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Cheap flights from Panama to South Africa from R9 192

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Jun 17 — Jun 241
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 May 2026.

Wed 28/1017:50
PTY
-
CPT
3 stops30h 45m
Multiple Airlines
Sun 8/1118:45
CPT
-
PTY
2 stops36h 55m
Multiple Airlines
Deal found 15/5R15 397
Wed 28/1019:40
PTY
-
CPT
2 stops37h 30m
United Airlines
Sun 8/1120:50
CPT
-
PTY
1 stop23h 41m
United Airlines
Deal found 15/5R15 414
Sun 6/129:45
PTY
-
JNB
3 stops41h 45m
Multiple Airlines
Sat 13/320:15
JNB
-
PTY
2 stops43h 35m
Multiple Airlines
Deal found 17/5R15 597
Mon 8/618:06
PTY
-
CPT
3 stops64h 04m
United Airlines
Mon 15/619:50
CPT
-
PTY
2 stops52h 20m
United Airlines
Deal found 17/5R16 031
Sun 6/1214:55
PTY
-
JNB
3 stops36h 35m
Multiple Airlines
Sun 28/219:45
JNB
-
PTY
2 stops44h 05m
Multiple Airlines
Deal found 15/5R16 031
Mon 8/69:45
PTY
-
JNB
1 stop25h 45m
United Airlines
Sun 14/619:00
JNB
-
PTY
2 stops32h 35m
United Airlines
Deal found 14/5R16 348
Thu 29/109:11
PTY
-
CPT
1 stop23h 59m
United Airlines
Mon 2/1118:45
CPT
-
PTY
2 stops42h 28m
United Airlines
Deal found 13/5R16 431
Tue 13/109:45
PTY
-
CPT
2 stops43h 55m
United Airlines
Tue 27/1018:45
CPT
-
PTY
2 stops42h 28m
United Airlines
Deal found 14/5R16 531
Tue 3/1110:00
PTY
-
CPT
1 stop25h 00m
United Airlines
Tue 17/119:30
CPT
-
PTY
2 stops41h 32m
United Airlines
Deal found 18/5R16 982
Sun 6/128:55
PTY
-
JNB
2 stops41h 35m
United Airlines
Sat 13/319:45
JNB
-
PTY
2 stops39h 25m
United Airlines
Deal found 17/5R17 299
Sun 6/1210:26
PTY
-
JNB
2 stops40h 04m
United Airlines
Sun 28/219:45
JNB
-
PTY
2 stops50h 00m
United Airlines
Deal found 15/5R17 316
Mon 1/69:13
PTY
-
JNB
2 stops40h 22m
United Airlines
Mon 15/619:00
JNB
-
PTY
2 stops42h 13m
United Airlines
Deal found 17/5R17 366

Find flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 18 May 2026.

Round-trip from

R15 397

One-way from

R9 192

Popular in

August

Cheapest in

May

Average price

R16 348
28/10-8/11
  • 28/10-8/11
  • 5 total stops
  • 67h 40m total
  • Panama to South Africa
Search Deals
United Airlines
  • United Airlines
  • 24/8
  • 2 total stops
  • 65h 39m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (R75 500 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (R17 566 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 18 May 2026.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 28/10

19:40-16:10

2 stops37h 30m

Cape Town Intl

Sun 8/11

20:50-13:31

1 stop23h 41m

R15 414

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 8/6

18:06-17:10

3 stops64h 04m

Cape Town Intl

Mon 15/6

19:50-17:10

2 stops52h 20m

R16 031

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Thu 5/11

10:00-18:35

1 stop25h 35m

Johannesburg OR Tambo

Fri 25/12

19:45-20:34

2 stops31h 49m

R16 348

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 8/6

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Sun 14/6

19:00-20:35

2 stops32h 35m

R16 348

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 16/6

18:41-18:30

2 stops64h 49m

Johannesburg OR Tambo

Tue 23/6

19:00-18:37

2 stops54h 37m

R16 348

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Thu 29/10

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 2/11

18:45-6:13

2 stops42h 28m

R16 431

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Fri 9/10

9:45-17:20

2 stops48h 35m

Cape Town Intl

Sat 17/10

17:55-13:22

2 stops50h 27m

R22 253

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Mon 1/6

9:45-18:30

1 stop25h 45m

Johannesburg OR Tambo

Mon 15/6

19:00-20:41

2 stops32h 41m

R22 770

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sat 13/6

22:55-17:10

1 stop35h 15m

Cape Town Intl

Sat 20/6

19:50-4:04

1 stop39h 14m

R23 788
Fastest return journey

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 13/9

9:45-17:10

1 stop24h 25m

Cape Town Intl

Thu 17/9

19:50-19:31

1 stop30h 41m

R23 871

Flights are sorted by cheapest return flights first.

Deals found on 17/5

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 478). Flying from Panama to South Africa in July is currently the most expensive (average of R20 135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R15 414, United Airlines can have you in South Africa from Panama in 37h 30m. The distance from Panama to South Africa is about 11294 km.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R12 478). Flying from Panama to South Africa in July is currently the most expensive (average of R20 135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to OR Tambo flights
Panama City to Cape Town flights
San José to OR Tambo flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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