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Cheap flights from South Africa to Panama from R8 999

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/3. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Apr 1 — Apr 81
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 March 2026.

Sat 7/322:00
JNB
-
PTY
2 stops29h 27m
United Airlines
Sat 14/319:20
PTY
-
JNB
2 stops40h 15m
United Airlines
Deal found 27/2R18 603
Sun 18/1020:00
CPT
-
PTY
1 stop41h 13m
United Airlines
Tue 10/118:55
PTY
-
CPT
2 stops26h 05m
United Airlines
Deal found 26/2R18 651
Mon 19/1019:50
CPT
-
PTY
2 stops49h 24m
United Airlines
Thu 12/1116:41
PTY
-
CPT
2 stops64h 29m
United Airlines
Deal found 26/2R18 730
Mon 19/1015:50
CPT
-
PTY
1 stop23h 21m
Multiple Airlines
Sat 14/1119:06
PTY
-
CPT
1 stop32h 49m
Multiple Airlines
Deal found 26/2R18 794
Fri 5/619:25
JNB
-
PTY
2 stops55h 35m
British Airways
Sun 21/621:05
PTY
-
JNB
2 stops53h 20m
British Airways
Deal found 1/3R19 511
Sun 18/1020:00
CPT
-
PTY
1 stop41h 13m
United Airlines
Thu 12/119:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Deal found 26/2R20 801
Thu 15/1019:50
CPT
-
PTY
2 stops25h 32m
United Airlines
Sun 15/1116:41
PTY
-
CPT
2 stops40h 29m
United Airlines
Deal found 26/2R20 896
Wed 21/1017:55
CPT
-
PTY
2 stops50h 38m
United Airlines
Tue 17/118:55
PTY
-
CPT
2 stops26h 05m
United Airlines
Deal found 26/2R21 151
Sun 12/414:50
JNB
-
PTY
2 stops30h 25m
Multiple Airlines
Sat 18/43:05
PTY
-
JNB
2 stops25h 50m
Multiple Airlines
Deal found 26/2R22 537
Sat 17/1019:50
CPT
-
PTY
2 stops31h 51m
United Airlines
Thu 12/1116:41
PTY
-
CPT
2 stops64h 29m
United Airlines
Deal found 26/2R22 648
Tue 20/1020:00
CPT
-
PTY
1 stop31h 35m
United Airlines
Thu 12/119:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Deal found 26/2R22 951
Tue 20/1020:00
CPT
-
PTY
1 stop31h 35m
United Airlines
Sat 21/119:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Deal found 26/2R23 062

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 2 March 2026.

Round-trip from

R19 511

One-way from

R8 999

Popular in

December

Cheapest in

February

Average price

R20 944
British Airways
  • British Airways
  • 5/6-21/6
  • 4 total stops
  • 108h 55m total
  • South Africa to Panama
Search Deals
31/3
  • 31/3
  • 3 total stops
  • 52h 35m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (R15 242 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R4 874 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 2 March 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 12/4

14:50-14:15

2 stops30h 25m

Panama City Tocumen Intl

Sat 18/4

3:05-11:55

2 stops25h 50m

R22 537

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 29/3

22:20-6:39

3 stops39h 19m

Panama City Tocumen Intl

Sun 5/4

18:31-8:35

2 stops31h 04m

R23 190

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 28/3

16:40-7:54

2 stops46h 14m

Panama City Tocumen Intl

Sat 4/4

15:12-11:55

1 stop37h 43m

R24 353

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 12/4

18:00-16:50

2 stops29h 50m

Panama City Tocumen Intl

Sun 19/4

18:50-21:20

1 stop43h 30m

R24 830

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 21/5

17:50-18:25

2 stops31h 35m

Panama City Tocumen Intl

Mon 25/5

22:20-10:30

1 stop29h 10m

R28 095

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 22/5

16:35-20:25

1 stop34h 50m

Panama City Tocumen Intl

Tue 26/5

20:05-11:50

1 stop32h 45m

R29 226

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Fri 27/3

19:45-14:14

2 stops49h 29m

Panama City Tocumen Intl

Sun 26/4

8:11-18:30

2 stops27h 19m

R29 816

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Fri 22/5

20:00-20:27

3 stops31h 27m

Panama City Tocumen Intl

Tue 26/5

15:30-17:10

2 stops42h 40m

R29 847

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 21/5

19:50-16:12

2 stops27h 22m

Panama City Tocumen Intl

Mon 25/5

9:13-15:20

1 stop23h 07m

R29 911

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sun 12/4

22:20-6:44

2 stops63h 24m

Panama City Tocumen Intl

Sun 19/4

22:45-5:30

2 stops71h 45m

R31 138

Flights are sorted by cheapest return flights first.

Deals found on 1/3

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 565). Flying from South Africa to Panama in September is currently the most expensive (average of R20 116). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 2 March 2026.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 461 reviews
Check prices

Crew

8,4

Overall

7,7

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Food

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7,7
Good
1 461 reviews
KLM
7,7
Good
1 461 reviews
Check prices

Crew

8,4

Overall

7,7

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Food

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air France
7,4
Good
1 541 reviews
KLM
7,7
Good
1 461 reviews
Check prices

Crew

8,4

Overall

7,7

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Food

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7,4
Good
9 371 reviews
KLM
7,7
Good
1 461 reviews
Check prices

Crew

8,4

Overall

7,7

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Food

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6,7
Okay
7 774 reviews
KLM
7,7
Good
1 461 reviews
Check prices

Crew

8,4

Overall

7,7

Entertainment

7,1

Comfort

7,6

Boarding

7,8

Food

7,3

Reviews

1 / 20
2,0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R24 830, KLM can have you in Panama from South Africa in 29h 50m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 565). Flying from South Africa to Panama in September is currently the most expensive (average of R20 116). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to San José flights
OR Tambo to Panama City flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to Liberia flights
Cape Town to Guatemala City flights

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 2 March 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapestR17 707AverageR20 173FlexibilityNo cancel feeOn-time70%
Search British Airways flights
United AirlinesCheapestR18 241AverageR20 693FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
KLMCheapestR22 067AverageR25 024FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 090AverageR24 242FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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