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Cheap flights from South Africa to Panama from R18 730

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/8. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Aug 11 — Aug 181
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 July 2026.

Thu 24/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Fri 2/1022:29
PTY
-
JNB
2 stops37h 01m
United Airlines
Deal found 7/7R20 144
Fri 25/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Sun 4/108:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Deal found 7/7R20 567
Sun 23/820:00
CPT
-
PTY
1 stop31h 35m
United Airlines
Sun 30/89:45
PTY
-
CPT
2 stops43h 55m
United Airlines
Deal found 10/7R20 713
Mon 24/822:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Mon 31/812:56
PTY
-
JNB
2 stops70h 34m
United Airlines
Deal found 10/7R22 306
Wed 23/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Sun 4/109:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Deal found 7/7R22 339
Mon 2/1119:35
JNB
-
PTY
2 stops52h 30m
British Airways
Fri 13/1118:35
PTY
-
JNB
2 stops56h 50m
British Airways
Deal found 8/7R24 891
Mon 24/89:50
JNB
-
PTY
1 stop29h 21m
Multiple Airlines
Mon 31/821:41
PTY
-
JNB
2 stops30h 19m
Multiple Airlines
Deal found 10/7R26 030
Sat 18/722:00
JNB
-
PTY
2 stops27h 37m
United Airlines
Sat 1/818:06
PTY
-
JNB
2 stops41h 24m
United Airlines
Deal found 7/7R26 241
Sun 9/815:05
JNB
-
PTY
2 stops36h 30m
United Airlines
Sun 30/88:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Deal found 11/7R26 371
Sun 23/823:15
CPT
-
PTY
1 stop24h 35m
KLM
Sun 30/818:50
PTY
-
CPT
1 stop43h 35m
KLM
Deal found 10/7R27 542
Wed 9/127:55
CPT
-
PTY
1 stop43h 25m
Air France
Wed 23/127:55
PTY
-
CPT
2 stops38h 55m
Air France
Deal found 9/7R27 899
Wed 9/127:55
CPT
-
PTY
2 stops39h 35m
Multiple Airlines
Wed 23/127:55
PTY
-
CPT
2 stops38h 55m
Multiple Airlines
Deal found 9/7R28 013

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 12 July 2026.

Round-trip from

R20 713

One-way from

R18 730

Popular in

December

Cheapest in

April

Average price

R20 112
United Airlines
  • United Airlines
  • 23/8-30/8
  • 3 total stops
  • 75h 30m total
  • South Africa to Panama
Search Deals
24/8
  • 24/8
  • 2 total stops
  • 32h 10m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (R10 433 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (R8 573 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 12 July 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 23/9

22:00-14:14

2 stops47h 14m

Panama City Tocumen Intl

Sat 3/10

9:45-18:30

1 stop25h 45m

R20 144

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 25/9

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Sat 3/10

22:29-18:30

2 stops37h 01m

R20 567

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 25/9

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Sun 4/10

8:11-18:30

2 stops27h 19m

R20 567

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 23/8

20:00-20:35

1 stop31h 35m

Panama City Tocumen Intl

Sun 30/8

9:45-12:40

2 stops43h 55m

R20 713

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 23/9

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Sun 4/10

8:11-18:30

2 stops27h 19m

R22 339

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 24/8

9:50-8:11

1 stop29h 21m

Panama City Tocumen Intl

Mon 31/8

21:41-11:00

2 stops30h 19m

R26 030

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 9/8

15:05-20:35

2 stops36h 30m

Panama City Tocumen Intl

Sun 30/8

8:11-18:30

2 stops27h 19m

R26 371

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 23/8

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Sun 30/8

18:50-21:25

1 stop43h 35m

R27 542

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 9/12

7:55-16:30

2 stops39h 35m

Panama City Tocumen Intl

Wed 23/12

7:55-5:50

2 stops38h 55m

R28 013

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 24/8

22:00-19:31

1 stop28h 31m

Panama City Tocumen Intl

Mon 31/8

22:55-18:30

1 stop36h 35m

R30 013

Flights are sorted by cheapest return flights first.

Deals found on 10/7

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 910). Flying from South Africa to Panama in September is currently the most expensive (average of R18 925). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 12 July 2026.
Check out reviews from past customers who have flown with KLM,Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 537 reviews
Check prices

Food

7,3

Crew

8,4

Boarding

7,8

Overall

7,8

Entertainment

7,2

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,8
Good
1 537 reviews
KLM
7,8
Good
1 537 reviews
Check prices

Food

7,3

Crew

8,4

Boarding

7,8

Overall

7,8

Entertainment

7,2

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,5
Good
1 623 reviews
KLM
7,8
Good
1 537 reviews
Check prices

Food

7,3

Crew

8,4

Boarding

7,8

Overall

7,8

Entertainment

7,2

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 981 reviews
KLM
7,8
Good
1 537 reviews
Check prices

Food

7,3

Crew

8,4

Boarding

7,8

Overall

7,8

Entertainment

7,2

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6,7
Okay
8 102 reviews
KLM
7,8
Good
1 537 reviews
Check prices

Food

7,3

Crew

8,4

Boarding

7,8

Overall

7,8

Entertainment

7,2

Comfort

7,7

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R27 542, United Airlines can have you in Panama from South Africa in 24h 35m. Airlines will cover a distance of 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R6 910). Flying from South Africa to Panama in September is currently the most expensive (average of R18 925). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to San José flights
OR Tambo to Liberia flights
Cape Town to Guatemala City flights
Cape Town to Panama City flights
OR Tambo to San José flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 12 July 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR18 708AverageR22 381FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR18 787AverageR20 338FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Air FranceCheapestR23 570AverageR24 285FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR24 574AverageR26 399FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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