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Cheap flights from South Africa to Panama from R11 690

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/8. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Aug 17 — Aug 241
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 July 2026.

Mon 10/85:45
JNB
-
PTY
3 stops39h 30m
Multiple Airlines
Mon 17/84:25
PTY
-
JNB
3 stops40h 50m
Multiple Airlines
Deal found 13/7R19 719
Wed 22/722:00
JNB
-
PTY
2 stops29h 35m
United Airlines
Wed 5/815:30
PTY
-
JNB
2 stops44h 00m
United Airlines
Deal found 14/7R20 312
Thu 10/919:50
CPT
-
PTY
1 stop30h 41m
United Airlines
Thu 24/912:04
PTY
-
CPT
2 stops46h 06m
United Airlines
Deal found 14/7R20 312
Thu 10/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Thu 24/98:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Deal found 14/7R20 378
Fri 18/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Sat 26/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Deal found 16/7R20 428
Fri 18/922:00
JNB
-
PTY
2 stops39h 37m
United Airlines
Sun 27/98:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Deal found 16/7R20 477
Sun 19/722:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Sat 8/87:55
PTY
-
JNB
2 stops27h 35m
United Airlines
Deal found 13/7R20 494
Wed 22/722:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Thu 24/99:39
PTY
-
JNB
2 stops25h 51m
United Airlines
Deal found 12/7R20 510
Fri 18/922:00
JNB
-
PTY
2 stops38h 33m
United Airlines
Thu 1/1022:29
PTY
-
JNB
2 stops37h 01m
United Airlines
Deal found 16/7R20 576
Sat 25/722:00
JNB
-
PTY
1 stop37h 04m
United Airlines
Wed 5/822:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Deal found 13/7R20 939
Sat 19/915:05
JNB
-
PTY
2 stops35h 26m
United Airlines
Mon 28/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Deal found 16/7R21 054
Sat 8/815:05
JNB
-
PTY
2 stops35h 26m
United Airlines
Sat 15/818:06
PTY
-
JNB
2 stops41h 24m
United Airlines
Deal found 16/7R21 087

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 18 July 2026.

Round-trip from

R19 719

One-way from

R11 690

Popular in

December

Cheapest in

April

Average price

R20 395
10/8-17/8
  • 10/8-17/8
  • 6 total stops
  • 80h 20m total
  • South Africa to Panama
Search Deals
16/8
  • 16/8
  • 3 total stops
  • 56h 55m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (R10 713 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (R8 808 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 18 July 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 10/9

19:50-19:31

1 stop30h 41m

Panama City Tocumen Intl

Thu 24/9

12:04-17:10

2 stops46h 06m

R20 312

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 30/8

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Sun 6/9

22:29-18:30

2 stops37h 01m

R20 477

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 18/9

22:00-6:37

2 stops39h 37m

Panama City Tocumen Intl

Sun 27/9

8:11-18:30

2 stops27h 19m

R20 477

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 18/8

22:00-18:37

2 stops27h 37m

Panama City Tocumen Intl

Wed 26/8

9:39-18:30

2 stops25h 51m

R22 720

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 4/8

22:00-18:37

2 stops27h 37m

Panama City Tocumen Intl

Mon 17/8

19:25-18:30

2 stops40h 05m

R22 736

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 13/8

18:25-4:04

2 stops40h 39m

Panama City Tocumen Intl

Fri 18/9

12:04-15:20

2 stops44h 16m

R22 769

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 8/12

22:00-20:02

1 stop29h 02m

Panama City Tocumen Intl

Wed 30/12

23:55-18:35

1 stop35h 40m

R25 671

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 24/11

22:00-20:02

1 stop29h 02m

Panama City Tocumen Intl

Thu 24/12

8:55-18:35

2 stops26h 40m

R28 094

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 4/12

22:00-20:02

1 stop29h 02m

Panama City Tocumen Intl

Sun 27/12

23:55-18:35

1 stop35h 40m

R28 523

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 10/9

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Thu 24/9

18:50-21:25

1 stop43h 35m

R28 672

Flights are sorted by cheapest return flights first.

Deals found on 13/7

Showing 1-10 of 23 resultsSorted by cheapest first
1
2
3

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 657). Flying from South Africa to Panama in December is currently the most expensive (average of R26 660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 18 July 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 541 reviews
Check prices

Entertainment

7,2

Boarding

7,8

Food

7,3

Comfort

7,7

Crew

8,4

Overall

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 541 reviews
KLM
7,8
Good
1 541 reviews
Check prices

Entertainment

7,2

Boarding

7,8

Food

7,3

Comfort

7,7

Crew

8,4

Overall

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,5
Good
1 626 reviews
KLM
7,8
Good
1 541 reviews
Check prices

Entertainment

7,2

Boarding

7,8

Food

7,3

Comfort

7,7

Crew

8,4

Overall

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 999 reviews
KLM
7,8
Good
1 541 reviews
Check prices

Entertainment

7,2

Boarding

7,8

Food

7,3

Comfort

7,7

Crew

8,4

Overall

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6,7
Okay
8 121 reviews
KLM
7,8
Good
1 541 reviews
Check prices

Entertainment

7,2

Boarding

7,8

Food

7,3

Comfort

7,7

Crew

8,4

Overall

7,8

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R28 672, United Airlines can have you in Panama from South Africa in 24h 35m. Airlines will cover a distance of 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 657). Flying from South Africa to Panama in December is currently the most expensive (average of R26 660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
OR Tambo to San José flights
Cape Town to Panama City flights
OR Tambo to Liberia flights
Cape Town to Guatemala City flights
Cape Town to San José flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 18 July 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR18 972AverageR22 697FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR19 051AverageR20 921FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Air FranceCheapestR23 902AverageR24 627FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR24 920AverageR27 597FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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