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Cheap flights from Panama to South Africa from R9 103

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JNB
Dec 5 — Dec 121
1 adult
1 adult, Economy, 0 bags

Find flight deals from Panama to South Africa

Enter your travel dates to find the best prices.

Cheapest flights from Panama to South Africa
Explore the most affordable flight options available from Panama to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 November 2025.

Sun 23/1122:29PTY - CPT
1 stop34h 41mUnited Airlines
Fri 26/1220:50CPT - PTY
1 stop23h 41mUnited Airlines
Deal found 5/11R17 369
Wed 5/1118:45PTY - JNB
1 stop44h 20mKLM
Wed 4/223:59JNB - PTY
1 stop23h 31mKLM
Deal found 4/11R17 700
Wed 5/1118:45PTY - JNB
1 stop44h 20mKLM
Tue 3/219:20JNB - PTY
2 stops28h 10mKLM
Deal found 4/11R18 049
Wed 5/1118:45PTY - JNB
2 stops34h 25mKLM
Thu 5/223:59JNB - PTY
1 stop23h 31mKLM
Deal found 4/11R18 241
Wed 3/128:16PTY - CPT
2 stops26h 44mUnited Airlines
Wed 10/129:30CPT - PTY
2 stops56h 03mUnited Airlines
Deal found 5/11R18 293
Wed 5/1118:45PTY - JNB
2 stops34h 25mAir France
Wed 4/219:20JNB - PTY
2 stops28h 10mAir France
Deal found 4/11R18 590
Tue 2/1219:20PTY - JNB
2 stops55h 10mUnited Airlines
Tue 9/1219:45JNB - PTY
2 stops31h 50mUnited Airlines
Deal found 2/11R19 305
Wed 3/1218:45PTY - CPT
1 stop44h 10mMultiple Airlines
Wed 10/127:55CPT - PTY
1 stop43h 15mMultiple Airlines
Deal found 5/11R20 962
Tue 2/1222:20PTY - JNB
1 stop30h 50mAir France
Tue 9/1219:20JNB - PTY
1 stop31h 50mAir France
Deal found 2/11R22 688
Sat 8/1112:56PTY - CPT
2 stops46h 04mUnited Airlines
Sat 22/1120:50CPT - PTY
2 stops30h 37mUnited Airlines
Deal found 4/11R24 833
Fri 7/118:16PTY - JNB
2 stops27h 19mUnited Airlines
Fri 6/222:00JNB - PTY
2 stops26h 08mUnited Airlines
Deal found 4/11R24 833
Fri 7/119:30PTY - JNB
2 stops26h 05mUnited Airlines
Tue 3/215:05JNB - PTY
2 stops29h 26mUnited Airlines
Deal found 4/11R25 007

Cheap flight deals from Panama to South Africa

Keep the following information in mind while searching for Panama to South Africa flight deals. Data was last updated 5 November 2025.

Round-trip from

R17 369

One-way from

R9 103

Popular in

August

Cheapest in

June

Average price

R27 763
United Airlines
  • United Airlines
  • 9/2-22/2
  • 3 total stops
  • 68h 42m total
  • Panama to South Africa
Search Deals
19/11
  • 19/11
  • 3 total stops
  • 38h 45m total
  • Panama to South Africa
Search Deals
Highest demand for flights based on searches. 17% potential increase in price (R101 891 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (R20 635 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 5 November 2025.
Use the filters below to find and compare flights from Panama to South Africa that are best for you.

Fly from

Panama

Fly to

South Africa

Route

Depart

Return

Price

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:11-16:10

1 stop23h 59m

Cape Town Intl

Sun 22/2

20:50-10:33

2 stops44h 43m

R17 369

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 18/3

8:16-17:00

2 stops25h 44m

Cape Town Intl

Wed 25/3

19:50-20:35

2 stops31h 45m

R18 293

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 3/12

8:16-18:00

2 stops26h 44m

Cape Town Intl

Wed 10/12

9:30-10:33

2 stops56h 03m

R18 293

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

9:11-16:10

1 stop23h 59m

Cape Town Intl

Mon 23/2

18:45-6:13

2 stops42h 28m

R18 328

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 17/2

12:56-18:35

2 stops46h 39m

Johannesburg OR Tambo

Tue 19/5

19:00-20:35

2 stops32h 35m

R18 328

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Wed 28/1

8:16-18:35

2 stops27h 19m

Johannesburg OR Tambo

Wed 25/3

19:45-6:13

2 stops41h 28m

R18 328

Panama CityJohannesburg

PTY - JNB

PTYJNB

Panama City Tocumen Intl

Tue 2/12

19:20-9:30

2 stops55h 10m

Johannesburg OR Tambo

Tue 9/12

19:45-20:35

2 stops31h 50m

R19 305

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Sun 8/2

18:45-5:50

2 stops52h 05m

Cape Town Intl

Thu 12/2

18:25-16:30

2 stops29h 05m

R19 392

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Mon 9/2

18:45-11:50

1 stop34h 05m

Cape Town Intl

Mon 23/2

17:15-17:05

1 stop30h 50m

R20 578

Panama CityCape Town

PTY - CPT

PTYCPT

Panama City Tocumen Intl

Wed 3/12

18:45-21:55

1 stop44h 10m

Cape Town Intl

Wed 10/12

7:55-20:10

1 stop43h 15m

R20 962

Flights are sorted by cheapest return flights first.

Deals found on 3/11

Showing 1-10 of 27 results
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Best time to book a flight from Panama to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to South Africa

What is the cheapest month to book a flight from Panama to South Africa?

Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R14 213). Flying from Panama to South Africa in August is currently the most expensive (average of R23 856). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated 5 November 2025.
Get a feel of what it's like to fly with United Airlines from Panama to South Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7,4
Good
9 002 reviews
Check prices

Crew

8,1

Food

6,6

Comfort

7,3

Overall

7,4

Entertainment

7,1

Boarding

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
United Airlines
7,4
Good
9 002 reviews
United Airlines
7,4
Good
9 002 reviews
Check prices

Crew

8,1

Food

6,6

Comfort

7,3

Overall

7,4

Entertainment

7,1

Boarding

7,7

Reviews

1 / 20
8,0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Panama to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to South Africa?

    For as low as R17 369, United Airlines can have you in South Africa from Panama in 23h 59m. The distance from Panama to South Africa is about 11294 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Panama to South Africa that include hotel bookings?

    Yes. In addition to deals on Panama to South Africa flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to South Africa.

  • Can I find deals for business class flights from Panama to South Africa?

    Yes. Cheapflights offers flight deals from Panama to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to South Africa?

    Currently, September is the cheapest month in which you can book a flight from Panama to South Africa (average of R14 213). Flying from Panama to South Africa in August is currently the most expensive (average of R23 856). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to South Africa

See prices for flight routes from nearby airports that may be better suited for you.
San José to OR Tambo flights
Panama City to OR Tambo flights
Panama City to Cape Town flights

Top airline flying from Panama to South Africa

Discover the top airline that operate flights from Panama to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 594 507 searches. Data last updated 5 November 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapestR17 687AverageR25 430FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to South Africa?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to South Africa from Panama today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama to South Africa?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama to South Africa.

Can Cheapflights find flights from Panama to South Africa with no change fees?

Certainly. Search results for flights to South Africa from Panama shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama to South Africa become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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