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Cheap flights from Panama to South Africa from R11 233

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 29/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Sep 14 — Sep 211
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 August 2026.

Wed 26/819:25 -
2 stops36h 55m
Sat 12/919:50 -
1 stop30h 41m
Deal found 10/8R15 539
Fri 23/108:11 -
2 stops25h 59m
Sat 7/1120:50 -
2 stops39h 43m
Deal found 11/8R15 555
Sat 26/99:13 -
1 stop23h 07m
Sat 3/1019:50 -
1 stop30h 41m
Deal found 11/8R15 620
Sat 21/1110:00 -
1 stop25h 35m
Sat 26/1222:00 -
1 stop29h 02m
Deal found 11/8R19 019
Sat 29/89:13 -
1 stop23h 07m
Fri 11/920:00 -
1 stop24h 31m
Deal found 10/8R19 083
Fri 18/99:45 -
1 stop25h 45m
Sat 3/1010:25 -
2 stops40h 06m
Deal found 10/8R19 715
Thu 5/1116:41 -
2 stops64h 29m
Mon 30/1119:10 -
2 stops32h 21m
Deal found 12/8R19 909
Fri 11/1216:41 -
2 stops57h 59m
Fri 15/119:45 -
2 stops31h 46m
Deal found 10/8R20 832
Fri 11/1222:29 -
2 stops52h 11m
Sun 17/119:45 -
2 stops31h 53m
Deal found 10/8R22 369
Mon 2/119:11 -
2 stops26h 24m
Sat 7/1122:00 -
1 stop29h 02m
Deal found 13/8R22 466
Mon 2/1122:00 -
1 stop30h 00m
Fri 6/110:20 -
1 stop26h 45m
Deal found 13/8R22 563
Sat 15/822:55 -
1 stop36h 35m
Sat 22/815:05 -
2 stops43h 59m
Deal found 14/8R22 661

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 15 August 2026.

Round-trip from

R15 539

One-way from

R11 233

Popular in

June

Cheapest in

May

Average price

R31 903
United Airlines
  • United Airlines
  • 26/8-12/9
  • 3 total stops
  • 67h 36m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 29/9
  • 3 total stops
  • 40h 04m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (R47 318 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R18 462 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 15 August 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Fri 23/10

9:45-17:10

1 stop24h 25m

Cape Town Intl

Sat 7/11

20:50-6:37

2 stops40h 47m

R15 555

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sat 26/9

9:45-17:20

2 stops48h 35m

Cape Town Intl

Sat 3/10

19:50-10:33

2 stops45h 43m

R15 733

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sat 21/11

22:29-18:35

2 stops37h 06m

Johannesburg OR Tambo

Sat 26/12

22:00-20:27

2 stops29h 27m

R19 019

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Thu 5/11

18:48-16:10

2 stops62h 22m

Cape Town Intl

Mon 30/11

19:10-6:13

2 stops42h 03m

R19 909

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 11/12

16:41-9:40

2 stops57h 59m

Johannesburg OR Tambo

Fri 15/1

19:45-20:31

2 stops31h 46m

R20 832

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Fri 11/12

22:29-9:40

2 stops52h 11m

Johannesburg OR Tambo

Sun 17/1

19:45-20:38

2 stops31h 53m

R22 369

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Mon 2/11

9:11-18:35

2 stops26h 24m

Johannesburg OR Tambo

Sat 7/11

22:00-10:05

2 stops43h 05m

R22 466
Fastest return journey

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sun 24/1

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Thu 28/1

22:00-20:02

1 stop29h 02m

R22 547

Panama CityJohannesburg

PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo

PTYJNB

Panama City Tocumen Intl

Sun 24/1

18:50-11:00

1 stop33h 10m

Johannesburg OR Tambo

Thu 28/1

18:50-17:10

2 stops29h 20m

R22 580

Panama CityCape Town

PTY Panama City Tocumen Intl - CPT Cape Town Intl

PTYCPT

Panama City Tocumen Intl

Sat 26/9

12:04-17:10

3 stops46h 06m

Cape Town Intl

Wed 30/9

17:55-19:31

2 stops32h 36m

R24 279

Flights are sorted by cheapest return flights first.

Deals found on 11/8

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R15 830). Flying from Panama to South Africa in March is currently the most expensive (average of R28 763). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 555, United Airlines can have you in South Africa from Panama in 24h 25m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R15 830). Flying from Panama to South Africa in March is currently the most expensive (average of R28 763). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to OR Tambo flights
Panama City to Cape Town flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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