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Cheap flights from South Africa to Panama from R14 029

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/5. Fares are subject to change and may not be available on all flights or dates of travel.
JNB — PTY
Jun 17 — Jun 241
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama
Explore the most affordable flight options available from South Africa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 May 2026.

Thu 5/1119:35
JNB
-
PTY
2 stops32h 30m
British Airways
Wed 18/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R19 267
Wed 11/1119:35
JNB
-
PTY
2 stops56h 30m
British Airways
Tue 17/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R19 451
Thu 11/614:50
JNB
-
PTY
1 stop26h 08m
Multiple Airlines
Wed 17/612:00
PTY
-
JNB
1 stop16h 55m
Multiple Airlines
Deal found 13/5R20 201
Thu 5/1119:35
JNB
-
PTY
2 stops32h 30m
British Airways
Thu 19/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R20 302
Wed 11/1119:35
JNB
-
PTY
2 stops56h 30m
British Airways
Fri 20/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R20 485
Tue 10/1119:35
JNB
-
PTY
2 stops32h 30m
British Airways
Tue 17/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R21 286
Thu 5/1119:35
JNB
-
PTY
2 stops32h 30m
British Airways
Sat 21/1114:43
PTY
-
JNB
2 stops60h 42m
British Airways
Deal found 15/5R21 419
Mon 9/1119:35
JNB
-
PTY
2 stops56h 30m
British Airways
Sun 15/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R21 469
Thu 5/1110:25
JNB
-
PTY
2 stops40h 37m
United Airlines
Wed 18/1110:00
PTY
-
JNB
1 stop25h 35m
United Airlines
Deal found 15/5R21 486
Wed 11/1119:35
JNB
-
PTY
2 stops56h 30m
British Airways
Sat 21/1114:43
PTY
-
JNB
2 stops60h 42m
British Airways
Deal found 15/5R21 603
Sat 7/1119:35
JNB
-
PTY
2 stops32h 30m
British Airways
Tue 17/1114:43
PTY
-
JNB
2 stops36h 42m
British Airways
Deal found 15/5R21 770
Tue 10/1119:35
JNB
-
PTY
2 stops32h 30m
British Airways
Wed 18/1122:35
PTY
-
JNB
2 stops28h 50m
British Airways
Deal found 15/5R21 903

Find flight deals from South Africa to Panama

Keep the following information in mind while searching for South Africa to Panama flight deals. Data was last updated 18 May 2026.

Round-trip from

R19 267

One-way from

R14 029

Popular in

December

Cheapest in

April

Average price

R20 819
British Airways
  • British Airways
  • 5/11-15/11
  • 4 total stops
  • 69h 12m total
  • South Africa to Panama
Search Deals
25/5
  • 25/5
  • 3 total stops
  • 51h 55m total
  • South Africa to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (R7 716 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (R7 164 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Africa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 18 May 2026.
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 5/11

15:05-20:02

2 stops35h 57m

Panama City Tocumen Intl

Sun 15/11

10:00-18:35

1 stop25h 35m

R21 486

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 9/11

10:25-20:02

2 stops40h 37m

Panama City Tocumen Intl

Wed 18/11

10:00-18:35

1 stop25h 35m

R21 486

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Wed 11/11

19:35-21:05

2 stops56h 30m

Panama City Tocumen Intl

Sat 21/11

14:43-10:25

2 stops60h 42m

R21 603

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 9/11

19:35-21:05

2 stops56h 30m

Panama City Tocumen Intl

Thu 19/11

14:43-10:25

2 stops60h 42m

R22 520

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Sat 7/11

19:35-21:05

2 stops32h 30m

Panama City Tocumen Intl

Fri 20/11

14:43-10:25

2 stops36h 42m

R22 804

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Tue 10/11

10:25-13:31

2 stops34h 06m

Panama City Tocumen Intl

Wed 18/11

10:00-18:35

1 stop25h 35m

R23 321

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Thu 11/6

14:50-14:15

2 stops30h 25m

Panama City Tocumen Intl

Wed 17/6

4:25-11:55

2 stops24h 30m

R23 471

JohannesburgPanama City

JNB - PTY

JNBPTY

Johannesburg OR Tambo

Mon 22/6

10:25-19:31

2 stops40h 06m

Panama City Tocumen Intl

Fri 3/7

9:45-18:30

1 stop25h 45m

R24 739

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 5/7

20:00-19:31

2 stops30h 31m

Panama City Tocumen Intl

Sun 12/7

22:55-15:20

2 stops33h 25m

R28 309

Cape TownPanama City

CPT - PTY

CPTPTY

Cape Town Intl

Sun 5/7

20:00-14:14

2 stops49h 14m

Panama City Tocumen Intl

Fri 17/7

9:45-17:10

1 stop24h 25m

R30 527

Flights are sorted by cheapest return flights first.

Deals found on 18/5

Showing 1-10 of 23 resultsSorted by cheapest first
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 090). Flying from South Africa to Panama in September is currently the most expensive (average of R19 417). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 18 May 2026.
Check out reviews from past customers who have flown with KLM,Air France, andLATAM Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7,8
Good
1 517 reviews
Check prices

Crew

8,4

Boarding

7,8

Overall

7,8

Comfort

7,7

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7,8
Good
1 517 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Crew

8,4

Boarding

7,8

Overall

7,8

Comfort

7,7

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air France
7,4
Good
1 588 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Crew

8,4

Boarding

7,8

Overall

7,8

Comfort

7,7

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
LATAM Airlines
7,4
Good
1 924 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Crew

8,4

Boarding

7,8

Overall

7,8

Comfort

7,7

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
United Airlines
7,4
Good
9 737 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Crew

8,4

Boarding

7,8

Overall

7,8

Comfort

7,7

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
British Airways
6,7
Okay
7 987 reviews
KLM
7,8
Good
1 517 reviews
Check prices

Crew

8,4

Boarding

7,8

Overall

7,8

Comfort

7,7

Entertainment

7,2

Food

7,3

Reviews

1 / 20
6,0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from South Africa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Africa to Panama?

    For as low as R21 486, United Airlines can have you in Panama from South Africa in 40h 37m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, May is the cheapest month in which you can book a flight from South Africa to Panama (average of R7 090). Flying from South Africa to Panama in September is currently the most expensive (average of R19 417). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Africa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
OR Tambo to Panama City flights
Cape Town to Panama City flights
Cape Town to San José flights
OR Tambo to San José flights
Cape Town to Guatemala City flights
OR Tambo to Liberia flights

Top 5 airlines flying from South Africa to Panama

Discover the top 5 airlines that operate flights from South Africa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 18 May 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapestR8 019AverageR14 832FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights
United AirlinesCheapestR19 161AverageR21 191FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapestR19 196AverageR21 583FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapestR24 184AverageR25 497FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapestR25 076AverageR26 857FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Africa to Panama?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama from South Africa today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from South Africa to Panama?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from South Africa to Panama.

Can Cheapflights find flights from South Africa to Panama with no change fees?

Need flexible booking options for your flight to Panama from South Africa? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from South Africa to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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