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Cheap flights from Panama to South Africa from R11 472

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Sep 2 — Sep 91
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 August 2026.

Sun 30/88:11
PTY
-
CPT
2 stops25h 59m
United Airlines
Sun 6/920:00
CPT
-
PTY
2 stops29h 37m
United Airlines
Deal found 2/8R15 868
Sat 29/88:10
PTY
-
CPT
2 stops50h 00m
United Airlines
Sat 5/917:55
CPT
-
PTY
2 stops43h 42m
United Airlines
Deal found 1/8R16 778
Fri 18/99:45
PTY
-
CPT
1 stop24h 25m
United Airlines
Tue 22/920:00
CPT
-
PTY
1 stop24h 31m
United Airlines
Deal found 28/7R19 472
Fri 6/1110:00
PTY
-
JNB
1 stop25h 35m
United Airlines
Tue 10/1110:25
JNB
-
PTY
2 stops34h 06m
United Airlines
Deal found 31/7R19 654
Fri 18/99:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Sat 3/1022:00
JNB
-
PTY
1 stop28h 31m
United Airlines
Deal found 31/7R19 869
Sat 15/812:04
PTY
-
JNB
2 stops37h 31m
United Airlines
Sat 22/815:05
JNB
-
PTY
2 stops43h 59m
United Airlines
Deal found 29/7R20 480
Thu 5/1122:29
PTY
-
CPT
2 stops36h 31m
United Airlines
Mon 30/1118:25
CPT
-
PTY
2 stops32h 37m
United Airlines
Deal found 29/7R21 158
Sat 1/818:27
PTY
-
CPT
2 stops39h 43m
United Airlines
Sat 8/819:50
CPT
-
PTY
2 stops29h 47m
United Airlines
Deal found 31/7R22 927
Thu 20/89:39
PTY
-
JNB
2 stops39h 56m
United Airlines
Sun 23/822:00
JNB
-
PTY
1 stop37h 04m
United Airlines
Deal found 1/8R22 943
Wed 16/922:20
PTY
-
CPT
1 stop30h 30m
Turkish Airlines
Wed 23/916:35
CPT
-
PTY
1 stop32h 55m
Turkish Airlines
Deal found 29/7R25 257

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 3 August 2026.

Round-trip from

R15 868

One-way from

R11 472

Popular in

June

Cheapest in

May

Average price

R32 580
United Airlines
  • United Airlines
  • 30/8-6/9
  • 4 total stops
  • 55h 36m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 3/9
  • 1 total stop
  • 25h 45m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (R50 233 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (R19 340 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 3 August 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 30/10

19:28-16:10

2 stops37h 42m

Cape Town Intl

Tue 10/11

20:50-20:02

2 stops30h 12m

R15 868

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 29/8

22:55-17:10

1 stop35h 15m

Cape Town Intl

Sat 5/9

17:55-6:37

2 stops43h 42m

R16 778

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 18/9

9:45-17:10

1 stop24h 25m

Cape Town Intl

Tue 22/9

20:00-20:35

1 stop31h 35m

R19 472

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 6/11

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Tue 10/11

10:25-13:31

2 stops34h 06m

R19 654
Fastest return journey

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Fri 18/9

9:13-18:30

2 stops26h 17m

Johannesburg OR Tambo

Sat 3/10

22:00-20:27

2 stops29h 27m

R19 869

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Sat 15/8

12:04-8:35

2 stops37h 31m

Johannesburg OR Tambo

Sat 22/8

15:05-4:04

2 stops43h 59m

R20 480

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 5/11

22:29-18:00

2 stops36h 31m

Cape Town Intl

Mon 30/11

18:25-20:02

2 stops32h 37m

R21 158
Cheapest one-way
Fastest single journey

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 3/9

9:45-18:30

1 stop25h 45m

R11 472

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 24/8

22:55-18:30

1 stop36h 35m

R11 472

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 9/9

12:04-18:30

2 stops47h 26m

R11 472

Flights are sorted by cheapest return flights first.

Deals found on 30/7

Showing 1-10 of 14 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 166). Flying from Panama to South Africa in March is currently the most expensive (average of R29 373). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 868, United Airlines can have you in South Africa from Panama in 37h 42m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, July is the cheapest month in which you can book a flight from Panama to South Africa (average of R16 166). Flying from Panama to South Africa in March is currently the most expensive (average of R29 373). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to Cape Town flights
Panama City to OR Tambo flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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