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Cheap flights from Panama to South Africa from R9 140

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Feb 12 — Feb 191
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 13 January 2026.

Round-trip from

R15 425

One-way from

R9 140

Popular in

December

Cheapest in

January

Average price

R17 280
Lufthansa
  • Lufthansa
  • 2/3-8/3
  • 4 total stops
  • 73h 49m total
  • Panama to South Africa
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United Airlines
  • United Airlines
  • 10/2
  • 2 total stops
  • 26h 05m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 19% potential increase in price (R99 138 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease (R32 518 potential savings vs. average return price).
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Average for round-trip flights in January 2026
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Find flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 January 2026.

Mon 2/318:31
PTY
-
JNB
2 stops31h 59m
Lufthansa
Sun 8/319:45
JNB
-
PTY
2 stops41h 50m
Lufthansa
Deal found 12/1R15 425
Fri 30/18:55
PTY
-
CPT
2 stops26h 05m
United Airlines
Wed 4/220:50
CPT
-
PTY
2 stops30h 45m
United Airlines
Deal found 12/1R16 328
Fri 30/18:10
PTY
-
CPT
2 stops26h 50m
United Airlines
Fri 6/220:50
CPT
-
PTY
2 stops30h 37m
United Airlines
Deal found 12/1R16 361
Sun 29/318:41
PTY
-
CPT
1 stop37h 39m
United Airlines
Thu 16/419:50
CPT
-
PTY
2 stops31h 45m
United Airlines
Deal found 11/1R17 247
Mon 30/317:51
PTY
-
CPT
2 stops56h 39m
United Airlines
Thu 16/419:50
CPT
-
PTY
2 stops41h 23m
United Airlines
Deal found 11/1R17 296
Sun 22/322:29
PTY
-
JNB
2 stops37h 06m
United Airlines
Tue 31/319:00
JNB
-
PTY
2 stops32h 41m
United Airlines
Deal found 12/1R17 296
Mon 2/321:45
PTY
-
JNB
1 stop30h 05m
Turkish Airlines
Sun 8/319:05
JNB
-
PTY
1 stop31h 45m
Turkish Airlines
Deal found 12/1R17 378
Wed 18/27:55
PTY
-
JNB
2 stops27h 40m
United Airlines
Sun 22/219:45
JNB
-
PTY
2 stops41h 28m
United Airlines
Deal found 11/1R17 444
Mon 13/49:13
PTY
-
JNB
2 stops28h 17m
United Airlines
Mon 20/419:00
JNB
-
PTY
2 stops32h 41m
United Airlines
Deal found 12/1R17 460
Mon 13/421:55
PTY
-
JNB
2 stops40h 25m
KLM
Mon 20/423:15
JNB
-
PTY
1 stop24h 35m
KLM
Deal found 12/1R17 870
Mon 2/322:20
PTY
-
JNB
1 stop30h 50m
Air France
Sun 8/323:59
JNB
-
PTY
2 stops27h 11m
Air France
Deal found 12/1R18 051
Fri 30/110:00
PTY
-
CPT
1 stop25h 00m
Air Canada
Fri 6/220:50
CPT
-
PTY
1 stop23h 41m
Air Canada
Deal found 13/1R18 067

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 13 January 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Panama

Fly to

South Africa

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 30/1

8:55-18:00

2 stops26h 05m

Cape Town Intl

Wed 4/2

20:50-20:35

2 stops30h 45m

R16 328

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 30/1

8:16-18:00

2 stops26h 44m

Cape Town Intl

Fri 6/2

20:50-20:35

2 stops30h 45m

R16 361

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 28/3

19:20-15:20

2 stops61h 00m

Cape Town Intl

Thu 16/4

19:50-6:13

2 stops41h 23m

R17 247

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

22:29-18:30

2 stops37h 01m

Johannesburg OR Tambo

Mon 20/4

19:00-20:41

2 stops32h 41m

R17 296

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sun 22/3

22:29-18:35

2 stops37h 06m

Johannesburg OR Tambo

Tue 31/3

19:00-20:41

2 stops32h 41m

R17 296

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/3

21:45-10:50

1 stop30h 05m

Johannesburg OR Tambo

Sun 8/3

19:05-19:50

1 stop31h 45m

R17 378

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 18/2

7:55-18:35

2 stops27h 40m

Johannesburg OR Tambo

Sun 22/2

19:45-6:13

2 stops41h 28m

R17 444

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 13/4

21:55-21:20

2 stops40h 25m

Johannesburg OR Tambo

Mon 20/4

23:15-16:50

1 stop24h 35m

R17 870

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 2/3

22:20-12:10

1 stop30h 50m

Johannesburg OR Tambo

Sun 8/3

23:59-20:10

2 stops27h 11m

R18 051

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 30/3

9:13-15:20

1 stop23h 07m

Cape Town Intl

Tue 14/4

20:00-14:22

3 stops49h 22m

R18 116

Flights are sorted by cheapest return flights first.

Deals found on 12/1

Showing 1-10 of 23 results
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 931). Flying from Panama to South Africa in November is currently the most expensive (average of R22 498). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated 13 January 2026.
Get a feel of what it's like to fly with United Airlines from Panama to South Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
9 149 reviews
Check prices

Entertainment

7,1

Food

6,6

Overall

7,4

Comfort

7,3

Boarding

7,7

Crew

8,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
United Airlines
7,4
Good
9 149 reviews
United Airlines
7,4
Good
9 149 reviews
Check prices

Entertainment

7,1

Food

6,6

Overall

7,4

Comfort

7,3

Boarding

7,7

Crew

8,1

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R16 328, United Airlines can have you in South Africa from Panama in 26h 05m. The distance from Panama to South Africa is about 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 931). Flying from Panama to South Africa in November is currently the most expensive (average of R22 498). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Top airline flying from Panama to South Africa

Discover the top airline that operate flights from Panama to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 13 January 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR12 278AverageR18 187FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

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Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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