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Cheap flights from South Africa to Panama from R14 609

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/5. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Jun 13 — Jun 201
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 May 2026.

Thu 11/614:50
JNB
-
PTY
1 stop26h 08m
Multiple Airlines
Wed 17/612:00
PTY
-
JNB
1 stop16h 55m
Multiple Airlines
Deal found 13/5R19 901
Wed 18/1110:25
JNB
-
PTY
2 stops40h 37m
United Airlines
Thu 26/1110:00
PTY
-
JNB
1 stop25h 35m
United Airlines
Deal found 10/5R21 182
Tue 17/1119:55
JNB
-
PTY
1 stop30h 50m
Air Europa
Thu 26/1121:30
PTY
-
JNB
1 stop30h 20m
Air Europa
Deal found 10/5R22 316
Thu 19/1119:55
JNB
-
PTY
1 stop30h 50m
Air Europa
Sun 22/1121:30
PTY
-
JNB
1 stop30h 20m
Air Europa
Deal found 12/5R22 711
Thu 19/1119:55
JNB
-
PTY
1 stop30h 50m
Air Europa
Thu 26/1121:30
PTY
-
JNB
1 stop30h 20m
Air Europa
Deal found 10/5R22 809
Tue 17/1122:00
JNB
-
PTY
2 stops29h 27m
United Airlines
Wed 25/1110:00
PTY
-
JNB
1 stop25h 35m
United Airlines
Deal found 10/5R26 556
Tue 17/1119:55
JNB
-
PTY
1 stop30h 50m
Multiple Airlines
Tue 24/1115:37
PTY
-
JNB
2 stops36h 13m
Multiple Airlines
Deal found 10/5R26 589
Sun 26/720:00
CPT
-
PTY
1 stop31h 35m
United Airlines
Sun 2/822:55
PTY
-
CPT
2 stops33h 25m
United Airlines
Deal found 10/5R30 287
Sun 26/716:35
CPT
-
PTY
1 stop34h 50m
Turkish Airlines
Sun 2/820:05
PTY
-
CPT
1 stop32h 45m
Turkish Airlines
Deal found 13/5R32 259
Sat 20/619:50
CPT
-
PTY
1 stop30h 41m
United Airlines
Fri 26/610:00
PTY
-
CPT
2 stops46h 20m
United Airlines
Deal found 10/5R33 425
Sat 20/623:15
CPT
-
PTY
2 stops51h 30m
KLM
Fri 26/621:55
PTY
-
CPT
2 stops40h 30m
KLM
Deal found 10/5R33 458
Fri 26/618:25
CPT
-
PTY
2 stops29h 25m
KLM
Fri 3/721:55
PTY
-
CPT
2 stops40h 30m
KLM
Deal found 12/5R37 665

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 14 May 2026.

Round-trip from

R19 901

One-way from

R14 609

Popular in

December

Cheapest in

April

Average price

R20 509
11/6-17/6
  • 11/6-17/6
  • 2 total stops
  • 43h 03m total
  • South Africa to Panama
Search Deals
24/5
  • 24/5
  • 3 total stops
  • 38h 55m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (R7 119 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R6 932 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 14 May 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 11/6

14:50-14:15

2 stops30h 25m

Panama City Tocumen Intl

Wed 17/6

4:25-11:55

2 stops24h 30m

R23 122

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 22/6

10:25-19:31

2 stops40h 06m

Panama City Tocumen Intl

Fri 3/7

9:45-18:30

1 stop25h 45m

R26 836

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 6/6

23:15-19:45

2 stops51h 30m

Panama City Tocumen Intl

Sat 13/6

18:50-21:25

1 stop43h 35m

R28 939

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 26/7

20:00-20:35

1 stop31h 35m

Panama City Tocumen Intl

Sun 2/8

22:55-15:20

2 stops33h 25m

R30 287

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 16/7

18:00-16:50

2 stops29h 50m

Panama City Tocumen Intl

Mon 27/7

16:25-11:05

2 stops35h 40m

R31 864

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 26/7

16:35-20:25

1 stop34h 50m

Panama City Tocumen Intl

Sun 2/8

20:05-11:50

1 stop32h 45m

R32 259

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 13/9

19:10-6:40

2 stops42h 30m

Panama City Tocumen Intl

Thu 17/9

15:18-10:15

2 stops35h 57m

R32 817

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 22/6

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Fri 3/7

21:55-11:05

1 stop30h 10m

R33 064

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 20/6

19:50-19:31

1 stop30h 41m

Panama City Tocumen Intl

Fri 26/6

10:00-15:20

2 stops46h 20m

R33 425

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 20/6

23:15-19:45

2 stops51h 30m

Panama City Tocumen Intl

Fri 26/6

21:55-21:25

2 stops40h 30m

R33 458

Flights are sorted by cheapest return flights first.

Deals found on 11/5

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 984). Flying from South Africa to Panama in September is currently the most expensive (average of R19 128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 14 May 2026.
Check out reviews from past customers who have flown with KLM,Air France, andLATAM Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 517 reviews
Check prices

Boarding

7,8

Comfort

7,7

Overall

7,8

Entertainment

7,2

Crew

8,4

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7,8
Good
1 517 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Boarding

7,8

Comfort

7,7

Overall

7,8

Entertainment

7,2

Crew

8,4

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air France
7,4
Good
1 589 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Boarding

7,8

Comfort

7,7

Overall

7,8

Entertainment

7,2

Crew

8,4

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
LATAM Airlines
7,4
Good
1 923 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Boarding

7,8

Comfort

7,7

Overall

7,8

Entertainment

7,2

Crew

8,4

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
United Airlines
7,4
Good
9 718 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Boarding

7,8

Comfort

7,7

Overall

7,8

Entertainment

7,2

Crew

8,4

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
British Airways
6,7
Okay
7 980 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Boarding

7,8

Comfort

7,7

Overall

7,8

Entertainment

7,2

Crew

8,4

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R26 836, United Airlines can have you in Panama from South Africa in 40h 06m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 984). Flying from South Africa to Panama in September is currently the most expensive (average of R19 128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to Guatemala City flights
Cape Town to San José flights
OR Tambo to Liberia flights

Top 5 airlines flying from South Africa to Panama

Discover the top 5 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 14 May 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapestR7 900AverageR14 611FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights
United AirlinesCheapestR18 876AverageR20 876FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR18 910AverageR21 262FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapestR23 824AverageR25 117FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR24 703AverageR26 458FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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