Cheap flights from Panama to South Africa from R12 768
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Dec 2 — Dec 91
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheap flight deals from Panama to South Africa
Enter your travel dates to find the best prices.
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 November 2026.
Sat 7/119:11 -
1 stop23h 59m
Sat 14/1120:50 -
1 stop30h 12m
Deal found 31/10R16 390
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 291
Fri 27/1110:00 -
1 stop25h 35m
Sat 5/1219:45 -
2 stops41h 28m
Deal found 31/10R19 077
Thu 5/1118:48 -
2 stops62h 22m
Mon 30/1119:10 -
2 stops42h 03m
Deal found 29/10R20 863
Mon 2/118:16 -
2 stops27h 19m
Fri 6/1122:00 -
2 stops29h 27m
Deal found 1/11R23 533
Mon 23/1110:00 -
1 stop25h 35m
Fri 27/1122:00 -
1 stop29h 02m
Deal found 1/11R23 600
Mon 2/1118:30 -
3 stops65h 05m
Fri 6/1119:45 -
2 stops36h 35m
Deal found 1/11R25 018
Wed 16/129:25 -
2 stops41h 15m
Wed 23/1219:45 -
2 stops50h 00m
Deal found 1/11R25 603
Thu 26/1121:30 -
1 stop30h 10m
Thu 3/1219:55 -
1 stop30h 50m
Deal found 29/10R26 320
Thu 10/1218:10 -
2 stops32h 30m
Tue 29/1219:45 -
2 stops41h 54m
Deal found 1/11R26 554
Mon 2/119:11 -
1 stop23h 59m
Mon 9/1120:50 -
1 stop30h 12m
Deal found 1/11R27 372
Tue 15/1210:00 -
1 stop25h 00m
Tue 22/1220:50 -
2 stops27h 18m
Deal found 31/10R28 874
Best flights from Panama to South Africa
Discover carefully curated flight deals from Panama to South Africa that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 2 November 2026.
Thu 14/116:41 -
2 stops64h 29m
Sun 31/120:50 -
2 stops39h 43m
Deal found 29/10R16 390
Tue 12/116:41 -
2 stops42h 19m
Tue 26/120:50 -
2 stops40h 47m
Deal found 29/10R16 390
Mon 1/210:00 -
1 stop25h 35m
Mon 15/222:00 -
2 stops29h 36m
Deal found 29/10R16 540
Tue 2/218:44 -
2 stops40h 51m
Mon 15/222:00 -
1 stop29h 02m
Deal found 30/10R16 540
Thu 14/18:55 -
2 stops26h 40m
Thu 18/315:05 -
2 stops34h 57m
Deal found 31/10R16 573
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 291
Tue 12/119:28 -
2 stops40h 07m
Tue 23/319:45 -
2 stops41h 18m
Deal found 30/10R17 374
Fri 27/1110:00 -
1 stop25h 35m
Sat 5/1219:45 -
2 stops41h 28m
Deal found 31/10R19 077
Wed 3/28:55 -
2 stops26h 05m
Sun 7/220:50 -
2 stops29h 48m
Deal found 29/10R20 178
Mon 19/49:20 -
1 stop23h 00m
Fri 23/420:00 -
1 stop31h 50m
Deal found 1/11R23 600
Mon 23/1110:00 -
1 stop25h 35m
Fri 27/1122:00 -
1 stop29h 02m
Deal found 31/10R23 600
Tue 15/1210:00 -
1 stop25h 00m
Tue 22/1220:50 -
2 stops27h 18m
Deal found 31/10R28 874
Last-minute flights from Panama to South Africa
Discover last-minute flight deals from Panama to South Africa. Data last updated 2 November 2026 and is based on user searches.
Mon 2/118:16 -
2 stops27h 19m
Fri 6/1122:00 -
2 stops29h 27m
Deal found 1/11R23 533
Mon 2/1118:30 -
3 stops65h 05m
Fri 6/1119:45 -
2 stops36h 35m
Deal found 1/11R25 018
Mon 2/119:11 -
1 stop23h 59m
Mon 9/1120:50 -
1 stop30h 12m
Deal found 1/11R27 372
Thu 5/1118:48 -
2 stops62h 22m
Mon 30/1119:10 -
2 stops42h 03m
Deal found 29/10R20 863
Sat 7/119:11 -
1 stop23h 59m
Sat 14/1120:50 -
1 stop30h 12m
Deal found 31/10R16 390
Sat 7/1116:18 -
2 stops31h 07m
Fri 13/110:30 -
3 stops36h 18m
Deal found 31/10R38 471
Mon 23/1110:00 -
1 stop25h 35m
Fri 27/1122:00 -
1 stop29h 02m
Deal found 1/11R23 600
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 291
Thu 26/1121:30 -
1 stop30h 10m
Thu 3/1219:55 -
1 stop30h 50m
Deal found 29/10R26 320
Thu 26/1121:30 -
3 stops34h 10m
Thu 3/1216:40 -
3 stops34h 05m
Deal found 29/10R35 350
Fri 27/1110:00 -
1 stop25h 35m
Sat 5/1219:45 -
2 stops41h 28m
Deal found 31/10R19 077
One-way flights from Panama to South Africa
Search for one-way flight options from Panama to South Africa. Find affordable one-way fares based on user searches. Data last updated 2 November 2026.
Fri 8/119:28 -
2 stops55h 12m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 30/10R12 768
Thu 7/122:29 -
2 stops52h 11m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 30/10R14 320
Thu 7/121:30 -
1 stop30h 10m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 30/10R19 477
Thu 7/18:25 -
2 stops43h 15m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R23 566
Fri 8/121:31 -
3 stops57h 24m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 30/10R24 601
Fri 8/121:55 -
1 stop41h 05m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R35 183
Sun 28/218:35 -
3 stops59h 25m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R50 771
Wed 24/318:35 -
3 stops34h 05m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 31/10R55 378
Sat 27/221:30 -
3 stops56h 30m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R57 264
Wed 24/318:50 -
1 stop34h 15m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 31/10R63 356
Sun 28/218:50 -
1 stop45h 10m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R63 890
Sat 27/218:50 -
1 stop45h 10m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 1/11R65 141
Find flight deals from Panama to South Africa
Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 2 November 2026.
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7 457 451 searches. Data last updated 2 November 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Fri 8/1
19:28-9:40
2 stops55h 12m
Johannesburg OR Tambo
Wed 31/12
0:00-17:00
Nonstop0h 00m
R12 768
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Thu 7/1
22:29-9:40
2 stops52h 11m
Johannesburg OR Tambo
Wed 31/12
0:00-17:00
Nonstop0h 00m
R14 320
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Thu 14/1
16:41-16:10
2 stops64h 29m
Cape Town Intl
Sun 31/1
20:50-5:33
2 stops39h 43m
R16 390
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Tue 12/1
16:41-18:00
2 stops42h 19m
Cape Town Intl
Tue 26/1
20:50-6:37
2 stops40h 47m
R16 390
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Mon 1/2
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Mon 15/2
22:00-20:36
2 stops29h 36m
R16 540
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Tue 2/2
18:44-18:35
2 stops40h 51m
Johannesburg OR Tambo
Mon 15/2
22:00-20:02
1 stop29h 02m
R16 540
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Thu 14/1
8:55-18:35
2 stops26h 40m
Johannesburg OR Tambo
Thu 18/3
15:05-19:02
2 stops34h 57m
R16 573
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Thu 26/11
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Thu 3/12
19:45-20:41
2 stops31h 56m
R17 291
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Tue 12/1
19:28-18:35
2 stops40h 07m
Johannesburg OR Tambo
Tue 23/3
19:45-6:03
2 stops41h 18m
R17 374
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Fri 27/11
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Sat 5/12
19:45-6:13
2 stops41h 28m
R19 077
Flights are sorted by cheapest return flights first.
Deals found on 30/10
Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa
Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
PTY-CPT
PTY-JNB
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to South Africa
PA0-ZA0
PTY-CPT
PTY-JNB
What is the cheapest month to book a flight from Panama to South Africa?
Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 323). Flying from Panama to South Africa in December is currently the most expensive (average of R26 721). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Panama to South Africa?
For as low as R16 390, United Airlines can have you in South Africa from Panama in 64h 29m. The distance from Panama to South Africa is about 11294 km.
Can I find deals for flights from Panama to South Africa that include hotel bookings?
Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Panama to South Africa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.
Can I find deals for business class flights from Panama to South Africa?
Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama to South Africa?
Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 323). Flying from Panama to South Africa in December is currently the most expensive (average of R26 721). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Panama to South Africa?
900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!
Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.
Can Cheapflights find flights from Panama to South Africa with no change fees?
Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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