first.

Deals found on 4/11

Showing 1-10 of 25 results
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R8 249). Flying from South Africa to Panama in September is currently the most expensive (average of R22 043). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ZA to PA?

Find hourly flight availability from South Africa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 5 November 2025.

Unlike at midday, when flights are generally more expensive, you can save up to 23% on flights from South Africa to Panama by exploring options for tickets in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 5 November 2025.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 405 reviews
Check prices

Food

7,3

Entertainment

7,1

Boarding

7,8

Overall

7,7

Crew

8,4

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7,7
Good
1 405 reviews
KLM
7,7
Good
1 405 reviews
Check prices

Food

7,3

Entertainment

7,1

Boarding

7,8

Overall

7,7

Crew

8,4

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7,4
Good
1 482 reviews
KLM
7,7
Good
1 405 reviews
Check prices

Food

7,3

Entertainment

7,1

Boarding

7,8

Overall

7,7

Crew

8,4

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7,4
Good
9 001 reviews
KLM
7,7
Good
1 405 reviews
Check prices

Food

7,3

Entertainment

7,1

Boarding

7,8

Overall

7,7

Crew

8,4

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Turkish Airlines
7,3
Good
4 035 reviews
KLM
7,7
Good
1 405 reviews
Check prices

Food

7,3

Entertainment

7,1

Boarding

7,8

Overall

7,7

Crew

8,4

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6,7
Okay
7 495 reviews
KLM
7,7
Good
1 405 reviews
Check prices

Food

7,3

Entertainment

7,1

Boarding

7,8

Overall

7,7

Crew

8,4

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R28 042, United Airlines can have you in Panama from South Africa in 23h 31m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R8 249). Flying from South Africa to Panama in September is currently the most expensive (average of R22 043). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Cape Town to Guatemala City flights
OR Tambo to Panama City flights
Cape Town to Panama City flights
OR Tambo to Liberia flights
OR Tambo to San José flights
Cape Town to San José flights

Top 5 airlines flying from South Africa to Panama

Discover the top 5 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 5 November 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 358AverageR22 514FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR19 388AverageR22 921FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapestR23 506AverageR26 991FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR24 272AverageR27 864FlexibilityNo cancel feeOn-time77%
Search Air France flights
Turkish AirlinesCheapestR36 703AverageR38 411FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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