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Cheap flights from Panama to South Africa from R9 537

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Dec 26 — Jan 21
1 adult
1 adult, Economy, 0 bags

Find flight deals from Panama to South Africa

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Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 November 2025.

Tue 9/127:36PTY - CPT
1 stop27h 24mMultiple Airlines
Sat 13/1220:50CPT - PTY
1 stop30h 12mMultiple Airlines
Deal found 24/11R25 213
Tue 9/1210:00PTY - CPT
2 stops38h 40mLufthansa
Sat 13/1220:50CPT - PTY
1 stop30h 12mLufthansa
Deal found 24/11R25 351
Tue 9/1210:00PTY - CPT
2 stops42h 00mUnited Airlines
Sat 13/1220:50CPT - PTY
2 stops30h 37mUnited Airlines
Deal found 24/11R25 506
Fri 28/118:55PTY - JNB
2 stops26h 40mUnited Airlines
Sun 30/1119:45JNB - PTY
2 stops49h 15mUnited Airlines
Deal found 24/11R27 817
Thu 27/112:55PTY - JNB
3 stops28h 45mMultiple Airlines
Sun 30/1115:25JNB - PTY
2 stops32h 30mMultiple Airlines
Deal found 24/11R32 352

Cheap flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 26 November 2025.

Round-trip from

R17 314

One-way from

R9 537

Popular in

December

Cheapest in

June

Average price

R27 455
United Airlines
  • United Airlines
  • 4/2-8/2
  • 3 total stops
  • 56h 15m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 21/1
  • 2 total stops
  • 26h 44m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 15% potential increase in price (R91 213 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease (R28 470 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 26 November 2025.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Panama

Fly to

South Africa

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 4/2

9:30-18:00

2 stops25h 30m

Cape Town Intl

Sun 8/2

20:50-20:35

1 stop30h 45m

R17 314

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 12/5

3:20-8:35

2 stops46h 15m

Johannesburg OR Tambo

Wed 20/5

19:00-16:30

2 stops52h 30m

R17 418

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 23/2

18:45-20:35

2 stops56h 50m

R18 108

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 5/2

9:11-11:05

2 stops42h 54m

Johannesburg OR Tambo

Mon 9/2

19:45-20:35

2 stops31h 50m

R18 349

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 12/2

9:30-7:40

2 stops39h 10m

Cape Town Intl

Mon 23/2

18:45-13:31

2 stops49h 46m

R18 711

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

20:10-10:35

1 stop31h 25m

Johannesburg OR Tambo

Mon 20/4

18:00-18:30

2 stops31h 30m

R21 367

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 8/1

10:26-9:30

2 stops40h 04m

Johannesburg OR Tambo

Thu 15/1

19:45-6:13

2 stops41h 28m

R22 747

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 1/4

22:15-10:35

1 stop29h 20m

Johannesburg OR Tambo

Fri 3/4

18:00-20:20

1 stop33h 20m

R22 764

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

18:50-21:20

1 stop43h 30m

Johannesburg OR Tambo

Mon 20/4

23:15-19:45

2 stops27h 30m

R23 937

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 1/4

12:04-18:30

2 stops23h 26m

Johannesburg OR Tambo

Fri 3/4

19:00-20:35

2 stops56h 35m

R25 489

Flights are sorted by cheapest return flights first.

Deals found on 23/11

Showing 1-10 of 17 results
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R14 055). Flying from Panama to South Africa in August is currently the most expensive (average of R23 592). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated 26 November 2025.
Get a feel of what it's like to fly with United Airlines from Panama to South Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
9 046 reviews
Check prices

Boarding

7,7

Food

6,6

Comfort

7,3

Crew

8,1

Overall

7,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
United Airlines
7,4
Good
9 046 reviews
United Airlines
7,4
Good
9 046 reviews
Check prices

Boarding

7,7

Food

6,6

Comfort

7,3

Crew

8,1

Overall

7,4

Entertainment

7,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R17 314, United Airlines can have you in South Africa from Panama in 25h 30m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R14 055). Flying from Panama to South Africa in August is currently the most expensive (average of R23 592). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Cape Town flights
San José to OR Tambo flights
Panama City to OR Tambo flights

Top airline flying from Panama to South Africa

Discover the top airline that operate flights from Panama to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 26 November 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR12 903AverageR18 107FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

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It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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