Cheap flights from South Africa to Panama from R19 504

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Dec 31 — Jan 71
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 1 December 2025.

Round-trip from

R24 038

Popular in

December

Cheapest in

January

Average price

R27 853
United Airlines
  • United Airlines
  • 14/1-21/1
  • 4 total stops
  • 56h 15m total
  • South Africa to Panama
High demand for flights, 0% potential price rise
Cheapest flight prices on average. 1% potential price decrease (R5 257 potential savings vs. average return price).
Average for round-trip flights in December 2025

Find flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1 December 2025.

Mon 15/1213:45JNB - PTY
2 stops32h 57mQatar Airways
Tue 6/114:27PTY - JNB
2 stops35h 13mQatar Airways
Deal found 28/11R44 278
Mon 15/1223:59JNB - PTY
2 stops27h 11mKLM
Tue 6/118:45PTY - JNB
1 stop44h 20mKLM
Deal found 30/11R45 886
Mon 15/1219:20JNB - PTY
1 stop31h 50mMultiple Airlines
Tue 6/118:45PTY - JNB
1 stop44h 20mMultiple Airlines
Deal found 30/11R46 759

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 1 December 2025.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 11/5

9:50-0:45

2 stops21h 55m

Panama City Tocumen Intl

Sun 24/5

3:20-7:05

2 stops20h 45m

R19 504

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Wed 14/1

20:50-20:35

2 stops30h 45m

Panama City Tocumen Intl

Wed 21/1

9:30-18:00

2 stops25h 30m

R24 038

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 5/2

15:20-20:10

2 stops35h 50m

Panama City Tocumen Intl

Mon 9/2

22:20-5:50

1 stop24h 30m

R25 698

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 15/1

22:00-15:52

2 stops48h 52m

Panama City Tocumen Intl

Thu 22/1

16:50-10:25

2 stops34h 35m

R26 160

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 11/5

22:00-18:37

2 stops27h 37m

Panama City Tocumen Intl

Mon 25/5

7:55-18:30

2 stops27h 35m

R26 331

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 11/5

23:15-16:50

1 stop24h 35m

Panama City Tocumen Intl

Mon 25/5

18:50-21:20

1 stop43h 30m

R26 621

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 5/2

14:00-16:30

2 stops33h 30m

Panama City Tocumen Intl

Mon 9/2

22:20-21:55

2 stops64h 35m

R26 827

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 12/3

19:35-12:40

2 stops48h 05m

Panama City Tocumen Intl

Mon 16/3

15:13-10:25

2 stops36h 12m

R27 015

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Tue 13/1

0:30-0:40

3 stops31h 10m

Panama City Tocumen Intl

Tue 20/1

2:55-14:00

3 stops28h 05m

R27 460

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 12/3

23:59-16:30

1 stop23h 31m

Panama City Tocumen Intl

Mon 16/3

18:45-22:05

1 stop44h 20m

R27 648

Flights are sorted by cheapest return flights first.

Deals found on 29/11

Showing 1-10 of 11 results
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R8 093). Flying from South Africa to Panama in September is currently the most expensive (average of R21 626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ZA to PA?

Find hourly flight availability from South Africa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 1 December 2025.

Unlike at midday, when flights are generally more expensive, you can save up to 23% on flights from South Africa to Panama by exploring options for tickets in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 1 December 2025.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7,6

Food

7,2

Crew

8,4

Boarding

7,8

Entertainment

7,1

Overall

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7,6

Food

7,2

Crew

8,4

Boarding

7,8

Entertainment

7,1

Overall

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7,6

Food

7,2

Crew

8,4

Boarding

7,8

Entertainment

7,1

Overall

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7,6

Food

7,2

Crew

8,4

Boarding

7,8

Entertainment

7,1

Overall

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7,6

Food

7,2

Crew

8,4

Boarding

7,8

Entertainment

7,1

Overall

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Comfort

7,6

Food

7,2

Crew

8,4

Boarding

7,8

Entertainment

7,1

Overall

7,7

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Africa to Panama?

    For as low as R24 038, United Airlines can have you in Panama from South Africa in 30h 45m. Airlines will cover a distance of 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R8 093). Flying from South Africa to Panama in September is currently the most expensive (average of R21 626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from South Africa to Panama

Discover the top 4 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 1 December 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 011AverageR22 044FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR19 021AverageR22 407FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapestR23 061AverageR26 211FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR23 813AverageR26 640FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

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How does Cheapflights help users find flights from South Africa to Panama?

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Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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