Cheap flights from Panama to South Africa from R9 551

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Dec 12 — Dec 191
1 adult
1 adult, Economy, 0 bags

Find flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 November 2025.

Thu 20/118:16PTY - CPT
2 stops24h 54mUnited Airlines
Mon 24/1120:50CPT - PTY
2 stops40h 23mUnited Airlines
Deal found 11/11R17 079
Thu 20/119:11PTY - CPT
1 stop23h 59mLufthansa
Mon 24/1120:50CPT - PTY
1 stop40h 49mLufthansa
Deal found 11/11R17 748
Tue 11/1118:45PTY - JNB
1 stop44h 20mKLM
Tue 18/1123:59JNB - PTY
1 stop23h 31mKLM
Deal found 11/11R21 246
Tue 30/1218:24PTY - JNB
2 stops41h 11mUnited Airlines
Tue 13/119:45JNB - PTY
2 stops49h 15mUnited Airlines
Deal found 10/11R21 692
Tue 11/1115:35PTY - JNB
2 stops44h 00mUnited Airlines
Tue 18/1119:45JNB - PTY
2 stops45h 40mUnited Airlines
Deal found 11/11R25 362
Wed 10/127:56PTY - CPT
2 stops40h 44mUnited Airlines
Wed 17/1220:50CPT - PTY
2 stops30h 37mUnited Airlines
Deal found 9/11R27 282
Tue 11/1114:55PTY - JNB
2 stops35h 35mMultiple Airlines
Tue 18/1115:25JNB - PTY
3 stops40h 15mMultiple Airlines
Deal found 11/11R32 118
Thu 25/129:30PTY - JNB
2 stops41h 00mUnited Airlines
Thu 1/119:45JNB - PTY
2 stops49h 15mUnited Airlines
Deal found 10/11R32 273
Tue 30/1222:20PTY - JNB
1 stop30h 50mMultiple Airlines
Tue 13/123:59JNB - PTY
1 stop26h 56mMultiple Airlines
Deal found 10/11R33 524

Cheap flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 12 November 2025.

Round-trip from

R17 079

One-way from

R9 551

Popular in

December

Cheapest in

June

Average price

R27 300
United Airlines
  • United Airlines
  • 31/1-7/2
  • 3 total stops
  • 54h 36m total
  • Panama to South Africa
United Airlines
  • United Airlines
  • 10/2
  • 2 total stops
  • 26h 05m total
  • Panama to South Africa
Highest demand for flights based on searches. 15% potential increase in price (R90 053 potential increase over avg. return price).
Cheapest flight prices on average. 6% potential price decrease (R28 148 potential savings vs. average return price).
Average for round-trip flights in November 2025

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 12 November 2025.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Panama

Fly to

South Africa

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 1/2

7:55-18:00

2 stops27h 05m

Cape Town Intl

Sun 8/2

20:50-6:13

1 stop40h 23m

R17 079

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 31/1

8:16-16:10

2 stops24h 54m

Cape Town Intl

Sun 8/2

20:50-17:08

2 stops27h 18m

R17 079

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 31/1

8:16-16:10

2 stops24h 54m

Cape Town Intl

Sat 7/2

20:50-19:38

2 stops29h 48m

R17 079

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 28/1

8:16-18:00

2 stops26h 44m

Cape Town Intl

Wed 4/2

20:50-20:35

2 stops30h 45m

R17 079

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 18/4

8:10-17:45

2 stops26h 35m

Johannesburg OR Tambo

Tue 5/5

15:05-13:31

2 stops29h 26m

R17 234

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 15/4

7:55-17:45

2 stops26h 50m

Johannesburg OR Tambo

Tue 5/5

15:05-13:31

2 stops29h 26m

R17 234

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 20/4

7:55-17:45

2 stops26h 50m

Johannesburg OR Tambo

Tue 5/5

15:05-20:35

2 stops36h 30m

R17 234

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 19/4

22:29-17:45

2 stops36h 16m

Johannesburg OR Tambo

Sun 3/5

15:05-20:35

2 stops36h 30m

R17 234

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 16/4

9:11-20:30

2 stops28h 19m

Johannesburg OR Tambo

Sun 3/5

15:05-6:13

2 stops46h 08m

R17 491

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 1/2

22:29-16:10

1 stop34h 41m

Cape Town Intl

Mon 9/2

20:50-17:08

2 stops27h 18m

R17 988

Flights are sorted by cheapest return flights first.

Deals found on 10/11

Showing 1-10 of 31 results
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R13 976). Flying from Panama to South Africa in August is currently the most expensive (average of R23 458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated 12 November 2025.
Get a feel of what it's like to fly with United Airlines from Panama to South Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7,1

Boarding

7,7

Food

6,6

Crew

8,1

Overall

7,4

Comfort

7,3

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Entertainment

7,1

Boarding

7,7

Food

6,6

Crew

8,1

Overall

7,4

Comfort

7,3

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Panama to South Africa?

    For as low as R17 079, United Airlines can have you in South Africa from Panama in 27h 05m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R13 976). Flying from Panama to South Africa in August is currently the most expensive (average of R23 458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Panama to South Africa

Discover the top airline that operate flights from Panama to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 12 November 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR17 392AverageR25 006FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

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Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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