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Cheap flights from South Africa to Panama from R11 222

JNB — PTY
Sep 26 — Oct 31
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama

Mon 9/1122:00 -
2 stops29h 37m
Mon 16/1112:04 -
3 stops71h 31m
Deal found 25/8R19 925
Mon 24/819:50 -
2 stops29h 47m
Mon 31/89:45 -
2 stops48h 35m
Deal found 23/8R20 658
Tue 27/1019:45 -
2 stops31h 49m
Tue 3/1122:29 -
2 stops37h 06m
Deal found 24/8R20 929
Mon 30/1122:00 -
2 stops39h 13m
Tue 29/1216:41 -
2 stops57h 59m
Deal found 22/8R21 440
Wed 28/1019:35 -
2 stops48h 27m
Tue 3/1115:13 -
2 stops36h 12m
Deal found 24/8R22 029
Tue 27/1019:55 -
1 stop30h 50m
Tue 3/1121:30 -
1 stop30h 20m
Deal found 24/8R22 045
Tue 8/1222:00 -
2 stops28h 38m
Wed 30/1216:41 -
2 stops42h 54m
Deal found 26/8R22 253
Mon 24/823:00 -
1 stop24h 50m
Mon 31/818:50 -
1 stop28h 00m
Deal found 23/8R27 481
Thu 8/1016:35 -
1 stop34h 50m
Mon 12/1022:20 -
1 stop30h 30m
Deal found 21/8R29 107
Thu 8/1019:50 -
2 stops29h 47m
Mon 12/109:13 -
1 stop23h 07m
Deal found 24/8R31 530
Mon 24/815:50 -
3 stops32h 10m
Mon 31/84:25 -
3 stops33h 05m
Deal found 23/8R37 730

Find flight deals from South Africa to Panama

Round-trip from

R19 925

One-way from

R11 222

Popular in

October

Cheapest in

April

Average price

R25 393
United Airlines
  • United Airlines
  • 9/11-16/11
  • 5 total stops
  • 101h 08m total
  • South Africa to Panama
Search Deals
26/9
  • 26/9
  • 3 total stops
  • 52h 35m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 0% potential increase in price (R2 083 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R5 664 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Mon 9/11

22:00-20:27

2 stops29h 27m

Panama City Tocumen Intl

Mon 16/11

10:00-18:35

1 stop25h 35m

R19 925

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 27/10

19:45-20:34

2 stops31h 49m

Panama City Tocumen Intl

Tue 3/11

22:29-18:35

2 stops37h 06m

R20 929

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Mon 30/11

22:00-6:13

2 stops39h 13m

Panama City Tocumen Intl

Tue 29/12

16:41-9:40

2 stops57h 59m

R21 440

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 8/12

22:00-5:33

2 stops38h 33m

Panama City Tocumen Intl

Wed 30/12

23:55-18:35

1 stop35h 40m

R26 588

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Thu 8/10

16:35-20:25

1 stop34h 50m

Panama City Tocumen Intl

Mon 12/10

22:20-11:50

1 stop30h 30m

R29 107

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Thu 19/11

18:50-20:05

1 stop32h 15m

Panama City Tocumen Intl

Mon 23/11

22:00-22:25

1 stop41h 25m

R30 302

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Sat 19/9

19:00-20:31

2 stops32h 31m

Panama City Tocumen Intl

Sat 26/9

18:27-18:30

2 stops41h 03m

R30 382

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Thu 8/10

19:50-20:41

2 stops31h 51m

Panama City Tocumen Intl

Mon 12/10

18:06-17:10

2 stops64h 04m

R31 530
Fastest return journey

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Thu 19/11

22:00-17:08

2 stops26h 08m

Panama City Tocumen Intl

Mon 23/11

10:00-18:35

1 stop25h 35m

R31 562
Cheapest one-way

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Sat 26/9

16:40-14:15

3 stops52h 35m

R11 222

Flights are sorted by cheapest return flights first.

Deals found on 25/8

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 171). Flying from South Africa to Panama in December is currently the most expensive (average of R25 488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Check out reviews from past customers who have flown with KLM,United Airlines, andBritish Airways from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 565 reviews
Check prices

Entertainment

7,2

Overall

7,8

Boarding

7,8

Comfort

7,7

Crew

8,4

Food

7,3

Reviews

1 / 20
8,0
Excellent

Meghana,Aug 2026

QRO - ATL

It was a good one. They were very friendly and helpful
KLM
7,8
Good
1 565 reviews
KLM
7,8
Good
1 565 reviews
Check prices

Entertainment

7,2

Overall

7,8

Boarding

7,8

Comfort

7,7

Crew

8,4

Food

7,3

Reviews

1 / 20
8,0
Excellent

Meghana,Aug 2026

QRO - ATL

It was a good one. They were very friendly and helpful
United Airlines
7,4
Good
10 127 reviews
KLM
7,8
Good
1 565 reviews
Check prices

Entertainment

7,2

Overall

7,8

Boarding

7,8

Comfort

7,7

Crew

8,4

Food

7,3

Reviews

1 / 20
8,0
Excellent

Meghana,Aug 2026

QRO - ATL

It was a good one. They were very friendly and helpful
British Airways
6,7
Okay
8 194 reviews
KLM
7,8
Good
1 565 reviews
Check prices

Entertainment

7,2

Overall

7,8

Boarding

7,8

Comfort

7,7

Crew

8,4

Food

7,3

Reviews

1 / 20
8,0
Excellent

Meghana,Aug 2026

QRO - ATL

It was a good one. They were very friendly and helpful

Related info for your journey

  • How long is the flight from South Africa to Panama?

    For as low as R19 925, United Airlines can have you in Panama from South Africa in 29h 27m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, April is the cheapest month in which you can book a flight from South Africa to Panama (average of R14 171). Flying from South Africa to Panama in December is currently the most expensive (average of R25 488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Africa to Panama

OR Tambo to Panama City flights
OR Tambo to San José flights
Cape Town to Panama City flights
OR Tambo to Liberia flights
Cape Town to Guatemala City flights
Cape Town to San José flights

Top 3 airlines flying from South Africa to Panama

AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR18 342AverageR20 486FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR18 419AverageR20 347FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR24 093AverageR25 664FlexibilityNo cancel feeOn-time75%
Search KLM flights

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How does Cheapflights help users find flights from South Africa to Panama?

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Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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