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Cheap flights from South Africa to Panama from R19 536

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Jan 19 — Jan 261
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Best flights from South Africa to Panama
Discover carefully curated flight deals from South Africa to Panama that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 20 December 2025.

Tue 10/222:00JNB - PTY
2 stops38h 33mUnited Airlines
Sat 21/29:30PTY - JNB
2 stops26h 05mUnited Airlines
Deal found 18/12R19 536
Mon 2/222:00JNB - PTY
2 stops26h 08mLufthansa
Mon 9/28:55PTY - JNB
2 stops26h 40mLufthansa
Deal found 19/12R20 022
Tue 20/19:25JNB - PTY
2 stops28h 02mMultiple Airlines
Wed 24/621:40PTY - JNB
1 stop26h 25mMultiple Airlines
Deal found 18/12R20 658
Tue 20/123:59JNB - PTY
1 stop26h 56mKLM
Wed 24/618:50PTY - JNB
1 stop43h 45mKLM
Deal found 18/12R26 204
Fri 13/222:00JNB - PTY
2 stops29h 35mUnited Airlines
Fri 27/28:16PTY - JNB
2 stops27h 19mUnited Airlines
Deal found 18/12R21 982
Tue 20/119:45JNB - PTY
2 stops40h 48mUnited Airlines
Wed 24/618:06PTY - JNB
2 stops41h 24mUnited Airlines
Deal found 18/12R22 183
Sat 28/312:40CPT - PTY
2 stops28h 30mMultiple Airlines
Fri 10/422:05PTY - CPT
2 stops25h 40mMultiple Airlines
Deal found 19/12R26 305
Sat 28/38:00CPT - PTY
1 stop39h 50mKLM
Fri 10/418:50PTY - CPT
2 stops43h 55mKLM
Deal found 19/12R28 634
Thu 5/220:50CPT - PTY
2 stops27h 17mUnited Airlines
Mon 9/28:16PTY - CPT
2 stops24h 54mUnited Airlines
Deal found 18/12R31 364

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 20 December 2025.

Round-trip from

R19 536

Popular in

December

Cheapest in

January

Average price

R28 499
United Airlines
  • United Airlines
  • 10/2-21/2
  • 4 total stops
  • 64h 38m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (R7 357 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R6 532 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 20 December 2025.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 10/2

22:00-5:33

2 stops38h 33m

Panama City Tocumen Intl

Sat 21/2

9:30-18:35

2 stops26h 05m

R19 536

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 2/2

22:00-17:08

2 stops26h 08m

Panama City Tocumen Intl

Mon 9/2

8:55-18:35

2 stops26h 40m

R20 022

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 20/1

9:25-6:27

2 stops28h 02m

Panama City Tocumen Intl

Wed 24/6

21:40-7:05

1 stop26h 25m

R20 658

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 13/2

22:00-20:35

2 stops29h 35m

Panama City Tocumen Intl

Fri 27/2

8:16-18:35

2 stops27h 19m

R21 982

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 20/1

19:45-5:33

2 stops40h 48m

Panama City Tocumen Intl

Wed 24/6

18:06-18:30

2 stops41h 24m

R22 183

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 20/1

23:59-19:55

1 stop26h 56m

Panama City Tocumen Intl

Wed 24/6

18:50-21:35

1 stop43h 45m

R26 204

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 28/3

12:40-10:10

2 stops28h 30m

Panama City Tocumen Intl

Fri 10/4

22:05-6:45

2 stops25h 40m

R26 305

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sat 28/3

8:00-16:50

1 stop39h 50m

Panama City Tocumen Intl

Fri 10/4

18:50-21:45

2 stops43h 55m

R28 634

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 5/2

20:50-17:07

2 stops27h 17m

Panama City Tocumen Intl

Mon 9/2

8:16-16:10

2 stops24h 54m

R31 364

Flights are sorted by cheapest return flights first.

Deals found on 18/12

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 925). Flying from South Africa to Panama in September is currently the most expensive (average of R21 178). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ZA to PA?

Find hourly flight availability from South Africa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 20 December 2025.

Unlike at midday, when flights are generally more expensive, you can save up to 21% on flights from South Africa to Panama by exploring options for tickets in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 20 December 2025.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 428 reviews
Check prices

Boarding

7,8

Comfort

7,6

Food

7,2

Overall

7,7

Crew

8,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
KLM
7,7
Good
1 428 reviews
KLM
7,7
Good
1 428 reviews
Check prices

Boarding

7,8

Comfort

7,6

Food

7,2

Overall

7,7

Crew

8,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
Air France
7,4
Good
1 509 reviews
KLM
7,7
Good
1 428 reviews
Check prices

Boarding

7,8

Comfort

7,6

Food

7,2

Overall

7,7

Crew

8,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
United Airlines
7,4
Good
9 097 reviews
KLM
7,7
Good
1 428 reviews
Check prices

Boarding

7,8

Comfort

7,6

Food

7,2

Overall

7,7

Crew

8,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
British Airways
6,7
Okay
7 595 reviews
KLM
7,7
Good
1 428 reviews
Check prices

Boarding

7,8

Comfort

7,6

Food

7,2

Overall

7,7

Crew

8,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R20 022, United Airlines can have you in Panama from South Africa in 26h 08m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 925). Flying from South Africa to Panama in September is currently the most expensive (average of R21 178). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
OR Tambo to San José flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to Liberia flights
Cape Town to Guatemala City flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 20 December 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR17 638AverageR21 591FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR18 627AverageR21 903FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapestR22 584AverageR25 931FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 320AverageR26 013FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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