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Cheap flights from South Africa to Panama from R11 568

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/3. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
mar. 21 — mar. 281
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 19 febrero 2026.

lun. 1/622:00
JNB
-
PTY
2 stops29h 27m
United Airlines
sáb. 1/87:55
PTY
-
JNB
2 stops27h 35m
United Airlines
Deal found 18/2R20 846
sáb. 4/414:00
CPT
-
PTY
2 stops36h 45m
Multiple Airlines
sáb. 11/418:50
PTY
-
CPT
1 stop28h 00m
Multiple Airlines
Deal found 18/2R23 457
mié. 25/219:45
JNB
-
PTY
2 stops46h 01m
United Airlines
jue. 5/39:11
PTY
-
JNB
2 stops26h 24m
United Airlines
Deal found 19/2R23 489
jue. 2/418:25
CPT
-
PTY
2 stops56h 20m
Multiple Airlines
jue. 9/418:50
PTY
-
CPT
1 stop43h 35m
Multiple Airlines
Deal found 15/2R23 794
jue. 19/311:10
JNB
-
PTY
2 stops33h 50m
Multiple Airlines
dom. 22/317:50
PTY
-
JNB
2 stops30h 55m
Multiple Airlines
Deal found 16/2R23 906
jue. 19/30:45
JNB
-
PTY
2 stops38h 09m
Multiple Airlines
vie. 27/318:54
PTY
-
JNB
1 stop34h 46m
Multiple Airlines
Deal found 18/2R24 403
mié. 11/319:35
JNB
-
PTY
2 stops49h 45m
American Airlines
dom. 19/413:49
PTY
-
JNB
2 stops36h 36m
American Airlines
Deal found 18/2R24 771
mié. 11/323:59
JNB
-
PTY
1 stop23h 31m
KLM
dom. 19/418:50
PTY
-
JNB
1 stop43h 30m
KLM
Deal found 18/2R25 204
sáb. 9/59:50
JNB
-
PTY
2 stops39h 50m
Multiple Airlines
mar. 30/620:25
PTY
-
JNB
2 stops52h 55m
Multiple Airlines
Deal found 19/2R25 348
mié. 11/319:20
JNB
-
PTY
2 stops28h 10m
Multiple Airlines
dom. 19/418:50
PTY
-
JNB
1 stop43h 30m
Multiple Airlines
Deal found 18/2R25 524
lun. 7/919:00
JNB
-
PTY
2 stops32h 41m
United Airlines
jue. 1/109:13
PTY
-
JNB
2 stops26h 17m
United Airlines
Deal found 17/2R25 556
mar. 10/322:00
JNB
-
PTY
2 stops47h 20m
American Airlines
dom. 22/313:40
PTY
-
JNB
2 stops37h 45m
American Airlines
Deal found 18/2R25 749

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 19 febrero 2026.

Round-trip from

R20 846

One-way from

R11 568

Popular in

December

Cheapest in

May

Average price

R20 653
United Airlines
  • United Airlines
  • 1/6-1/8
  • 4 total stops
  • 57h 02m total
  • South Africa to Panama
Search Deals
31/3
  • 31/3
  • 3 total stops
  • 40h 35m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (R18 336 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R4 849 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 19 febrero 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

lun. 1/6

22:00-20:27

2 stops29h 27m

Panama City Tocumen Intl

sáb. 1/8

7:55-18:30

2 stops27h 35m

R20 846

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

sáb. 4/4

14:00-19:45

2 stops36h 45m

Panama City Tocumen Intl

sáb. 11/4

18:50-5:50

1 stop28h 00m

R23 457

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

jue. 2/4

18:25-19:45

2 stops56h 20m

Panama City Tocumen Intl

jue. 9/4

18:50-21:25

1 stop43h 35m

R23 794

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

jue. 19/3

11:10-14:00

2 stops33h 50m

Panama City Tocumen Intl

dom. 22/3

17:50-7:45

2 stops30h 55m

R23 906

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

jue. 19/3

0:45-7:54

2 stops38h 09m

Panama City Tocumen Intl

vie. 27/3

18:54-12:40

1 stop34h 46m

R24 403

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

mié. 11/3

19:35-14:20

2 stops49h 45m

Panama City Tocumen Intl

dom. 19/4

13:49-9:25

2 stops36h 36m

R24 771

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

mié. 11/3

23:59-16:30

1 stop23h 31m

Panama City Tocumen Intl

dom. 19/4

18:50-21:20

1 stop43h 30m

R25 204

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

sáb. 9/5

9:50-18:40

2 stops39h 50m

Panama City Tocumen Intl

mar. 30/6

20:25-8:20

2 stops52h 55m

R25 348

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

mar. 10/3

19:20-16:30

2 stops28h 10m

Panama City Tocumen Intl

dom. 22/3

22:20-12:10

1 stop30h 50m

R26 101

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

sáb. 9/5

18:00-20:42

2 stops33h 42m

Panama City Tocumen Intl

mar. 30/6

21:55-11:05

1 stop30h 10m

R26 261

Flights are sorted by cheapest return flights first.

Deals found on 17/2

Showing 1-10 of 16 results
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 611). Flying from South Africa to Panama in September is currently the most expensive (average of R20 237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 19 febrero 2026.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 458 reviews
Check prices

Food

7,3

Overall

7,7

Crew

8,4

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,7
Good
1 458 reviews
KLM
7,7
Good
1 458 reviews
Check prices

Food

7,3

Overall

7,7

Crew

8,4

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,4
Good
1 533 reviews
KLM
7,7
Good
1 458 reviews
Check prices

Food

7,3

Overall

7,7

Crew

8,4

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 321 reviews
KLM
7,7
Good
1 458 reviews
Check prices

Food

7,3

Overall

7,7

Crew

8,4

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6,7
Okay
7 753 reviews
KLM
7,7
Good
1 458 reviews
Check prices

Food

7,3

Overall

7,7

Crew

8,4

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R25 204, United Airlines can have you in Panama from South Africa in 23h 31m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 611). Flying from South Africa to Panama in September is currently the most expensive (average of R20 237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to San José flights
Cape Town to Guatemala City flights
OR Tambo to Liberia flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 19 febrero 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR17 813AverageR20 294FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR18 351AverageR20 867FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR22 200AverageR25 174FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 229AverageR24 387FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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