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Cheap flights from Panama to South Africa from R11 181

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Sep 9 — Sep 161
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 August 2026.

Sat 29/822:55 -
1 stop35h 15m
Sun 13/920:00 -
1 stop31h 35m
Deal found 10/8R15 466
Thu 3/99:45 -
2 stops43h 55m
Fri 11/920:00 -
2 stops49h 14m
Deal found 9/8R15 643
Sat 29/817:51 -
2 stops41h 39m
Tue 8/910:25 -
2 stops34h 06m
Deal found 9/8R15 643
Tue 1/99:12 -
2 stops41h 18m
Sun 13/920:00 -
1 stop24h 31m
Deal found 9/8R16 449
Wed 2/922:55 -
2 stops54h 45m
Wed 9/917:55 -
2 stops47h 32m
Deal found 9/8R16 546
Mon 31/89:39 -
2 stops39h 56m
Tue 8/910:25 -
2 stops41h 10m
Deal found 9/8R16 546
Thu 3/918:06 -
2 stops62h 14m
Sat 12/919:50 -
2 stops48h 41m
Deal found 9/8R17 190
Sat 29/819:25 -
2 stops40h 05m
Mon 7/922:00 -
1 stop28h 31m
Deal found 9/8R17 190
Wed 2/99:45 -
2 stops43h 55m
Fri 11/920:00 -
2 stops53h 37m
Deal found 9/8R17 367
Sat 29/822:55 -
1 stop36h 35m
Sat 12/915:05 -
2 stops35h 26m
Deal found 9/8R17 367
Fri 28/818:41 -
1 stop37h 39m
Wed 9/917:55 -
2 stops56h 36m
Deal found 9/8R17 947
Sun 30/89:45 -
1 stop24h 25m
Thu 10/917:55 -
2 stops43h 18m
Deal found 9/8R18 092

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 10 August 2026.

Round-trip from

R15 466

One-way from

R11 181

Popular in

June

Cheapest in

May

Average price

R31 754
United Airlines
  • United Airlines
  • 29/8-8/9
  • 5 total stops
  • 70h 12m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 2/11
  • 2 total stops
  • 46h 04m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (R47 714 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R18 372 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 10 August 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Fri 28/8

9:13-17:10

2 stops24h 57m

Cape Town Intl

Fri 11/9

20:00-18:37

2 stops53h 37m

R15 466

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 7/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Mon 14/9

22:00-10:33

2 stops43h 33m

R17 190
Fastest return journey

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Thu 24/9

9:13-15:20

1 stop23h 07m

Cape Town Intl

Mon 28/9

19:50-19:31

1 stop30h 41m

R18 978

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Thu 5/11

18:48-16:10

2 stops62h 22m

Cape Town Intl

Mon 30/11

19:10-6:13

2 stops42h 03m

R19 816

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sun 27/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Tue 1/12

19:45-13:31

2 stops48h 46m

R19 816

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 28/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Tue 1/12

22:00-20:02

1 stop29h 02m

R20 460

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 11/12

16:41-9:40

2 stops57h 59m

Johannesburg OR Tambo

Fri 15/1

19:45-20:31

2 stops31h 46m

R20 734

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 11/12

22:29-9:40

2 stops52h 11m

Johannesburg OR Tambo

Sun 17/1

19:45-20:38

2 stops31h 53m

R22 265

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 28/9

22:20-10:30

1 stop29h 10m

Johannesburg OR Tambo

Tue 1/12

18:50-20:05

1 stop32h 15m

R22 490

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Thu 20/8

12:04-8:35

2 stops37h 31m

Johannesburg OR Tambo

Sun 23/8

22:00-14:14

2 stops47h 14m

R26 147

Flights are sorted by cheapest return flights first.

Deals found on 7/8

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R15 756). Flying from Panama to South Africa in March is currently the most expensive (average of R28 628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R17 190, United Airlines can have you in South Africa from Panama in 25h 45m. The distance from Panama to South Africa is about 12194 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R15 756). Flying from Panama to South Africa in March is currently the most expensive (average of R28 628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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