Find flights
When to book
FAQs

Cheap flights from Panama to South Africa from R11 387

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Aug 20 — Aug 271
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 July 2026.

Fri 30/1019:28
PTY
-
CPT
2 stops37h 42m
United Airlines
Sat 7/1120:50
CPT
-
PTY
2 stops30h 45m
United Airlines
Deal found 20/7R15 843
Thu 17/922:29
PTY
-
CPT
2 stops35h 41m
United Airlines
Sun 4/1018:25
CPT
-
PTY
2 stops32h 06m
United Airlines
Deal found 18/7R16 025
Fri 30/1022:29
PTY
-
CPT
1 stop34h 41m
United Airlines
Fri 6/119:30
CPT
-
PTY
2 stops41h 32m
United Airlines
Deal found 20/7R16 767
Thu 17/98:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Sat 17/1019:00
JNB
-
PTY
2 stops49h 31m
United Airlines
Deal found 19/7R16 767
Tue 1/1210:00
PTY
-
CPT
1 stop25h 00m
United Airlines
Wed 16/129:30
CPT
-
PTY
2 stops56h 03m
United Airlines
Deal found 17/7R18 533
Mon 3/822:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Sat 15/815:05
JNB
-
PTY
2 stops43h 59m
United Airlines
Deal found 18/7R19 556
Fri 7/89:12
PTY
-
CPT
2 stops41h 18m
United Airlines
Fri 14/820:00
CPT
-
PTY
2 stops39h 04m
United Airlines
Deal found 20/7R20 448
Sat 1/88:11
PTY
-
JNB
2 stops41h 24m
United Airlines
Sat 8/815:05
JNB
-
PTY
2 stops35h 26m
United Airlines
Deal found 16/7R20 481
Thu 5/1116:41
PTY
-
CPT
2 stops64h 29m
United Airlines
Mon 30/1118:25
CPT
-
PTY
2 stops32h 37m
United Airlines
Deal found 19/7R21 157
Tue 29/918:27
PTY
-
CPT
2 stops39h 43m
United Airlines
Sat 3/1019:50
CPT
-
PTY
1 stop30h 41m
United Airlines
Deal found 16/7R23 055
Sat 15/818:41
PTY
-
JNB
2 stops40h 49m
United Airlines
Sat 22/815:05
JNB
-
PTY
2 stops35h 26m
United Airlines
Deal found 16/7R23 088
Wed 22/722:29
PTY
-
JNB
2 stops39h 01m
United Airlines
Tue 28/715:05
JNB
-
PTY
2 stops46h 08m
United Airlines
Deal found 19/7R23 121

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 21 July 2026.

Round-trip from

R15 843

One-way from

R11 387

Popular in

June

Cheapest in

May

Average price

R25 365
United Airlines
  • United Airlines
  • 15/1-28/1
  • 3 total stops
  • 96h 31m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 24/8
  • 1 total stop
  • 36h 35m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R56 610 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R19 866 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 21 July 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 31/10

7:55-16:10

2 stops25h 15m

Cape Town Intl

Sat 7/11

20:50-20:02

1 stop30h 12m

R15 843

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 16/1

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Mon 1/2

22:00-20:02

1 stop29h 02m

R15 843
Fastest return journey

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 14/1

8:55-18:35

2 stops26h 40m

Johannesburg OR Tambo

Mon 1/2

22:00-17:08

2 stops26h 08m

R15 843

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 15/1

8:55-18:35

2 stops26h 40m

Johannesburg OR Tambo

Mon 1/2

22:00-20:02

1 stop29h 02m

R15 843

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 11/1

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Thu 28/1

10:25-20:02

2 stops40h 37m

R16 025

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 17/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Sat 17/10

19:00-13:31

2 stops49h 31m

R16 767

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 1/12

10:00-18:00

1 stop25h 00m

Cape Town Intl

Wed 16/12

9:30-10:33

2 stops56h 03m

R18 533

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 15/1

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Fri 22/1

19:45-20:31

2 stops31h 46m

R18 550

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 3/8

19:25-18:30

2 stops40h 05m

Johannesburg OR Tambo

Sat 15/8

15:05-4:04

2 stops43h 59m

R19 556

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 30/11

18:25-20:02

2 stops32h 37m

R21 157

Flights are sorted by cheapest return flights first.

Deals found on 19/7

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, November is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 173). Flying from Panama to South Africa in March is currently the most expensive (average of R29 326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 843, United Airlines can have you in South Africa from Panama in 25h 15m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, November is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 173). Flying from Panama to South Africa in March is currently the most expensive (average of R29 326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.