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Cheap flights from Panama to South Africa from R9 429

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
May 1 — May 81
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1 April 2026.

Mon 9/1118:37
PTY
-
CPT
2 stops40h 23m
United Airlines
Mon 16/119:30
CPT
-
PTY
2 stops56h 03m
United Airlines
Deal found 30/3R17 954
Fri 28/819:25
PTY
-
JNB
2 stops40h 05m
United Airlines
Thu 10/919:00
JNB
-
PTY
2 stops32h 35m
United Airlines
Deal found 31/3R17 954
Wed 11/119:11
PTY
-
CPT
2 stops39h 29m
United Airlines
Sun 15/1118:45
CPT
-
PTY
2 stops42h 28m
United Airlines
Deal found 27/3R18 636
Wed 23/99:13
PTY
-
CPT
2 stops41h 17m
United Airlines
Wed 14/1017:55
CPT
-
PTY
2 stops50h 27m
United Airlines
Deal found 29/3R18 908
Fri 28/812:04
PTY
-
JNB
2 stops37h 31m
United Airlines
Mon 7/919:00
JNB
-
PTY
2 stops32h 34m
United Airlines
Deal found 31/3R18 908
Thu 14/520:10
PTY
-
CPT
1 stop32h 40m
Turkish Airlines
Tue 19/516:35
CPT
-
PTY
2 stops32h 50m
Turkish Airlines
Deal found 27/3R19 249
Mon 11/522:20
PTY
-
CPT
1 stop30h 30m
Turkish Airlines
Sun 17/516:35
CPT
-
PTY
1 stop34h 50m
Turkish Airlines
Deal found 27/3R19 284
Mon 11/522:20
PTY
-
CPT
1 stop30h 30m
Turkish Airlines
Mon 18/516:35
CPT
-
PTY
2 stops32h 50m
Turkish Airlines
Deal found 27/3R19 608
Sat 9/522:20
PTY
-
CPT
1 stop30h 30m
Turkish Airlines
Sun 24/516:35
CPT
-
PTY
1 stop34h 50m
Turkish Airlines
Deal found 28/3R20 665
Fri 31/715:30
PTY
-
JNB
2 stops44h 00m
United Airlines
Mon 31/819:00
JNB
-
PTY
2 stops31h 31m
United Airlines
Deal found 30/3R21 602
Thu 17/99:13
PTY
-
CPT
2 stops41h 17m
United Airlines
Mon 21/919:50
CPT
-
PTY
2 stops28h 20m
United Airlines
Deal found 30/3R22 677
Sun 31/520:05
PTY
-
JNB
1 stop31h 25m
Turkish Airlines
Tue 30/617:50
JNB
-
PTY
1 stop33h 35m
Turkish Airlines
Deal found 27/3R22 779

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 1 April 2026.

Round-trip from

R17 954

One-way from

R9 429

Popular in

December

Cheapest in

March

Average price

R20 920
United Airlines
  • United Airlines
  • 28/9-8/10
  • 4 total stops
  • 60h 00m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 17/4
  • 2 total stops
  • 48h 09m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 19% potential increase in price (R106 626 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease (R31 872 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 1 April 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 14/5

20:10-11:50

1 stop32h 40m

Cape Town Intl

Tue 19/5

16:35-20:25

1 stop34h 50m

R19 642

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 9/5

22:20-11:50

1 stop30h 30m

Cape Town Intl

Sun 24/5

16:35-20:25

1 stop34h 50m

R20 665

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 31/7

15:30-18:30

2 stops44h 00m

Johannesburg OR Tambo

Mon 31/8

19:00-19:31

2 stops31h 31m

R21 602

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 17/9

9:13-9:30

2 stops41h 17m

Cape Town Intl

Mon 21/9

19:50-17:10

2 stops28h 20m

R22 677

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 9/5

21:41-21:25

2 stops40h 44m

Cape Town Intl

Sun 24/5

18:25-16:50

2 stops29h 25m

R22 932

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 20/4

9:13-15:20

1 stop23h 07m

Cape Town Intl

Mon 27/4

19:50-10:24

2 stops45h 34m

R22 932

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 18/4

18:41-18:30

2 stops40h 49m

Johannesburg OR Tambo

Thu 23/4

19:00-20:41

2 stops56h 41m

R25 251

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 11/5

18:41-9:30

2 stops55h 49m

Cape Town Intl

Sun 17/5

20:00-18:37

2 stops53h 37m

R27 468

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/4

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Tue 5/5

18:00-16:50

2 stops29h 50m

R27 519
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 26/4

9:13-17:10

2 stops24h 57m

Cape Town Intl

Sun 3/5

20:00-20:27

3 stops31h 27m

R28 405

Flights are sorted by cheapest return flights first.

Deals found on 31/3

Showing 1-10 of 25 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R13 657). Flying from Panama to South Africa in December is currently the most expensive (average of R39 215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R19 437, Turkish Airlines can have you in South Africa from Panama in 30h 30m. The distance from Panama to South Africa is about 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R13 657). Flying from Panama to South Africa in December is currently the most expensive (average of R39 215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to OR Tambo flights
San José to OR Tambo flights
Panama City to Cape Town flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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