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Cheap flights from Panama to South Africa from R9 068

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Jun 22 — Jun 291
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 May 2026.

Mon 12/1018:41
PTY
-
JNB
2 stops40h 49m
United Airlines
Wed 21/1019:00
JNB
-
PTY
2 stops31h 31m
United Airlines
Deal found 22/5R16 129
Thu 3/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Mon 7/919:00
JNB
-
PTY
2 stops32h 35m
United Airlines
Deal found 22/5R16 194
Sun 6/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Sat 12/919:00
JNB
-
PTY
2 stops32h 35m
United Airlines
Deal found 21/5R16 738
Wed 2/129:11
PTY
-
CPT
2 stops39h 29m
United Airlines
Sun 6/1218:45
CPT
-
PTY
2 stops41h 25m
United Airlines
Deal found 19/5R16 770
Tue 1/922:55
PTY
-
CPT
2 stops54h 45m
United Airlines
Tue 8/917:55
CPT
-
PTY
2 stops47h 29m
United Airlines
Deal found 19/5R16 919
Wed 22/79:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Tue 28/719:00
JNB
-
PTY
2 stops40h 04m
United Airlines
Deal found 20/5R17 626
Mon 1/618:41
PTY
-
JNB
2 stops64h 49m
United Airlines
Mon 15/619:00
JNB
-
PTY
2 stops49h 22m
United Airlines
Deal found 23/5R18 515
Mon 7/99:13
PTY
-
CPT
1 stop23h 07m
United Airlines
Sun 29/1119:10
CPT
-
PTY
2 stops56h 17m
United Airlines
Deal found 22/5R20 260
Sun 21/69:45
PTY
-
CPT
2 stops43h 55m
United Airlines
Sun 28/617:55
CPT
-
PTY
2 stops47h 38m
United Airlines
Deal found 22/5R20 441
Thu 5/119:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Mon 30/1119:10
CPT
-
PTY
2 stops32h 24m
United Airlines
Deal found 23/5R22 465
Wed 20/518:31
PTY
-
JNB
2 stops31h 04m
Lufthansa
Wed 27/519:00
JNB
-
PTY
2 stops42h 48m
Lufthansa
Deal found 19/5R23 238
Sat 15/822:29
PTY
-
JNB
2 stops37h 01m
United Airlines
Sat 22/819:00
JNB
-
PTY
2 stops32h 34m
United Airlines
Deal found 20/5R24 390

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 23 May 2026.

Round-trip from

R16 129

One-way from

R9 068

Popular in

August

Cheapest in

May

Average price

R16 129
United Airlines
  • United Airlines
  • 12/10-21/10
  • 4 total stops
  • 72h 20m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 24/8
  • 2 total stops
  • 64h 05m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (R73 485 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (R17 082 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 23 May 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 12/10

18:41-18:30

2 stops40h 49m

Johannesburg OR Tambo

Wed 21/10

19:00-19:31

2 stops31h 31m

R16 129

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 3/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Mon 7/9

19:00-20:35

2 stops32h 35m

R16 194

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 6/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Sat 12/9

19:00-20:35

2 stops32h 35m

R16 738

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 22/7

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Tue 28/7

19:00-4:04

2 stops40h 04m

R17 626

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 30/11

19:10-20:34

2 stops32h 24m

R22 465
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 13/9

9:45-17:10

1 stop24h 25m

Cape Town Intl

Thu 17/9

19:50-19:31

1 stop30h 41m

R28 390
Cheapest one-way

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 24/8

19:25-18:30

2 stops64h 05m

R9 068

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 11/9

18:41-15:20

1 stop37h 39m

R9 101

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 6/9

8:11-15:20

2 stops48h 09m

R9 101
Fastest single journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 7/9

9:13-15:20

1 stop23h 07m

R9 101

Flights are sorted by cheapest return flights first.

Deals found on 18/5

Showing 1-10 of 15 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 310). Flying from Panama to South Africa in July is currently the most expensive (average of R19 865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R16 129, United Airlines can have you in South Africa from Panama in 40h 49m. The distance from Panama to South Africa is about 12194 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 310). Flying from Panama to South Africa in July is currently the most expensive (average of R19 865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to OR Tambo flights
San José to OR Tambo flights
Panama City to Cape Town flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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