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Cheap flights from Panama to South Africa from R9 025

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Aug 2 — Aug 91
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 July 2026.

Wed 26/89:13
PTY
-
CPT
2 stops24h 57m
United Airlines
Thu 24/919:50
CPT
-
PTY
1 stop30h 41m
United Airlines
Deal found 28/6R15 063
Wed 18/1110:00
PTY
-
JNB
1 stop25h 35m
United Airlines
Thu 26/1122:00
JNB
-
PTY
1 stop29h 02m
United Airlines
Deal found 28/6R15 063
Mon 7/915:30
PTY
-
CPT
2 stops66h 40m
United Airlines
Tue 22/920:00
CPT
-
PTY
1 stop31h 35m
United Airlines
Deal found 2/7R15 080
Mon 14/99:45
PTY
-
CPT
2 stops43h 55m
United Airlines
Mon 26/1020:50
CPT
-
PTY
2 stops44h 43m
United Airlines
Deal found 30/6R15 259
Wed 22/79:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Tue 28/710:25
JNB
-
PTY
2 stops50h 48m
United Airlines
Deal found 2/7R15 259
Fri 10/77:55
PTY
-
CPT
2 stops26h 15m
United Airlines
Thu 16/719:50
CPT
-
PTY
2 stops41h 23m
United Airlines
Deal found 29/6R15 684
Fri 10/79:13
PTY
-
CPT
2 stops24h 57m
United Airlines
Fri 17/718:00
CPT
-
PTY
2 stops47h 24m
United Airlines
Deal found 30/6R15 977
Wed 18/118:55
PTY
-
JNB
2 stops26h 40m
United Airlines
Wed 25/1119:45
JNB
-
PTY
2 stops49h 16m
United Airlines
Deal found 28/6R17 462
Fri 27/1110:00
PTY
-
CPT
1 stop25h 00m
United Airlines
Tue 1/1219:10
CPT
-
PTY
2 stops42h 03m
United Airlines
Deal found 29/6R17 528
Fri 27/1110:00
PTY
-
CPT
1 stop25h 00m
United Airlines
Thu 10/1219:10
CPT
-
PTY
2 stops32h 27m
United Airlines
Deal found 28/6R20 074
Fri 27/1121:45
PTY
-
CPT
1 stop31h 20m
Turkish Airlines
Thu 10/1217:20
CPT
-
PTY
1 stop33h 45m
Turkish Airlines
Deal found 28/6R21 314
Tue 17/1122:29
PTY
-
JNB
2 stops37h 06m
United Airlines
Tue 24/1122:00
JNB
-
PTY
2 stops29h 27m
United Airlines
Deal found 28/6R21 363

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 3 July 2026.

Round-trip from

R15 063

One-way from

R9 025

Popular in

June

Cheapest in

May

Average price

R28 560
United Airlines
  • United Airlines
  • 18/11-26/11
  • 2 total stops
  • 54h 37m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 12/7
  • 1 total stop
  • 24h 25m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (R71 788 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R19 196 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 3 July 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 22/7

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Tue 28/7

10:25-6:13

2 stops50h 48m

R15 259

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 27/11

10:00-18:00

1 stop25h 00m

Cape Town Intl

Tue 1/12

19:10-6:13

2 stops42h 03m

R17 528

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 17/8

9:13-15:20

1 stop23h 07m

Cape Town Intl

Mon 24/8

19:50-13:22

2 stops48h 32m

R19 796

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 30/11

19:10-6:13

2 stops42h 03m

R22 261

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 27/11

21:45-11:00

1 stop30h 15m

Johannesburg OR Tambo

Tue 1/12

18:50-20:05

1 stop32h 15m

R22 701
Fastest return journey

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 27/11

9:11-18:35

2 stops26h 24m

Johannesburg OR Tambo

Tue 1/12

22:00-20:02

1 stop29h 02m

R22 995
Cheapest one-way
Fastest single journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 12/7

9:45-17:10

1 stop24h 25m

R9 025

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 3/10

9:45-18:30

1 stop25h 45m

R9 025

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 24/8

18:41-18:30

2 stops64h 49m

R9 123

Flights are sorted by cheapest return flights first.

Deals found on 29/6

Sorted by cheapest first

Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 207). Flying from Panama to South Africa in December is currently the most expensive (average of R25 965). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 259, United Airlines can have you in South Africa from Panama in 25h 45m. The distance from Panama to South Africa is about 12194 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 207). Flying from Panama to South Africa in December is currently the most expensive (average of R25 965). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Cape Town flights
San José to OR Tambo flights
Panama City to OR Tambo flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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