Find flights
When to book
FAQs

Cheap flights from Panama to South Africa from R9 065

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Aug 13 — Aug 201
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 July 2026.

Sun 1/1122:29
PTY
-
CPT
1 stop34h 41m
United Airlines
Thu 12/1120:50
CPT
-
PTY
2 stops30h 37m
United Airlines
Deal found 11/7R15 147
Wed 2/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Tue 15/922:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Deal found 10/7R15 147
Wed 30/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Sun 4/1022:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Deal found 12/7R15 213
Wed 22/718:41
PTY
-
JNB
2 stops63h 44m
United Airlines
Tue 28/722:00
JNB
-
PTY
2 stops53h 35m
United Airlines
Deal found 9/7R15 852
Fri 25/99:45
PTY
-
CPT
1 stop24h 25m
United Airlines
Tue 29/920:00
CPT
-
PTY
2 stops31h 27m
United Airlines
Deal found 12/7R15 901
Thu 27/819:25
PTY
-
JNB
2 stops64h 05m
United Airlines
Thu 15/1010:25
JNB
-
PTY
2 stops40h 06m
United Airlines
Deal found 11/7R15 934
Tue 1/922:55
PTY
-
JNB
1 stop36h 35m
United Airlines
Tue 8/919:00
JNB
-
PTY
2 stops32h 41m
United Airlines
Deal found 10/7R16 049
Fri 7/89:45
PTY
-
CPT
2 stops48h 35m
United Airlines
Fri 14/820:00
CPT
-
PTY
2 stops49h 14m
United Airlines
Deal found 14/7R18 589
Thu 10/920:10
PTY
-
CPT
1 stop32h 40m
Turkish Airlines
Thu 24/916:35
CPT
-
PTY
1 stop34h 50m
Turkish Airlines
Deal found 10/7R19 655

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 14 July 2026.

Round-trip from

R15 147

One-way from

R9 065

Popular in

June

Cheapest in

May

Average price

R25 196
United Airlines
  • United Airlines
  • 1/11-12/11
  • 2 total stops
  • 55h 12m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 3/10
  • 1 total stop
  • 25h 45m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (R55 850 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R19 606 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 14 July 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 10/9

9:13-15:20

1 stop23h 07m

Cape Town Intl

Thu 24/9

19:50-6:13

2 stops41h 23m

R15 147
Fastest return journey

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 30/9

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Sun 4/10

22:00-19:31

1 stop28h 31m

R15 213

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 25/9

9:45-17:10

1 stop24h 25m

Cape Town Intl

Tue 29/9

17:55-20:35

2 stops33h 40m

R16 131

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 7/8

9:45-17:20

2 stops48h 35m

Cape Town Intl

Fri 14/8

20:00-14:14

2 stops49h 14m

R18 589

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

18:50-23:00

1 stop45h 10m

Cape Town Intl

Mon 30/11

17:20-17:10

2 stops30h 50m

R19 655

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 7/8

8:10-18:30

2 stops27h 20m

Johannesburg OR Tambo

Thu 27/8

10:25-19:31

2 stops40h 06m

R20 048

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 15/8

9:13-20:30

2 stops28h 17m

Johannesburg OR Tambo

Sat 22/8

15:05-4:04

2 stops43h 59m

R20 245

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 27/7

18:06-18:30

2 stops41h 24m

Johannesburg OR Tambo

Sun 16/8

19:00-20:31

2 stops32h 31m

R20 786

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Tue 29/9

18:06-17:10

2 stops40h 04m

Cape Town Intl

Sat 3/10

19:50-19:31

1 stop30h 41m

R22 901
Cheapest one-way

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 3/10

9:45-18:30

1 stop25h 45m

R9 065

Flights are sorted by cheapest return flights first.

Deals found on 12/7

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, November is the cheapest month in which you can book a flight from Panama to South Africa (average of R15 131). Flying from Panama to South Africa in December is currently the most expensive (average of R26 081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 147, United Airlines can have you in South Africa from Panama in 23h 07m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, November is the cheapest month in which you can book a flight from Panama to South Africa (average of R15 131). Flying from Panama to South Africa in December is currently the most expensive (average of R26 081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.