Cheap flights from South Africa to Panama from R12 510

JNB — PTY
Dec 11 — Dec 181
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Africa to Panama

Enter your travel dates to find the best prices.

Cheapest flights from South Africa to Panama

Sun 15/1120:50 -
1 stop23h 41m
Sun 22/1112:04 -
2 stops45h 06m
Deal found 9/11R20 565
Wed 11/1115:05 -
2 stops35h 57m
Tue 26/119:28 -
2 stops40h 07m
Deal found 7/11R21 206
Tue 8/1219:45 -
2 stops55h 56m
Wed 30/1223:55 -
1 stop35h 40m
Deal found 9/11R22 719
Thu 24/1219:55 -
1 stop30h 50m
Thu 31/1221:30 -
1 stop30h 10m
Deal found 9/11R24 396
Wed 11/1115:35 -
1 stop22h 04m
Mon 16/1112:02 -
1 stop17h 43m
Deal found 8/11R24 922
Mon 21/1222:00 -
2 stops29h 27m
Thu 14/110:00 -
1 stop25h 35m
Deal found 8/11R25 070
Fri 25/1220:50 -
2 stops29h 48m
Fri 1/18:55 -
2 stops48h 15m
Deal found 10/11R26 812
Tue 8/1220:50 -
1 stop30h 45m
Sat 26/1210:00 -
2 stops38h 40m
Deal found 9/11R26 878
Fri 11/1220:50 -
1 stop23h 41m
Sat 26/1210:00 -
2 stops38h 40m
Deal found 9/11R29 097
Thu 10/1220:50 -
2 stops40h 47m
Sat 26/1223:55 -
1 stop35h 05m
Deal found 9/11R31 234
Sun 13/1220:50 -
1 stop23h 41m
Sat 26/1223:55 -
1 stop35h 05m
Deal found 9/11R33 371
Thu 24/120:30 -
1 stop26h 25m
Fri 1/122:30 -
1 stop24h 55m
Deal found 10/11R35 163

Find flight deals from South Africa to Panama

Round-trip from

R20 647

One-way from

R12 510

Popular in

August

Cheapest in

November

Average price

R10 735
United Airlines
  • United Airlines
  • 18/3-27/3
  • 3 total stops
  • 83h 10m total
  • South Africa to Panama
6/2-31/12
  • 6/2-31/12
  • 3 total stops
  • 41h 15m total
  • South Africa to Panama
Highest demand for flights based on searches. 5% potential increase in price (R20 461 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (R7 683 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from South Africa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Sat 6/2

15:05-1:20

3 stops41h 15m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R12 510

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Mon 21/12

8:55-15:15

3 stops37h 20m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R13 990

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Fri 25/12

23:10-1:20

3 stops57h 10m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R14 729

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 19/1

19:55-17:15

2 stops28h 20m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R15 486

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Tue 19/1

19:55-19:45

1 stop30h 50m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R16 472

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Sat 19/12

19:55-19:45

1 stop30h 50m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R16 653

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Thu 17/12

19:55-19:45

1 stop30h 50m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R16 965

JohannesburgPanama City

JNB Johannesburg OR Tambo - PTY Panama City Tocumen Intl

JNBPTY

Johannesburg OR Tambo

Thu 17/12

6:05-9:35

2 stops34h 30m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R17 573

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Sun 7/2

20:00-6:40

2 stops41h 40m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R18 593

Cape TownPanama City

CPT Cape Town Intl - PTY Panama City Tocumen Intl

CPTPTY

Cape Town Intl

Sun 7/2

17:15-20:05

1 stop33h 50m

Panama City Tocumen Intl

Wed 31/12

0:00-7:00

Nonstop0h 00m

R18 757

Flights are sorted by cheapest return flights first.

Deals found on 9/11

Showing 1-10 of 26 resultsSorted by cheapest first
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Best time to book a flight from South Africa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Africa with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from South Africa to Panama

What is the cheapest month to book a flight from South Africa to Panama?

Currently, November is the cheapest month in which you can book a flight from South Africa to Panama (average of R10 735). Flying from South Africa to Panama in August is currently the most expensive (average of R26 533). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Check out reviews from past customers who have flown with United Airlines from South Africa to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8,1

Overall

7,3

Food

6,7

Entertainment

7,1

Boarding

7,7

Comfort

7,3

Reviews

1 / 20
4,0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Crew

8,1

Overall

7,3

Food

6,7

Entertainment

7,1

Boarding

7,7

Comfort

7,3

Reviews

1 / 20
4,0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

  • How long is the flight from South Africa to Panama?

    For as low as R22 653, United Airlines can have you in Panama from South Africa in 26h 55m. Airlines will cover a distance of 12194 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from South Africa to Panama that include hotel bookings?

    Yes. In addition to deals on South Africa to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Africa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Africa to Panama.

  • Can I find deals for business class flights from South Africa to Panama?

    Yes. Cheapflights offers flight deals from South Africa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Africa to Panama?

    Currently, November is the cheapest month in which you can book a flight from South Africa to Panama (average of R10 735). Flying from South Africa to Panama in August is currently the most expensive (average of R26 533). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Africa to Panama

Top airline flying from South Africa to Panama

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR19 051AverageR21 083FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

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