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Cheap flights from Panama to South Africa from R14 941

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Oct 16 — Oct 231
1 adult
1 adult, Economy

Cheap flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 16 September 2025.

Round-trip from

R17 266

One-way from

R14 941

Popular in

August

Cheapest in

June

Average price

R27 330
United Airlines
  • United Airlines
  • 6/2-15/2
  • 3 total stops
  • 71h 56m total
  • Panama to South Africa
Search Deals
21/10
  • 21/10
  • 2 total stops
  • 48h 35m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (R98 322 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (R20 196 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Panama to South Africa

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 September 2025.

Tue 28/1018:24PTY - JNB
2 stops41h 11mUnited Airlines
Sun 9/1119:45JNB - PTY
2 stops31h 50mUnited Airlines
Deal found 15/9R18 238
Mon 13/1018:50PTY - CPT
1 stop43h 35mMultiple Airlines
Wed 5/1123:45CPT - PTY
2 stops27h 25mMultiple Airlines
Deal found 15/9R23 062
Wed 15/1018:50PTY - CPT
2 stops43h 40mMultiple Airlines
Wed 22/1014:00CPT - PTY
2 stops34h 45mMultiple Airlines
Deal found 15/9R23 443
Tue 16/915:30PTY - CPT
2 stops42h 40mUnited Airlines
Tue 23/920:00CPT - PTY
2 stops29h 37mUnited Airlines
Deal found 15/9R24 693
Wed 15/1018:50PTY - CPT
2 stops43h 40mKLM
Wed 22/1023:15CPT - PTY
1 stop24h 35mKLM
Deal found 15/9R25 109
Tue 28/1022:20PTY - JNB
1 stop30h 50mMultiple Airlines
Sun 9/1123:59JNB - PTY
2 stops42h 10mMultiple Airlines
Deal found 13/9R25 474
Fri 19/98:03PTY - JNB
2 stops26h 42mUnited Airlines
Sun 21/919:00JNB - PTY
2 stops54h 37mUnited Airlines
Deal found 15/9R25 664
Fri 19/99:45PTY - JNB
1 stop25h 00mMultiple Airlines
Sun 21/915:05JNB - PTY
2 stops29h 26mMultiple Airlines
Deal found 15/9R27 972
Mon 29/129:11PTY - CPT
2 stops39h 29mUnited Airlines
Sat 10/118:45CPT - PTY
2 stops49h 37mUnited Airlines
Deal found 15/9R29 517
Mon 13/109:13PTY - CPT
1 stop23h 07mUnited Airlines
Wed 5/119:30CPT - PTY
2 stops62h 38mUnited Airlines
Deal found 15/9R29 812
Tue 16/922:05PTY - CPT
3 stops32h 55mMultiple Airlines
Tue 23/97:00CPT - PTY
3 stops34h 10mMultiple Airlines
Deal found 15/9R29 916

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 16 September 2025.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Panama

Fly to

South Africa

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 6/2

8:55-16:10

2 stops48h 15m

Cape Town Intl

Sun 15/2

20:50-13:31

1 stop23h 41m

R17 266

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 22/1

9:30-7:40

2 stops39h 10m

Cape Town Intl

Sun 8/2

20:50-13:55

2 stops48h 05m

R17 873

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 28/10

18:24-18:35

2 stops41h 11m

Johannesburg OR Tambo

Sun 9/11

19:45-20:35

2 stops31h 50m

R18 238

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 25/1

9:11-7:40

2 stops39h 29m

Cape Town Intl

Sat 7/2

18:45-6:13

2 stops42h 28m

R18 862

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 23/1

18:41-7:40

2 stops53h 59m

Cape Town Intl

Sat 7/2

18:45-6:13

2 stops42h 28m

R18 862

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:13-16:10

1 stop23h 57m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R19 157

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 8/2

9:45-10:30

3 stops41h 45m

Johannesburg OR Tambo

Wed 11/2

11:10-16:55

2 stops36h 45m

R22 749

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 13/10

18:50-21:25

1 stop43h 35m

Cape Town Intl

Wed 5/11

23:45-20:10

2 stops27h 25m

R23 062

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 15/10

18:50-21:30

2 stops43h 40m

Cape Town Intl

Wed 22/10

14:00-17:45

2 stops34h 45m

R23 443

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 15/2

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Thu 19/2

10:25-13:55

2 stops34h 30m

R25 005

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 19 results
1
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, January is the cheapest month in which you can book a flight from Panama to South Africa (average of R89). Flying from Panama to South Africa in September is currently the most expensive (average of R123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated 16 September 2025.
Get a feel of what it's like to fly with United Airlines from Panama to South Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
8 929 reviews
Check prices

Entertainment

7,1

Comfort

7,3

Boarding

7,7

Overall

7,4

Crew

8,1

Food

6,6

Reviews

1 / 20
4,0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.
United Airlines
7,4
Good
8 929 reviews
United Airlines
7,4
Good
8 929 reviews
Check prices

Entertainment

7,1

Comfort

7,3

Boarding

7,7

Overall

7,4

Crew

8,1

Food

6,6

Reviews

1 / 20
4,0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R17 266, United Airlines can have you in South Africa from Panama in 48h 15m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, January is the cheapest month in which you can book a flight from Panama to South Africa (average of R89). Flying from Panama to South Africa in September is currently the most expensive (average of R123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Cape Town flights
San José to OR Tambo flights
Panama City to OR Tambo flights

Top airline flying from Panama to South Africa

Discover the top airline that operate flights from Panama to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 16 September 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR17 600AverageR24 230FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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