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Cheap flights from South Africa to Panama from R10 906

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Aug 27 — Sep 31
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 July 2026.

Sat 22/815:50
CPT
-
PTY
1 stop22h 06m
Multiple Airlines
Sat 29/818:46
PTY
-
CPT
1 stop33h 09m
Multiple Airlines
Deal found 25/7R19 136
Mon 24/87:30
JNB
-
PTY
3 stops32h 45m
Multiple Airlines
Mon 31/84:25
PTY
-
JNB
2 stops24h 30m
Multiple Airlines
Deal found 27/7R20 090
Sun 1/1122:00
JNB
-
PTY
2 stops38h 33m
United Airlines
Sun 22/119:11
PTY
-
JNB
2 stops26h 24m
United Airlines
Deal found 25/7R20 341
Mon 24/822:00
JNB
-
PTY
2 stops27h 37m
United Airlines
Mon 31/812:56
PTY
-
JNB
2 stops70h 34m
United Airlines
Deal found 27/7R20 357
Wed 16/918:25
CPT
-
PTY
2 stops32h 06m
United Airlines
Wed 30/918:06
PTY
-
CPT
3 stops64h 04m
United Airlines
Deal found 27/7R20 976
Tue 8/1222:00
JNB
-
PTY
1 stop29h 02m
United Airlines
Wed 30/1223:55
PTY
-
JNB
1 stop35h 40m
United Airlines
Deal found 26/7R23 753
Wed 9/99:00
CPT
-
PTY
3 stops31h 15m
Multiple Airlines
Wed 16/94:25
PTY
-
CPT
2 stops23h 30m
Multiple Airlines
Deal found 26/7R25 359
Mon 7/96:00
CPT
-
PTY
2 stops31h 26m
Multiple Airlines
Mon 14/919:03
PTY
-
CPT
1 stop28h 42m
Multiple Airlines
Deal found 25/7R27 885
Mon 7/923:00
CPT
-
PTY
1 stop24h 50m
KLM
Mon 14/918:50
PTY
-
CPT
1 stop28h 00m
KLM
Deal found 25/7R27 952
Wed 9/916:35
CPT
-
PTY
2 stops32h 55m
Turkish Airlines
Wed 16/922:20
PTY
-
CPT
1 stop30h 30m
Turkish Airlines
Deal found 26/7R29 340
Wed 9/97:40
CPT
-
PTY
1 stop40h 10m
KLM
Wed 16/918:50
PTY
-
CPT
1 stop28h 00m
KLM
Deal found 26/7R29 390

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 28 July 2026.

Round-trip from

R19 136

One-way from

R10 906

Popular in

December

Cheapest in

April

Average price

R21 394
22/8-29/8
  • 22/8-29/8
  • 2 total stops
  • 55h 15m total
  • South Africa to Panama
Search Deals
3/10
  • 3/10
  • 3 total stops
  • 38h 55m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (R6 066 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (R7 817 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 28 July 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 1/11

22:00-5:33

2 stops38h 33m

Panama City Tocumen Intl

Sun 22/11

9:11-18:35

2 stops26h 24m

R20 341

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 24/8

22:00-18:37

2 stops27h 37m

Panama City Tocumen Intl

Mon 31/8

12:56-18:30

2 stops70h 34m

R20 357

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 22/8

15:50-14:15

2 stops29h 25m

Panama City Tocumen Intl

Sat 29/8

17:55-10:55

2 stops34h 00m

R20 608

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 16/9

15:20-19:31

2 stops35h 11m

Panama City Tocumen Intl

Wed 30/9

8:11-15:20

2 stops48h 09m

R20 976

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 8/12

22:00-20:02

1 stop29h 02m

Panama City Tocumen Intl

Wed 30/12

23:55-18:35

1 stop35h 40m

R23 753
Fastest return journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 9/9

9:00-9:15

3 stops31h 15m

Panama City Tocumen Intl

Wed 16/9

4:25-10:55

2 stops23h 30m

R25 359

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 9/9

16:35-18:30

2 stops32h 55m

Panama City Tocumen Intl

Wed 16/9

22:20-11:50

1 stop30h 30m

R29 340

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 9/9

7:40-16:50

1 stop40h 10m

Panama City Tocumen Intl

Wed 16/9

18:50-5:50

1 stop28h 00m

R29 390

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 9/8

9:55-14:15

3 stops35h 20m

Panama City Tocumen Intl

Thu 13/8

4:25-17:20

3 stops29h 55m

R29 892

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 9/8

20:00-20:27

3 stops31h 27m

Panama City Tocumen Intl

Thu 13/8

22:29-17:10

2 stops35h 41m

R32 803

Flights are sorted by cheapest return flights first.

Deals found on 28/7

Showing 1-10 of 22 resultsSorted by cheapest first
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3

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 871). Flying from South Africa to Panama in December is currently the most expensive (average of R26 580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 28 July 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 550 reviews
Check prices

Overall

7,8

Comfort

7,7

Boarding

7,8

Food

7,3

Crew

8,4

Entertainment

7,2

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 550 reviews
KLM
7,8
Good
1 550 reviews
Check prices

Overall

7,8

Comfort

7,7

Boarding

7,8

Food

7,3

Crew

8,4

Entertainment

7,2

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,5
Good
1 627 reviews
KLM
7,8
Good
1 550 reviews
Check prices

Overall

7,8

Comfort

7,7

Boarding

7,8

Food

7,3

Crew

8,4

Entertainment

7,2

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
10 045 reviews
KLM
7,8
Good
1 550 reviews
Check prices

Overall

7,8

Comfort

7,7

Boarding

7,8

Food

7,3

Crew

8,4

Entertainment

7,2

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6,7
Okay
8 128 reviews
KLM
7,8
Good
1 550 reviews
Check prices

Overall

7,8

Comfort

7,7

Boarding

7,8

Food

7,3

Crew

8,4

Entertainment

7,2

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R20 341, United Airlines can have you in Panama from South Africa in 38h 33m. Airlines will cover a distance of 12194 km.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 871). Flying from South Africa to Panama in December is currently the most expensive (average of R26 580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Guatemala City flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to Liberia flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 28 July 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR19 248AverageR24 721FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR19 329AverageR21 356FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Air FranceCheapestR24 251AverageR24 986FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR25 283AverageR27 999FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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