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Cheap flights from Panama to South Africa from R9 090

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Jul 21 — Jul 281
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 June 2026.

Mon 7/915:30
PTY
-
JNB
2 stops44h 00m
United Airlines
Mon 21/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Deal found 21/6R15 188
Thu 22/109:13
PTY
-
CPT
1 stop23h 07m
United Airlines
Mon 26/1020:50
CPT
-
PTY
1 stop29h 12m
United Airlines
Deal found 20/6R15 253
Fri 10/79:45
PTY
-
CPT
1 stop24h 25m
United Airlines
Fri 17/718:00
CPT
-
PTY
2 stops33h 34m
United Airlines
Deal found 20/6R16 092
Tue 21/722:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Wed 29/719:00
JNB
-
PTY
2 stops42h 13m
United Airlines
Deal found 21/6R16 092
Tue 21/722:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Fri 28/819:00
JNB
-
PTY
2 stops32h 41m
United Airlines
Deal found 17/6R16 108
Wed 22/79:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Tue 28/719:00
JNB
-
PTY
2 stops32h 35m
United Airlines
Deal found 17/6R16 125
Thu 29/109:30
PTY
-
JNB
1 stop26h 05m
United Airlines
Mon 2/1119:45
JNB
-
PTY
2 stops31h 49m
United Airlines
Deal found 20/6R16 174
Fri 24/79:45
PTY
-
JNB
2 stops42h 20m
United Airlines
Thu 13/819:00
JNB
-
PTY
2 stops42h 13m
United Airlines
Deal found 17/6R16 289
Wed 8/722:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Mon 3/822:00
JNB
-
PTY
1 stop37h 04m
United Airlines
Deal found 17/6R16 683
Sat 11/79:13
PTY
-
JNB
2 stops26h 17m
United Airlines
Tue 4/819:00
JNB
-
PTY
2 stops40h 04m
United Airlines
Deal found 17/6R16 716
Thu 5/1119:28
PTY
-
CPT
2 stops61h 42m
United Airlines
Mon 30/1119:10
CPT
-
PTY
2 stops49h 21m
United Airlines
Deal found 17/6R20 250
Fri 17/79:45
PTY
-
CPT
1 stop24h 25m
United Airlines
Sat 8/817:55
CPT
-
PTY
2 stops33h 39m
United Airlines
Deal found 18/6R23 061

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 21 June 2026.

Round-trip from

R15 188

One-way from

R9 090

Popular in

June

Cheapest in

May

Average price

R35 323
United Airlines
  • United Airlines
  • 7/9-21/9
  • 3 total stops
  • 72h 31m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 12/7
  • 1 total stop
  • 24h 25m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 14% potential increase in price (R64 060 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R18 684 potential savings vs. average return price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 21 June 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 22/10

9:13-15:20

1 stop23h 07m

Cape Town Intl

Mon 26/10

20:50-19:02

1 stop29h 12m

R15 253

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 7/9

22:55-18:30

1 stop36h 35m

Johannesburg OR Tambo

Mon 21/9

22:00-19:31

1 stop28h 31m

R15 796

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 10/7

9:45-17:10

1 stop24h 25m

Cape Town Intl

Fri 17/7

18:00-20:34

2 stops33h 34m

R16 092

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 30/8

19:25-15:20

2 stops36h 55m

Cape Town Intl

Tue 8/9

17:55-19:31

2 stops32h 36m

R16 108

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 29/10

9:30-18:35

1 stop26h 05m

Johannesburg OR Tambo

Mon 2/11

19:45-20:34

2 stops31h 49m

R16 174

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 22/7

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Tue 28/7

19:00-20:35

2 stops32h 35m

R16 256

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 30/11

19:10-20:35

2 stops56h 25m

R20 250

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 17/7

9:45-17:10

1 stop24h 25m

Cape Town Intl

Fri 24/7

18:00-13:22

2 stops50h 22m

R20 250

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 15/8

22:29-18:30

2 stops37h 01m

Johannesburg OR Tambo

Sat 22/8

19:00-20:34

2 stops32h 34m

R20 842

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 18/7

15:30-17:10

2 stops42h 40m

Cape Town Intl

Sat 25/7

17:55-17:10

2 stops54h 15m

R22 436

Flights are sorted by cheapest return flights first.

Deals found on 17/6

Showing 1-10 of 14 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 295). Flying from Panama to South Africa in December is currently the most expensive (average of R26 151). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 253, United Airlines can have you in South Africa from Panama in 23h 07m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 295). Flying from Panama to South Africa in December is currently the most expensive (average of R26 151). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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