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Cheap flights from Panama to South Africa from R11 339

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Aug 22 — Aug 291
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 July 2026.

Fri 30/1019:28
PTY
-
CPT
2 stops37h 42m
United Airlines
Sat 7/1120:50
CPT
-
PTY
2 stops30h 45m
United Airlines
Deal found 20/7R15 776
Fri 30/1022:29
PTY
-
CPT
1 stop34h 41m
United Airlines
Fri 6/119:30
CPT
-
PTY
2 stops41h 32m
United Airlines
Deal found 20/7R16 696
Thu 17/98:11
PTY
-
JNB
2 stops27h 19m
United Airlines
Sat 17/1019:00
JNB
-
PTY
2 stops49h 31m
United Airlines
Deal found 19/7R16 696
Thu 5/119:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Mon 30/1118:25
CPT
-
PTY
2 stops32h 37m
United Airlines
Deal found 23/7R19 474
Fri 7/89:12
PTY
-
CPT
2 stops41h 18m
United Airlines
Fri 14/820:00
CPT
-
PTY
2 stops39h 04m
United Airlines
Deal found 20/7R20 361
Sat 15/89:13
PTY
-
JNB
2 stops28h 17m
United Airlines
Sat 22/815:05
JNB
-
PTY
2 stops43h 59m
United Airlines
Deal found 22/7R21 232
Tue 29/918:06
PTY
-
CPT
2 stops40h 04m
United Airlines
Sat 3/1019:50
CPT
-
PTY
1 stop30h 41m
United Airlines
Deal found 22/7R22 957
Wed 22/722:29
PTY
-
JNB
2 stops39h 01m
United Airlines
Tue 28/715:05
JNB
-
PTY
2 stops46h 08m
United Airlines
Deal found 19/7R23 023
Thu 17/910:10
PTY
-
JNB
3 stops34h 45m
Multiple Airlines
Sat 17/1014:05
JNB
-
PTY
2 stops57h 55m
Multiple Airlines
Deal found 19/7R35 200

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 23 July 2026.

Round-trip from

R15 776

One-way from

R11 339

Popular in

June

Cheapest in

May

Average price

R25 258
United Airlines
  • United Airlines
  • 30/10-7/11
  • 4 total stops
  • 68h 27m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 24/8
  • 1 total stop
  • 36h 35m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R56 142 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R19 698 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 23 July 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 31/10

7:55-16:10

2 stops25h 15m

Cape Town Intl

Sat 7/11

20:50-20:02

1 stop30h 12m

R15 776

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 30/10

19:28-16:10

2 stops37h 42m

Cape Town Intl

Sat 7/11

20:50-20:35

2 stops30h 45m

R15 776

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 17/9

8:11-18:30

2 stops27h 19m

Johannesburg OR Tambo

Sat 17/10

19:00-13:31

2 stops49h 31m

R16 696

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 15/1

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Fri 22/1

19:45-20:31

2 stops31h 46m

R16 713

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

22:29-18:00

2 stops36h 31m

Cape Town Intl

Mon 30/11

18:25-20:02

2 stops32h 37m

R19 474

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 15/8

9:13-20:30

2 stops28h 17m

Johannesburg OR Tambo

Sat 22/8

15:05-4:04

2 stops43h 59m

R21 232

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 29/9

18:06-17:10

2 stops40h 04m

Cape Town Intl

Sat 3/10

19:50-19:31

1 stop30h 41m

R22 957
Cheapest one-way

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 24/8

22:55-18:30

1 stop36h 35m

R11 339

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 16/9

18:41-15:20

1 stop37h 39m

R11 405
Fastest single journey

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 3/10

9:45-18:30

1 stop25h 45m

R11 405

Flights are sorted by cheapest return flights first.

Deals found on 19/7

Showing 1-10 of 11 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, November is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 105). Flying from Panama to South Africa in March is currently the most expensive (average of R29 202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 776, United Airlines can have you in South Africa from Panama in 25h 15m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, November is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 105). Flying from Panama to South Africa in March is currently the most expensive (average of R29 202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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