Find flights
When to book
Airlines
FAQs

Cheap flights from Panama to South Africa from R9 210

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Jan 26 — Feb 21
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Best flights from Panama to South Africa
Discover carefully curated flight deals from Panama to South Africa that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 27 December 2025.

Mon 9/218:31PTY - CPT
2 stops33h 29mLufthansa
Mon 16/218:45CPT - PTY
2 stops45h 09mLufthansa
Deal found 26/12R15 456
Mon 16/222:29PTY - CPT
2 stops36h 31mUnited Airlines
Thu 26/220:50CPT - PTY
2 stops30h 45mUnited Airlines
Deal found 25/12R16 605
Mon 2/218:45PTY - JNB
1 stop44h 20mKLM
Mon 9/219:20JNB - PTY
2 stops28h 10mKLM
Deal found 24/12R17 271
Mon 13/421:55PTY - JNB
2 stops40h 25mMultiple Airlines
Mon 20/423:15JNB - PTY
1 stop24h 35mMultiple Airlines
Deal found 25/12R18 138
Mon 16/221:45PTY - CPT
1 stop31h 05mTurkish Airlines
Thu 26/217:15CPT - PTY
1 stop30h 50mTurkish Airlines
Deal found 25/12R18 421
Mon 2/218:31PTY - JNB
2 stops31h 59mLufthansa
Mon 9/219:45JNB - PTY
2 stops44h 09mLufthansa
Deal found 24/12R15 656
Wed 4/211:57PTY - CPT
2 stops45h 13mUnited Airlines
Sun 8/220:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 24/12R16 755
Mon 9/218:31PTY - JNB
2 stops31h 59mLufthansa
Mon 16/219:45JNB - PTY
2 stops44h 09mLufthansa
Deal found 26/12R15 673
Mon 9/218:45PTY - JNB
1 stop44h 20mKLM
Mon 16/219:20JNB - PTY
2 stops28h 10mKLM
Deal found 26/12R17 288
Mon 9/218:45PTY - CPT
1 stop34h 05mTurkish Airlines
Mon 23/217:15CPT - PTY
1 stop30h 50mTurkish Airlines
Deal found 25/12R18 421
Mon 9/218:45PTY - CPT
2 stops28h 05mMultiple Airlines
Mon 16/223:45CPT - PTY
1 stop23h 45mMultiple Airlines
Deal found 26/12R18 437
Wed 18/27:55PTY - JNB
2 stops27h 40mUnited Airlines
Sun 22/219:45JNB - PTY
2 stops41h 28mUnited Airlines
Deal found 24/12R17 688
Mon 13/422:20PTY - JNB
1 stop29h 10mTurkish Airlines
Mon 20/418:00JNB - PTY
1 stop31h 25mTurkish Airlines
Deal found 25/12R18 421
Wed 1/420:05PTY - JNB
1 stop31h 25mTurkish Airlines
Fri 3/418:00JNB - PTY
1 stop33h 25mTurkish Airlines
Deal found 25/12R18 421
Wed 18/38:16PTY - CPT
2 stops25h 44mUnited Airlines
Sun 22/318:45CPT - PTY
2 stops56h 50mUnited Airlines
Deal found 25/12R19 353
Wed 18/318:45PTY - CPT
1 stop34h 05mTurkish Airlines
Sun 22/317:15CPT - PTY
2 stops30h 50mTurkish Airlines
Deal found 26/12R20 120

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 27 December 2025.

Round-trip from

R15 456

One-way from

R9 210

Popular in

December

Cheapest in

September

Average price

R44 653
Lufthansa
  • Lufthansa
  • 9/2-16/2
  • 4 total stops
  • 78h 38m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 15/1
  • 1 total stop
  • 23h 59m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 22% potential increase in price (R119 669 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease (R33 326 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 27 December 2025.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Panama

Fly to

South Africa

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

18:31-11:00

2 stops33h 29m

Cape Town Intl

Mon 16/2

18:45-8:54

2 stops45h 09m

R15 456

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/2

18:31-9:30

2 stops31h 59m

Johannesburg OR Tambo

Mon 9/2

19:45-8:54

2 stops44h 09m

R15 656

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 9/2

18:31-9:30

2 stops31h 59m

Johannesburg OR Tambo

Mon 16/2

19:45-8:54

2 stops44h 09m

R15 673

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 16/2

22:29-18:00

2 stops36h 31m

Cape Town Intl

Thu 26/2

20:50-20:35

2 stops30h 45m

R16 605

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

11:57-16:10

2 stops45h 13m

Cape Town Intl

Sun 8/2

20:50-13:31

1 stop23h 41m

R16 755

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/2

18:45-22:05

1 stop44h 20m

Johannesburg OR Tambo

Mon 9/2

19:20-16:30

2 stops28h 10m

R17 271

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 9/2

18:45-22:05

1 stop44h 20m

Johannesburg OR Tambo

Mon 16/2

19:20-16:30

2 stops28h 10m

R17 288

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 18/2

7:55-18:35

2 stops27h 40m

Johannesburg OR Tambo

Sun 22/2

19:45-6:13

2 stops41h 28m

R17 688

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

21:55-21:20

2 stops40h 25m

Johannesburg OR Tambo

Mon 20/4

23:15-16:50

1 stop24h 35m

R18 138

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 16/2

21:45-11:50

1 stop31h 05m

Cape Town Intl

Thu 26/2

17:15-17:05

1 stop30h 50m

R18 421

Flights are sorted by cheapest return flights first.

Deals found on 25/12

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 908). Flying from Panama to South Africa in November is currently the most expensive (average of R22 834). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated 27 December 2025.
Get a feel of what it's like to fly with United Airlines from Panama to South Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
9 116 reviews
Check prices

Boarding

7,7

Food

6,6

Comfort

7,3

Crew

8,1

Overall

7,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
United Airlines
7,4
Good
9 116 reviews
United Airlines
7,4
Good
9 116 reviews
Check prices

Boarding

7,7

Food

6,6

Comfort

7,3

Crew

8,1

Overall

7,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 456, Lufthansa can have you in South Africa from Panama in 33h 29m. The distance from Panama to South Africa is about 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 908). Flying from Panama to South Africa in November is currently the most expensive (average of R22 834). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Top airline flying from Panama to South Africa

Discover the top airline that operate flights from Panama to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 27 December 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR12 461AverageR17 488FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.