Cheap flights from Panama to South Africa from R16 184

PTY — JNB
Dec 8 — Dec 151
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa

Sun 27/1223:55 -
1 stop35h 40m
Wed 13/119:45 -
2 stops41h 52m
Deal found 6/11R17 107
Sat 26/1222:29 -
2 stops61h 06m
Thu 14/119:45 -
2 stops49h 37m
Deal found 6/11R18 870
Thu 5/119:11 -
1 stop23h 59m
Mon 30/1120:50 -
2 stops48h 55m
Deal found 4/11R23 238
Sun 27/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R24 902
Sat 26/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops41h 28m
Deal found 5/11R26 666
Wed 23/1218:10 -
2 stops33h 25m
Wed 6/19:20 -
2 stops52h 17m
Deal found 5/11R27 457
Fri 25/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R28 429
Mon 21/128:16 -
2 stops42h 24m
Mon 28/1219:45 -
2 stops55h 50m
Deal found 6/11R28 825
Sun 27/1221:30 -
1 stop30h 10m
Tue 5/119:55 -
1 stop30h 50m
Deal found 5/11R29 566
Wed 23/1218:10 -
2 stops33h 25m
Thu 7/120:05 -
2 stops41h 32m
Deal found 5/11R29 665
Fri 6/1122:29 -
1 stop34h 41m
Fri 13/1120:50 -
1 stop30h 45m
Deal found 5/11R29 814
Thu 24/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R30 011

Find flight deals from Panama to South Africa

Round-trip from

R16 184

Popular in

June

Cheapest in

May

Average price

R16 151
United Airlines
  • United Airlines
  • 7/3-16/3
  • 3 total stops
  • 64h 30m total
  • Panama to South Africa
Highest demand for flights based on searches. 10% potential increase in price (R44 438 potential increase over avg. return price).
Cheapest flight prices on average. 5% potential price decrease (R18 716 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Mon 8/3

9:20-16:10

1 stop23h 50m

Cape Town Intl

Tue 16/3

20:50-20:50

1 stop31h 00m

R16 184

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sun 7/3

23:24-16:10

1 stop33h 46m

Cape Town Intl

Tue 16/3

20:50-20:34

2 stops30h 44m

R16 184

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 1/2

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Sun 28/2

22:00-20:02

1 stop29h 02m

R16 184

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Tue 9/2

12:04-18:35

2 stops47h 31m

Johannesburg OR Tambo

Fri 19/2

19:45-20:31

2 stops31h 46m

R17 189

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sat 26/12

23:55-18:35

1 stop35h 40m

Johannesburg OR Tambo

Thu 14/1

19:45-20:35

2 stops55h 50m

R18 870

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sat 26/12

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Fri 15/1

19:45-20:02

2 stops55h 17m

R18 870

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Tue 13/4

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Fri 23/4

22:00-4:04

1 stop37h 04m

R19 711

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Wed 3/3

10:00-18:00

1 stop25h 00m

Cape Town Intl

Sun 7/3

20:50-20:50

1 stop31h 00m

R19 777

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Wed 27/1

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Sun 31/1

22:00-20:02

1 stop29h 02m

R19 793

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Tue 9/2

18:50-11:00

1 stop33h 10m

Johannesburg OR Tambo

Fri 19/2

18:50-20:05

1 stop32h 15m

R20 766

Flights are sorted by cheapest return flights first.

Deals found on 5/11

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 118). Flying from Panama to South Africa in December is currently the most expensive (average of R26 386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • How long is the flight from Panama to South Africa?

    For as low as R16 184, United Airlines can have you in South Africa from Panama in 23h 50m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 118). Flying from Panama to South Africa in December is currently the most expensive (average of R26 386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to South Africa

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