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Cheap flights from South Africa to Panama from R19 936

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/11. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Dec 26 — Jan 21
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 26 November 2025.

Round-trip from

R25 540

Popular in

December

Cheapest in

January

Average price

R25 592
Air France
  • Air France
  • 5/2-9/2
  • 3 total stops
  • 60h 20m total
  • South Africa to Panama
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease (R5 314 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
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Find flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 November 2025.

Thu 27/1120:50CPT - PTY
2 stops30h 45mUnited Airlines
Thu 4/128:16PTY - CPT
2 stops24h 54mUnited Airlines
Deal found 26/11R19 936
Sat 29/1115:05JNB - PTY
2 stops29h 50mUnited Airlines
Sun 7/129:30PTY - JNB
2 stops26h 05mUnited Airlines
Deal found 25/11R28 179
Thu 27/1114:25CPT - PTY
3 stops30h 47mMultiple Airlines
Thu 4/1222:25PTY - CPT
3 stops32h 35mMultiple Airlines
Deal found 26/11R40 423
Sat 29/117:10JNB - PTY
2 stops30h 19mMultiple Airlines
Sun 7/1221:33PTY - JNB
1 stop27h 12mMultiple Airlines
Deal found 25/11R42 458
Sat 29/1123:59JNB - PTY
1 stop23h 31mKLM
Sun 7/1218:45PTY - JNB
1 stop44h 20mKLM
Deal found 25/11R44 631
Mon 15/1213:45JNB - PTY
2 stops32h 57mQatar Airways
Tue 6/116:31PTY - JNB
2 stops33h 09mQatar Airways
Deal found 25/11R46 028
Mon 15/1213:45JNB - PTY
2 stops32h 57mMultiple Airlines
Tue 6/116:31PTY - JNB
2 stops40h 04mMultiple Airlines
Deal found 24/11R48 253
Mon 15/1223:59JNB - PTY
1 stop23h 31mKLM
Tue 6/118:45PTY - JNB
1 stop44h 20mKLM
Deal found 25/11R49 184

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 26 November 2025.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

South Africa

Fly to

Panama

Route

Depart

Return

Price

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Thu 5/2

15:20-20:10

2 stops35h 50m

Panama City Tocumen Intl

Mon 9/2

22:20-5:50

1 stop24h 30m

R25 540

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 12/3

22:00-14:22

2 stops47h 22m

Panama City Tocumen Intl

Mon 16/3

15:13-7:35

2 stops33h 22m

R26 937

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 12/3

19:20-20:10

1 stop31h 50m

Panama City Tocumen Intl

Mon 16/3

22:20-12:10

1 stop30h 50m

R27 524

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 12/3

23:59-16:30

1 stop23h 31m

Panama City Tocumen Intl

Mon 16/3

18:45-22:05

1 stop44h 20m

R27 851

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 10/1

16:40-1:00

3 stops39h 20m

Panama City Tocumen Intl

Fri 16/1

2:55-12:40

2 stops26h 45m

R38 302

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 10/1

22:00-19:38

2 stops28h 38m

Panama City Tocumen Intl

Sat 17/1

9:30-18:35

2 stops26h 05m

R39 802

Flights are sorted by cheapest return flights first.

Deals found on 23/11

Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R8 157). Flying from South Africa to Panama in September is currently the most expensive (average of R21 798). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ZA to PA?

Find hourly flight availability from South Africa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 26 November 2025.

Unlike at midday, when flights are generally more expensive, you can save up to 23% on flights from South Africa to Panama by exploring options for tickets in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 26 November 2025.
Check out reviews from past customers who have flown with KLM, Air France, andUnited Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,7
Good
1 423 reviews
Check prices

Overall

7,7

Entertainment

7,1

Food

7,2

Boarding

7,8

Crew

8,4

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7,7
Good
1 423 reviews
KLM
7,7
Good
1 423 reviews
Check prices

Overall

7,7

Entertainment

7,1

Food

7,2

Boarding

7,8

Crew

8,4

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7,4
Good
1 498 reviews
KLM
7,7
Good
1 423 reviews
Check prices

Overall

7,7

Entertainment

7,1

Food

7,2

Boarding

7,8

Crew

8,4

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7,4
Good
9 046 reviews
KLM
7,7
Good
1 423 reviews
Check prices

Overall

7,7

Entertainment

7,1

Food

7,2

Boarding

7,8

Crew

8,4

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Turkish Airlines
7,3
Good
4 060 reviews
KLM
7,7
Good
1 423 reviews
Check prices

Overall

7,7

Entertainment

7,1

Food

7,2

Boarding

7,8

Crew

8,4

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6,7
Okay
7 539 reviews
KLM
7,7
Good
1 423 reviews
Check prices

Overall

7,7

Entertainment

7,1

Food

7,2

Boarding

7,8

Crew

8,4

Comfort

7,6

Reviews

1 / 20
2,0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R27 851, Air France can have you in Panama from South Africa in 23h 31m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, August is the cheapest month in which you can book a flight from South Africa to Panama (average of R8 157). Flying from South Africa to Panama in September is currently the most expensive (average of R21 798). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Panama City flights
Cape Town to Guatemala City flights
Cape Town to San José flights
OR Tambo to San José flights
OR Tambo to Liberia flights

Top 5 airlines flying from South Africa to Panama

Discover the top 5 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 26 November 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR18 155AverageR22 271FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR19 173AverageR22 586FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapestR23 245AverageR26 420FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapestR24 003AverageR26 853FlexibilityNo cancel feeOn-time77%
Search Air France flights
Turkish AirlinesCheapestR36 296AverageR37 984FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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