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Cheap flights from South Africa to Panama from R18 468

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/6. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Jul 3 — Jul 101
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 June 2026.

Thu 15/1019:50
CPT
-
PTY
1 stop30h 41m
United Airlines
Sat 31/107:55
PTY
-
CPT
2 stops51h 05m
United Airlines
Deal found 31/5R20 417
Wed 23/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Wed 30/915:30
PTY
-
JNB
2 stops44h 00m
United Airlines
Deal found 30/5R22 593
Mon 15/65:45
JNB
-
PTY
3 stops25h 50m
Multiple Airlines
Thu 18/618:31
PTY
-
JNB
2 stops31h 04m
Multiple Airlines
Deal found 1/6R23 162
Wed 14/1022:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Wed 21/109:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Deal found 3/6R24 266
Fri 10/715:00
JNB
-
PTY
2 stops22h 23m
Multiple Airlines
Fri 17/722:12
PTY
-
JNB
2 stops30h 58m
Multiple Airlines
Deal found 1/6R25 160
Sun 14/615:05
JNB
-
PTY
2 stops36h 30m
United Airlines
Mon 29/69:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Deal found 31/5R26 037
Tue 14/722:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Tue 28/79:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Deal found 30/5R26 491
Wed 23/921:15
JNB
-
PTY
2 stops53h 20m
British Airways
Wed 30/921:05
PTY
-
JNB
2 stops29h 20m
British Airways
Deal found 30/5R26 784
Thu 15/1016:35
CPT
-
PTY
1 stop34h 50m
Turkish Airlines
Sat 31/1022:00
PTY
-
CPT
1 stop31h 05m
Turkish Airlines
Deal found 31/5R28 879
Thu 15/1016:35
CPT
-
PTY
3 stops33h 05m
Multiple Airlines
Sat 31/1018:32
PTY
-
CPT
2 stops33h 03m
Multiple Airlines
Deal found 31/5R32 339

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 3 June 2026.

Round-trip from

R20 417

One-way from

R18 468

Popular in

December

Cheapest in

April

Average price

R24 640
United Airlines
  • United Airlines
  • 15/10-31/10
  • 3 total stops
  • 81h 46m total
  • South Africa to Panama
Search Deals
15/6
  • 15/6
  • 3 total stops
  • 43h 45m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (R6 612 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R6 739 potential savings vs. average return price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 3 June 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 15/10

19:50-19:31

1 stop30h 41m

Panama City Tocumen Intl

Sat 31/10

7:55-18:00

2 stops51h 05m

R20 417

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 23/9

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Wed 30/9

15:30-18:30

2 stops44h 00m

R22 593
Fastest return journey

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 14/10

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Wed 21/10

9:45-18:30

1 stop25h 45m

R24 266

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 14/7

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Tue 28/7

9:45-18:30

1 stop25h 45m

R26 491

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 23/9

21:15-19:35

2 stops53h 20m

Panama City Tocumen Intl

Wed 30/9

21:05-9:25

2 stops29h 20m

R26 784

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 14/6

19:00-6:13

2 stops42h 13m

Panama City Tocumen Intl

Mon 29/6

9:45-18:30

1 stop25h 45m

R26 800

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 15/10

16:35-20:25

1 stop34h 50m

Panama City Tocumen Intl

Sat 31/10

22:00-12:05

1 stop31h 05m

R28 879

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 15/10

16:35-18:40

3 stops33h 05m

Panama City Tocumen Intl

Sat 31/10

18:32-10:35

2 stops33h 03m

R32 339
Cheapest one-way

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 15/6

19:30-19:35

2 stops55h 05m

R18 695
Fastest single journey

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Mon 15/6

19:50-19:31

1 stop30h 41m

R22 609

Flights are sorted by cheapest return flights first.

Deals found on 3/6

Sorted by cheapest first

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 903). Flying from South Africa to Panama in September is currently the most expensive (average of R18 906). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 3 June 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 524 reviews
Check prices

Overall

7,8

Comfort

7,7

Crew

8,4

Boarding

7,8

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7,8
Good
1 524 reviews
KLM
7,8
Good
1 524 reviews
Check prices

Overall

7,8

Comfort

7,7

Crew

8,4

Boarding

7,8

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air France
7,4
Good
1 595 reviews
KLM
7,8
Good
1 524 reviews
Check prices

Overall

7,8

Comfort

7,7

Crew

8,4

Boarding

7,8

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
United Airlines
7,4
Good
9 775 reviews
KLM
7,8
Good
1 524 reviews
Check prices

Overall

7,8

Comfort

7,7

Crew

8,4

Boarding

7,8

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
British Airways
6,7
Okay
8 026 reviews
KLM
7,8
Good
1 524 reviews
Check prices

Overall

7,8

Comfort

7,7

Crew

8,4

Boarding

7,8

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R20 417, United Airlines can have you in Panama from South Africa in 30h 41m. Airlines will cover a distance of 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 903). Flying from South Africa to Panama in September is currently the most expensive (average of R18 906). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Guatemala City flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to Liberia flights
OR Tambo to San José flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 3 June 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 602AverageR21 074FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR18 690AverageR22 154FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapestR23 547AverageR24 825FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR24 550AverageR26 373FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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