Cheap flights from Panama to South Africa from R16 323
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Nov 29 — Dec 61
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheap flight deals from Panama to South Africa
Enter your travel dates to find the best prices.
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Best
Last-minute
One-way
Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 October 2026.
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 220
Thu 5/1118:48 -
2 stops62h 22m
Mon 30/1119:10 -
2 stops42h 03m
Deal found 28/10R20 777
Thu 5/1122:30 -
1 stop24h 55m
Mon 30/118:30 -
2 stops39h 00m
Deal found 26/10R22 124
Mon 23/1110:00 -
1 stop25h 35m
Fri 27/1122:00 -
2 stops43h 33m
Deal found 29/10R23 586
Thu 26/1121:30 -
1 stop30h 10m
Thu 3/1219:55 -
1 stop30h 50m
Deal found 29/10R26 213
Tue 15/1218:30 -
2 stops32h 10m
Tue 29/1219:45 -
2 stops41h 54m
Deal found 26/10R34 590
Tue 15/1221:30 -
1 stop30h 10m
Tue 29/1219:55 -
1 stop30h 50m
Deal found 26/10R35 188
Thu 26/1121:30 -
3 stops34h 10m
Thu 3/1216:40 -
3 stops34h 05m
Deal found 29/10R35 205
Thu 5/1118:50 -
2 stops39h 30m
Mon 30/1114:00 -
3 stops34h 10m
Deal found 26/10R61 617
Best flights from Panama to South Africa
Discover carefully curated flight deals from Panama to South Africa that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 30 October 2026.
Tue 12/116:41 -
2 stops42h 19m
Tue 26/120:50 -
2 stops40h 47m
Deal found 29/10R16 323
Sun 24/110:00 -
1 stop25h 35m
Sat 30/119:45 -
2 stops36h 35m
Deal found 27/10R16 605
Sun 31/118:50 -
1 stop33h 10m
Fri 5/20:20 -
1 stop26h 45m
Deal found 26/10R21 243
Thu 14/116:41 -
2 stops64h 29m
Sun 31/120:50 -
1 stop23h 41m
Deal found 29/10R16 323
Mon 18/116:41 -
2 stops42h 19m
Tue 2/220:50 -
1 stop30h 45m
Deal found 27/10R16 323
Sun 31/110:00 -
1 stop25h 35m
Sat 6/219:45 -
2 stops41h 50m
Deal found 27/10R18 384
Mon 1/210:00 -
1 stop25h 35m
Tue 16/222:00 -
1 stop29h 02m
Deal found 27/10R16 323
Mon 1/210:00 -
1 stop25h 35m
Mon 15/222:00 -
2 stops29h 36m
Deal found 29/10R16 472
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 220
Fri 29/110:00 -
1 stop25h 35m
Wed 14/419:00 -
2 stops52h 12m
Deal found 25/10R17 336
Wed 3/210:00 -
1 stop25h 00m
Sun 7/220:50 -
1 stop30h 45m
Deal found 29/10R19 946
Fri 29/110:00 -
1 stop25h 35m
Thu 29/422:00 -
1 stop28h 31m
Deal found 25/10R20 345
Sun 31/110:00 -
1 stop25h 35m
Sat 6/222:00 -
1 stop29h 02m
Deal found 27/10R23 503
Wed 6/110:00 -
1 stop25h 00m
Wed 20/120:50 -
2 stops27h 22m
Deal found 27/10R31 266
Last-minute flights from Panama to South Africa
Discover last-minute flight deals from Panama to South Africa. Data last updated 30 October 2026 and is based on user searches.
Thu 5/1118:48 -
2 stops62h 22m
Mon 30/1119:10 -
2 stops42h 03m
Deal found 29/10R20 777
Thu 5/1122:30 -
1 stop24h 55m
Mon 30/118:30 -
2 stops39h 00m
Deal found 26/10R22 124
Thu 5/1118:50 -
2 stops39h 30m
Mon 30/1114:00 -
3 stops34h 10m
Deal found 26/10R61 617
Mon 23/1110:00 -
1 stop25h 35m
Fri 27/1122:00 -
2 stops43h 33m
Deal found 29/10R23 586
Mon 23/1122:00 -
2 stops35h 05m
Fri 27/1112:20 -
3 stops35h 50m
Deal found 27/10R75 280
Thu 26/1110:00 -
1 stop25h 35m
Thu 3/1219:45 -
2 stops31h 56m
Deal found 29/10R17 220
Thu 26/1121:30 -
1 stop30h 10m
Thu 3/1219:55 -
1 stop30h 50m
Deal found 29/10R26 213
Thu 26/1121:30 -
3 stops34h 10m
Thu 3/1216:40 -
3 stops34h 05m
Deal found 29/10R35 205
One-way flights from Panama to South Africa
Search for one-way flight options from Panama to South Africa. Find affordable one-way fares based on user searches. Data last updated 30 October 2026.
Sat 9/121:48 -
2 stops53h 52m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R17 785
Sun 10/116:41 -
2 stops42h 54m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R18 550
Thu 7/121:30 -
1 stop30h 10m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R19 398
Sun 10/121:31 -
3 stops54h 24m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R21 708
Fri 8/116:41 -
2 stops66h 54m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R22 622
Tue 5/112:03 -
3 stops42h 27m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R23 354
Thu 7/18:25 -
2 stops43h 15m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R23 420
Fri 8/121:31 -
3 stops57h 24m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 28/10R24 467
Sun 28/218:35 -
3 stops59h 25m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R50 563
Sat 27/221:30 -
3 stops56h 30m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R57 029
Sun 28/218:50 -
1 stop45h 10m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R63 628
Sat 27/222:00 -
1 stop31h 05m
Wed 31/120:00 -
Nonstop0h 00m
Deal found 29/10R64 991
Find flight deals from Panama to South Africa
Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 30 October 2026.
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7 457 451 searches. Data last updated 30 October 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Tue 12/1
16:41-18:00
2 stops42h 19m
Cape Town Intl
Tue 26/1
20:50-6:37
2 stops40h 47m
R16 323
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Thu 14/1
16:41-16:10
2 stops64h 29m
Cape Town Intl
Sun 31/1
20:50-13:31
1 stop23h 41m
R16 323
Panama CityCape Town
PTY Panama City Tocumen Intl - CPT Cape Town Intl
PTYCPT
Panama City Tocumen Intl
Mon 18/1
16:41-18:00
2 stops42h 19m
Cape Town Intl
Tue 2/2
20:50-20:35
1 stop30h 45m
R16 323
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Mon 1/2
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Tue 16/2
22:00-20:02
1 stop29h 02m
R16 323
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Mon 1/2
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Mon 15/2
22:00-20:36
2 stops29h 36m
R16 472
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Sun 24/1
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Sat 30/1
19:45-1:20
2 stops36h 35m
R16 605
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Thu 26/11
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Thu 3/12
19:45-20:41
2 stops31h 56m
R17 220
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Fri 29/1
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Wed 14/4
19:00-16:12
2 stops52h 12m
R17 336
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Sat 9/1
21:48-10:40
2 stops53h 52m
Johannesburg OR Tambo
Wed 31/12
0:00-17:00
Nonstop0h 00m
R17 785
Panama CityJohannesburg
PTY Panama City Tocumen Intl - JNB Johannesburg OR Tambo
PTYJNB
Panama City Tocumen Intl
Sun 31/1
10:00-18:35
1 stop25h 35m
Johannesburg OR Tambo
Sat 6/2
19:45-6:35
2 stops41h 50m
R18 384
Flights are sorted by cheapest return flights first.
Deals found on 28/10
Showing 1-10 of 27 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa
Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
PTY-CPT
PTY-JNB
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to South Africa
PA0-ZA0
PTY-CPT
PTY-JNB
What is the cheapest month to book a flight from Panama to South Africa?
Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 256). Flying from Panama to South Africa in November is currently the most expensive (average of R26 744). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Panama to South Africa?
For as low as R16 323, United Airlines can have you in South Africa from Panama in 42h 19m. The distance from Panama to South Africa is about 11294 km.
Can I find deals for flights from Panama to South Africa that include hotel bookings?
Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Panama to South Africa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.
Can I find deals for business class flights from Panama to South Africa?
Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama to South Africa?
Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 256). Flying from Panama to South Africa in November is currently the most expensive (average of R26 744). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Panama to South Africa?
900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!
Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.
Can Cheapflights find flights from Panama to South Africa with no change fees?
Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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