Cheap flights from Panama to South Africa from R16 187
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Dec 8 — Dec 151
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheap flight deals from Panama to South Africa
Enter your travel dates to find the best prices.
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Best
Last-minute
One-way
Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 8 November 2026.
Sun 27/1223:55 -
1 stop35h 40m
Wed 13/119:45 -
2 stops41h 52m
Deal found 6/11R17 110
Sat 26/1222:29 -
2 stops61h 06m
Thu 14/119:45 -
2 stops49h 37m
Deal found 6/11R18 873
Thu 5/119:11 -
1 stop23h 59m
Mon 30/1120:50 -
2 stops48h 55m
Deal found 4/11R23 241
Sun 27/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R24 906
Sat 26/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops41h 28m
Deal found 5/11R26 670
Wed 23/1218:10 -
2 stops33h 25m
Wed 6/19:20 -
2 stops52h 17m
Deal found 5/11R27 461
Fri 25/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R28 434
Mon 21/128:16 -
2 stops42h 24m
Mon 28/1219:45 -
2 stops55h 50m
Deal found 6/11R28 829
Sun 27/1221:30 -
1 stop30h 10m
Tue 5/119:55 -
1 stop30h 50m
Deal found 5/11R29 571
Wed 23/1218:10 -
2 stops33h 25m
Thu 7/120:05 -
2 stops41h 32m
Deal found 5/11R29 670
Fri 6/1122:29 -
1 stop34h 41m
Fri 13/1120:50 -
1 stop30h 45m
Deal found 5/11R29 818
Thu 24/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R30 016
Best flights from Panama to South Africa
Discover carefully curated flight deals from Panama to South Africa that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 8 November 2026.
Mon 8/39:20 -
1 stop23h 50m
Tue 16/320:50 -
1 stop31h 00m
Deal found 6/11R16 187
Tue 9/218:50 -
1 stop33h 10m
Fri 19/218:50 -
1 stop32h 15m
Deal found 5/11R20 769
Sun 14/221:55 -
1 stop41h 45m
Sat 20/27:30 -
1 stop40h 00m
Deal found 6/11R21 280
Sun 7/323:24 -
1 stop33h 46m
Tue 16/320:50 -
2 stops30h 44m
Deal found 6/11R16 187
Mon 1/210:00 -
1 stop25h 35m
Sun 28/222:00 -
1 stop29h 02m
Deal found 7/11R16 187
Tue 9/212:04 -
2 stops47h 31m
Fri 19/219:45 -
2 stops31h 46m
Deal found 5/11R17 192
Sat 26/1223:55 -
1 stop35h 40m
Thu 14/119:45 -
2 stops55h 50m
Deal found 6/11R18 873
Sat 26/1210:00 -
1 stop25h 35m
Fri 15/119:45 -
2 stops55h 17m
Deal found 6/11R18 873
Tue 13/49:45 -
1 stop25h 45m
Fri 23/422:00 -
1 stop37h 04m
Deal found 5/11R19 714
Wed 3/310:00 -
1 stop25h 00m
Sun 7/320:50 -
1 stop31h 00m
Deal found 6/11R19 780
Wed 27/110:00 -
1 stop25h 35m
Sun 31/122:00 -
1 stop29h 02m
Deal found 7/11R19 796
Mon 19/49:20 -
1 stop23h 00m
Fri 23/420:00 -
1 stop31h 50m
Deal found 3/11R23 307
Tue 22/129:25 -
2 stops42h 10m
Sun 10/120:50 -
1 stop23h 41m
Deal found 5/11R42 889
Last-minute flights from Panama to South Africa
Discover last-minute flight deals from Panama to South Africa. Data last updated 8 November 2026 and is based on user searches.
Thu 5/119:11 -
1 stop23h 59m
Mon 30/1120:50 -
1 stop30h 12m
Deal found 4/11R23 241
Fri 6/1122:29 -
1 stop34h 41m
Fri 13/1120:50 -
1 stop30h 45m
Deal found 5/11R29 818
Mon 21/128:16 -
2 stops42h 24m
Mon 28/1219:45 -
2 stops55h 50m
Deal found 6/11R28 829
Wed 23/1218:10 -
2 stops33h 25m
Wed 6/19:20 -
2 stops52h 17m
Deal found 5/11R27 461
Wed 23/1218:10 -
2 stops33h 25m
Thu 7/120:05 -
2 stops41h 32m
Deal found 5/11R29 670
Thu 24/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R30 016
Fri 25/128:55 -
2 stops50h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R28 434
Sat 26/1222:29 -
2 stops61h 06m
Thu 14/119:45 -
2 stops49h 37m
Deal found 6/11R18 873
Sat 26/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops41h 28m
Deal found 5/11R26 670
Sun 27/1223:55 -
1 stop35h 40m
Wed 13/119:45 -
2 stops41h 52m
Deal found 6/11R17 110
Sun 27/1223:55 -
1 stop35h 40m
Sun 10/119:45 -
2 stops31h 53m
Deal found 5/11R24 906
Sun 27/1221:30 -
1 stop30h 10m
Tue 5/119:55 -
1 stop30h 50m
Deal found 5/11R29 571
One-way flights from Panama to South Africa
Search for one-way flight options from Panama to South Africa. Find affordable one-way fares based on user searches. Data last updated 8 November 2026.
Wed 16/122:30 -
3 stops31h 15m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 5/11R23 390
Thu 17/1223:55 -
1 stop35h 05m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 5/11R28 978
Sat 27/221:26 -
3 stops33h 39m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 4/11R60 971
Sat 27/218:50 -
1 stop45h 10m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 4/11R63 790
Find flight deals from Panama to South Africa
Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 8 November 2026.
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7 457 451 searches. Data last updated 8 November 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Mon 8/3
9:20-16:10
1 stop23h 50m
Cape Town Intl
Tue 16/3
20:50-20:50
1 stop31h 00m
R16 187
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Sun 7/3
23:24-16:10
1 stop33h 46m
Cape Town Intl
Tue 16/3
20:50-20:34
2 stops30h 44m
R16 187
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Mon 1/2
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Sun 28/2
22:00-20:02
1 stop29h 02m
R16 187
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Tue 9/2
12:04-18:35
2 stops47h 31m
Johannesburg OR Tambo
Fri 19/2
19:45-20:31
2 stops31h 46m
R17 192
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Sat 26/12
23:55-18:35
1 stop35h 40m
Johannesburg OR Tambo
Thu 14/1
19:45-20:35
2 stops55h 50m
R18 873
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Sat 26/12
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Fri 15/1
19:45-20:02
2 stops55h 17m
R18 873
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Tue 13/4
9:45-18:30
1 stop25h 45m
Johannesburg OR Tambo
Fri 23/4
22:00-4:04
1 stop37h 04m
R19 714
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Wed 3/3
10:00-18:00
1 stop25h 00m
Cape Town Intl
Sun 7/3
20:50-20:50
1 stop31h 00m
R19 780
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Wed 27/1
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Sun 31/1
22:00-20:02
1 stop29h 02m
R19 796
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Tue 9/2
18:50-11:00
1 stop33h 10m
Johannesburg OR Tambo
Fri 19/2
18:50-20:05
1 stop32h 15m
R20 769
Flights are sorted by cheapest return flights first.
Deals found on 5/11
Showing 1-10 of 17 resultsSorted by cheapest first
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2
Best time to book a flight from Panama to South Africa
Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
PTY-CPT
PTY-JNB
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to South Africa
PA0-ZA0
PTY-CPT
PTY-JNB
What is the cheapest month to book a flight from Panama to South Africa?
Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 121). Flying from Panama to South Africa in December is currently the most expensive (average of R26 390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Panama to South Africa?
For as low as R16 187, United Airlines can have you in South Africa from Panama in 23h 50m. The distance from Panama to South Africa is about 11294 km.
Can I find deals for flights from Panama to South Africa that include hotel bookings?
Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Panama to South Africa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.
Can I find deals for business class flights from Panama to South Africa?
Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama to South Africa?
Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 121). Flying from Panama to South Africa in December is currently the most expensive (average of R26 390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Panama to South Africa?
900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!
Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.
Can Cheapflights find flights from Panama to South Africa with no change fees?
Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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