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Cheap flights from South Africa to Panama from R16 147

JNB — PTY
Nov 24 — Dec 11
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama

Sun 1/1122:00 -
2 stops29h 27m
Sun 8/1122:29 -
2 stops37h 06m
Deal found 25/10R20 756
Sat 24/1022:00 -
2 stops29h 27m
Sat 31/1022:29 -
2 stops37h 06m
Deal found 23/10R20 822
Fri 23/1020:00 -
2 stops29h 37m
Fri 30/109:30 -
2 stops47h 40m
Deal found 22/10R20 938
Thu 22/1019:50 -
1 stop30h 41m
Thu 29/1022:29 -
2 stops36h 31m
Deal found 21/10R20 955
Tue 8/1210:25 -
2 stops41h 10m
Wed 30/1223:55 -
1 stop35h 40m
Deal found 25/10R21 369
Thu 19/1118:50 -
1 stop32h 15m
Mon 23/1122:00 -
1 stop41h 25m
Deal found 23/10R24 817
Fri 27/110:20 -
1 stop26h 45m
Fri 25/1222:00 -
1 stop41h 25m
Deal found 20/10R25 215
Tue 17/110:55 -
2 stops47h 15m
Sun 22/1118:50 -
1 stop45h 10m
Deal found 24/10R26 591
Wed 18/1120:50 -
2 stops29h 48m
Sun 22/1119:28 -
2 stops37h 42m
Deal found 24/10R32 742
Thu 22/1023:15 -
3 stops72h 12m
Thu 29/107:55 -
2 stops39h 30m
Deal found 21/10R34 681

Find flight deals from South Africa to Panama

Round-trip from

R20 888

One-way from

R16 147

Popular in

August

Cheapest in

April

Average price

R22 795
United Airlines
  • United Airlines
  • 5/4-30/4
  • 4 total stops
  • 71h 37m total
  • South Africa to Panama
Search Deals
1/11-31/12
  • 1/11-31/12
  • 3 total stops
  • 43h 46m total
  • South Africa to Panama
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R5 853 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Sun 1/11

18:50-7:36

3 stops43h 46m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R16 147

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 10/11

18:50-6:37

3 stops42h 47m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R16 147
Fastest return journey

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 10/11

18:50-20:05

1 stop32h 15m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R18 302

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Wed 9/12

20:50-10:33

2 stops44h 43m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R20 491

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Mon 5/4

22:00-18:37

2 stops27h 37m

Panama City Tocumen Intl

Fri 30/4

15:30-18:30

2 stops44h 00m

R20 888

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 8/12

10:25-20:35

2 stops41h 10m

Panama City Tocumen Intl

Wed 30/12

11:35-18:35

2 stops48h 00m

R21 369

JohannesburgDavid

JNB Johannesburg OR Tambo - DAV David Enrique Malek

JNBDAV

Johannesburg OR Tambo

Sun 1/11

16:40-18:59

3 stops57h 19m

David Enrique Malek

Wed 31/12

0:00-7:00

Nonstop0h 00m

R22 281

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Thu 19/11

18:50-17:10

2 stops29h 20m

Panama City Tocumen Intl

Mon 23/11

22:00-22:25

1 stop41h 25m

R24 983

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Tue 17/11

0:55-17:10

2 stops47h 15m

Panama City Tocumen Intl

Sun 22/11

18:50-23:00

1 stop45h 10m

R26 591

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Wed 18/11

20:50-19:38

2 stops29h 48m

Panama City Tocumen Intl

Sun 22/11

19:28-16:10

2 stops37h 42m

R32 742

Flights are sorted by cheapest return flights first.

Deals found on 20/10

Showing 1-10 of 11 resultsSorted by cheapest first
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 738). Flying from South Africa to Panama in August is currently the most expensive (average of R26 757). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Check out reviews from past customers who have flown with United Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,3
Good
10 436 reviews
Check prices

Food

6,7

Entertainment

7,1

Boarding

7,7

Comfort

7,3

Crew

8,1

Overall

7,3

Reviews

1 / 20
4,0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7,3
Good
10 436 reviews
United Airlines
7,3
Good
10 436 reviews
Check prices

Food

6,7

Entertainment

7,1

Boarding

7,7

Comfort

7,3

Crew

8,1

Overall

7,3

Reviews

1 / 20
4,0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

  • How long is the flight from South Africa to Panama?

    For as low as R20 888, United Airlines can have you in Panama from South Africa in 27h 37m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 738). Flying from South Africa to Panama in August is currently the most expensive (average of R26 757). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Africa to Panama

OR Tambo to Panama City flights
Cape Town to Panama City flights
Cape Town to San José flights
Cape Town to Guatemala City flights
OR Tambo to Liberia flights
OR Tambo to San José flights

Top airline flying from South Africa to Panama

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR19 213AverageR21 261FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

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Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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