Cheap flights from Panama to South Africa from R12 768

PTY — JNB
Dec 2 — Dec 91
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa

Sat 7/119:11 -
1 stop23h 59m
Sat 14/1120:50 -
1 stop30h 12m
Deal found 31/10R16 390
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 291
Fri 27/1110:00 -
1 stop25h 35m
Sat 5/1219:45 -
2 stops41h 28m
Deal found 31/10R19 077
Thu 5/1118:48 -
2 stops62h 22m
Mon 30/1119:10 -
2 stops42h 03m
Deal found 29/10R20 863
Mon 2/118:16 -
2 stops27h 19m
Fri 6/1122:00 -
2 stops29h 27m
Deal found 1/11R23 533
Mon 23/1110:00 -
1 stop25h 35m
Fri 27/1122:00 -
1 stop29h 02m
Deal found 1/11R23 600
Mon 2/1118:30 -
3 stops65h 05m
Fri 6/1119:45 -
2 stops36h 35m
Deal found 1/11R25 018
Wed 16/129:25 -
2 stops41h 15m
Wed 23/1219:45 -
2 stops50h 00m
Deal found 1/11R25 603
Thu 26/1121:30 -
1 stop30h 10m
Thu 3/1219:55 -
1 stop30h 50m
Deal found 29/10R26 320
Thu 10/1218:10 -
2 stops32h 30m
Tue 29/1219:45 -
2 stops41h 54m
Deal found 1/11R26 554
Mon 2/119:11 -
1 stop23h 59m
Mon 9/1120:50 -
1 stop30h 12m
Deal found 1/11R27 372
Tue 15/1210:00 -
1 stop25h 00m
Tue 22/1220:50 -
2 stops27h 18m
Deal found 31/10R28 874

Find flight deals from Panama to South Africa

Round-trip from

R16 390

One-way from

R12 768

Popular in

June

Cheapest in

May

Average price

R16 356
United Airlines
  • United Airlines
  • 14/1-29/1
  • 3 total stops
  • 88h 10m total
  • Panama to South Africa
United Airlines
  • United Airlines
  • 8/1-31/12
  • 2 total stops
  • 55h 12m total
  • Panama to South Africa
Highest demand for flights based on searches. 10% potential increase in price (R45 579 potential increase over avg. return price).
Cheapest flight prices on average. 5% potential price decrease (R19 195 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 8/1

19:28-9:40

2 stops55h 12m

Johannesburg OR Tambo

Wed 31/12

0:00-17:00

Nonstop0h 00m

R12 768

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Thu 7/1

22:29-9:40

2 stops52h 11m

Johannesburg OR Tambo

Wed 31/12

0:00-17:00

Nonstop0h 00m

R14 320

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Thu 14/1

16:41-16:10

2 stops64h 29m

Cape Town Intl

Sun 31/1

20:50-5:33

2 stops39h 43m

R16 390

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Tue 12/1

16:41-18:00

2 stops42h 19m

Cape Town Intl

Tue 26/1

20:50-6:37

2 stops40h 47m

R16 390

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 1/2

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Mon 15/2

22:00-20:36

2 stops29h 36m

R16 540

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Tue 2/2

18:44-18:35

2 stops40h 51m

Johannesburg OR Tambo

Mon 15/2

22:00-20:02

1 stop29h 02m

R16 540

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Thu 14/1

8:55-18:35

2 stops26h 40m

Johannesburg OR Tambo

Thu 18/3

15:05-19:02

2 stops34h 57m

R16 573

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Thu 26/11

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Thu 3/12

19:45-20:41

2 stops31h 56m

R17 291

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Tue 12/1

19:28-18:35

2 stops40h 07m

Johannesburg OR Tambo

Tue 23/3

19:45-6:03

2 stops41h 18m

R17 374

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 27/11

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Sat 5/12

19:45-6:13

2 stops41h 28m

R19 077

Flights are sorted by cheapest return flights first.

Deals found on 30/10

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 323). Flying from Panama to South Africa in December is currently the most expensive (average of R26 721). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • How long is the flight from Panama to South Africa?

    For as low as R16 390, United Airlines can have you in South Africa from Panama in 64h 29m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 323). Flying from Panama to South Africa in December is currently the most expensive (average of R26 721). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to South Africa

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Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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